Details for: ARL1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 262.8175
Cell Significance Index: -40.8800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 156.7949
Cell Significance Index: -39.7700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 104.0424
Cell Significance Index: -42.8600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 96.2462
Cell Significance Index: -45.4400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 88.6631
Cell Significance Index: -36.0200 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 67.8517
Cell Significance Index: -45.5300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 37.9788
Cell Significance Index: -36.2600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 35.3054
Cell Significance Index: -43.5300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 14.0993
Cell Significance Index: -37.7700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 11.2112
Cell Significance Index: -44.2400 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 9.9236
Cell Significance Index: -30.4800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.7884
Cell Significance Index: 130.0100 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 2.4109
Cell Significance Index: 144.7400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.2231
Cell Significance Index: 60.5100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.4848
Cell Significance Index: 77.1300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.4718
Cell Significance Index: 1328.8900 - Cell Name: peg cell (CL4033014)
Fold Change: 1.4587
Cell Significance Index: 33.7000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.4388
Cell Significance Index: 197.5900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.3699
Cell Significance Index: 12.6200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.3269
Cell Significance Index: 239.2000 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 1.1624
Cell Significance Index: 12.3500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 1.1560
Cell Significance Index: 54.3300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.1415
Cell Significance Index: 140.3600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.1334
Cell Significance Index: 618.9500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.0378
Cell Significance Index: 77.3500 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.0070
Cell Significance Index: 8.0400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.8753
Cell Significance Index: 25.0900 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.8734
Cell Significance Index: 111.9700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8412
Cell Significance Index: 136.8100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.8331
Cell Significance Index: 52.5100 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.7484
Cell Significance Index: 9.5900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.7475
Cell Significance Index: 51.7000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.7319
Cell Significance Index: 323.6100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.7009
Cell Significance Index: 18.7800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.6214
Cell Significance Index: 123.3200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.6090
Cell Significance Index: 43.0700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.6062
Cell Significance Index: 27.4800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.5924
Cell Significance Index: 12.4000 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.5864
Cell Significance Index: 117.6400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.5705
Cell Significance Index: 12.3600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.5591
Cell Significance Index: 14.9300 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.5472
Cell Significance Index: 70.7000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.5070
Cell Significance Index: 86.5800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.4789
Cell Significance Index: 16.6400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3106
Cell Significance Index: 8.9500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2846
Cell Significance Index: 102.0700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.1843
Cell Significance Index: 21.7300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1490
Cell Significance Index: 14.7400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.1480
Cell Significance Index: 7.7100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1335
Cell Significance Index: 25.4100 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.1129
Cell Significance Index: 2.9700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0962
Cell Significance Index: 5.0500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0700
Cell Significance Index: 52.9900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0566
Cell Significance Index: 39.1500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0553
Cell Significance Index: 0.9300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0509
Cell Significance Index: 37.3100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0138
Cell Significance Index: 25.9700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0035
Cell Significance Index: -2.6000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0198
Cell Significance Index: -36.4300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0241
Cell Significance Index: -37.0700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0251
Cell Significance Index: -15.9700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0318
Cell Significance Index: -43.1800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0338
Cell Significance Index: -21.1100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0372
Cell Significance Index: -7.8300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0383
Cell Significance Index: -3.9100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0458
Cell Significance Index: -0.9800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0477
Cell Significance Index: -26.9200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0608
Cell Significance Index: -27.6000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0803
Cell Significance Index: -5.1800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0976
Cell Significance Index: -28.0700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1039
Cell Significance Index: -11.9000 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.1438
Cell Significance Index: -0.8800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1537
Cell Significance Index: -9.4500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1802
Cell Significance Index: -5.7700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1915
Cell Significance Index: -22.3100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1930
Cell Significance Index: -28.0600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.2612
Cell Significance Index: -7.6700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2847
Cell Significance Index: -3.8900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3149
Cell Significance Index: -21.1800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.3168
Cell Significance Index: -24.3100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.3242
Cell Significance Index: -9.0600 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.3367
Cell Significance Index: -5.0500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3527
Cell Significance Index: -19.7900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3737
Cell Significance Index: -29.6000 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3938
Cell Significance Index: -44.9500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.4061
Cell Significance Index: -42.2800 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.4630
Cell Significance Index: -5.2600 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.5062
Cell Significance Index: -25.5800 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.5941
Cell Significance Index: -17.5000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5999
Cell Significance Index: -36.7800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.6122
Cell Significance Index: -27.0800 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.6345
Cell Significance Index: -16.2100 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.6851
Cell Significance Index: -7.0900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.7089
Cell Significance Index: -17.7200 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.7214
Cell Significance Index: -14.0800 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.7448
Cell Significance Index: -7.7100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.7467
Cell Significance Index: -19.9800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.7590
Cell Significance Index: -28.7400 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.8129
Cell Significance Index: -9.6900 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.8199
Cell Significance Index: -13.7900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 608855532
Symbol: ARL1_HUMAN
Name: ADP-ribosylation factor-like protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7814376
Title: Different ARF domains are required for the activation of cholera toxin and phospholipase D.
PubMed ID: 7814376
DOI: 10.1074/jbc.270.1.21
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9624189
Title: Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1).
PubMed ID: 9624189
PubMed ID: 11303027
Title: ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins.
PubMed ID: 11303027
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21239483
Title: Arfaptins are localized to the trans-Golgi by interaction with Arl1, but not Arfs.
PubMed ID: 21239483
PubMed ID: 22981988
Title: The BAR domain protein Arfaptin-1 controls secretory granule biogenesis at the trans-Golgi network.
PubMed ID: 22981988
PubMed ID: 25255805
Title: Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.
PubMed ID: 25255805
DOI: 10.1038/ncomms5919
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 14580338
Title: Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus.
PubMed ID: 14580338
PubMed ID: 27436755
Title: Structural basis for targeting BIG1 to Golgi apparatus through interaction of its DCB domain with Arl1.
PubMed ID: 27436755
DOI: 10.1093/jmcb/mjw033
PubMed ID: 22679020
Title: Structural basis for membrane binding specificity of the Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin-2 determined by Arl1 GTPase.
PubMed ID: 22679020
PubMed ID: 27373159
Title: Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi.
PubMed ID: 27373159
Sequence Information:
- Length: 181
- Mass: 20418
- Checksum: 9FB736C8ED60DC3D
- Sequence:
MGGFFSSIFS SLFGTREMRI LILGLDGAGK TTILYRLQVG EVVTTIPTIG FNVETVTYKN LKFQVWDLGG QTSIRPYWRC YYSNTDAVIY VVDSCDRDRI GISKSELVAM LEEEELRKAI LVVFANKQDM EQAMTSSEMA NSLGLPALKD RKWQIFKTSA TKGTGLDEAM EWLVETLKSR Q
Genular Protein ID: 240668589
Symbol: B4DZG7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 135
- Mass: 15443
- Checksum: 072FA0F481008BB8
- Sequence:
MAIGFNVETV TYKNLKFQVW DLGGQTSIRP YWRCYYSNTD AVIYVVDSCD RDRIGISKSE LVAMLEEEEL RKAILVVFAN KQDMEQAMTS SEMANSLGLP ALKDRKWQIF KTSATKGTGL DEAMEWLVET LKSRQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.