Details for: MPI

Gene ID: 4351

Symbol: MPI

Ensembl ID: ENSG00000178802

Description: mannose phosphate isomerase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 91.2918
    Cell Significance Index: -14.2000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 36.8628
    Cell Significance Index: -9.3500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 31.0089
    Cell Significance Index: -14.6400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 30.1902
    Cell Significance Index: -12.2700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 12.9249
    Cell Significance Index: -12.3400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 11.5981
    Cell Significance Index: -14.3000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.9237
    Cell Significance Index: -13.1900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.6847
    Cell Significance Index: -14.5400
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 3.2806
    Cell Significance Index: 54.0600
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.2451
    Cell Significance Index: 36.0200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9943
    Cell Significance Index: 897.7600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.9854
    Cell Significance Index: 26.4100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9601
    Cell Significance Index: 104.4400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.9016
    Cell Significance Index: 26.4800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.7954
    Cell Significance Index: 20.3200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6505
    Cell Significance Index: 105.7900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6420
    Cell Significance Index: 33.3500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.6163
    Cell Significance Index: 32.3600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5502
    Cell Significance Index: 11.9200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5273
    Cell Significance Index: 36.4700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.4638
    Cell Significance Index: 29.2300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3902
    Cell Significance Index: 38.6000
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.2829
    Cell Significance Index: 1.7500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2720
    Cell Significance Index: 148.5600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2516
    Cell Significance Index: 7.2500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2409
    Cell Significance Index: 33.0800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2258
    Cell Significance Index: 10.5300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2032
    Cell Significance Index: 36.6300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1923
    Cell Significance Index: 38.5800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1730
    Cell Significance Index: 34.3300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1715
    Cell Significance Index: 32.6400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1535
    Cell Significance Index: 18.8700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1447
    Cell Significance Index: 9.3400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1384
    Cell Significance Index: 17.7400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1328
    Cell Significance Index: 47.6500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1019
    Cell Significance Index: 2.6800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0863
    Cell Significance Index: 38.1500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0861
    Cell Significance Index: 10.1500
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.0701
    Cell Significance Index: 0.5400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0682
    Cell Significance Index: 8.8100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0606
    Cell Significance Index: 1.2900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0575
    Cell Significance Index: 0.7800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0512
    Cell Significance Index: 0.6100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0501
    Cell Significance Index: 1.3400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.0467
    Cell Significance Index: 0.4300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0460
    Cell Significance Index: 1.6200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0373
    Cell Significance Index: 2.8700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0232
    Cell Significance Index: 16.0700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0167
    Cell Significance Index: 0.4600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0042
    Cell Significance Index: 0.3100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0026
    Cell Significance Index: 4.9700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0003
    Cell Significance Index: 0.0100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0007
    Cell Significance Index: -0.0500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0027
    Cell Significance Index: -2.0200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0040
    Cell Significance Index: -6.1200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0044
    Cell Significance Index: -8.0600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0068
    Cell Significance Index: -1.1700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0075
    Cell Significance Index: -0.2000
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.0086
    Cell Significance Index: -0.1100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0087
    Cell Significance Index: -11.8700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0090
    Cell Significance Index: -6.5700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0101
    Cell Significance Index: -1.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0113
    Cell Significance Index: -7.1600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0148
    Cell Significance Index: -0.7700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0153
    Cell Significance Index: -0.7000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0153
    Cell Significance Index: -0.2300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0177
    Cell Significance Index: -13.0800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0218
    Cell Significance Index: -9.8800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0243
    Cell Significance Index: -13.6800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0259
    Cell Significance Index: -16.1900
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0290
    Cell Significance Index: -0.6700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0400
    Cell Significance Index: -0.8300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0417
    Cell Significance Index: -12.0100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0433
    Cell Significance Index: -4.9600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0444
    Cell Significance Index: -1.2400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0535
    Cell Significance Index: -0.9000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0545
    Cell Significance Index: -3.0600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.0548
    Cell Significance Index: -0.4600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0552
    Cell Significance Index: -8.0200
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.0639
    Cell Significance Index: -0.5100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0661
    Cell Significance Index: -4.0700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0723
    Cell Significance Index: -8.4300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0779
    Cell Significance Index: -16.4100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1243
    Cell Significance Index: -8.3600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1308
    Cell Significance Index: -4.1900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1325
    Cell Significance Index: -13.8000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1328
    Cell Significance Index: -2.7800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1331
    Cell Significance Index: -1.0900
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.1350
    Cell Significance Index: -0.8800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1480
    Cell Significance Index: -11.7200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1628
    Cell Significance Index: -1.6900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1691
    Cell Significance Index: -7.4800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1742
    Cell Significance Index: -3.8200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1961
    Cell Significance Index: -12.0200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2099
    Cell Significance Index: -7.9500
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.2395
    Cell Significance Index: -1.5900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2433
    Cell Significance Index: -4.1700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2530
    Cell Significance Index: -7.2200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2708
    Cell Significance Index: -6.9600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MPI is a bifunctional enzyme that catalyzes the isomerization of mannose-6-phosphate to fructose-6-phosphate, a critical step in the biosynthesis of LLOs. This enzyme is highly specific, with a substrate specificity for mannose-6-phosphate and a low affinity for other sugars. MPI is also a zinc-dependent enzyme, with a zinc ion binding site that plays a crucial role in its catalytic activity. The enzyme is widely expressed in various cell types, including neural progenitor cells, GABAergic interneurons, and stem cells from the intestinal crypt. **Pathways and Functions:** MPI is integral to the glycosylation pathway, which involves the synthesis of LLOs and their subsequent transfer to nascent proteins. The enzyme is involved in the following pathways: 1. Biosynthesis of the N-linked glycosylation precursor (LLO): MPI catalyzes the isomerization of mannose-6-phosphate to fructose-6-phosphate, which is then incorporated into the LLO. 2. Asparagine n-linked glycosylation: MPI is involved in the addition of carbohydrate molecules to asparagine-containing proteins. 3. Cytosol: MPI is localized to the cytosol, where it facilitates the biosynthesis of LLOs. **Clinical Significance:** Dysregulation of MPI has been implicated in various diseases, including: 1. MPI-Cdg (Mannose Phosphate Isomerase-CDG): a genetic disorder characterized by impaired glycosylation and clinical manifestations such as developmental delay, seizures, and intellectual disability. 2. Glycosylation precursor biosynthesis disorders: MPI-Cdg is a member of a group of disorders characterized by impaired glycosylation and clinical manifestations such as developmental delay, seizures, and intellectual disability. 3. Neurodegenerative disorders: MPI has been implicated in the pathogenesis of neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease, where impaired glycosylation can lead to protein misfolding and aggregation. In conclusion, MPI is a critical enzyme involved in the biosynthesis of N-linked glycosylation precursors, and its dysregulation has significant clinical implications. Further research is needed to elucidate the molecular mechanisms underlying MPI dysfunction and to develop therapeutic strategies for the treatment of MPI-related disorders.

