Details for: MEF2A

Gene ID: 4205

Symbol: MEF2A

Ensembl ID: ENSG00000068305

Description: myocyte enhancer factor 2A

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 6.41
    Marker Score: 2,317
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 4.28
    Marker Score: 95,554
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 3.73
    Marker Score: 1,852
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 3.09
    Marker Score: 1,716
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 3
    Marker Score: 5,472
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.92
    Marker Score: 25,650
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 2.82
    Marker Score: 2,174
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 2.82
    Marker Score: 15,135
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 2.82
    Marker Score: 10,014
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.81
    Marker Score: 6,165
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.77
    Marker Score: 9,082
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.77
    Marker Score: 11,597
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.73
    Marker Score: 48,398
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.7
    Marker Score: 3,631
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.7
    Marker Score: 1,610
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.68
    Marker Score: 5,164
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.66
    Marker Score: 3,313
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.59
    Marker Score: 3,766
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.55
    Marker Score: 86,252
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 2.52
    Marker Score: 1,330
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 2.49
    Marker Score: 10,385
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.39
    Marker Score: 2,887
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.38
    Marker Score: 10,999
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2.36
    Marker Score: 2,517
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.36
    Marker Score: 2,247
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.3
    Marker Score: 45,703
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.28
    Marker Score: 719
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.28
    Marker Score: 86,413
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 2.25
    Marker Score: 2,425
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.24
    Marker Score: 82,625
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.24
    Marker Score: 9,283
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 2.22
    Marker Score: 1,669
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.21
    Marker Score: 2,546
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.19
    Marker Score: 46,813
  • Cell Name: germ cell (CL0000586)
    Fold Change: 2.19
    Marker Score: 3,828
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.19
    Marker Score: 5,477
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 2.17
    Marker Score: 946
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.16
    Marker Score: 2,382
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 2.14
    Marker Score: 1,160
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.13
    Marker Score: 16,364
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.11
    Marker Score: 2,388
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.08
    Marker Score: 609
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.08
    Marker Score: 1,841
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 2.07
    Marker Score: 1,790
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.06
    Marker Score: 1,198
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 2.04
    Marker Score: 739
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 2.02
    Marker Score: 513
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.01
    Marker Score: 123,393
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.97
    Marker Score: 2,382
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.97
    Marker Score: 19,988
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.97
    Marker Score: 972
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.96
    Marker Score: 4,700
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.96
    Marker Score: 820
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.96
    Marker Score: 1,970
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.94
    Marker Score: 560
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.94
    Marker Score: 29,049
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.92
    Marker Score: 30,847
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.91
    Marker Score: 1,077
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.91
    Marker Score: 9,994
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.87
    Marker Score: 486
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.87
    Marker Score: 17,611
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.81
    Marker Score: 6,990
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.8
    Marker Score: 1,247
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 1.8
    Marker Score: 4,564
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.8
    Marker Score: 1,050
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.79
    Marker Score: 7,288
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.77
    Marker Score: 15,178
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 1.77
    Marker Score: 2,557
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.76
    Marker Score: 984
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 1.73
    Marker Score: 5,804
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.72
    Marker Score: 2,440
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.72
    Marker Score: 2,130
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.72
    Marker Score: 898
  • Cell Name: granule cell (CL0000120)
    Fold Change: 1.72
    Marker Score: 12,942
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.71
    Marker Score: 1,484
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.71
    Marker Score: 17,609
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 1.7
    Marker Score: 22,635
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.7
    Marker Score: 952
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.69
    Marker Score: 1,688
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.68
    Marker Score: 2,032
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.68
    Marker Score: 1,707
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.68
    Marker Score: 1,797
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.68
    Marker Score: 57,029
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.67
    Marker Score: 813
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.66
    Marker Score: 1,751
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 1.66
    Marker Score: 1,491
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.66
    Marker Score: 4,745
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.64
    Marker Score: 614
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.64
    Marker Score: 448
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 1.62
    Marker Score: 3,719
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.61
    Marker Score: 15,283
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 1.6
    Marker Score: 507
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.6
    Marker Score: 5,671
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 1.59
    Marker Score: 1,213
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 1.59
    Marker Score: 1,710
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.58
    Marker Score: 8,490
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 1.58
    Marker Score: 816
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.57
    Marker Score: 4,216
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.56
    Marker Score: 10,060
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 1.54
    Marker Score: 3,795

