Details for: MUC1

Gene ID: 4582

Symbol: MUC1

Ensembl ID: ENSG00000185499

Description: mucin 1, cell surface associated

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 138.3520
    Cell Significance Index: -21.5200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 85.5926
    Cell Significance Index: -21.7100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 43.3468
    Cell Significance Index: -20.4700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 41.5008
    Cell Significance Index: -16.8600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 30.4759
    Cell Significance Index: -20.4500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 17.6802
    Cell Significance Index: -16.8800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 17.6101
    Cell Significance Index: -21.7100
  • Cell Name: epithelial cell of exocrine pancreas (CL1001433)
    Fold Change: 14.4162
    Cell Significance Index: 7.2400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.9814
    Cell Significance Index: -24.0600
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 8.6067
    Cell Significance Index: 32.9600
  • Cell Name: peg cell (CL4033014)
    Fold Change: 7.8447
    Cell Significance Index: 181.2400
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 7.1252
    Cell Significance Index: 43.8500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.6183
    Cell Significance Index: -22.1700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 5.0621
    Cell Significance Index: 46.6200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 3.5298
    Cell Significance Index: 1927.7000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.9232
    Cell Significance Index: 151.8500
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 2.6223
    Cell Significance Index: 27.0500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.8437
    Cell Significance Index: 83.5700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.6269
    Cell Significance Index: 264.6000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.5860
    Cell Significance Index: 172.5100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.5767
    Cell Significance Index: 117.5100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.2967
    Cell Significance Index: 77.8500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.2541
    Cell Significance Index: 58.9400
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 1.2303
    Cell Significance Index: 10.1700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.2168
    Cell Significance Index: 207.7700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 1.0558
    Cell Significance Index: 799.1600
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.0232
    Cell Significance Index: 15.8300
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 0.9727
    Cell Significance Index: 3.3400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.8626
    Cell Significance Index: 59.6500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7771
    Cell Significance Index: 140.1000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.5866
    Cell Significance Index: 66.9600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4252
    Cell Significance Index: 383.9200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3828
    Cell Significance Index: 49.4600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.3512
    Cell Significance Index: 257.4700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2699
    Cell Significance Index: 51.3700
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.2352
    Cell Significance Index: 3.3700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2214
    Cell Significance Index: 6.3800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1861
    Cell Significance Index: 5.9600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1541
    Cell Significance Index: 15.2400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1493
    Cell Significance Index: 18.3600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0974
    Cell Significance Index: 2.0200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0535
    Cell Significance Index: 2.5000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0427
    Cell Significance Index: 1.5000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0413
    Cell Significance Index: 4.7300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0216
    Cell Significance Index: 0.4600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0165
    Cell Significance Index: 0.8300
  • Cell Name: airway submucosal gland collecting duct epithelial cell (CL4033023)
    Fold Change: -0.0043
    Cell Significance Index: -0.0300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0112
    Cell Significance Index: -21.1400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0118
    Cell Significance Index: -8.7100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0163
    Cell Significance Index: -2.0900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0193
    Cell Significance Index: -35.6000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0211
    Cell Significance Index: -13.1900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0228
    Cell Significance Index: -35.1700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0249
    Cell Significance Index: -11.0300
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: -0.0250
    Cell Significance Index: -0.1500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0262
    Cell Significance Index: -35.6800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0293
    Cell Significance Index: -18.6000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0297
    Cell Significance Index: -4.0800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0311
    Cell Significance Index: -3.1800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0334
    Cell Significance Index: -18.8200
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.0371
    Cell Significance Index: -0.4200
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.0389
    Cell Significance Index: -0.2700
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0410
    Cell Significance Index: -1.6800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0507
