Details for: MID1

Gene ID: 4281

Symbol: MID1

Ensembl ID: ENSG00000101871

Description: midline 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 301.2629
    Cell Significance Index: -46.8600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 185.0236
    Cell Significance Index: -46.9300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 37.3713
    Cell Significance Index: -35.6800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 16.3428
    Cell Significance Index: -43.7800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 12.1448
    Cell Significance Index: -26.5800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.8878
    Cell Significance Index: -46.9100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 4.6057
    Cell Significance Index: 258.4500
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 3.9767
    Cell Significance Index: 24.5400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.8731
    Cell Significance Index: 39.2000
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.7567
    Cell Significance Index: 24.4700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.6916
    Cell Significance Index: 534.1600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.4314
    Cell Significance Index: 67.9500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 2.2094
    Cell Significance Index: 55.2300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.8543
    Cell Significance Index: 36.1900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.4012
    Cell Significance Index: 138.6100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.2670
    Cell Significance Index: 1143.9600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.1388
    Cell Significance Index: 59.1600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7804
    Cell Significance Index: 126.9200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.7544
    Cell Significance Index: 15.7900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6979
    Cell Significance Index: 75.9200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.6870
    Cell Significance Index: 31.1400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5630
    Cell Significance Index: 201.9600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5421
    Cell Significance Index: 41.6000
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.4828
    Cell Significance Index: 4.8700
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.4777
    Cell Significance Index: 6.0200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3993
    Cell Significance Index: 8.6500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3714
    Cell Significance Index: 74.5100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3646
    Cell Significance Index: 10.5100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3058
    Cell Significance Index: 194.2300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3028
    Cell Significance Index: 37.2400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2803
    Cell Significance Index: 527.6800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2247
    Cell Significance Index: 42.7600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2037
    Cell Significance Index: 3.4900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1882
    Cell Significance Index: 289.6700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.1758
    Cell Significance Index: 109.7800
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.1748
    Cell Significance Index: 2.5100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1264
    Cell Significance Index: 4.4400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1125
    Cell Significance Index: 207.5400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1035
    Cell Significance Index: 18.6700
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 0.0965
    Cell Significance Index: 1.3500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0882
    Cell Significance Index: 48.1800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0652
    Cell Significance Index: 45.0900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0458
    Cell Significance Index: 20.2600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0347
    Cell Significance Index: 15.7300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.0344
    Cell Significance Index: 3.5800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0154
    Cell Significance Index: 20.9300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0052
    Cell Significance Index: 0.1400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0022
    Cell Significance Index: 0.2800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0241
    Cell Significance Index: -1.6700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0256
    Cell Significance Index: -18.9600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0323
    Cell Significance Index: -4.6900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0399
    Cell Significance Index: -2.4500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0446
    Cell Significance Index: -25.1300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0551
    Cell Significance Index: -40.3900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0552
    Cell Significance Index: -41.7500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0800
    Cell Significance Index: -13.6600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1185
    Cell Significance Index: -34.1000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1486
    Cell Significance Index: -31.2900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1614
    Cell Significance Index: -22.1600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1898
    Cell Significance Index: -24.5200
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: -0.2182
    Cell Significance Index: -0.9500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2210
    Cell Significance Index: -4.5900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2249
    Cell Significance Index: -4.7900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.2461
    Cell Significance Index: -3.5400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2493
    Cell Significance Index: -16.7600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2574
