Details for: KCNA5
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 2
Marker Score: 1996.5 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.65
Marker Score: 3344 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.61
Marker Score: 1172 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.27
Marker Score: 857 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1.18
Marker Score: 488 - Cell Name: goblet cell (CL0000160)
Fold Change: 1.16
Marker Score: 7693 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.15
Marker Score: 4818 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.14
Marker Score: 17802.5 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.14
Marker Score: 2154 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 1.1
Marker Score: 504 - Cell Name: B-2 B cell (CL0000822)
Fold Change: 1.09
Marker Score: 1341 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.09
Marker Score: 568 - Cell Name: tracheobronchial smooth muscle cell (CL0019019)
Fold Change: 1.07
Marker Score: 314 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71829.5 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48054 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.99
Marker Score: 510 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30409 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.98
Marker Score: 463 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.97
Marker Score: 693 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2412 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5351 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.94
Marker Score: 375 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2741 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.91
Marker Score: 839 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.91
Marker Score: 327 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.9
Marker Score: 1831 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5294 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.87
Marker Score: 414 - Cell Name: mast cell (CL0000097)
Fold Change: 0.83
Marker Score: 481 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.83
Marker Score: 787 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.82
Marker Score: 804 - Cell Name: muscle cell (CL0000187)
Fold Change: 0.82
Marker Score: 231 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1267 - Cell Name: brush cell (CL0002204)
Fold Change: 0.78
Marker Score: 709 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.77
Marker Score: 398 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.75
Marker Score: 574 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.73
Marker Score: 296 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.72
Marker Score: 463 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7
Marker Score: 180 - Cell Name: neutrophil (CL0000775)
Fold Change: 0.64
Marker Score: 388 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.59
Marker Score: 356 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 442 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.55
Marker Score: 175 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.5
Marker Score: 133 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.49
Marker Score: 204 - Cell Name: bronchial smooth muscle cell (CL0002598)
Fold Change: 0.46
Marker Score: 131 - Cell Name: supporting cell (CL0000630)
Fold Change: 0.45
Marker Score: 837 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.43
Marker Score: 189 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.39
Marker Score: 388 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 0.39
Marker Score: 365 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.38
Marker Score: 254.5 - Cell Name: PP cell (CL0000696)
Fold Change: 0.38
Marker Score: 85 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 0.35
Marker Score: 1244 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.35
Marker Score: 153 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.3
Marker Score: 365 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 0.29
Marker Score: 865.5 - Cell Name: endothelial cell of artery (CL1000413)
Fold Change: 0.28
Marker Score: 117 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 0.28
Marker Score: 183 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.27
Marker Score: 1127 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 0.26
Marker Score: 176 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.26
Marker Score: 249 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 0.25
Marker Score: 728 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.25
Marker Score: 580 - Cell Name: pericyte (CL0000669)
Fold Change: 0.24
Marker Score: 142 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 0.24
Marker Score: 111 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.24
Marker Score: 918 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.23
Marker Score: 65 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.22
Marker Score: 74 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.22
Marker Score: 130 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 0.19
Marker Score: 128 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.18
Marker Score: 312 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 0.18
Marker Score: 314 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 0.18
Marker Score: 58 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.18
Marker Score: 1507 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.17
Marker Score: 43 - Cell Name: plasmacytoid dendritic cell, human (CL0001058)
Fold Change: 0.17
Marker Score: 44 - Cell Name: plasmacytoid dendritic cell (CL0000784)
Fold Change: 0.17
Marker Score: 89 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 0.17
Marker Score: 53 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.16
Marker Score: 165 - Cell Name: mature B cell (CL0000785)
Fold Change: 0.16
Marker Score: 119 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 0.16
Marker Score: 218 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.16
Marker Score: 170 - Cell Name: fibrocyte (CL0000135)
Fold Change: 0.15
Marker Score: 47 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.15
Marker Score: 37 - Cell Name: neuron (CL0000540)
Fold Change: 0.14
Marker Score: 565 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 0.14
Marker Score: 48 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.14
Marker Score: 47 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.13
Marker Score: 130 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.13
Marker Score: 83 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.13
Marker Score: 72.5 - Cell Name: mesothelial cell (CL0000077)
Fold Change: 0.13
Marker Score: 51 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.12
Marker Score: 32 - Cell Name: immature B cell (CL0000816)
Fold Change: 0.12
Marker Score: 80 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.12
Marker Score: 325.5 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.12
Marker Score: 144 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 0.12
Marker Score: 140 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.11
Marker Score: 143 - Cell Name: basal cell (CL0000646)
Fold Change: 0.11
Marker Score: 147 - Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 0.11
Marker Score: 22 - Cell Name: plasma cell (CL0000786)
Fold Change: 0.11
Marker Score: 124
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Other Information
Genular Protein ID: 3994311991
Symbol: KCNA5_HUMAN
Name: Potassium voltage-gated channel subfamily A member 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2001794
Title: Molecular cloning and characterization of two voltage-gated K+ channel cDNAs from human ventricle.
