Details for: KIT
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 60.1754
Cell Significance Index: -9.3600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 24.3255
Cell Significance Index: -6.1700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 7.7294
Cell Significance Index: -9.5300 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 4.5510
Cell Significance Index: 45.9100 - Cell Name: epithelial cell of sweat gland (CL1000448)
Fold Change: 4.1978
Cell Significance Index: 3.0000 - Cell Name: columnar/cuboidal epithelial cell (CL0000075)
Fold Change: 4.0559
Cell Significance Index: 15.5300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.5359
Cell Significance Index: -5.5500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 2.4556
Cell Significance Index: -9.6900 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 2.3442
Cell Significance Index: -7.2000 - Cell Name: germ cell (CL0000586)
Fold Change: 2.2064
Cell Significance Index: 16.6600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 2.0769
Cell Significance Index: 205.4500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 1.9537
Cell Significance Index: 91.8200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.7625
Cell Significance Index: 50.3000 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 1.7137
Cell Significance Index: 10.9400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.4981
Cell Significance Index: 20.4400 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.4597
Cell Significance Index: 187.1300 - Cell Name: keratocyte (CL0002363)
Fold Change: 1.3281
Cell Significance Index: 21.0700 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 1.3195
Cell Significance Index: 14.0200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.0928
Cell Significance Index: 177.7300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.0116
Cell Significance Index: 110.0400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.8539
Cell Significance Index: 18.1900 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 0.7634
Cell Significance Index: 9.9000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.6009
Cell Significance Index: 16.0800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.5809
Cell Significance Index: 40.1800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.5673
Cell Significance Index: 392.3600 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.5290
Cell Significance Index: 7.5300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5159
Cell Significance Index: 30.9700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.5149
Cell Significance Index: 327.0100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.4853
Cell Significance Index: 25.2100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.4181
Cell Significance Index: 25.7000 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.3855
Cell Significance Index: 49.8000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2982
Cell Significance Index: 7.4600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.2614
Cell Significance Index: 12.1900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2376
Cell Significance Index: 85.2100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2220
Cell Significance Index: 42.2500 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.2088
Cell Significance Index: 3.2300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.1953
Cell Significance Index: 1.1800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.1439
Cell Significance Index: 3.4500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0632
Cell Significance Index: 3.5500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0560
Cell Significance Index: 34.9400 - Cell Name: diffuse bipolar 1 cell (CL4033027)
Fold Change: 0.0540
Cell Significance Index: 0.6600 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0492
Cell Significance Index: 0.7100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0421
Cell Significance Index: 64.8100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0185
Cell Significance Index: 3.3400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0182
Cell Significance Index: 33.5800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.0180
Cell Significance Index: 2.0500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0157
Cell Significance Index: 3.1200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0051
Cell Significance Index: 2.2500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0028
Cell Significance Index: 5.2500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0022
Cell Significance Index: -1.6100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0029
Cell Significance Index: -1.6400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0035
Cell Significance Index: -0.0700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0063
Cell Significance Index: -8.6200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0065
Cell Significance Index: -0.2300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0082
Cell Significance Index: -0.2300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0093
Cell Significance Index: -1.8700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0114
Cell Significance Index: -8.6000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0119
Cell Significance Index: -1.3900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0127
Cell Significance Index: -2.6800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0132
Cell Significance Index: -9.6800 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0134
Cell Significance Index: -0.2900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0148
Cell Significance Index: -0.6700 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0164
Cell Significance Index: -8.9300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0169
Cell Significance Index: -7.6700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0187
Cell Significance Index: -0.5400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0210
Cell Significance Index: -0.4600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0276
Cell Significance Index: -7.9500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0303
Cell Significance Index: -5.1700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0355
Cell Significance Index: -4.3700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0373
Cell Significance Index: -5.1200 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: -0.0383
Cell Significance Index: -0.3700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0523
Cell Significance Index: -7.6000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0594
Cell Significance Index: -6.0700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0619
Cell Significance Index: -4.3800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0631
Cell Significance Index: -7.2300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0847
Cell Significance Index: -8.8200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0878
Cell Significance Index: -1.4700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0923
Cell Significance Index: -10.8900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1009
Cell Significance Index: -7.5200 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.1070
Cell Significance Index: -1.2800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1095
Cell Significance Index: -7.3600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1175
Cell Significance Index: -9.0200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1202
Cell Significance Index: -3.8500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1283
Cell Significance Index: -10.1600 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -0.1437
Cell Significance Index: -1.8500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1572
Cell Significance Index: -9.6400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1724
Cell Significance Index: -11.1200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1729
Cell Significance Index: -10.9000 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.1765
Cell Significance Index: -1.6300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1768
Cell Significance Index: -5.6300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1830
Cell Significance Index: -4.9800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1876
Cell Significance Index: -9.8500 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.1885
Cell Significance Index: -3.7100 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2070
Cell Significance Index: -3.1200 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.2156
Cell Significance Index: -3.0900 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.2212
Cell Significance Index: -9.6200 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -0.2254
Cell Significance Index: -4.7000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2311
Cell Significance Index: -10.2200 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2364
Cell Significance Index: -7.7400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.2435
Cell Significance Index: -8.4600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4039253018
Symbol: KIT_HUMAN
Name: Mast/stem cell growth factor receptor Kit
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2448137
Title: Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.
