Details for: RBPJ

Gene ID: 3516

Symbol: RBPJ

Ensembl ID: ENSG00000168214

Description: recombination signal binding protein for immunoglobulin kappa J region

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 610.7870
    Cell Significance Index: -95.0100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 354.1587
    Cell Significance Index: -89.8300
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 211.9444
    Cell Significance Index: -87.3100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 209.4159
    Cell Significance Index: -98.8700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 198.0150
    Cell Significance Index: -80.4500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 174.5190
    Cell Significance Index: -89.7700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 148.0875
    Cell Significance Index: -99.3700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 84.7872
    Cell Significance Index: -80.9500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 79.2364
    Cell Significance Index: -97.7000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 31.9782
    Cell Significance Index: -85.6700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 27.9444
    Cell Significance Index: -85.8300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 24.9009
    Cell Significance Index: -98.2600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 19.8850
    Cell Significance Index: -43.5200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 3.9984
    Cell Significance Index: 224.3700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.8708
    Cell Significance Index: 56.0300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.1455
    Cell Significance Index: 430.3900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.9287
    Cell Significance Index: 1741.4700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.6183
    Cell Significance Index: 321.1600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.3597
    Cell Significance Index: 47.2500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.3260
    Cell Significance Index: 182.1000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.3090
    Cell Significance Index: 235.9800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.2951
    Cell Significance Index: 33.2900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.1999
    Cell Significance Index: 430.3700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.0891
    Cell Significance Index: 20.1300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9821
    Cell Significance Index: 120.7600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9693
    Cell Significance Index: 74.3800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.9182
    Cell Significance Index: 405.9400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.8643
    Cell Significance Index: 472.0200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.8358
    Cell Significance Index: 23.9600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6376
    Cell Significance Index: 121.3400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5394
    Cell Significance Index: 373.0900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.5330
    Cell Significance Index: 32.7600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.3892
    Cell Significance Index: 18.2900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3500
    Cell Significance Index: 34.6200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.3463
    Cell Significance Index: 652.0600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3419
    Cell Significance Index: 43.8300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3418
    Cell Significance Index: 9.8500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2964
    Cell Significance Index: 15.4400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2776
    Cell Significance Index: 427.2800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2645
    Cell Significance Index: 11.9900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.2414
    Cell Significance Index: 7.0900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2183
    Cell Significance Index: 37.2700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2072
    Cell Significance Index: 382.1600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1632
    Cell Significance Index: 221.9300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1619
    Cell Significance Index: 8.5000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1357
    Cell Significance Index: 9.1300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1164
    Cell Significance Index: 73.9200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1100
    Cell Significance Index: 7.1000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0785
    Cell Significance Index: 35.6200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0582
    Cell Significance Index: 7.5200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0146
    Cell Significance Index: 0.3900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0140
    Cell Significance Index: 0.3900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0368
    Cell Significance Index: -27.2800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0379
    Cell Significance Index: -0.6500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0489
    Cell Significance Index: -35.8600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0691
    Cell Significance Index: -43.1800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0876
    Cell Significance Index: -66.2800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0897
    Cell Significance Index: -4.6600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1029
    Cell Significance Index: -10.5100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1269
    Cell Significance Index: -71.5800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1589
    Cell Significance Index: -2.6600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2066
    Cell Significance Index: -24.3600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2569
    Cell Significance Index: -54.1000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.2601