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** MEF2A is a transcription factor that binds to specific DNA sequences, regulating the expression of target genes. It is a member of the MEF2 family, which consists of four members: MEF2A, MEF2B, MEF2C, and MEF2D. MEF2A is characterized by its ability to bind to specific DNA sequences, known as MEF2 elements, which are found in the promoter regions of target genes. MEF2A also interacts with other transcription factors, such as NFAT and AP-1, to regulate gene expression. Additionally, MEF2A is involved in the regulation of cell differentiation, particularly in the development of cardiac myocytes and muscle cells. **Pathways and Functions** MEF2A is involved in various signaling pathways, including: 1. **Cardiac Conduction**: MEF2A regulates the expression of genes involved in cardiac conduction, including those involved in the development and maintenance of the cardiac conduction system. 2. **Cell Differentiation**: MEF2A is involved in the regulation of cell differentiation, particularly in the development of cardiac myocytes and muscle cells. 3. **Immune Response**: MEF2A is expressed in immune cells, including microglial cells and macrophages, and is involved in the regulation of immune responses, including the production of cytokines and the activation of immune cells. 4. **Cytokine Signaling**: MEF2A interacts with cytokine receptors, including those involved in the signaling pathways of IL-17 and TNF-α. 5. **Cardiac Hypertrophy**: MEF2A regulates the expression of genes involved in cardiac hypertrophy, including those involved in the development and maintenance of cardiac muscle cells. **Clinical Significance** MEF2A has been implicated in various diseases, including: 1. **Cardiac Arrhythmias**: Abnormal expression of MEF2A has been linked to cardiac arrhythmias, including atrial fibrillation and ventricular tachycardia. 2. **Muscular Dystrophy**: MEF2A is involved in the regulation of muscle differentiation, and abnormalities in MEF2A have been linked to muscular dystrophy. 3. **Autoimmune Diseases**: MEF2A is involved in the regulation of immune responses, and abnormalities in MEF2A have been linked to autoimmune diseases, including multiple sclerosis and rheumatoid arthritis. In conclusion, MEF2A is a transcription factor that plays a crucial role in various cellular processes, including cell differentiation, development, and immune response. Its dysregulation has been implicated in various diseases, highlighting the importance of MEF2A in maintaining tissue homeostasis and preventing disease.

Genular Protein ID: 218110147

Symbol: MEF2A_HUMAN

Name: Myocyte-specific enhancer factor 2A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1748287

Title: Human SRF-related proteins: DNA-binding properties and potential regulatory targets.

PubMed ID: 1748287

DOI: 10.1101/gad.5.12a.2327

PubMed ID: 1516833

Title: Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors.

PubMed ID: 1516833

DOI: 10.1101/gad.6.9.1783

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9753748

Title: Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1.

PubMed ID: 9753748

DOI: 10.1093/nar/26.20.4771

PubMed ID: 10487761

Title: HDAC4 deacetylase associates with and represses the MEF2 transcription factor.

PubMed ID: 10487761

DOI: 10.1093/emboj/18.18.5099

PubMed ID: 9858528

Title: Regulation of the MEF2 family of transcription factors by p38.

PubMed ID: 9858528

DOI: 10.1128/mcb.19.1.21

PubMed ID: 10330143

Title: Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors.

PubMed ID: 10330143

DOI: 10.1128/mcb.19.6.4028

PubMed ID: 10849446

Title: Big mitogen-activated kinase regulates multiple members of the MEF2 protein family.

PubMed ID: 10849446

DOI: 10.1074/jbc.m001573200

PubMed ID: 11904443

Title: Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis.

PubMed ID: 11904443

DOI: 10.1073/pnas.022036399

PubMed ID: 12586839

Title: Phosphorylation motifs regulating the stability and function of myocyte enhancer factor 2A.

PubMed ID: 12586839

DOI: 10.1074/jbc.m211312200

PubMed ID: 12691662

Title: Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis.

