Details for: RBPJ
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: acinar cell (CL0000622)
Fold Change: 3.39
Marker Score: 2,388 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 3.09
Marker Score: 7,406 - Cell Name: lung macrophage (CL1001603)
Fold Change: 2.87
Marker Score: 3,281 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 2.71
Marker Score: 3,276 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 2.6
Marker Score: 3,147 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 2.55
Marker Score: 142,840 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.45
Marker Score: 10,260 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.43
Marker Score: 82,756 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 2.37
Marker Score: 3,184 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.22
Marker Score: 1,294 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.17
Marker Score: 1,270 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 2.15
Marker Score: 1,183 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 2.15
Marker Score: 1,122 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.11
Marker Score: 42,016 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 2.09
Marker Score: 53,442 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 2.08
Marker Score: 2,571 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.07
Marker Score: 4,538 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 2.05
Marker Score: 2,667 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 2.04
Marker Score: 1,198 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 2.02
Marker Score: 26,701 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 2.01
Marker Score: 2,481 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 1.99
Marker Score: 1,143 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 1.98
Marker Score: 1,493 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.98
Marker Score: 2,274 - Cell Name: keratocyte (CL0002363)
Fold Change: 1.97
Marker Score: 454 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 1.97
Marker Score: 4,895 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.96
Marker Score: 620 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.95
Marker Score: 41,640 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.94
Marker Score: 4,045 - Cell Name: microglial cell (CL0000129)
Fold Change: 1.93
Marker Score: 3,511 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 1.9
Marker Score: 3,231 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.86
Marker Score: 27,799 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 1.86
Marker Score: 7,751 - Cell Name: secretory cell (CL0000151)
Fold Change: 1.86
Marker Score: 3,387 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 1.84
Marker Score: 1,052 - Cell Name: stromal cell (CL0000499)
Fold Change: 1.84
Marker Score: 2,153 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.83
Marker Score: 69,615 - Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: 1.83
Marker Score: 4,742 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.82
Marker Score: 111,779 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 1.82
Marker Score: 656 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.81
Marker Score: 18,700 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.81
Marker Score: 1,997 - Cell Name: basal cell (CL0000646)
Fold Change: 1.81
Marker Score: 2,333 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.8
Marker Score: 1,896 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 1.79
Marker Score: 2,759 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 1.79
Marker Score: 516 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.78
Marker Score: 2,559 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.77
Marker Score: 1,887 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.76
Marker Score: 1,902 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1.76
Marker Score: 4,150 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.76
Marker Score: 64,818 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 1.75
Marker Score: 1,754 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.75
Marker Score: 3,105 - Cell Name: supporting cell (CL0000630)
Fold Change: 1.75
Marker Score: 3,282 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 1.75
Marker Score: 1,160 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.73
Marker Score: 414 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.73
Marker Score: 16,289 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.72
Marker Score: 13,198 - Cell Name: myelocyte (CL0002193)
Fold Change: 1.71
Marker Score: 738 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.7
Marker Score: 498 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.7
Marker Score: 689 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 1.69
Marker Score: 1,061 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.69
Marker Score: 820 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.69
Marker Score: 1,462 - Cell Name: neuron (CL0000540)
Fold Change: 1.68
Marker Score: 6,854 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.68
Marker Score: 15,978 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.68
Marker Score: 2,475 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.67
Marker Score: 16,850 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.67
Marker Score: 3,220 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 1.67
Marker Score: 3,252 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 1.67
Marker Score: 2,295 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.67
Marker Score: 2,346 - Cell Name: neural crest cell (CL0011012)
Fold Change: 1.67
Marker Score: 1,780 - Cell Name: adventitial cell (CL0002503)
Fold Change: 1.66
Marker Score: 411 - Cell Name: decidual cell (CL2000002)
Fold Change: 1.66
Marker Score: 7,146 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.66
Marker Score: 1,522 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.66
Marker Score: 6,399 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.65
Marker Score: 927 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.65
Marker Score: 6,493 - Cell Name: reticular cell (CL0000432)
Fold Change: 1.65
Marker Score: 602 - Cell Name: neutrophil (CL0000775)
Fold Change: 1.64
Marker Score: 1,001 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.64
Marker Score: 669 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 1.64
Marker Score: 10,474 - Cell Name: elicited macrophage (CL0000861)
Fold Change: 1.64
Marker Score: 9,952 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 1.62
Marker Score: 1,717 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.62
Marker Score: 18,269 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 1.62
Marker Score: 8,493 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.61
Marker Score: 411 - Cell Name: club cell (CL0000158)
Fold Change: 1.61
Marker Score: 1,881 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.61
Marker Score: 2,020 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.61
Marker Score: 25,789 - Cell Name: professional antigen presenting cell (CL0000145)
Fold Change: 1.6
Marker Score: 828 - Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
Fold Change: 1.6
Marker Score: 364 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.59
Marker Score: 13,673 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.59
Marker Score: 876 - Cell Name: podocyte (CL0000653)
Fold Change: 1.58
Marker Score: 586 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 1.58
Marker Score: 4,139 - Cell Name: fibroblast (CL0000057)
Fold Change: 1.58
Marker Score: 1,523 - Cell Name: erythroblast (CL0000765)
Fold Change: 1.58
Marker Score: 984 - Cell Name: radial glial cell (CL0000681)
Fold Change: 1.57
Marker Score: 580
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2136746154
Symbol: SUH_HUMAN
Name: Recombining binding protein suppressor of hairless
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8406481
Title: Human Jk recombination signal binding protein gene (IGKJRB): comparison with its mouse homologue.