    Cell Significance Index: -29.4900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2809
    Cell Significance Index: -32.7400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2855
    Cell Significance Index: -13.4200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2896
    Cell Significance Index: -29.5900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3384
    Cell Significance Index: -10.8400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3572
    Cell Significance Index: -40.7700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.3856
    Cell Significance Index: -45.4700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.4243
    Cell Significance Index: -11.5500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.4270
    Cell Significance Index: -30.2000
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.4427
    Cell Significance Index: -2.7800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4442
    Cell Significance Index: -23.1400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4601
    Cell Significance Index: -21.4500
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.4625
    Cell Significance Index: -6.9300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.5061
    Cell Significance Index: -7.4700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.5082
    Cell Significance Index: -4.6800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5185
    Cell Significance Index: -31.7900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5276
    Cell Significance Index: -41.7900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5694
    Cell Significance Index: -42.4400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.6472
    Cell Significance Index: -18.4700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6529
    Cell Significance Index: -41.1500
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.6784
    Cell Significance Index: -11.7300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.6846
    Cell Significance Index: -44.1700
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.6993
    Cell Significance Index: -4.1500
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.7304
    Cell Significance Index: -5.3100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.7380
    Cell Significance Index: -16.1600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7791
    Cell Significance Index: -34.4600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.8267
    Cell Significance Index: -43.4100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.8779
    Cell Significance Index: -13.2300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.9603
    Cell Significance Index: -13.6700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.9791
    Cell Significance Index: -19.3600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.9829
    Cell Significance Index: -32.1800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.9932
    Cell Significance Index: -37.6100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.0036
    Cell Significance Index: -29.5600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.0066
    Cell Significance Index: -32.0600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.0263
    Cell Significance Index: -29.4200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MID1 is a ubiquitin-protein ligase that plays a pivotal role in regulating microtubule dynamics, maintaining the stability of the cytoskeleton, and modulating immune responses. This gene exhibits high expression levels in various cell types, including neuronal brush cells, stellate neurons, epithelial cells, and immune cells such as astrocytes and CNS interneurons. Notably, MID1 is also expressed in specific tissues, such as the prostate and lower respiratory tract, underscoring its potential involvement in tissue-specific functions. **Pathways and Functions:** MID1 interacts with multiple signaling pathways, including cytokine signaling in the immune system, interferon gamma signaling, and stress-activated MAPK cascades. These interactions enable MID1 to regulate microtubule dynamics, modulate protein localization, and influence the organization of the cytoskeleton. Furthermore, MID1 has been implicated in the regulation of microtubule cytoskeleton organization, negative regulation of microtubule depolymerization, and pattern specification processes. **Clinical Significance:** The dysregulation of MID1 has been linked to various diseases, including neurological disorders, cancer, and immune-mediated conditions. For instance, MID1 expression has been observed to be altered in neurodegenerative diseases, such as Alzheimer's and Parkinson's, suggesting a potential role in disease pathology. Additionally, MID1 has been implicated in the development and progression of certain cancers, including prostate cancer, where it may contribute to tumor growth and metastasis. Moreover, MID1 has been shown to modulate immune responses, making it a potential target for therapeutic interventions in autoimmune and inflammatory diseases. **Potential Implications:** The study of MID1 highlights the intricate relationships between microtubule organization, immune regulation, and cellular signaling pathways. Further research is warranted to elucidate the functional mechanisms underlying MID1's role in disease contexts and to explore its therapeutic potential. By investigating the molecular mechanisms governing MID1's activity, researchers may uncover novel targets for the treatment of diseases characterized by dysregulated immune responses and cytoskeletal dysfunction. **Future Directions:** To fully appreciate the significance of MID1, future studies should focus on: 1. Elucidating the molecular mechanisms underlying MID1's interactions with signaling pathways and microtubule dynamics. 2. Investigating the role of MID1 in specific disease contexts, such as neurodegenerative disorders and cancer. 3. Exploring the therapeutic potential of targeting MID1 in disease contexts, including immune-mediated conditions and cancer. 4. Investigating the tissue-specific expression patterns of MID1 and its functional implications in different cell types. By advancing our understanding of MID1's complex biology, researchers may uncover novel therapeutic strategies for the treatment of diseases characterized by dysregulated immune responses and cytoskeletal dysfunction.

