Details for: IGF2R

Gene ID: 3482

Symbol: IGF2R

Ensembl ID: ENSG00000197081

Description: insulin like growth factor 2 receptor

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 4.62
    Marker Score: 82,076
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 4.2
    Marker Score: 13,749
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 3.51
    Marker Score: 14,633
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 2.81
    Marker Score: 3,955
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 2.6
    Marker Score: 1,470
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.32
    Marker Score: 9,720
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 2.31
    Marker Score: 1,997
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.25
    Marker Score: 2,586
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 2
    Marker Score: 1,336
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.98
    Marker Score: 854
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 1.98
    Marker Score: 1,506
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 1.96
    Marker Score: 1,608
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.93
    Marker Score: 1,360
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.87
    Marker Score: 30,092
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.81
    Marker Score: 2,000
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.77
    Marker Score: 1,363
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.74
    Marker Score: 3,355
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.73
    Marker Score: 2,152
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.73
    Marker Score: 2,323
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.71
    Marker Score: 500
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 1.7
    Marker Score: 562
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.69
    Marker Score: 25,333
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.69
    Marker Score: 3,718
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.66
    Marker Score: 875
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.63
    Marker Score: 952
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.63
    Marker Score: 4,365
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.62
    Marker Score: 906
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.59
    Marker Score: 1,926
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.59
    Marker Score: 1,515
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.58
    Marker Score: 6,413
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.55
    Marker Score: 1,871
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.55
    Marker Score: 3,642
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.54
    Marker Score: 1,161
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.54
    Marker Score: 56,844
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.54
    Marker Score: 1,656
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.53
    Marker Score: 93,786
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.52
    Marker Score: 1,619
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.52
    Marker Score: 32,351
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 1.5
    Marker Score: 776
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.49
    Marker Score: 50,309
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.49
    Marker Score: 5,284
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.48
    Marker Score: 14,091
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 1.48
    Marker Score: 748
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.46
    Marker Score: 1,534
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 1.44
    Marker Score: 956
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.44
    Marker Score: 3,594
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.43
    Marker Score: 1,621
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.42
    Marker Score: 516
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.41
    Marker Score: 53,567
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.4
    Marker Score: 12,054
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.4
    Marker Score: 819
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.4
    Marker Score: 2,158
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.37
    Marker Score: 820
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.36
    Marker Score: 10,426
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.34
    Marker Score: 912
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 1.33
    Marker Score: 8,099
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.33
    Marker Score: 6,965
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 1.33
    Marker Score: 903
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.32
    Marker Score: 5,118
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.32
    Marker Score: 12,390
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.32
    Marker Score: 880
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.3
    Marker Score: 44,398
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.3
    Marker Score: 13,474
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.3
    Marker Score: 723
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.29
    Marker Score: 297
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.29
    Marker Score: 407
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.28
    Marker Score: 1,809
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.26
    Marker Score: 5,448
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.26
    Marker Score: 363
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.26
    Marker Score: 471
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 1.25
    Marker Score: 6,704
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.25
    Marker Score: 5,173
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.25
    Marker Score: 8,007
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.24
    Marker Score: 1,311
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.21
    Marker Score: 529
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.2
    Marker Score: 652
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.2
    Marker Score: 789
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.19
    Marker Score: 5,862
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.18
    Marker Score: 65,940
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.17
    Marker Score: 492
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.17
    Marker Score: 365
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.16
    Marker Score: 18,217
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.16
    Marker Score: 575
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 1.15
    Marker Score: 3,871
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.15
    Marker Score: 25,774
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.14
    Marker Score: 2,599
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.14
    Marker Score: 2,313
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.14
    Marker Score: 1,466
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.13
    Marker Score: 365
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.13
    Marker Score: 6,074
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.13
    Marker Score: 657
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.13
    Marker Score: 417
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.12
    Marker Score: 767
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.12
    Marker Score: 777
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 1.11
    Marker Score: 464
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.11
    Marker Score: 3,815
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.11
    Marker Score: 350
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.09
    Marker Score: 1,136
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.09
    Marker Score: 1,003
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.09
    Marker Score: 1,105

