Details for: KLC1

Gene ID: 3831

Symbol: KLC1

Ensembl ID: ENSG00000126214

Description: kinesin light chain 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 392.5868
    Cell Significance Index: -61.0700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 241.0274
    Cell Significance Index: -61.1400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 123.2942
    Cell Significance Index: -58.2100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 107.0793
    Cell Significance Index: -55.0800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 86.8526
    Cell Significance Index: -58.2800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 50.9467
    Cell Significance Index: -62.8200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 21.8105
    Cell Significance Index: -66.9900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 19.4859
    Cell Significance Index: -52.2000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 16.0439
    Cell Significance Index: -63.3100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 14.6761
    Cell Significance Index: -32.1200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 5.8235
    Cell Significance Index: 1675.6000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 4.0793
    Cell Significance Index: 214.1800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.4074
    Cell Significance Index: 482.9200
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.3881
    Cell Significance Index: 29.6200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.1654
    Cell Significance Index: 776.6800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.6595
    Cell Significance Index: 93.1200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.4686
    Cell Significance Index: 112.7000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.4330
    Cell Significance Index: 1293.9000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.3902
    Cell Significance Index: 85.4500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.0778
    Cell Significance Index: 23.0400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.0423
    Cell Significance Index: 65.6900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.9861
    Cell Significance Index: 28.1400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.9405
    Cell Significance Index: 169.5500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8574
    Cell Significance Index: 139.4500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.8168
    Cell Significance Index: 19.5900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7920
    Cell Significance Index: 97.3800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.7044
    Cell Significance Index: 9.6100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.6846
    Cell Significance Index: 46.0300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6387
    Cell Significance Index: 126.7600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6112
    Cell Significance Index: 17.0800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.6088
    Cell Significance Index: 13.1900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5773
    Cell Significance Index: 79.2800
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.5047
    Cell Significance Index: 3.8900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4748
    Cell Significance Index: 13.6800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4571
    Cell Significance Index: 20.7200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.4483
    Cell Significance Index: 19.8300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4223
    Cell Significance Index: 15.9900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3693
    Cell Significance Index: 36.5300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3647
    Cell Significance Index: 69.4100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3346
    Cell Significance Index: 42.9000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3104
    Cell Significance Index: 169.5300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.2986
    Cell Significance Index: 3.5600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2651
    Cell Significance Index: 117.2200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2650
    Cell Significance Index: 15.9100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2377
    Cell Significance Index: 16.4400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2250
    Cell Significance Index: 14.5200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2236
    Cell Significance Index: 6.4100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2144
    Cell Significance Index: 11.1400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1644
    Cell Significance Index: 3.6000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1511
    Cell Significance Index: 5.3100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1488
    Cell Significance Index: 4.0500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1192
    Cell Significance Index: 5.6000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1121
    Cell Significance Index: 13.2200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1083
    Cell Significance Index: 203.8600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 0.0749
    Cell Significance Index: 0.7800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0621
    Cell Significance Index: 8.0200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0577
    Cell Significance Index: 88.7800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0547
    Cell Significance Index: 2.5500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0383
    Cell Significance Index: 52.1100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0346
    Cell Significance Index: 22.0000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0323
    Cell Significance Index: 59.5900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0287
    Cell Significance Index: 4.9000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0146
    Cell Significance Index: 0.2500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0064
    Cell Significance Index: 0.1700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0021
    Cell Significance Index: 0.9500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0192
    Cell Significance Index: -11.9900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0204
    Cell Significance Index: -15.0900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0542
    Cell Significance Index: -39.7600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0551
    Cell Significance Index: -41.6800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0690
    Cell Significance Index: -38.9300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1446
    Cell Significance Index: -10.7800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1606
    Cell Significance Index: -5.5800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1646
    Cell Significance Index: -34.6600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1807
    Cell Significance Index: -18.4600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1954
    Cell Significance Index: -28.4100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2766
    Cell Significance Index: -32.2300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2844
    Cell Significance Index: -7.3100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2937
    Cell Significance Index: -4.9200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3468
    Cell Significance Index: -39.7300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4370
    Cell Significance Index: -49.8800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.5069
    Cell Significance Index: -12.6700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5171
    Cell Significance Index: -53.8400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.5333
    Cell Significance Index: -37.7200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6045
    Cell Significance Index: -19.3600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6585
    Cell Significance Index: -52.1500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.7082
    Cell Significance Index: -14.6900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7567
    Cell Significance Index: -46.3900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.7961
    Cell Significance Index: -4.8100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.7992
    Cell Significance Index: -11.5000
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.8489
    Cell Significance Index: -10.5900
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.8904
    Cell Significance Index: -15.4000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.8991
    Cell Significance Index: -29.4400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.9429
    Cell Significance Index: -30.0300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.9614
    Cell Significance Index: -19.0100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -1.0163
    Cell Significance Index: -23.4800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.0487
    Cell Significance Index: -30.8000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.0667
    Cell Significance Index: -22.6400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.0774
    Cell Significance Index: -21.6300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -1.1305
    Cell Significance Index: -24.4300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.1362
    Cell Significance Index: -30.4500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Motor protein function**: KLC1 is a light chain of the kinesin motor protein, which is responsible for transporting cargo along microtubules. 2. **Retrograde transport**: KLC1 is specifically involved in retrograde transport within the Golgi apparatus, a process that is essential for the movement of proteins and lipids from the Golgi to the endoplasmic reticulum. 3. **Regulation of signaling pathways**: KLC1 is implicated in the regulation of signaling pathways mediated by Rho GTPases, which are involved in various cellular processes, including cell migration, adhesion, and proliferation. 4. **Expression in multiple cell types**: KLC1 is expressed in various cell types, including neurons, astrocytes, immune cells, and vascular cells, highlighting its potential involvement in multiple physiological and pathological processes. **Pathways and Functions** 1. **Adaptive immune system**: KLC1 is involved in the regulation of immune responses, particularly in the presentation of MHC class II antigens by antigen-presenting cells. 2. **Cell adhesion**: KLC1 regulates cell adhesion by modulating the activity of Rho GTPases, which are involved in the regulation of the cytoskeleton and cell migration. 3. **Cytoskeletal motor activity**: KLC1 is involved in the regulation of cytoskeletal motor activity, which is essential for various cellular processes, including cell migration, division, and intracellular trafficking. 4. **Golgi-to-ER retrograde transport**: KLC1 is specifically involved in retrograde transport within the Golgi apparatus, a process that is essential for the movement of proteins and lipids from the Golgi to the endoplasmic reticulum. **Clinical Significance** 1. **Neurological disorders**: Alterations in KLC1 expression have been implicated in various neurological disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. 2. **Immune system dysregulation**: KLC1 is involved in the regulation of immune responses, and alterations in its expression may contribute to immune system dysregulation, as seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. 3. **Cancer**: KLC1 is implicated in the regulation of signaling pathways that are involved in cancer progression, including cell proliferation, migration, and invasion. 4. **Vascular disorders**: KLC1 is expressed in vascular cells, and alterations in its expression may contribute to vascular disorders, including atherosclerosis and stroke. In conclusion, KLC1 is a gene that plays a critical role in various cellular processes, including vesicle-mediated transport, cell adhesion, and signaling pathways. Its expression in multiple cell types highlights its potential involvement in multiple physiological and pathological processes, including neurological disorders, immune system dysregulation, cancer, and vascular disorders. Further research is needed to fully elucidate the functions of KLC1 and its role in human disease.