    Cell Significance Index: -17.9900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2750
    Cell Significance Index: -12.8200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2881
    Cell Significance Index: -21.4700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2899
    Cell Significance Index: -83.4300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3323
    Cell Significance Index: -48.3000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3327
    Cell Significance Index: -23.5300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4840
    Cell Significance Index: -5.7700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4842
    Cell Significance Index: -55.4800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.5473
    Cell Significance Index: -63.7900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6099
    Cell Significance Index: -63.5000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.6107
    Cell Significance Index: -69.7200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6126
    Cell Significance Index: -38.6100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.6161
    Cell Significance Index: -16.2000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.6786
    Cell Significance Index: -18.4700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.8052
    Cell Significance Index: -35.6200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.9081
    Cell Significance Index: -19.3400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.9293
    Cell Significance Index: -35.1900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.9676
    Cell Significance Index: -76.6300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.9977
    Cell Significance Index: -24.9400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -1.0159
    Cell Significance Index: -24.3700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -1.0439
    Cell Significance Index: -21.8500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1815
    Cell Significance Index: -72.4400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.2403
    Cell Significance Index: -74.4600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.4451
    Cell Significance Index: -41.2400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.5555
    Cell Significance Index: -49.8200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.7576
    Cell Significance Index: -23.9800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.7599
    Cell Significance Index: -57.6200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -1.8370
    Cell Significance Index: -14.9800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.9096
    Cell Significance Index: -60.8200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -2.0176
    Cell Significance Index: -12.1900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -2.1790
    Cell Significance Index: -76.3400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -2.2048
    Cell Significance Index: -32.5500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -2.2521
    Cell Significance Index: -60.3500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -2.2692
    Cell Significance Index: -60.7000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -2.3410
    Cell Significance Index: -25.4500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -2.3479
    Cell Significance Index: -86.1900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -2.3962
    Cell Significance Index: -61.2200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** RBPJ is a member of the Notch family of transcription factors, which are characterized by their ability to regulate cell fate decisions, proliferation, and differentiation. RBPJ is specifically involved in the recombination signal binding process, which is essential for the correct joining of immunoglobulin heavy and light chain genes in B cells. Its unique structure, consisting of an N-terminal domain and a C-terminal HD domain, allows it to interact with other Notch receptors and co-receptors, triggering the Notch signaling pathway. **Pathways and Functions** RBPJ is involved in various signaling pathways, including: 1. Notch signaling pathway: RBPJ is the primary ligand for Notch receptors, triggering the activation of downstream signaling molecules, such as RBP-J (also known as CBF1) and CBF1-RAP1. 2. Wnt signaling pathway: RBPJ can interact with Wnt proteins, influencing cell proliferation and differentiation. 3. TGF-β signaling pathway: RBPJ has been shown to regulate TGF-β signaling, affecting cell differentiation and proliferation. 4. Notch-hlh transcription pathway: RBPJ can regulate the expression of Notch-hlh target genes, influencing cell fate decisions. RBPJ's functions include: 1. B cell development and maturation: RBPJ is essential for the correct joining of immunoglobulin heavy and light chain genes, ensuring the proper development and maturation of B cells. 2. Immune tolerance: RBPJ can regulate the expression of immune suppressive genes, influencing immune tolerance and preventing autoimmune responses. 3. Tissue development: RBPJ is involved in the development of various tissues, including the heart, lungs, and skin. 4. Cancer development: RBPJ has been implicated in the development and progression of various cancers, including leukemia and lymphoma. **Clinical Significance** Dysregulation of RBPJ has been implicated in various diseases, including: 1. Immunodeficiency disorders: Mutations in RBPJ can lead to impaired B cell development and function, resulting in immunodeficiency disorders. 2. Cancer: RBPJ overexpression or aberrant signaling has been linked to cancer development and progression. 3. Autoimmune diseases: RBPJ can influence immune tolerance, and its dysregulation has been implicated in autoimmune diseases, such as rheumatoid arthritis and lupus. 4. Congenital heart defects: RBPJ has been shown to play a role in heart development, and its dysregulation can lead to congenital heart defects. In conclusion, RBPJ is a crucial transcription factor involved in the development and function of various tissues and organs, including the immune system. Its dysregulation can lead to various diseases, highlighting the importance of understanding its role in normal and pathological processes.