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** IGF2R is a member of the membrane-bound receptor tyrosine kinase family and is characterized by its unique structure, which includes two extracellular domains, a transmembrane domain, and a cytoplasmic domain. The extracellular domains contain binding sites for IGF-II and other ligands, while the cytoplasmic domain contains tyrosine kinase activity. IGF2R is highly expressed in various tissues, including the adrenal gland, liver, and skeletal muscle, and is also found on the surface of immune cells, such as T cells and macrophages. **Pathways and Functions:** IGF2R is involved in several signaling pathways that regulate cellular behavior, including: 1. **Cell growth and proliferation:** IGF2R binding to IGF-II triggers the activation of the PI3K/Akt pathway, which promotes cell growth and proliferation. 2. **Immune response:** IGF2R is expressed on the surface of immune cells and plays a role in regulating T cell activation and proliferation. 3. **Development:** IGF2R is involved in the development of various tissues, including the adrenal gland, liver, and skeletal muscle. 4. **Apoptosis:** IGF2R can also regulate apoptosis by interacting with pro-apoptotic proteins. **Clinical Significance:** IGF2R has been implicated in several diseases, including: 1. **Cancer:** IGF2R overexpression is associated with various types of cancer, including breast, lung, and colon cancer. 2. **Neurodegenerative diseases:** IGF2R has been implicated in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 3. **Immunological disorders:** IGF2R is involved in the regulation of immune responses and has been implicated in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In conclusion, IGF2R is a multifaceted gene that plays a critical role in regulating various cellular processes, including cell growth, immune response, and development. Its dysregulation has been implicated in several diseases, highlighting the importance of IGF2R in human health and disease. **Significantly expressed cells:** - Cortical cell of adrenal gland - Hepatoblast - Epithelial cell of lower respiratory tract - Chromaffin cell - Endocardial cell - Pigmented epithelial cell - Taste receptor cell - Vascular leptomeningeal cell - Skeletal muscle satellite cell - CD8-positive, alpha-beta cytokine secreting effector T cell **Proteins:** - MPRI_HUMAN (Cation-independent mannose-6-phosphate receptor)

Genular Protein ID: 2275761246

Symbol: MPRI_HUMAN

Name: Cation-independent mannose-6-phosphate receptor

UniProtKB Accession Codes:

P11717 Q7Z7G9 Q96PT5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CPTAC 2 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 5 ELM 1 EMBL 54 EMDB 1 EPD 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 44 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 36 PDBsum 24 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 5 RefSeq 1 SAM 1 SASBDB 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 UniLectin 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2957598

Title: Insulin-like growth factor II receptor as a multifunctional binding protein.

PubMed ID: 2957598

DOI: 10.1038/329301a0

PubMed ID: 2963003

Title: The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells.

PubMed ID: 2963003

DOI: 10.1016/s0021-9258(18)69243-9

PubMed ID: 9892739

Title: Genomic structure of the human M6P/IGF2 receptor.

PubMed ID: 9892739

DOI: 10.1007/s003359900947

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 10900005

Title: Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activation.

PubMed ID: 10900005

DOI: 10.1073/pnas.97.15.8439

PubMed ID: 11387475

Title: Sorting of mannose 6-phosphate receptors mediated by the GGAs.

PubMed ID: 11387475

DOI: 10.1126/science.1060750

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 18817523

Title: Palmitoylation controls recycling in lysosomal sorting and trafficking.

PubMed ID: 18817523

DOI: 10.1111/j.1600-0854.2008.00814.x

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 18046459

Title: Structure and functional analysis of the IGF-II/IGF2R interaction.

PubMed ID: 18046459

DOI: 10.1038/sj.emboj.7601938

Sequence Information:

  • Length: 2491
  • Mass: 274375
  • Checksum: 3841ADE559B48057
  • Sequence:
    • MGAAAGRSPH LGPAPARRPQ RSLLLLQLLL LVAAPGSTQA QAAPFPELCS YTWEAVDTKN 
NVLYKINICG SVDIVQCGPS SAVCMHDLKT RTYHSVGDSV LRSATRSLLE FNTTVSCDQQ 
GTNHRVQSSI AFLCGKTLGT PEFVTATECV HYFEWRTTAA CKKDIFKANK EVPCYVFDEE 
LRKHDLNPLI KLSGAYLVDD SDPDTSLFIN VCRDIDTLRD PGSQLRACPP GTAACLVRGH 
QAFDVGQPRD GLKLVRKDRL VLSYVREEAG KLDFCDGHSP AVTITFVCPS ERREGTIPKL 
TAKSNCRYEI EWITEYACHR DYLESKTCSL SGEQQDVSID LTPLAQSGGS SYISDGKEYL 
FYLNVCGETE IQFCNKKQAA VCQVKKSDTS QVKAAGRYHN QTLRYSDGDL TLIYFGGDEC 
SSGFQRMSVI NFECNKTAGN DGKGTPVFTG EVDCTYFFTW DTEYACVKEK EDLLCGATDG 
KKRYDLSALV RHAEPEQNWE AVDGSQTETE KKHFFINICH RVLQEGKARG CPEDAAVCAV 
DKNGSKNLGK FISSPMKEKG NIQLSYSDGD DCGHGKKIKT NITLVCKPGD LESAPVLRTS 
GEGGCFYEFE WHTAAACVLS KTEGENCTVF DSQAGFSFDL SPLTKKNGAY KVETKKYDFY 
INVCGPVSVS PCQPDSGACQ VAKSDEKTWN LGLSNAKLSY YDGMIQLNYR GGTPYNNERH 
TPRATLITFL CDRDAGVGFP EYQEEDNSTY NFRWYTSYAC PEEPLECVVT DPSTLEQYDL 
SSLAKSEGGL GGNWYAMDNS GEHVTWRKYY INVCRPLNPV PGCNRYASAC QMKYEKDQGS 
FTEVVSISNL GMAKTGPVVE DSGSLLLEYV NGSACTTSDG RQTTYTTRIH LVCSRGRLNS 
HPIFSLNWEC VVSFLWNTEA ACPIQTTTDT DQACSIRDPN SGFVFNLNPL NSSQGYNVSG 
IGKIFMFNVC GTMPVCGTIL GKPASGCEAE TQTEELKNWK PARPVGIEKS LQLSTEGFIT 
LTYKGPLSAK GTADAFIVRF VCNDDVYSGP LKFLHQDIDS GQGIRNTYFE FETALACVPS 
PVDCQVTDLA GNEYDLTGLS TVRKPWTAVD TSVDGRKRTF YLSVCNPLPY IPGCQGSAVG 
SCLVSEGNSW NLGVVQMSPQ AAANGSLSIM YVNGDKCGNQ RFSTRITFEC AQISGSPAFQ 
LQDGCEYVFI WRTVEACPVV RVEGDNCEVK DPRHGNLYDL KPLGLNDTIV SAGEYTYYFR 
VCGKLSSDVC PTSDKSKVVS SCQEKREPQG FHKVAGLLTQ KLTYENGLLK MNFTGGDTCH 
KVYQRSTAIF FYCDRGTQRP VFLKETSDCS YLFEWRTQYA CPPFDLTECS FKDGAGNSFD 
LSSLSRYSDN WEAITGTGDP EHYLINVCKS LAPQAGTEPC PPEAAACLLG GSKPVNLGRV 
RDGPQWRDGI IVLKYVDGDL CPDGIRKKST TIRFTCSESQ VNSRPMFISA VEDCEYTFAW 
PTATACPMKS NEHDDCQVTN PSTGHLFDLS SLSGRAGFTA AYSEKGLVYM SICGENENCP 
PGVGACFGQT RISVGKANKR LRYVDQVLQL VYKDGSPCPS KSGLSYKSVI SFVCRPEARP 
TNRPMLISLD KQTCTLFFSW HTPLACEQAT ECSVRNGSSI VDLSPLIHRT GGYEAYDESE 
DDASDTNPDF YINICQPLNP MHGVPCPAGA AVCKVPIDGP PIDIGRVAGP PILNPIANEI 
YLNFESSTPC LADKHFNYTS LIAFHCKRGV SMGTPKLLRT SECDFVFEWE TPVVCPDEVR 
MDGCTLTDEQ LLYSFNLSSL STSTFKVTRD SRTYSVGVCT FAVGPEQGGC KDGGVCLLSG 
TKGASFGRLQ SMKLDYRHQD EAVVLSYVNG DRCPPETDDG VPCVFPFIFN GKSYEECIIE 
SRAKLWCSTT ADYDRDHEWG FCRHSNSYRT SSIIFKCDED EDIGRPQVFS EVRGCDVTFE 
WKTKVVCPPK KLECKFVQKH KTYDLRLLSS LTGSWSLVHN GVSYYINLCQ KIYKGPLGCS 
ERASICRRTT TGDVQVLGLV HTQKLGVIGD KVVVTYSKGY PCGGNKTASS VIELTCTKTV 
GRPAFKRFDI DSCTYYFSWD SRAACAVKPQ EVQMVNGTIT NPINGKSFSL GDIYFKLFRA 
SGDMRTNGDN YLYEIQLSSI TSSRNPACSG ANICQVKPND QHFSRKVGTS DKTKYYLQDG 
DLDVVFASSS KCGKDKTKSV SSTIFFHCDP LVEDGIPEFS HETADCQYLF SWYTSAVCPL 
GVGFDSENPG DDGQMHKGLS ERSQAVGAVL SLLLVALTCC LLALLLYKKE RRETVISKLT 
TCCRRSSNVS YKYSKVNKEE ETDENETEWL MEEIQLPPPR QGKEGQENGH ITTKSVKALS 
SLHGDDQDSE DEVLTIPEVK VHSGRGAGAE SSHPVRNAQS NALQEREDDR VGLVRGEKAR 
KGKSSSAQQK TVSSTKLVSF HDDSDEDLLH I

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.