Genular Protein ID: 602267897

Symbol: TRI18_HUMAN

Name: E3 ubiquitin-protein ligase Midline-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9354791

Title: Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22.

PubMed ID: 9354791

DOI: 10.1038/ng1197-285

PubMed ID: 9425238

Title: The human FXY gene is located within Xp22.3: implications for evolution of the mammalian X chromosome.

PubMed ID: 9425238

DOI: 10.1093/hmg/7.2.299

PubMed ID: 9722948

Title: Characterization and physical mapping in human and mouse of a novel RING finger gene in Xp22.

PubMed ID: 9722948

DOI: 10.1006/geno.1998.5350

PubMed ID: 11030761

Title: New mutations in MID1 provide support for loss of function as the cause of X-linked Opitz syndrome.

PubMed ID: 11030761

DOI: 10.1093/hmg/9.17.2553

PubMed ID: 11331580

Title: The tripartite motif family identifies cell compartments.

PubMed ID: 11331580

DOI: 10.1093/emboj/20.9.2140

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10400985

Title: Functional characterization of the Opitz syndrome gene product (midin): evidence for homodimerization and association with microtubules throughout the cell cycle.

PubMed ID: 10400985

DOI: 10.1093/hmg/8.8.1387

PubMed ID: 10077590

Title: The Opitz syndrome gene product, MID1, associates with microtubules.

PubMed ID: 10077590

DOI: 10.1073/pnas.96.6.2794

PubMed ID: 11685209

Title: MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation.

PubMed ID: 11685209

DOI: 10.1038/ng762

PubMed ID: 11806752

Title: MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, Alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.

PubMed ID: 11806752

DOI: 10.1186/1471-2121-3-1

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22613722

Title: Monoubiquitination promotes calpain cleavage of the protein phosphatase 2A (PP2A) regulatory subunit alpha4, altering PP2A stability and microtubule-associated protein phosphorylation.

PubMed ID: 22613722

DOI: 10.1074/jbc.m112.368613

PubMed ID: 22629402

Title: TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members.

PubMed ID: 22629402

DOI: 10.1371/journal.pone.0037470

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 16529770

Title: Solution structure of the RBCC/TRIM B-box1 domain of human MID1: B-box with a RING.

PubMed ID: 16529770

DOI: 10.1016/j.jmb.2006.02.009

PubMed ID: 9718340

Title: Opitz G/BBB syndrome in Xp22: mutations in the MID1 gene cluster in the carboxy-terminal domain.

PubMed ID: 9718340

DOI: 10.1086/302010

PubMed ID: 15558842

Title: Mild phenotypes in a series of patients with Opitz GBBB syndrome with MID1 mutations.

PubMed ID: 15558842

DOI: 10.1002/ajmg.a.30407

Sequence Information:

  • Length: 667
  • Mass: 75251
  • Checksum: 673C5120018BA619
  • Sequence:
  • METLESELTC PICLELFEDP LLLPCAHSLC FNCAHRILVS HCATNESVES ITAFQCPTCR 
    HVITLSQRGL DGLKRNVTLQ NIIDRFQKAS VSGPNSPSET RRERAFDANT MTSAEKVLCQ 
    FCDQDPAQDA VKTCVTCEVS YCDECLKATH PNKKPFTGHR LIEPIPDSHI RGLMCLEHED 
    EKVNMYCVTD DQLICALCKL VGRHRDHQVA ALSERYDKLK QNLESNLTNL IKRNTELETL 
    LAKLIQTCQH VEVNASRQEA KLTEECDLLI EIIQQRRQII GTKIKEGKVM RLRKLAQQIA 
    NCKQCIERSA SLISQAEHSL KENDHARFLQ TAKNITERVS MATASSQVLI PEINLNDTFD 
    TFALDFSREK KLLECLDYLT APNPPTIREE LCTASYDTIT VHWTSDDEFS VVSYELQYTI 
    FTGQANVVSL CNSADSWMIV PNIKQNHYTV HGLQSGTKYI FMVKAINQAG SRSSEPGKLK 
    TNSQPFKLDP KSAHRKLKVS HDNLTVERDE SSSKKSHTPE RFTSQGSYGV AGNVFIDSGR 
    HYWEVVISGS TWYAIGLAYK SAPKHEWIGK NSASWALCRC NNNWVVRHNS KEIPIEPAPH 
    LRRVGILLDY DNGSIAFYDA LNSIHLYTFD VAFAQPVCPT FTVWNKCLTI ITGLPIPDHL 
    DCTEQLP