Genular Protein ID: 2136746154

Symbol: SUH_HUMAN

Name: Recombining binding protein suppressor of hairless

UniProtKB Accession Codes:

Q06330 B4DY22 Q5XKH9 Q6P1N3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 12 Ensembl 14 EvolutionaryTrace 1 ExpressionAtlas 1 GO 74 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 7 Pumba 1 RNAct 1 Reactome 12 RefSeq 10 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8406481

Title: Human Jk recombination signal binding protein gene (IGKJRB): comparison with its mouse homologue.

PubMed ID: 8406481

DOI: 10.1006/geno.1993.1326

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8016657

Title: Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa.

PubMed ID: 8016657

DOI: 10.1126/science.8016657

PubMed ID: 8627785

Title: The amino-terminal domains of Epstein-Barr virus nuclear proteins 3A, 3B, and 3C interact with RBPJ(kappa).

PubMed ID: 8627785

DOI: 10.1128/jvi.70.5.3068-3074.1996

PubMed ID: 10508479

Title: Antigens recognized by autologous antibody in patients with renal-cell carcinoma.

PubMed ID: 10508479

DOI: 10.1002/(sici)1097-0215(19991112)83:4<456::aid-ijc4>3.0.co;2-5

PubMed ID: 9874765

Title: CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex.

PubMed ID: 9874765

DOI: 10.1073/pnas.96.1.23

PubMed ID: 10644367

Title: A role for SKIP in EBNA2 activation of CBF1-repressed promoters.

PubMed ID: 10644367

DOI: 10.1128/jvi.74.4.1939-1947.2000

PubMed ID: 10637481

Title: Intracellular forms of human NOTCH1 interact at distinctly different levels with RBP-jkappa in human B and T cells.

PubMed ID: 10637481

DOI: 10.1038/sj.leu.2401630

PubMed ID: 12374742

Title: SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway.

PubMed ID: 12374742

DOI: 10.1093/emboj/cdf549

PubMed ID: 21102556

Title: RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.

PubMed ID: 21102556

DOI: 10.1038/emboj.2010.289

PubMed ID: 21991380

Title: A SILAC-based screen for Methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequence-specific binding protein.

PubMed ID: 21991380

DOI: 10.1371/journal.pone.0025884

PubMed ID: 23571214

Title: BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cells.

PubMed ID: 23571214

DOI: 10.1242/dev.087502

PubMed ID: 23303788

Title: Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2.

PubMed ID: 23303788

DOI: 10.1093/nar/gks1454

PubMed ID: 26522984

Title: The PIAS-like coactivator Zmiz1 is a direct and selective cofactor of Notch1 in T cell development and leukemia.

PubMed ID: 26522984

DOI: 10.1016/j.immuni.2015.10.007

PubMed ID: 29030483

Title: RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1.

PubMed ID: 29030483

DOI: 10.15252/embj.201796525

PubMed ID: 16530044

Title: Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.

PubMed ID: 16530044

DOI: 10.1016/j.cell.2005.12.037

PubMed ID: 22883147

Title: RBPJ mutations identified in two families affected by Adams-Oliver syndrome.

PubMed ID: 22883147

DOI: 10.1016/j.ajhg.2012.07.005

Sequence Information:

  • Length: 500
  • Mass: 55637
  • Checksum: 91E50D2DE9087EDA
  • Sequence:
    • MDHTEGSPAE EPPAHAPSPG KFGERPPPKR LTREAMRNYL KERGDQTVLI LHAKVAQKSY 
GNEKRFFCPP PCVYLMGSGW KKKKEQMERD GCSEQESQPC AFIGIGNSDQ EMQQLNLEGK 
NYCTAKTLYI SDSDKRKHFM LSVKMFYGNS DDIGVFLSKR IKVISKPSKK KQSLKNADLC 
IASGTKVALF NRLRSQTVST RYLHVEGGNF HASSQQWGAF FIHLLDDDES EGEEFTVRDG 
YIHYGQTVKL VCSVTGMALP RLIIRKVDKQ TALLDADDPV SQLHKCAFYL KDTERMYLCL 
SQERIIQFQA TPCPKEPNKE MINDGASWTI ISTDKAEYTF YEGMGPVLAP VTPVPVVESL 
QLNGGGDVAM LELTGQNFTP NLRVWFGDVE AETMYRCGES MLCVVPDISA FREGWRWVRQ 
PVQVPVTLVR NDGIIYSTSL TFTYTPEPGP RPHCSAAGAI LRANSSQVPP NESNTNSEGS 
YTNASTNSTS VTSSTATVVS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.