Genular Protein ID: 1835361395

Symbol: MPI_HUMAN

Name: Mannose-6-phosphate isomerase

UniProtKB Accession Codes:

P34949 A8K8K9 Q96AB0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 7 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EC 1 EMBL 8 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OGP 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 Rhea 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8307007

Title: Purification, cDNA cloning and heterologous expression of human phosphomannose isomerase.

PubMed ID: 8307007

DOI: 10.1111/j.1432-1033.1994.tb19954.x

PubMed ID: 10980531

Title: Genomic organization of the human phosphomannose isomerase (MPI) gene and mutation analysis in patients with congenital disorders of glycosylation type Ib (CDG-Ib).

PubMed ID: 10980531

DOI: 10.1002/1098-1004(200009)16:3<247::aid-humu7>3.0.co;2-a

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 9585601

Title: Phosphomannose isomerase deficiency: a carbohydrate-deficient glycoprotein syndrome with hepatic-intestinal presentation.

PubMed ID: 9585601

DOI: 10.1086/301873

PubMed ID: 9525984

Title: Carbohydrate-deficient glycoprotein syndrome type Ib: phosphomannose isomerase deficiency and mannose therapy.

PubMed ID: 9525984

DOI: 10.1172/jci2350

PubMed ID: 11134235

Title: A broad spectrum of clinical presentations in congenital disorders of glycosylation I: a series of 26 cases.

PubMed ID: 11134235

DOI: 10.1136/jmg.38.1.14

PubMed ID: 11350186

Title: Genetic and metabolic analysis of the first adult with congenital disorder of glycosylation type Ib: long-term outcome and effects of mannose supplementation.