Genular Protein ID: 3715963143

Symbol: A0A8I5KPE0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 489
  • Mass: 55451
  • Checksum: BC081B2DF9B8CCEC
  • Sequence:
  • METLESELTC PICLELFEDP LLLPCAHSLC FNCAHRILVS HCATNESVES ITAFQCPTCR 
    HVITLSQRGL DGLKRNVTLQ NIIDRFQKAS VSGPNSPSET RRERAFDANT MTSAEKVLCQ 
    FCDQDPAQDA VKTCVTCEVS YCDECLKATH PNKKPFTGHR LIEPIPDSHI RGLMCLEHED 
    EKVNMYCVTD DQLICALCKL VGRHRDHQVA ALSERYDKLK QNLESNLTNL IKRNTELETL 
    LAKLIQTCQH VEVNASRQEA KLTEECDLLI EIIQQRRQII GTKIKEGKVM RLRKLAQQIA 
    NCKQCIERSA SLISQAEHSL KENDHARFLQ TAKNITERVS MATASSQVLI PEINLNDTFD 
    TFALDFSREK KLLECLDYLT APNPPTIREE LCTASYDTIT VHWTSDDEFS VVSYELQYTI 
    FTGQANVVSE YLMAYLFLSL VAFFRLIAFL NLNFKGRQGR KEHTIFIDLS FLNKKVIALT 
    CTTLVKTAG

Genular Protein ID: 2539378515

Symbol: A0A8I5KR14_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 629
  • Mass: 70863
  • Checksum: 4CE0E3483F336BA4
  • Sequence:
  • METLESELTC PICLELFEDP LLLPCAHSLC FNCAHRILVS HCATNESVES ITAFQCPTCR 
    HVITLSQRGL DGLKRNVTLQ NIIDRFQKAS VSGPNSPSET RRERAFDANT MTSAEKVLCQ 
    FCDQDPAQDA VKTCVTCEVS YCDECLKATH PNKKPFTGHR LIEPIPDSHI RGLMCLEHED 
    EKQNLESNLT NLIKRNTELE TLLAKLIQTC QHVEVNASRQ EAKLTEECDL LIEIIQQRRQ 
    IIGTKIKEGK VMRLRKLAQQ IANCKQCIER SASLISQAEH SLKENDHARF LQTAKNITER 
    VSMATASSQV LIPEINLNDT FDTFALDFSR EKKLLECLDY LTAPNPPTIR EELCTASYDT 
    ITVHWTSDDE FSVVSYELQY TIFTGQANVV SLCNSADSWM IVPNIKQNHY TVHGLQSGTK 
    YIFMVKAINQ AGSRSSEPGK LKTNSQPFKL DPKSAHRKLK VSHDNLTVER DESSSKKSHT 
    PERFTSQGSY GVAGNVFIDS GRHYWEVVIS GSTWYAIGLA YKSAPKHEWI GKNSASWALC 
    RCNNNWVVRH NSKEIPIEPA PHLRRVGILL DYDNGSIAFY DALNSIHLYT FDVAFAQPVC 
    PTFTVWNKCL TIITGLPIPD HLDCTEQLP

Genular Protein ID: 2016378095

Symbol: A0A087X255_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 540
  • Mass: 61708
  • Checksum: EA6B68F66A99CEAD
  • Sequence:
  • METLESELTC PICLELFEDP LLLPCAHSLC FNCAHRILVS HCATNESVES ITAFQCPTCR 
    HVITLSQRGL DGLKRNVTLQ NIIDRFQKAS VSGPNSPSET RRERAFDANT MTSAEKVLCQ 
    FCDQDPAQDA VKTCVTCEVS YCDECLKATH PNKKPFTGHR LIEPIPDSHI RGLMCLEHED 
    EKVNMYCVTD DQLICALCKL VGRHRDHQVA ALSERYDKLK QNLESNLTNL IKRNTELETL 
    LAKLIQTCQH VETVKDQKVI GREKQQYYPR NRRKWVSNSL QARLMGRRCI SRRERKLTLD 
    VEKVNASRQE AKLTEECDLL IEIIQQRRQI IGTKIKEGKV MRLRKLAQQI ANCKQCIERS 
    ASLISQAEHS LKENDHARFL QTAKNITERV SMATASSQVL IPEINLNDTF DTFALDFSRE 
    KKLLECLDYL TAPNPPTIRE ELCTASYDTI TVHWTSDDEF SVVSYELQYT IFTGQANVVS 
    EYLMAYLFLS LVAFFRLIAF LNLNFKGRQG RKEHTIFIDL SFLNKKVIAL TCTTLVKTAG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.