    Cell Significance Index: -18.1800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0550
    Cell Significance Index: -0.7500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0581
    Cell Significance Index: -26.3600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0614
    Cell Significance Index: -0.9200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0730
    Cell Significance Index: -21.0000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0760
    Cell Significance Index: -1.9000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0777
    Cell Significance Index: -16.3700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0891
    Cell Significance Index: -10.3800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0910
    Cell Significance Index: -18.2500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0939
    Cell Significance Index: -5.7600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1055
    Cell Significance Index: -20.9400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1135
    Cell Significance Index: -2.4600
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.1257
    Cell Significance Index: -1.0400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1270
    Cell Significance Index: -10.0600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1276
    Cell Significance Index: -3.5700
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.1523
    Cell Significance Index: -2.5100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1567
    Cell Significance Index: -22.7800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1932
    Cell Significance Index: -13.6700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1970
    Cell Significance Index: -23.2300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2135
    Cell Significance Index: -22.2300
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: -0.2570
    Cell Significance Index: -2.0500
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.2652
    Cell Significance Index: -3.4200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2766
    Cell Significance Index: -14.4100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3012
    Cell Significance Index: -19.4300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.3238
    Cell Significance Index: -4.8800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3306
    Cell Significance Index: -22.2300
  • Cell Name: eosinophil (CL0000771)
    Fold Change: -0.3404
    Cell Significance Index: -3.0200
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.3465
    Cell Significance Index: -3.6600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3508
    Cell Significance Index: -26.9200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3626
    Cell Significance Index: -9.8700
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: -0.3811
    Cell Significance Index: -4.1300
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: -0.3833
    Cell Significance Index: -3.7500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3942
    Cell Significance Index: -11.6100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3968
    Cell Significance Index: -14.5700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4164
    Cell Significance Index: -26.2500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.4295
    Cell Significance Index: -24.1000
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: -0.4375
    Cell Significance Index: -4.6300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** MUC1 is a transmembrane glycoprotein composed of a large extracellular domain, a transmembrane domain, and a small cytoplasmic domain. Its extracellular domain is characterized by a unique structure, featuring a high degree of O-linked glycosylation, which confers it a negative charge and makes it resistant to proteolytic degradation. This unique structure allows MUC1 to interact with various proteins and signaling molecules, modulating its function in different contexts. One of the most distinctive features of MUC1 is its ability to interact with the tumor suppressor protein p53. This interaction can lead to the inhibition of p53-mediated signaling, promoting cell survival and inhibiting apoptosis in cancer cells. Additionally, MUC1 has been shown to interact with various immune cells, including dendritic cells and macrophages, modulating their function and promoting immune evasion in cancer. **Pathways and Functions** MUC1 is involved in multiple signaling pathways, including: 1. **Immune system:** MUC1 interacts with immune cells, modulating their function and promoting immune evasion in cancer. 2. **Cell adhesion:** MUC1 interacts with integrins and other adhesion molecules, regulating cell adhesion and migration. 3. **DNA damage response:** MUC1 interacts with p53, inhibiting its signaling and promoting cell survival in response to DNA damage. 4. **Glycosylation:** MUC1 is heavily glycosylated, with O-linked glycosylation playing a critical role in its structure and function. 5. **Transcription regulation:** MUC1 interacts with transcription factors, regulating gene expression and promoting tumor progression. **Clinical Significance** MUC1 has been implicated in various cancers, including breast, ovarian, lung, and colorectal cancer. Its expression is often upregulated in tumor tissues, and its overexpression has been associated with poor prognosis and reduced survival rates. MUC1 has also been targeted as a potential therapeutic target in cancer treatment. Strategies include: 1. **MUC1-specific antibodies:** Targeting MUC1 with antibodies has shown promise in preclinical models, promoting anti-tumor responses and inhibiting cancer progression. 2. **MUC1-specific vaccines:** Vaccines targeting MUC1 have been developed, aiming to stimulate an immune response against cancer cells expressing MUC1. 3. **MUC1-specific therapies:** Small molecule inhibitors targeting MUC1 have been developed, aiming to inhibit its signaling and promote anti-tumor responses. Overall, MUC1 is a complex protein with multiple functions and implications in cancer progression. Further research is needed to fully understand its role in cancer and to develop effective therapeutic strategies targeting this protein.