PubMed ID: 11350186

DOI: 10.1006/mgme.2001.3161

PubMed ID: 12357336

Title: DHPLC analysis as a platform for molecular diagnosis of congenital disorders of glycosylation (CDG).

PubMed ID: 12357336

DOI: 10.1038/sj.ejhg.5200858

PubMed ID: 12414827

Title: Protein losing enteropathy-hepatic fibrosis syndrome in Saguenay-Lac St-Jean, Quebec is a congenital disorder of glycosylation type Ib.

PubMed ID: 12414827

DOI: 10.1136/jmg.39.11.849

Sequence Information:

  • Length: 423
  • Mass: 46656
  • Checksum: 1612DD966B86D3AC
  • Sequence:
    • MAAPRVFPLS CAVQQYAWGK MGSNSEVARL LASSDPLAQI AEDKPYAELW MGTHPRGDAK 
ILDNRISQKT LSQWIAENQD SLGSKVKDTF NGNLPFLFKV LSVETPLSIQ AHPNKELAEK 
LHLQAPQHYP DANHKPEMAI ALTPFQGLCG FRPVEEIVTF LKKVPEFQFL IGDEAATHLK 
QTMSHDSQAV ASSLQSCFSH LMKSEKKVVV EQLNLLVKRI SQQAAAGNNM EDIFGELLLQ 
LHQQYPGDIG CFAIYFLNLL TLKPGEAMFL EANVPHAYLK GDCVECMACS DNTVRAGLTP 
KFIDVPTLCE MLSYTPSSSK DRLFLPTRSQ EDPYLSIYDP PVPDFTIMKT EVPGSVTEYK 
VLALDSASIL LMVQGTVIAS TPTTQTPIPL QRGGVLFIGA NESVSLKLTE PKDLLIFRAC 
CLL

Genular Protein ID: 184807364

Symbol: B4DW50_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DW50

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 7 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 2 InterPro 8 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 2 PRINTS 1 PROSITE 2 Pfam 6 RefSeq 1 Rhea 1 RuleBase 3 SUPFAM 1 UniPathway 1

Sequence Information:

  • Length: 373
  • Mass: 41148
  • Checksum: D4E0961FDA577E21
  • Sequence:
    • MGTHPRGDAK ILDNRISQKT LSQWIAENQD SLGSKVKGTF NGNLPFLFKV LSVETPLSIQ 
AHPNKELAEK LHLQAPQHYP DANHKPEMAI ALTPFQGLCG FRPVEEIVTF LKKVPEFQFL 
IGDEAATHLK QTMSHDSQAV ASSLQSCFSH LMKSEKKVVV EQLNLLVKRI SQQAAAGNNM 
EDIFGELLLQ LHQQYPGDIG CFAIYFLNLL TLKPGEAMFL EANVPHAYLK GDCVECMACS 
DNTVRAGLTP KFIDVPTLCE MLSYTPSSSK DRLFLPTRSQ EDPYLSIYDP PVPDFTIMKT 
EVPGSVTEYK VLALDSASIL LMVQGTVIAS TPTTQTPIPL QRGGVLFIGA NESVSLKLTE 
PKDLLIFRAC CLL

Genular Protein ID: 2397190542

Symbol: H3BPP3_HUMAN

Name: N/A

UniProtKB Accession Codes:

H3BPP3

Database IDs:

ARBA 12 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 3 DNASU 1 DisGeNET 1 EC 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 7 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 2 Pfam 4 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 1 SMR 1 SUPFAM 1 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 287
  • Mass: 31905
  • Checksum: CCC9957E2525C8F5
  • Sequence:
    • MAAPRVFPLS CAVQQYAWGK MGSNSEVARL LASSDPLAQI AEDKPYAELW MGTHPRGDAK 
ILDNRISQKT LSQWIAENQD SLGSKVKDTF NGNLPFLFKV LSVETPLSIQ AHPNKELAEK 
LHLQAPQHYP DANHKPEMAI ALTPFQGLCG FRPVEEIVTF LKKVPEFQFL IGDEAATHLK 
QTMSHDSQAV ASSLQSCFSH LMKSEKKVVV EQLNLLVKRI SQQAAAGNNM EDIFGELLLQ 
LHQQYPGDIG CFAIYFLNLL TLKPGEAMFL EANVPHAYLK GGPWLCH