PubMed ID: 2448137
PubMed ID: 1279499
Title: Organization and nucleotide sequence of the human KIT (mast/stem cell growth factor receptor) proto-oncogene.
PubMed ID: 1279499
PubMed ID: 7505199
Title: Complementary DNA cloning and characterization of truncated form of c-kit in human colon carcinoma cells.
PubMed ID: 7505199
PubMed ID: 9027509
Title: Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes.
PubMed ID: 9027509
PubMed ID: 15039213
Title: Expression of a truncated form of the c-Kit tyrosine kinase receptor and activation of Src kinase in human prostatic cancer.
PubMed ID: 15039213
PubMed ID: 20658618
Title: Retinoic acid enhances sensitivity of neuroblastoma cells for imatinib mesylate.
PubMed ID: 20658618
DOI: 10.1002/pbc.22603
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18593464
Title: Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.
PubMed ID: 18593464
DOI: 10.1186/ar2447
PubMed ID: 7506248
Title: Characterization of the promoter region of the human c-kit proto-oncogene.
PubMed ID: 7506248
PubMed ID: 7520444
Title: Modulation of Kit/stem cell factor receptor-induced signaling by protein kinase C.
PubMed ID: 7520444
PubMed ID: 7539802
Title: Identification of the major phosphorylation sites for protein kinase C in kit/stem cell factor receptor in vitro and in intact cells.
PubMed ID: 7539802
PubMed ID: 9038210
Title: Direct association of Csk homologous kinase (CHK) with the diphosphorylated site Tyr568/570 of the activated c-KIT in megakaryocytes.
PubMed ID: 9038210
PubMed ID: 9341198
Title: Lyn associates with the juxtamembrane region of c-Kit and is activated by stem cell factor in hematopoietic cell lines and normal progenitor cells.
PubMed ID: 9341198
PubMed ID: 9528781
Title: SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain.
PubMed ID: 9528781
PubMed ID: 10377264
Title: Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor.
PubMed ID: 10377264
DOI: 10.1042/bj3410211
PubMed ID: 10397721
Title: The receptor protein tyrosine phosphatase, PTP-RO, is upregulated during megakaryocyte differentiation and is associated with the c-Kit receptor.
PubMed ID: 10397721
PubMed ID: 11018522
Title: The direct association of the multiple PDZ domain containing proteins (MUPP-1) with the human c-Kit C-terminus is regulated by tyrosine kinase activity.
PubMed ID: 11018522
PubMed ID: 11825908
Title: Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling.
PubMed ID: 11825908
PubMed ID: 12444928
Title: The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit.
PubMed ID: 12444928
DOI: 10.1042/bj20020716
PubMed ID: 12878163
Title: Identification of Tyr900 in the kinase domain of c-Kit as a Src-dependent phosphorylation site mediating interaction with c-Crk.
PubMed ID: 12878163
PubMed ID: 12511554
Title: Src family kinases are involved in the differential signaling from two splice forms of c-Kit.