PubMed ID: 2001794
PubMed ID: 1986382
Title: Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel.
PubMed ID: 1986382
DOI: 10.1073/pnas.88.1.53
PubMed ID: 1349297
Title: Molecular cloning, characterization, and genomic localization of a human potassium channel gene.
PubMed ID: 1349297
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8505626
Title: A rapidly activating and slowly inactivating potassium channel cloned from human heart. Functional analysis after stable mammalian cell culture expression.
PubMed ID: 8505626
PubMed ID: 11524461
Title: Altered state dependence of c-type inactivation in the long and short forms of human Kv1.5.
PubMed ID: 11524461
PubMed ID: 12130714
Title: Modulation of the human Kv1.5 channel by protein kinase C activation: role of the Kvbeta1.2 subunit.
PubMed ID: 12130714
PubMed ID: 16466689
Title: A specific N-terminal residue in Kv1.5 is required for upregulation of the channel by SAP97.
PubMed ID: 16466689
PubMed ID: 16772329
Title: Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation.
PubMed ID: 16772329
DOI: 10.1093/hmg/ddl143
PubMed ID: 17261810
Title: SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5.
PubMed ID: 17261810
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 24936649
Title: Novel mutations in BMPR2, ACVRL1 and KCNA5 genes and hemodynamic parameters in patients with pulmonary arterial hypertension.
PubMed ID: 24936649
Sequence Information:
- Length: 613
- Mass: 67228
- Checksum: A5B02B27F8396E3D
- Sequence:
MEIALVPLEN GGAMTVRGGD EARAGCGQAT GGELQCPPTA GLSDGPKEPA PKGRGAQRDA DSGVRPLPPL PDPGVRPLPP LPEELPRPRR PPPEDEEEEG DPGLGTVEDQ ALGTASLHHQ RVHINISGLR FETQLGTLAQ FPNTLLGDPA KRLRYFDPLR NEYFFDRNRP SFDGILYYYQ SGGRLRRPVN VSLDVFADEI RFYQLGDEAM ERFREDEGFI KEEEKPLPRN EFQRQVWLIF EYPESSGSAR AIAIVSVLVI LISIITFCLE TLPEFRDERE LLRHPPAPHQ PPAPAPGANG SGVMAPPSGP TVAPLLPRTL ADPFFIVETT CVIWFTFELL VRFFACPSKA GFSRNIMNII DVVAIFPYFI TLGTELAEQQ PGGGGGGQNG QQAMSLAILR VIRLVRVFRI FKLSRHSKGL QILGKTLQAS MRELGLLIFF LFIGVILFSS AVYFAEADNQ GTHFSSIPDA FWWAVVTMTT VGYGDMRPIT VGGKIVGSLC AIAGVLTIAL PVPVIVSNFN YFYHRETDHE EPAVLKEEQG TQSQGPGLDR GVQRKVSGSR GSFCKAGGTL ENADSARRGS CPLEKCNVKA KSNVDLRRSL YALCLDTSRE TDL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.