PubMed ID: 12691662

DOI: 10.1016/s0896-6273(03)00191-0

PubMed ID: 14630949

Title: Regulation of the human GLUT4 gene promoter: interaction between a transcriptional activator and myocyte enhancer factor 2A.

PubMed ID: 14630949

DOI: 10.1073/pnas.2432756100

PubMed ID: 15834131

Title: Alternative pre-mRNA splicing governs expression of a conserved acidic transactivation domain in myocyte enhancer factor 2 factors of striated muscle and brain.

PubMed ID: 15834131

DOI: 10.1074/jbc.m502491200

PubMed ID: 15888658

Title: Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2.

PubMed ID: 15888658

DOI: 10.1523/jneurosci.1331-05.2005

PubMed ID: 16563226

Title: SUMO-1 modification of MEF2A regulates its transcriptional activity.

PubMed ID: 16563226

DOI: 10.1111/j.1582-4934.2006.tb00295.x

PubMed ID: 16371476

Title: PDSM, a motif for phosphorylation-dependent SUMO modification.

PubMed ID: 16371476

DOI: 10.1073/pnas.0503698102

PubMed ID: 16484498

Title: A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation.

PubMed ID: 16484498

DOI: 10.1126/science.1122513

PubMed ID: 17785444

Title: Nemo-like kinase-myocyte enhancer factor 2A signaling regulates anterior formation in Xenopus development.

PubMed ID: 17785444

DOI: 10.1128/mcb.01481-07

PubMed ID: 18697823

Title: Quantitative control of adaptive cardiac hypertrophy by acetyltransferase p300.

PubMed ID: 18697823

DOI: 10.1161/circulationaha.107.760488

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21468593

Title: Identification of HZF1 as a novel target gene of the MEF2 transcription factor.

PubMed ID: 21468593

DOI: 10.3892/mmr.2011.465

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 15496429

Title: Transcription factor MEF2A mutations in patients with coronary artery disease.

PubMed ID: 15496429

DOI: 10.1093/hmg/ddh329

PubMed ID: 15958500

Title: The Pro279Leu variant in the transcription factor MEF2A is associated with myocardial infarction.

PubMed ID: 15958500

DOI: 10.1136/jmg.2005.035071

PubMed ID: 18086930

Title: Lack of association between the MEF2A gene and myocardial infarction.

PubMed ID: 18086930

DOI: 10.1161/circulationaha.107.728485

PubMed ID: 10835359

Title: Solution structure of the MEF2A-DNA complex: structural basis for the modulation of DNA bending and specificity by MADS-box transcription factors.

PubMed ID: 10835359

DOI: 10.1093/emboj/19.11.2615

PubMed ID: 10715212

Title: Crystal structure of MEF2A core bound to DNA at 1.5 A resolution.

PubMed ID: 10715212

DOI: 10.1006/jmbi.2000.3568

Sequence Information:

  • Length: 507
  • Mass: 54811
  • Checksum: 362BA4FBCC792CE2
  • Sequence:
  • MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS SNKLFQYAST 
    DMDKVLLKYT EYNEPHESRT NSDIVEALNK KEHRGCDSPD PDTSYVLTPH TEEKYKKINE 
    EFDNMMRNHK IAPGLPPQNF SMSVTVPVTS PNALSYTNPG SSLVSPSLAA SSTLTDSSML 
    SPPQTTLHRN VSPGAPQRPP STGNAGGMLS TTDLTVPNGA GSSPVGNGFV NSRASPNLIG 
    ATGANSLGKV MPTKSPPPPG GGNLGMNSRK PDLRVVIPPS SKGMMPPLSE EEELELNTQR 
    ISSSQATQPL ATPVVSVTTP SLPPQGLVYS AMPTAYNTDY SLTSADLSAL QGFNSPGMLS 
    LGQVSAWQQH HLGQAALSSL VAGGQLSQGS NLSINTNQNI SIKSEPISPP RDRMTPSGFQ 
    QQQQQQQQQQ PPPPPQPQPQ PPQPQPRQEM GRSPVDSLSS SSSSYDGSDR EDPRGDFHSP 
    IVLGRPPNTE DRESPSVKRM RMDAWVT