PubMed ID: 12511554
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 17595334
Title: The tyrosine kinase FES is an essential effector of KITD816V proliferation signal.
PubMed ID: 17595334
PubMed ID: 17904548
Title: Grb2 mediates negative regulation of stem cell factor receptor/c-Kit signaling by recruitment of Cbl.
PubMed ID: 17904548
PubMed ID: 19265199
Title: The D816V mutation of c-Kit circumvents a requirement for Src family kinases in c-Kit signal transduction.
PubMed ID: 19265199
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 20601678
Title: Expression of a truncated form of KIT tyrosine kinase in human spermatozoa correlates with sperm DNA integrity.
PubMed ID: 20601678
PubMed ID: 20147452
Title: Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance.
PubMed ID: 20147452
DOI: 10.1093/jb/mvq015
PubMed ID: 21640708
Title: Mechanism of activation of human c-KIT kinase by internal tandem duplications of the juxtamembrane domain and point mutations at aspartic acid 816.
PubMed ID: 21640708
PubMed ID: 21135090
Title: Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells.
PubMed ID: 21135090
PubMed ID: 15526160
Title: Signal transduction via the stem cell factor receptor/c-Kit.
PubMed ID: 15526160
PubMed ID: 16129412
Title: Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor.
PubMed ID: 16129412
PubMed ID: 15625120
Title: Normal and oncogenic forms of the receptor tyrosine kinase kit.
PubMed ID: 15625120
PubMed ID: 18381929
Title: Regulation of hematopoietic stem cells by the steel factor/KIT signaling pathway.
PubMed ID: 18381929
PubMed ID: 21057534
Title: Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors.
PubMed ID: 21057534
DOI: 10.1038/onc.2010.494
PubMed ID: 12824176
Title: Structure of a c-kit product complex reveals the basis for kinase transactivation.
PubMed ID: 12824176
PubMed ID: 15123710
Title: Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase.
PubMed ID: 15123710
PubMed ID: 17662946
Title: Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor.
PubMed ID: 17662946
PubMed ID: 19164557
Title: KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients.
PubMed ID: 19164557
PubMed ID: 21030588
Title: Structural basis for c-KIT inhibition by the suppressor of cytokine signaling 6 (SOCS6) ubiquitin ligase.
PubMed ID: 21030588
PubMed ID: 1376329
Title: Human piebald trait resulting from a dominant negative mutant allele of the c-kit membrane receptor gene.
PubMed ID: 1376329
DOI: 10.1172/jci115772
PubMed ID: 1370874
Title: Dominant negative and loss of function mutations of the c-kit (mast/stem cell growth factor receptor) proto-oncogene in human piebaldism.
PubMed ID: 1370874
PubMed ID: 1717985
Title: Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism.
PubMed ID: 1717985
PubMed ID: 7691885
Title: Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product.
PubMed ID: 7691885
DOI: 10.1172/jci116761
PubMed ID: 7687267
Title: Novel mutations of the KIT (mast/stem cell growth factor receptor) proto-oncogene in human piebaldism.
PubMed ID: 7687267
PubMed ID: 8680409
Title: A 12-bp deletion (7818del12) in the c-kit protooncogene in a large Italian kindred with piebaldism.
PubMed ID: 8680409
PubMed ID: 9029028
Title: A new c-kit mutation in a case of aggressive mast cell disease.
PubMed ID: 9029028
PubMed ID: 9450866
Title: Piebaldism with deafness: molecular evidence for an expanded syndrome.
PubMed ID: 9450866
DOI: 10.1002/(sici)1096-8628(19980106)75:1<101::aid-ajmg20>3.0.co;2-p
PubMed ID: 9657776
Title: c-kit activating mutations and mast cell proliferation in human leukemia.
PubMed ID: 9657776
PubMed ID: 9699740
Title: A novel KIT gene missense mutation in a Japanese family with piebaldism.
PubMed ID: 9699740
PubMed ID: 9697690
Title: Familial gastrointestinal stromal tumours with germline mutation of the KIT gene.
PubMed ID: 9697690
DOI: 10.1038/1209
PubMed ID: 9438854
Title: Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.
PubMed ID: 9438854
PubMed ID: 10362788
Title: Activating c-kit gene mutations in human germ cell tumors.