Genular Protein ID: 1984237713

Symbol: KLC1_HUMAN

Name: Kinesin light chain 1

UniProtKB Accession Codes:

Q07866 A6NF62 F8VTM4 Q7RTM2 Q7RTM3 Q7RTM5 Q7RTP9 Q7RTQ3 Q7RTQ5 Q7RTQ6 Q86SF5 Q86TF5 Q86V74 Q86V75 Q86V76 Q86V77 Q86V78 Q86V79 Q96H62

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 7 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 ELM 1 EMBL 36 Ensembl 10 EvolutionaryTrace 1 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 10 Pumba 1 RNAct 1 Reactome 5 RefSeq 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8274221

Title: Cloning and genetic characterization of the human kinesin light-chain (KLC) gene.

PubMed ID: 8274221

DOI: 10.1089/dna.1993.12.881

PubMed ID: 12839500

Title: Alternatively spliced products of the human kinesin light chain 1 (KNS2) gene.

PubMed ID: 12839500

DOI: 10.1034/j.1600-0854.2003.00113.x

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14970196

Title: The early onset dystonia protein torsinA interacts with kinesin light chain 1.

PubMed ID: 14970196

DOI: 10.1074/jbc.m401332200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20074060

Title: Cell-wide analysis of secretory granule dynamics in three dimensions in living pancreatic beta-cells: evidence against a role for AMPK-dependent phosphorylation of KLC1 at Ser517/Ser520 in glucose-stimulated insulin granule movement.

PubMed ID: 20074060

DOI: 10.1042/bst0380205

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21925109

Title: Kinesin-1-mediated capsid disassembly and disruption of the nuclear pore complex promote virus infection.

PubMed ID: 21925109

DOI: 10.1016/j.chom.2011.08.010

PubMed ID: 21385839

Title: Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1.

PubMed ID: 21385839

DOI: 10.1242/jcs.075168

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25898167

Title: BORC, a multisubunit complex that regulates lysosome positioning.

PubMed ID: 25898167

DOI: 10.1016/j.devcel.2015.02.011

Sequence Information:

  • Length: 573
  • Mass: 65310
  • Checksum: A66E3915C57C2764
  • Sequence:
    • MYDNMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD 
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL 
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF 
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL 
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL 
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY 
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD 
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF 
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE 
EVSMSVEWNG GVSGRASFCG KRQQQQWPGR RHR

Genular Protein ID: 300703577

Symbol: Q7RTQ2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7RTQ2

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 2 SMART 1 SUPFAM 1

Citations:

PubMed ID: 12839500

Title: Alternatively spliced products of the human kinesin light chain 1 (KNS2) gene.

PubMed ID: 12839500

Sequence Information:

  • Length: 609
  • Mass: 68762
  • Checksum: CC42D0ADB681B8C7
  • Sequence:
    • MYDTMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD 
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL 
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF 
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL 
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL 
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY 
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD 
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF 
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE 
EDGTGSLKRS GSFSKLRASI RRSSEKLVRK LKGGSSRESE PKNPGASLAE PLFVENDSSS 
SGLEDATAN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.