Details for: ITGA5

Gene ID: 3678

Symbol: ITGA5

Ensembl ID: ENSG00000161638

Description: integrin subunit alpha 5

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 5.34
    Marker Score: 15840
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 3.72
    Marker Score: 2982
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.54
    Marker Score: 86331
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 2.33
    Marker Score: 6692
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 2.28
    Marker Score: 1301
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 2.26
    Marker Score: 1280
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 2.2
    Marker Score: 3186
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 2.03
    Marker Score: 509
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 1.93
    Marker Score: 1820
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 1.85
    Marker Score: 4697
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 1.75
    Marker Score: 1502
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 1.74
    Marker Score: 421
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.69
    Marker Score: 2460
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.47
    Marker Score: 968
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168386
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 1.41
    Marker Score: 338
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.38
    Marker Score: 3258
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 1.38
    Marker Score: 8394
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.34
    Marker Score: 1428
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.33
    Marker Score: 338
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 1.31
    Marker Score: 1186
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 1.31
    Marker Score: 507
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.29
    Marker Score: 2571
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 1.26
    Marker Score: 293
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.22
    Marker Score: 68112
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.21
    Marker Score: 5234
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 1.21
    Marker Score: 589
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.17
    Marker Score: 269
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 1.14
    Marker Score: 492
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 1.12
    Marker Score: 1004
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.12
    Marker Score: 667
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.11
    Marker Score: 17428
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 1.08
    Marker Score: 1162.5
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 1.08
    Marker Score: 242
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 1.05
    Marker Score: 224
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251741
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.01
    Marker Score: 588
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71759
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47984
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30400
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.97
    Marker Score: 868
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.97
    Marker Score: 483
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 0.96
    Marker Score: 968.5
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2411
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.94
    Marker Score: 1594
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.92
    Marker Score: 3416
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.91
    Marker Score: 5199
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2720
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 0.91
    Marker Score: 1245
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5294
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.87
    Marker Score: 1774
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.87
    Marker Score: 22316
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.86
    Marker Score: 516
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.85
    Marker Score: 210
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: 0.84
    Marker Score: 235
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 0.83
    Marker Score: 850
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 0.83
    Marker Score: 522
  • Cell Name: trophoblast giant cell (CL0002488)
    Fold Change: 0.82
    Marker Score: 267
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 0.82
    Marker Score: 341
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: 0.82
    Marker Score: 339
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.82
    Marker Score: 510
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 0.82
    Marker Score: 212
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.81
    Marker Score: 253
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.81
    Marker Score: 4841
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.79
    Marker Score: 606
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 0.78
    Marker Score: 294
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.76
    Marker Score: 1234
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 0.76
    Marker Score: 215
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.75
    Marker Score: 688
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.75
    Marker Score: 775
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 0.75
    Marker Score: 879
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.74
    Marker Score: 381
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.73
    Marker Score: 1385
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 0.73
    Marker Score: 902
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.73
    Marker Score: 837
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 0.73
    Marker Score: 830
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.72
    Marker Score: 2374
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.72
    Marker Score: 232
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.7
    Marker Score: 674
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.68
    Marker Score: 1702
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.67
    Marker Score: 428
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 0.67
    Marker Score: 2781
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 171
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.67
    Marker Score: 146
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 0.67
    Marker Score: 277
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.66
    Marker Score: 186
  • Cell Name: peritubular capillary endothelial cell (CL1001033)
    Fold Change: 0.65
    Marker Score: 150
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 0.64
    Marker Score: 1661
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 0.64
    Marker Score: 1240
  • Cell Name: fibroblast of connective tissue of prostate (CL1000299)
    Fold Change: 0.63
    Marker Score: 156
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.62
    Marker Score: 7029
  • Cell Name: prostate stromal cell (CL0002622)
    Fold Change: 0.62
    Marker Score: 156
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.61
    Marker Score: 711
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 0.6
    Marker Score: 396
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 0.6
    Marker Score: 219
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.59
    Marker Score: 903
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 0.58
    Marker Score: 1526
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 0.58
    Marker Score: 1832
  • Cell Name: vasa recta ascending limb cell (CL1001131)
    Fold Change: 0.58
    Marker Score: 153
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.58
    Marker Score: 696