PubMed ID: 10362788
PubMed ID: 9990072
Title: Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis.
PubMed ID: 9990072
PubMed ID: 11074500
Title: Three novel mutations of the proto-oncogene KIT cause human piebaldism.
PubMed ID: 11074500
DOI: 10.1002/1096-8628(20001106)95:1<79::aid-ajmg16>3.0.co;2-4
PubMed ID: 11505412
Title: Germline mutation in the juxtamembrane domain of the kit gene in a family with gastrointestinal stromal tumors and urticaria pigmentosa.
PubMed ID: 11505412
DOI: 10.1002/1097-0142(20010801)92:3<657::aid-cncr1367>3.0.co;2-d
PubMed ID: 15173254
Title: A germline mutation in KIT in familial diffuse cutaneous mastocytosis.
PubMed ID: 15173254
PubMed ID: 15824741
Title: A mutation-created novel intra-exonic pre-mRNA splice site causes constitutive activation of KIT in human gastrointestinal stromal tumors.
PubMed ID: 15824741
PubMed ID: 16175573
Title: Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults.
PubMed ID: 16175573
DOI: 10.1002/gcc.20265
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
PubMed ID: 19865100
Title: Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations.
PubMed ID: 19865100
DOI: 10.1038/jid.2009.281
PubMed ID: 21689725
Title: Novel, activating KIT-N822I mutation in familial cutaneous mastocytosis.
PubMed ID: 21689725
PubMed ID: 24289326
Title: A new germline mutation in KIT associated with diffuse cutaneous mastocytosis in a Chinese family.
PubMed ID: 24289326
DOI: 10.1111/ced.12225
Sequence Information:
- Length: 976
- Mass: 109865
- Checksum: 81B0CD76817F3454
- Sequence:
MRGARGAWDF LCVLLLLLRV QTGSSQPSVS PGEPSPPSIH PGKSDLIVRV GDEIRLLCTD PGFVKWTFEI LDETNENKQN EWITEKAEAT NTGKYTCTNK HGLSNSIYVF VRDPAKLFLV DRSLYGKEDN DTLVRCPLTD PEVTNYSLKG CQGKPLPKDL RFIPDPKAGI MIKSVKRAYH RLCLHCSVDQ EGKSVLSEKF ILKVRPAFKA VPVVSVSKAS YLLREGEEFT VTCTIKDVSS SVYSTWKREN SQTKLQEKYN SWHHGDFNYE RQATLTISSA RVNDSGVFMC YANNTFGSAN VTTTLEVVDK GFINIFPMIN TTVFVNDGEN VDLIVEYEAF PKPEHQQWIY MNRTFTDKWE DYPKSENESN IRYVSELHLT RLKGTEGGTY TFLVSNSDVN AAIAFNVYVN TKPEILTYDR LVNGMLQCVA AGFPEPTIDW YFCPGTEQRC SASVLPVDVQ TLNSSGPPFG KLVVQSSIDS SAFKHNGTVE CKAYNDVGKT SAYFNFAFKG NNKEQIHPHT LFTPLLIGFV IVAGMMCIIV MILTYKYLQK PMYEVQWKVV EEINGNNYVY IDPTQLPYDH KWEFPRNRLS FGKTLGAGAF GKVVEATAYG LIKSDAAMTV AVKMLKPSAH LTEREALMSE LKVLSYLGNH MNIVNLLGAC TIGGPTLVIT EYCCYGDLLN FLRRKRDSFI CSKQEDHAEA ALYKNLLHSK ESSCSDSTNE YMDMKPGVSY VVPTKADKRR SVRIGSYIER DVTPAIMEDD ELALDLEDLL SFSYQVAKGM AFLASKNCIH RDLAARNILL THGRITKICD FGLARDIKND SNYVVKGNAR LPVKWMAPES IFNCVYTFES DVWSYGIFLW ELFSLGSSPY PGMPVDSKFY KMIKEGFRML SPEHAPAEMY DIMKTCWDAD PLKRPTFKQI VQLIEKQISE STNHIYSNLA NCSPNRQKPV VDHSVRINSV GSTASSSQPL LVHDDV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.