Genular Protein ID: 615192611

Symbol: A0A0S2Z4N0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 505
  • Mass: 54442
  • Checksum: E0032FA6F955D7F7
  • Sequence:
  • MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS SNKLFQYAST 
    DMDKVLLKYT EYNEPHESRT NSDIVETLRK KGLNGCESPD ADDYFEHSPL SEDRFSKLNE 
    DSDFIFKRGP PGLPPQNFSM SVTVPVTSPN ALSYTNPGSS LVSPSLAASS TLTDSSMLSP 
    PQTTLHRNVS PGAPQRPPST GNAGGMLSTT DLTVPNGAGS SPVGNGFVNS RASPNLIGAT 
    GANSLGKVMP TKSPPPPGGG NLGMNSRKPD LRVVIPPSSK GMMPPLSEEE ELELNTQRIS 
    SSQATQPLAT PVVSVTTPSL PPQGLVYSAM PTAYNTDYSL TSADLSALQG FNSPGMLSLG 
    QVSAWQQHHL GQAALSSLVA GGQLSQGSNL SINTNQNISI KSEPISPPRD RMTPSGFQQQ 
    QQQQQQQQPP PPPQPQPQPP QPQPRQEMGR SPVDSLSSSS SSYDGSDRED PRGDFHSPIV 
    LGRPPNTEDR ESPSVKRMRM DAWVT

Genular Protein ID: 3999949473

Symbol: A8K720_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 495
  • Mass: 53255
  • Checksum: 44EBB2734D63B74C
  • Sequence:
  • MGRRKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS SNKLFQYAST 
    DMDKVLLKYT EYNEPHESRT NSDIVETLRK KGLNGCESPD ADDYFEHSPL SEDRFSKLNE 
    DSDFIFKRGP PGLPPQNFSM SVTVPVTSPN ALSYTNPGSS LVSPSLAASS TLTDSSMLSP 
    PQTTLHRNVS PGAPQRPPST GNAGGMLSTT DLTVPNGAGS SPVGNGFVNS RASPNLIGAT 
    GANSLGKVMP TKSPPPPGGG NLGMNSRKPD LRVVIPPSSK GMMPPLNTQR ISSSQATQPL 
    ATPVVSVTTP SLPPQGLVYS AMPTAYNTDY SLTSADLSAL QGFNSPGMLS LGQVSAWQQH 
    HLGQAALSSL VAGGQLSQGS NLSINTNQNI SIKSEPISPP RDRMTPSGFQ QQQQQQQQPP 
    PPPQPQPQPP QPQPRQEMGR SPVDSLSSSS SSYDGSDRED PRGDFHSPIV LGRPPNTEDR 
    ESPSVKRMRM DAWVT

Genular Protein ID: 3240433943

Symbol: A0A8I5KVQ4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

Sequence Information:

  • Length: 511
  • Mass: 55227
  • Checksum: 32617CFBEFF14532
  • Sequence:
  • MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS SNKLFQYAST 
    DMDKVLLKYT EYNEPHESRT NSDIVEALNK KEHRGCDSPD PDTSYVLTPH TEEKYKKINE 
    EFDNMMRNHK IAVSTKPGLP PQNFSMSVTV PVTSPNALSY TNPGSSLVSP SLAASSTLTD 
    SSMLSPPQTT LHRNVSPGAP QRPPSTGNAG GMLSTTDLTV PNGAGSSPVG NGFVNSRASP 
    NLIGATGANS LGKVMPTKSP PPPGGGNLGM NSRKPDLRVV IPPSSKGMMP PLSEEEELEL 
    NTQRISSSQA TQPLATPVVS VTTPSLPPQG LVYSAMPTAY NTDYSLTSAD LSALQGFNSP 
    GMLSLGQVSA WQQHHLGQAA LSSLVAGGQL SQGSNLSINT NQNISIKSEP ISPPRDRMTP 
    SGFQQQQQQQ QQQQPPPPPQ PQPQPPQPQP RQEMGRSPVD SLSSSSSSYD GSDREDPRGD 
    FHSPIVLGRP PNTEDRESPS VKRMRMDAWV T

