Details for: IGF2R

Gene ID: 3482

Symbol: IGF2R

Ensembl ID: ENSG00000197081

Description: insulin like growth factor 2 receptor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 289.4014
    Cell Significance Index: -45.0200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 181.2190
    Cell Significance Index: -45.9700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 103.0320
    Cell Significance Index: -41.8600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 102.0921
    Cell Significance Index: -48.2000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 89.5827
    Cell Significance Index: -46.0800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 71.8307
    Cell Significance Index: -48.2000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 43.8233
    Cell Significance Index: -41.8400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 37.0897
    Cell Significance Index: -45.7300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.0222
    Cell Significance Index: -45.6000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 12.1799
    Cell Significance Index: -37.4100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.9621
    Cell Significance Index: -26.1800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.6737
    Cell Significance Index: -46.0700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 4.0666
    Cell Significance Index: 108.9700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.4780
    Cell Significance Index: 491.7600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4525
    Cell Significance Index: 291.3800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.3399
    Cell Significance Index: 22.5700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.3157
    Cell Significance Index: 36.7700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 1.3063
    Cell Significance Index: 19.6900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1362
    Cell Significance Index: 184.7900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.1093
    Cell Significance Index: 21.6500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.9730
    Cell Significance Index: 54.6000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.8175
    Cell Significance Index: 62.7400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.7894
    Cell Significance Index: 283.1600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7558
    Cell Significance Index: 136.2600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.6901
    Cell Significance Index: 46.4000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.6714
    Cell Significance Index: 82.5500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.6361
    Cell Significance Index: 15.5200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5996
    Cell Significance Index: 27.1800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5260
    Cell Significance Index: 72.2400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.4801
    Cell Significance Index: 12.3400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.4749
    Cell Significance Index: 6.8300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4736
    Cell Significance Index: 258.6500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.4156
    Cell Significance Index: 21.6500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3804
    Cell Significance Index: 10.9600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.3227
    Cell Significance Index: 9.2500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3111
    Cell Significance Index: 59.2000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2900
    Cell Significance Index: 546.0600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2763
    Cell Significance Index: 19.1100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2687
    Cell Significance Index: 185.8100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.2355
    Cell Significance Index: 6.7200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2151
    Cell Significance Index: 10.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1750
    Cell Significance Index: 111.1200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.1621
    Cell Significance Index: 3.4700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1586
    Cell Significance Index: 70.1400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.1334
    Cell Significance Index: 2.4700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.1316
    Cell Significance Index: 1.8900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1224
    Cell Significance Index: 225.6700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1196
    Cell Significance Index: 184.0700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1077
    Cell Significance Index: 18.3900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0880
    Cell Significance Index: 39.9200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0808
    Cell Significance Index: 5.2200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0470
    Cell Significance Index: 63.8700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0412
    Cell Significance Index: 4.0800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0293
    Cell Significance Index: 1.0300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0162
    Cell Significance Index: 11.8800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0037
    Cell Significance Index: -0.0500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0094
    Cell Significance Index: -0.2500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0200
    Cell Significance Index: -14.8500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0238
    Cell Significance Index: -18.0500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0332
    Cell Significance Index: -1.4700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0356
    Cell Significance Index: -22.2200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0414
    Cell Significance Index: -2.1500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0577
    Cell Significance Index: -32.5200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0587
    Cell Significance Index: -3.6100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1110
    Cell Significance Index: -4.2100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1159
    Cell Significance Index: -14.8600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1314
    Cell Significance Index: -27.6800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1341
    Cell Significance Index: -6.7800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1356
    Cell Significance Index: -6.3800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1377
    Cell Significance Index: -39.6300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1385
    Cell Significance Index: -15.8700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1458
    Cell Significance Index: -21.2000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1703
    Cell Significance Index: -17.4000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1713
    Cell Significance Index: -19.5500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2210
    Cell Significance Index: -15.6300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2364
    Cell Significance Index: -27.5500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.2571
    Cell Significance Index: -3.8000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2585
    Cell Significance Index: -33.4000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2764
    Cell Significance Index: -32.6000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2968
    Cell Significance Index: -30.9000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3613
    Cell Significance Index: -4.9300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3817
    Cell Significance Index: -8.2700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.4073
    Cell Significance Index: -8.4500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4210
    Cell Significance Index: -10.5300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4396
    Cell Significance Index: -32.7700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4540
    Cell Significance Index: -9.9400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5109
    Cell Significance Index: -10.8800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5395
    Cell Significance Index: -42.7300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5828
    Cell Significance Index: -18.6700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5967
    Cell Significance Index: -37.6100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6642
    Cell Significance Index: -40.7200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.6991
    Cell Significance Index: -11.9800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.7233
    Cell Significance Index: -4.3700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.7482
    Cell Significance Index: -6.8900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.7693
    Cell Significance Index: -20.9400
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.7828
    Cell Significance Index: -12.6300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.7990
    Cell Significance Index: -41.9500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.8245
    Cell Significance Index: -21.6800
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.9121
    Cell Significance Index: -6.1800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.9419
    Cell Significance Index: -30.0000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** IGF2R is a member of the membrane-bound receptor tyrosine kinase family and is characterized by its unique structure, which includes two extracellular domains, a transmembrane domain, and a cytoplasmic domain. The extracellular domains contain binding sites for IGF-II and other ligands, while the cytoplasmic domain contains tyrosine kinase activity. IGF2R is highly expressed in various tissues, including the adrenal gland, liver, and skeletal muscle, and is also found on the surface of immune cells, such as T cells and macrophages. **Pathways and Functions:** IGF2R is involved in several signaling pathways that regulate cellular behavior, including: 1. **Cell growth and proliferation:** IGF2R binding to IGF-II triggers the activation of the PI3K/Akt pathway, which promotes cell growth and proliferation. 2. **Immune response:** IGF2R is expressed on the surface of immune cells and plays a role in regulating T cell activation and proliferation. 3. **Development:** IGF2R is involved in the development of various tissues, including the adrenal gland, liver, and skeletal muscle. 4. **Apoptosis:** IGF2R can also regulate apoptosis by interacting with pro-apoptotic proteins. **Clinical Significance:** IGF2R has been implicated in several diseases, including: 1. **Cancer:** IGF2R overexpression is associated with various types of cancer, including breast, lung, and colon cancer. 2. **Neurodegenerative diseases:** IGF2R has been implicated in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 3. **Immunological disorders:** IGF2R is involved in the regulation of immune responses and has been implicated in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In conclusion, IGF2R is a multifaceted gene that plays a critical role in regulating various cellular processes, including cell growth, immune response, and development. Its dysregulation has been implicated in several diseases, highlighting the importance of IGF2R in human health and disease. **Significantly expressed cells:** - Cortical cell of adrenal gland - Hepatoblast - Epithelial cell of lower respiratory tract - Chromaffin cell - Endocardial cell - Pigmented epithelial cell - Taste receptor cell - Vascular leptomeningeal cell - Skeletal muscle satellite cell - CD8-positive, alpha-beta cytokine secreting effector T cell **Proteins:** - MPRI_HUMAN (Cation-independent mannose-6-phosphate receptor)