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Other Information

**Key characteristics:** - ITGA5 is a transmembrane protein with a predicted molecular weight of approximately 120 kDa. - It is a glycoprotein that is highly expressed in endothelial cells, where it is involved in cell adhesion and migration. - ITGA5 is also expressed in other cell types, where it has been implicated in cell migration, cell adhesion, and tissue remodeling. **Pathways and functions:** - ITGA5 is a key molecule in the cell adhesion cascade, which is responsible for the formation and maintenance of cell contacts with the extracellular matrix. - It is involved in the regulation of vascular endothelial cell migration and adhesion to extracellular matrix components. - ITGA5 also plays a role in cell migration, cell adhesion, and tissue remodeling. **Clinical significance:** - Mutations in ITGA5 have been linked to several human diseases, including pulmonary arterial hypertension, which is characterized by the formation of abnormal blood vessels in the lungs. - ITGA5 is also involved in the development and maintenance of the cardiovascular system, the nervous system, and the immune system. - Therefore, targeting ITGA5 could be a potential therapeutic strategy for diseases characterized by abnormal cell adhesion and migration. **Additional notes:** - ITGA5 is a highly conserved protein, with similar sequences found in mammals and other vertebrates. - It is a member of the integrin superfamily of cell adhesion molecules, which are characterized by their ability to interact with extracellular matrix proteins. - ITGA5 is a key regulator of cell migration and adhesion, and its expression is often upregulated in cancer cells.

Genular Protein ID: 2171937948

Symbol: ITA5_HUMAN

Name: CD49 antigen-like family member E

UniProtKB Accession Codes:

P08648 Q96HA5

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEBI 24 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 ELM 1 EMBL 3 EMDB 2 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 42 Gene3D 5 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 2 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 19 PDBsum 8 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 7 RefSeq 1 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2958481

Title: Amino acid sequence of the human fibronectin receptor.

PubMed ID: 2958481

DOI: 10.1083/jcb.105.3.1183

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1834647

Title: The alpha 5 beta 1 fibronectin receptor. Characterization of the alpha 5 gene promoter.

PubMed ID: 1834647

DOI: 10.1016/s0021-9258(18)54959-0

PubMed ID: 2450560

Title: Comparison of cDNA-derived protein sequences of the human fibronectin and vitronectin receptor alpha-subunits and platelet glycoprotein IIb.

PubMed ID: 2450560

DOI: 10.1021/bi00399a021

PubMed ID: 2944883

Title: cDNA sequences from the alpha subunit of the fibronectin receptor predict a transmembrane domain and a short cytoplasmic peptide.

PubMed ID: 2944883

DOI: 10.1016/s0021-9258(18)69249-x

PubMed ID: 3033641

Title: The very late antigen family of heterodimers is part of a superfamily of molecules involved in adhesion and embryogenesis.

PubMed ID: 3033641

DOI: 10.1073/pnas.84.10.3239

PubMed ID: 10397733

Title: The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor.

PubMed ID: 10397733

PubMed ID: 10094488

Title: Identification of novel interaction partners for the conserved membrane proximal region of alpha-integrin cytoplasmic domains.

PubMed ID: 10094488

DOI: 10.1016/s0014-5793(99)00151-9

PubMed ID: 11912194

Title: Insulin receptor substrate 4 associates with the protein IRAS.

PubMed ID: 11912194

DOI: 10.1074/jbc.m111838200

PubMed ID: 14596610

Title: Mass spectrometric based mapping of the disulfide bonding patterns of integrin alpha chains.

PubMed ID: 14596610

DOI: 10.1021/bi034726u

PubMed ID: 12907437

Title: Alpha5beta1 integrin as a cellular coreceptor for human parvovirus B19: requirement of functional activation of beta1 integrin for viral entry.

PubMed ID: 12907437

DOI: 10.1182/blood-2003-05-1522

PubMed ID: 12695522

Title: CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family.

PubMed ID: 12695522

DOI: 10.1074/jbc.m302028200

PubMed ID: 12807887

Title: Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins.