PubMed ID: 8406481
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8016657
Title: Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa.
PubMed ID: 8016657
PubMed ID: 8627785
Title: The amino-terminal domains of Epstein-Barr virus nuclear proteins 3A, 3B, and 3C interact with RBPJ(kappa).
PubMed ID: 8627785
PubMed ID: 10508479
Title: Antigens recognized by autologous antibody in patients with renal-cell carcinoma.
PubMed ID: 10508479
DOI: 10.1002/(sici)1097-0215(19991112)83:4<456::aid-ijc4>3.0.co;2-5
PubMed ID: 9874765
Title: CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex.
PubMed ID: 9874765
DOI: 10.1073/pnas.96.1.23
PubMed ID: 10644367
Title: A role for SKIP in EBNA2 activation of CBF1-repressed promoters.
PubMed ID: 10644367
PubMed ID: 10637481
Title: Intracellular forms of human NOTCH1 interact at distinctly different levels with RBP-jkappa in human B and T cells.
PubMed ID: 10637481
PubMed ID: 12374742
Title: SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway.
PubMed ID: 12374742
DOI: 10.1093/emboj/cdf549
PubMed ID: 21102556
Title: RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.
PubMed ID: 21102556
PubMed ID: 21991380
Title: A SILAC-based screen for Methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequence-specific binding protein.
PubMed ID: 21991380
PubMed ID: 23571214
Title: BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cells.
PubMed ID: 23571214
DOI: 10.1242/dev.087502
PubMed ID: 23303788
Title: Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2.
PubMed ID: 23303788
DOI: 10.1093/nar/gks1454
PubMed ID: 26522984
Title: The PIAS-like coactivator Zmiz1 is a direct and selective cofactor of Notch1 in T cell development and leukemia.
PubMed ID: 26522984
PubMed ID: 29030483
Title: RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1.
PubMed ID: 29030483
PubMed ID: 16530044
Title: Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
PubMed ID: 16530044
PubMed ID: 22883147
Title: RBPJ mutations identified in two families affected by Adams-Oliver syndrome.
PubMed ID: 22883147
Sequence Information:
- Length: 500
- Mass: 55637
- Checksum: 91E50D2DE9087EDA
- Sequence:
MDHTEGSPAE EPPAHAPSPG KFGERPPPKR LTREAMRNYL KERGDQTVLI LHAKVAQKSY GNEKRFFCPP PCVYLMGSGW KKKKEQMERD GCSEQESQPC AFIGIGNSDQ EMQQLNLEGK NYCTAKTLYI SDSDKRKHFM LSVKMFYGNS DDIGVFLSKR IKVISKPSKK KQSLKNADLC IASGTKVALF NRLRSQTVST RYLHVEGGNF HASSQQWGAF FIHLLDDDES EGEEFTVRDG YIHYGQTVKL VCSVTGMALP RLIIRKVDKQ TALLDADDPV SQLHKCAFYL KDTERMYLCL SQERIIQFQA TPCPKEPNKE MINDGASWTI ISTDKAEYTF YEGMGPVLAP VTPVPVVESL QLNGGGDVAM LELTGQNFTP NLRVWFGDVE AETMYRCGES MLCVVPDISA FREGWRWVRQ PVQVPVTLVR NDGIIYSTSL TFTYTPEPGP RPHCSAAGAI LRANSSQVPP NESNTNSEGS YTNASTNSTS VTSSTATVVS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.