Genular Protein ID: 2275761246

Symbol: MPRI_HUMAN

Name: Cation-independent mannose-6-phosphate receptor

UniProtKB Accession Codes:

P11717 Q7Z7G9 Q96PT5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CPTAC 2 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 6 DrugCentral 1 ELM 1 EMBL 54 EMDB 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 44 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 24 PDBsum 24 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 5 RefSeq 1 SASBDB 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 UniLectin 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2957598

Title: Insulin-like growth factor II receptor as a multifunctional binding protein.

PubMed ID: 2957598

DOI: 10.1038/329301a0

PubMed ID: 2963003

Title: The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells.

PubMed ID: 2963003

DOI: 10.1016/s0021-9258(18)69243-9

PubMed ID: 9892739

Title: Genomic structure of the human M6P/IGF2 receptor.

PubMed ID: 9892739

DOI: 10.1007/s003359900947

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 10900005

Title: Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activation.

PubMed ID: 10900005

DOI: 10.1073/pnas.97.15.8439

PubMed ID: 11387475

Title: Sorting of mannose 6-phosphate receptors mediated by the GGAs.

PubMed ID: 11387475

DOI: 10.1126/science.1060750

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 18817523

Title: Palmitoylation controls recycling in lysosomal sorting and trafficking.

PubMed ID: 18817523

DOI: 10.1111/j.1600-0854.2008.00814.x

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 18046459

Title: Structure and functional analysis of the IGF-II/IGF2R interaction.

PubMed ID: 18046459

DOI: 10.1038/sj.emboj.7601938

Sequence Information:

  • Length: 2491
  • Mass: 274375
  • Checksum: 3841ADE559B48057
  • Sequence:
    • MGAAAGRSPH LGPAPARRPQ RSLLLLQLLL LVAAPGSTQA QAAPFPELCS YTWEAVDTKN 
NVLYKINICG SVDIVQCGPS SAVCMHDLKT RTYHSVGDSV LRSATRSLLE FNTTVSCDQQ 
GTNHRVQSSI AFLCGKTLGT PEFVTATECV HYFEWRTTAA CKKDIFKANK EVPCYVFDEE 
LRKHDLNPLI KLSGAYLVDD SDPDTSLFIN VCRDIDTLRD PGSQLRACPP GTAACLVRGH 
QAFDVGQPRD GLKLVRKDRL VLSYVREEAG KLDFCDGHSP AVTITFVCPS ERREGTIPKL 
TAKSNCRYEI EWITEYACHR DYLESKTCSL SGEQQDVSID LTPLAQSGGS SYISDGKEYL 
FYLNVCGETE IQFCNKKQAA VCQVKKSDTS QVKAAGRYHN QTLRYSDGDL TLIYFGGDEC 
SSGFQRMSVI NFECNKTAGN DGKGTPVFTG EVDCTYFFTW DTEYACVKEK EDLLCGATDG 
KKRYDLSALV RHAEPEQNWE AVDGSQTETE KKHFFINICH RVLQEGKARG CPEDAAVCAV 
DKNGSKNLGK FISSPMKEKG NIQLSYSDGD DCGHGKKIKT NITLVCKPGD LESAPVLRTS 
GEGGCFYEFE WHTAAACVLS KTEGENCTVF DSQAGFSFDL SPLTKKNGAY KVETKKYDFY 
INVCGPVSVS PCQPDSGACQ VAKSDEKTWN LGLSNAKLSY YDGMIQLNYR GGTPYNNERH 
TPRATLITFL CDRDAGVGFP EYQEEDNSTY NFRWYTSYAC PEEPLECVVT DPSTLEQYDL 
SSLAKSEGGL GGNWYAMDNS GEHVTWRKYY INVCRPLNPV PGCNRYASAC QMKYEKDQGS 
FTEVVSISNL GMAKTGPVVE DSGSLLLEYV NGSACTTSDG RQTTYTTRIH LVCSRGRLNS 
HPIFSLNWEC VVSFLWNTEA ACPIQTTTDT DQACSIRDPN SGFVFNLNPL NSSQGYNVSG 
IGKIFMFNVC GTMPVCGTIL GKPASGCEAE TQTEELKNWK PARPVGIEKS LQLSTEGFIT 
LTYKGPLSAK GTADAFIVRF VCNDDVYSGP LKFLHQDIDS GQGIRNTYFE FETALACVPS 
PVDCQVTDLA GNEYDLTGLS TVRKPWTAVD TSVDGRKRTF YLSVCNPLPY IPGCQGSAVG 
SCLVSEGNSW NLGVVQMSPQ AAANGSLSIM YVNGDKCGNQ RFSTRITFEC AQISGSPAFQ 
LQDGCEYVFI WRTVEACPVV RVEGDNCEVK DPRHGNLYDL KPLGLNDTIV SAGEYTYYFR 
VCGKLSSDVC PTSDKSKVVS SCQEKREPQG FHKVAGLLTQ KLTYENGLLK MNFTGGDTCH 
KVYQRSTAIF FYCDRGTQRP VFLKETSDCS YLFEWRTQYA CPPFDLTECS FKDGAGNSFD 
LSSLSRYSDN WEAITGTGDP EHYLINVCKS LAPQAGTEPC PPEAAACLLG GSKPVNLGRV 
RDGPQWRDGI IVLKYVDGDL CPDGIRKKST TIRFTCSESQ VNSRPMFISA VEDCEYTFAW 
PTATACPMKS NEHDDCQVTN PSTGHLFDLS SLSGRAGFTA AYSEKGLVYM SICGENENCP 
PGVGACFGQT RISVGKANKR LRYVDQVLQL VYKDGSPCPS KSGLSYKSVI SFVCRPEARP 
TNRPMLISLD KQTCTLFFSW HTPLACEQAT ECSVRNGSSI VDLSPLIHRT GGYEAYDESE 
DDASDTNPDF YINICQPLNP MHGVPCPAGA AVCKVPIDGP PIDIGRVAGP PILNPIANEI 
YLNFESSTPC LADKHFNYTS LIAFHCKRGV SMGTPKLLRT SECDFVFEWE TPVVCPDEVR 
MDGCTLTDEQ LLYSFNLSSL STSTFKVTRD SRTYSVGVCT FAVGPEQGGC KDGGVCLLSG 
TKGASFGRLQ SMKLDYRHQD EAVVLSYVNG DRCPPETDDG VPCVFPFIFN GKSYEECIIE 
SRAKLWCSTT ADYDRDHEWG FCRHSNSYRT SSIIFKCDED EDIGRPQVFS EVRGCDVTFE 
WKTKVVCPPK KLECKFVQKH KTYDLRLLSS LTGSWSLVHN GVSYYINLCQ KIYKGPLGCS 
ERASICRRTT TGDVQVLGLV HTQKLGVIGD KVVVTYSKGY PCGGNKTASS VIELTCTKTV 
GRPAFKRFDI DSCTYYFSWD SRAACAVKPQ EVQMVNGTIT NPINGKSFSL GDIYFKLFRA 
SGDMRTNGDN YLYEIQLSSI TSSRNPACSG ANICQVKPND QHFSRKVGTS DKTKYYLQDG 
DLDVVFASSS KCGKDKTKSV SSTIFFHCDP LVEDGIPEFS HETADCQYLF SWYTSAVCPL 
GVGFDSENPG DDGQMHKGLS ERSQAVGAVL SLLLVALTCC LLALLLYKKE RRETVISKLT 
TCCRRSSNVS YKYSKVNKEE ETDENETEWL MEEIQLPPPR QGKEGQENGH ITTKSVKALS 
SLHGDDQDSE DEVLTIPEVK VHSGRGAGAE SSHPVRNAQS NALQEREDDR VGLVRGEKAR 
KGKSSSAQQK TVSSTKLVSF HDDSDEDLLH I

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.