PubMed ID: 12807887

DOI: 10.1074/jbc.m303159200

PubMed ID: 16051604

Title: Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins.

PubMed ID: 16051604

DOI: 10.1074/jbc.m504778200

PubMed ID: 16754960

Title: Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.

PubMed ID: 16754960

DOI: 10.1083/jcb.200509019

PubMed ID: 17158881

Title: alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity.

PubMed ID: 17158881

DOI: 10.1074/jbc.m607008200

PubMed ID: 18635536

Title: Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner.

PubMed ID: 18635536

DOI: 10.1074/jbc.m804835200

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22740495

Title: Cleavage of endometrial alpha-integrins into their functional forms is mediated by proprotein convertase 5/6.

PubMed ID: 22740495

DOI: 10.1093/humrep/des203

PubMed ID: 24011356

Title: Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity.

PubMed ID: 24011356

DOI: 10.1021/bi400678y

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24478423

Title: Roles of the putative integrin-binding motif of the human metapneumovirus fusion (f) protein in cell-cell fusion, viral infectivity, and pathogenesis.

PubMed ID: 24478423

DOI: 10.1128/jvi.03491-13

PubMed ID: 25398877

Title: Proinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins alphavbeta3, alpha4beta1, and alpha5beta1.

PubMed ID: 25398877

DOI: 10.1074/jbc.m114.579946

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29030430

Title: Direct binding to integrins and loss of disulfide linkage in interleukin-1beta (IL-1beta) are involved in the agonistic action of IL-1beta.

PubMed ID: 29030430

DOI: 10.1074/jbc.m117.818302

PubMed ID: 31331973

Title: Integrin Binding to the Trimeric Interface of CD40L Plays a Critical Role in CD40/CD40L Signaling.

PubMed ID: 31331973

DOI: 10.4049/jimmunol.1801630

PubMed ID: 33102950

Title: The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection.

PubMed ID: 33102950

DOI: 10.1016/j.jacbts.2020.10.003

PubMed ID: 32908006

Title: Characterization of ANGPT2 mutations associated with primary lymphedema.

PubMed ID: 32908006

DOI: 10.1126/scitranslmed.aax8013

PubMed ID: 22451694

Title: Crystal structure of alpha5beta1 integrin ectodomain: atomic details of the fibronectin receptor.

PubMed ID: 22451694

DOI: 10.1083/jcb.201111077

PubMed ID: 33962943

Title: Structural insights into integrin alpha5beta1 opening by fibronectin ligand.

PubMed ID: 33962943

DOI: 10.1126/sciadv.abe9716

Sequence Information:

  • Length: 1049
  • Mass: 114536
  • Checksum: 6B4D558D4F739CBA
  • Sequence:
    • MGSRTPESPL HAVQLRWGPR RRPPLLPLLL LLLPPPPRVG GFNLDAEAPA VLSGPPGSFF 
GFSVEFYRPG TDGVSVLVGA PKANTSQPGV LQGGAVYLCP WGASPTQCTP IEFDSKGSRL 
LESSLSSSEG EEPVEYKSLQ WFGATVRAHG SSILACAPLY SWRTEKEPLS DPVGTCYLST 
DNFTRILEYA PCRSDFSWAA GQGYCQGGFS AEFTKTGRVV LGGPGSYFWQ GQILSATQEQ 
IAESYYPEYL INLVQGQLQT RQASSIYDDS YLGYSVAVGE FSGDDTEDFV AGVPKGNLTY 
GYVTILNGSD IRSLYNFSGE QMASYFGYAV AATDVNGDGL DDLLVGAPLL MDRTPDGRPQ 
EVGRVYVYLQ HPAGIEPTPT LTLTGHDEFG RFGSSLTPLG DLDQDGYNDV AIGAPFGGET 
QQGVVFVFPG GPGGLGSKPS QVLQPLWAAS HTPDFFGSAL RGGRDLDGNG YPDLIVGSFG 
VDKAVVYRGR PIVSASASLT IFPAMFNPEE RSCSLEGNPV ACINLSFCLN ASGKHVADSI 
GFTVELQLDW QKQKGGVRRA LFLASRQATL TQTLLIQNGA REDCREMKIY LRNESEFRDK 
LSPIHIALNF SLDPQAPVDS HGLRPALHYQ SKSRIEDKAQ ILLDCGEDNI CVPDLQLEVF 
GEQNHVYLGD KNALNLTFHA QNVGEGGAYE AELRVTAPPE AEYSGLVRHP GNFSSLSCDY 
FAVNQSRLLV CDLGNPMKAG ASLWGGLRFT VPHLRDTKKT IQFDFQILSK NLNNSQSDVV 
SFRLSVEAQA QVTLNGVSKP EAVLFPVSDW HPRDQPQKEE DLGPAVHHVY ELINQGPSSI 
SQGVLELSCP QALEGQQLLY VTRVTGLNCT TNHPINPKGL ELDPEGSLHH QQKREAPSRS 
SASSGPQILK CPEAECFRLR CELGPLHQQE SQSLQLHFRV WAKTFLQREH QPFSLQCEAV 
YKALKMPYRI LPRQLPQKER QVATAVQWTK AEGSYGVPLW IIILAILFGL LLLGLLIYIL 
YKLGFFKRSL PYGTAMEKAQ LKPPATSDA