Genular Protein ID: 2439801367

Symbol: F5GX71_HUMAN

Name: N/A

UniProtKB Accession Codes:

F5GX71

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 7 DNASU 1 DisGeNET 1 EC 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 2 GeneTree 1 HGNC 1 InterPro 8 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 2 PRINTS 1 PROSITE 2 PeptideAtlas 2 Pfam 6 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 1 RuleBase 3 SMR 1 SUPFAM 1 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 373
  • Mass: 41206
  • Checksum: D503295EA9C60C7D
  • Sequence:
    • MGTHPRGDAK ILDNRISQKT LSQWIAENQD SLGSKVKDTF NGNLPFLFKV LSVETPLSIQ 
AHPNKELAEK LHLQAPQHYP DANHKPEMAI ALTPFQGLCG FRPVEEIVTF LKKVPEFQFL 
IGDEAATHLK QTMSHDSQAV ASSLQSCFSH LMKSEKKVVV EQLNLLVKRI SQQAAAGNNM 
EDIFGELLLQ LHQQYPGDIG CFAIYFLNLL TLKPGEAMFL EANVPHAYLK GDCVECMACS 
DNTVRAGLTP KFIDVPTLCE MLSYTPSSSK DRLFLPTRSQ EDPYLSIYDP PVPDFTIMKT 
EVPGSVTEYK VLALDSASIL LMVQGTVIAS TPTTQTPIPL QRGGVLFIGA NESVSLKLTE 
PKDLLIFRAC CLL

Genular Protein ID: 1443313903

Symbol: H3BPB8_HUMAN

Name: N/A

UniProtKB Accession Codes:

H3BPB8

Database IDs:

ARBA 9 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 7 DNASU 1 DisGeNET 1 EC 1 EMBL 3 Ensembl 2 GO 4 Gene3D 2 GeneTree 1 HGNC 1 InterPro 8 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 6 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 1 RuleBase 3 SUPFAM 1 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 403
  • Mass: 44450
  • Checksum: 56EA89B969E0C1A0
  • Sequence:
    • MGSNSEVARL LASSDPLAQI AEDKPYAELW MGTHPRGDAK ILDNRISQKT LSQWIAENQD 
SLGSKVKDTF NGNLPFLFKV LSVETPLSIQ AHPNKELAEK LHLQAPQHYP DANHKPEMAI 
ALTPFQGLCG FRPVEEIVTF LKKVPEFQFL IGDEAATHLK QTMSHDSQAV ASSLQSCFSH 
LMKSEKKVVV EQLNLLVKRI SQQAAAGNNM EDIFGELLLQ LHQQYPGDIG CFAIYFLNLL 
TLKPGEAMFL EANVPHAYLK GDCVECMACS DNTVRAGLTP KFIDVPTLCE MLSYTPSSSK 
DRLFLPTRSQ EDPYLSIYDP PVPDFTIMKT EVPGSVTEYK VLALDSASIL LMVQGTVIAS 
TPTTQTPIPL QRGGVLFIGA NESVSLKLTE PKDLLIFRAC CLL

Genular Protein ID: 3960088060

Symbol: Q8NHZ6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8NHZ6 E7ENB3

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 3 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 1 InterPro 7 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 4 ProteomicsDB 1 RefSeq 2 Rhea 1 SUPFAM 1 UniPathway 1

Sequence Information:

  • Length: 267
  • Mass: 29699
  • Checksum: 3222DCD06F3F92FE
  • Sequence:
    • MGSNSEVARL LASSDPLAQI AEDKPYAELW MGTHPRGDAK ILDNRISQKT LSQWIAENQD 
SLGSKVKDTF NGNLPFLFKV LSVETPLSIQ AHPNKELAEK LHLQAPQHYP DANHKPEMAI 
ALTPFQGLCG FRPVEEIVTF LKKVPEFQFL IGDEAATHLK QTMSHDSQAV ASSLQSCFSH 
LMKSEKKVVV EQLNLLVKRI SQQAAAGNNM EDIFGELLLQ LHQQYPGDIG CFAIYFLNLL 
TLKPGEAMFL EANVPHAYLK GGPWLCH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.