Genular Protein ID: 610107293

Symbol: A0A0S2Z454_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 499
  • Mass: 53852
  • Checksum: FE3A83DDCE477C27
  • Sequence:
  • MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS SNKLFQYAST 
    DMDKVLLKYT EYNEPHESRT NSDIVEALNK KEHRGCDSPD PDTSYVLTPH TEEKYKKINE 
    EFDNMMRNHK IAPGLPPQNF SMSVTVPVTS PNALSYTNPG SSLVSPSLAA SSTLTDSSML 
    SPPQTTLHRN VSPGAPQRPP STGNAGGMLS TTDLTVPNGA GSSPVGNGFV NSRASPNLIG 
    ATGANSLGKV MPTKSPPPPG GGNLGMNSRK PDLRVVIPPS SKGMMPPLNT QRISSSQATQ 
    PLATPVVSVT TPSLPPQGLV YSAMPTAYNT DYSLTSADLS ALQGFNSPGM LSLGQVSAWQ 
    QHHLGQAALS SLVAGGQLSQ GSNLSINTNQ NISIKSEPIS PPRDRMTPSG FQQQQQQQQQ 
    QQPPPPPQPQ PQPPQPQPRQ EMGRSPVDSL SSSSSSYDGS DREDPRGDFH SPIVLGRPPN 
    TEDRESPSVK RMRMDAWVT

Genular Protein ID: 3468921167

Symbol: A0A0S2Z4C8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 429
  • Mass: 45570
  • Checksum: B356416F17385FCD
  • Sequence:
  • MGRKKIQITR IMDERNRQTL RKKGLNGCES PDADDYFEHS PLSEDRFSKL NEDSDFIFKR 
    GPPGLPPQNF SMSVTVPVTS PNALSYTNPG SSLVSPSLAA SSTLTDSSML SPPQTTLHRN 
    VSPGAPQRPP STGNAGGMLS TTDLTVPNGA GSSPVGNGFV NSRASPNLIG ATGANSLGKV 
    MPTKSPPPPG GGNLGMNSRK PDLRVVIPPS SKGMMPPLNT QRISSSQATQ PLATPVVSVT 
    TPSLPPQGLV YSAMPTAYNT DYSLTSADLS ALQGFNSPGM LSLGQVSAWQ QHHLGQAALS 
    SLVAGGQLSQ GSNLSINTNQ NISIKSEPIS PPRDRMTPSG FQQQQQQQQQ QQPPPPPQPQ 
    PQPPQPQPRQ EMGRSPVDSL SSSSSSYDGS DREDPRGDFH SPIVLGRPPN TEDRESPSVK 
    RMRMDAWVT

Genular Protein ID: 458520458

Symbol: A0A0S2Z417_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 497
  • Mass: 53483
  • Checksum: F4A61D805AE448AF
  • Sequence:
  • MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS SNKLFQYAST 
    DMDKVLLKYT EYNEPHESRT NSDIVETLRK KGLNGCESPD ADDYFEHSPL SEDRFSKLNE 
    DSDFIFKRGP PGLPPQNFSM SVTVPVTSPN ALSYTNPGSS LVSPSLAASS TLTDSSMLSP 
    PQTTLHRNVS PGAPQRPPST GNAGGMLSTT DLTVPNGAGS SPVGNGFVNS RASPNLIGAT 
    GANSLGKVMP TKSPPPPGGG NLGMNSRKPD LRVVIPPSSK GMMPPLNTQR ISSSQATQPL 
    ATPVVSVTTP SLPPQGLVYS AMPTAYNTDY SLTSADLSAL QGFNSPGMLS LGQVSAWQQH 
    HLGQAALSSL VAGGQLSQGS NLSINTNQNI SIKSEPISPP RDRMTPSGFQ QQQQQQQQQQ 
    PPPPPQPQPQ PPQPQPRQEM GRSPVDSLSS SSSSYDGSDR EDPRGDFHSP IVLGRPPNTE 
    DRESPSVKRM RMDAWVT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.