Genular Protein ID: 238077805

Symbol: B2R627_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2R627

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 4 Gene3D 5 GenomeRNAi 1 InterPro 9 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 Pfam 7 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 1049
  • Mass: 114480
  • Checksum: 721EB10B257E1833
  • Sequence:
    • MGSRTPESPL HAVQLRWGPR RRPPLLPLLL LLLPPPPRVG GFNLDAEAPA VLSGPPGSFF 
GFSVEFYRPG TDGVSVLVGA PKANTSQPGV LQGGAVYLCP WGASPTQCTP IEFDSKGSRL 
LESSLSSSEG EEPVEYKSLQ WFGATVRAHG SSILACAPLY SWRTEKEPLS DPVGTCYLST 
DNFTRILEYA PCRSDFSWAA GQGYCQGGFS AEFTKTGRVV LGGPGSYFWQ GQILSATQEQ 
IAESYYPEYL INLVQGQLQT RQASSIYDDS YLGYSVAVGE FSGDDTEDFV AGVPKGNLTY 
GYVTILNGSD IRSLYNFSGE QMASYFGYAV AATDVNGDGL DDLLVGAPLL MDRTPDGRPQ 
GVGRVYVYLQ HPAGIEPTPT LTLTGHDEFG RFGSSLTPLG DLDQDGYNDV AIGAPFGGET 
QQGVVFVFPG GPGGLGSKLS QVLQPLWAAS HTPDFFGSAL RGGRDLDGNG YPDLIVGSFG 
VDKAVVYRGR PIVSASASLT IFPAMFNPEE RSCSLEGNPV ACINLSFCLN ASGKHVADSI 
GFTVELQLDW QKQKGGVRRA LFLASRQATL TQTLLIQNGA REDCREMKIY LRNESEFRDK 
LSPIHIALNF SLDPQAPVDS HGLRPALHYQ SKSRIEDKAQ ILLDCGEDNI CVPDLQLEVF 
GEQNHVYLGD KNALNLTFHA QNVGEGGAYE AELRVTAPPE AEYSGLVRHP GNFSSLSCDY 
FAVNQSRLLV CDLGNPMKAG ASLWGGLRFT VPHLRDTKKT IQFDFQILSK NLNNSQSDVV 
SFRLSVEAQA QVTLNGVSKP EAVLFPVSDW HPRDQPQKEE DLGPAVHHVY ELINQGPSSI 
SQGVLELSCP QALEGQQLLY VTRVTGLNCT TNHPINPKGL ELDPEGSLHH QQKREAPSRS 
SASSGPQILK CPEAECFRLR CELGPLHQQE SQSLQLHFRV WAKTFLQREH QPFSLQCEAV 
YKALKMPYRI LPRQLPQKER QVATAVQWTK AEGSYGVPLW IIILAILFGL LLLGLLIYIL 
YKLGFFKRSL PYGTAMEKAQ LKPPATSDA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.