Genular Protein ID: 3885427404

Symbol: MUC1_HUMAN

Name: Mucin-1

UniProtKB Accession Codes:

P15941 A5YRV1 A6ZID9 A6ZIE0 B1AVQ8 B1AVR0 B6ECA1 E7ESE5 E7EUG9 P13931 P15942 P17626 Q0VAP5 Q0VAP6 Q14128 Q14876 Q16437 Q16442 Q16615 Q6S4Y3 Q7Z547 Q7Z548 Q7Z550 Q7Z552 Q9BXA4 Q9UE75 Q9UE76 Q9UQL1 Q9Y4J2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 7 CPTAC 4 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 2 EMBL 40 Ensembl 9 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 7 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MEROPS 1 MIM 4 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 18 PDBsum 18 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 16 Pumba 1 RNAct 1 Reactome 7 RefSeq 20 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2394722

Title: Cloning and sequencing of a human pancreatic tumor mucin cDNA.

PubMed ID: 2394722

DOI: 10.1016/s0021-9258(18)77255-4

PubMed ID: 2318825

Title: Episialin, a carcinoma-associated mucin, is generated by a polymorphic gene encoding splice variants with alternative amino termini.

PubMed ID: 2318825

DOI: 10.1016/s0021-9258(19)39399-8

PubMed ID: 1697589

Title: Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.

PubMed ID: 1697589

DOI: 10.1016/s0021-9258(18)77254-2

PubMed ID: 2268309

Title: Structure and expression of the human polymorphic epithelial mucin gene: an expressed VNTR unit.

PubMed ID: 2268309

DOI: 10.1016/s0006-291x(05)80888-5

PubMed ID: 2351132

Title: Human epithelial tumor antigen cDNA sequences. Differential splicing may generate multiple protein forms.

PubMed ID: 2351132

DOI: 10.1111/j.1432-1033.1990.tb15511.x

PubMed ID: 2112460

Title: A transcribed gene, containing a variable number of tandem repeats, codes for a human epithelial tumor antigen. cDNA cloning, expression of the transfected gene and over-expression in breast cancer tissue.

PubMed ID: 2112460

DOI: 10.1111/j.1432-1033.1990.tb15512.x

PubMed ID: 1688329

Title: Isolation and characterization of an expressed hypervariable gene coding for a breast-cancer-associated antigen.

PubMed ID: 1688329

DOI: 10.1016/0378-1119(90)90242-j

PubMed ID: 7925397

Title: Characterization and molecular cloning of a novel MUC1 protein, devoid of tandem repeats, expressed in human breast cancer tissue.

PubMed ID: 7925397

DOI: 10.1111/j.1432-1033.1994.00787.x

PubMed ID: 9212228

Title: Comparison of MUC-1 mucin expression in epithelial and non-epithelial cancer cell lines and demonstration of a new short variant form (MUC-1/Z).

PubMed ID: 9212228

DOI: 10.1002/(sici)1097-0215(19970703)72:1<87::aid-ijc13>3.0.co;2-7

PubMed ID: 15623537

Title: A novel protein derived from the MUC1 gene by alternative splicing and frameshifting.

PubMed ID: 15623537

DOI: 10.1074/jbc.m406943200

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

PubMed ID: 15969018

Title: Soluble expression of peptide containing MUC1/Y-specific epitope in Escherichia coli and preparation of the antibody.

PubMed ID: 15969018

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3417635

Title: A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats.

PubMed ID: 3417635

DOI: 10.1016/s0021-9258(18)37632-4

PubMed ID: 2597151

Title: Sequence analysis of the 5' region of the human DF3 breast carcinoma-associated antigen gene.

PubMed ID: 2597151

DOI: 10.1016/s0006-291x(89)80014-2

PubMed ID: 8608966

Title: Preoperative diagnosis of thyroid papillary carcinoma by reverse transcriptase polymerase chain reaction of the MUC1 gene.

PubMed ID: 8608966

DOI: 10.1002/(sici)1097-0215(19960328)66:1<55::aid-ijc10>3.0.co;2-a

PubMed ID: 8604237

Title: Mucin mRNA expression in lung adenocarcinoma cell lines and tissues.

PubMed ID: 8604237

DOI: 10.1159/000227547

PubMed ID: 11341784

Title: Identification of MUC1 proteolytic cleavage sites in vivo.

PubMed ID: 11341784

DOI: 10.1006/bbrc.2001.4775

PubMed ID: 15987679

Title: The MUC1 SEA module is a self-cleaving domain.

PubMed ID: 15987679

DOI: 10.1074/jbc.m506047200

PubMed ID: 10373415

Title: High density O-glycosylation on tandem repeat peptide from secretory MUC1 of T47D breast cancer cells.

PubMed ID: 10373415

DOI: 10.1074/jbc.274.26.18165

PubMed ID: 7988707

Title: Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins. Cytokine receptor-like molecules.

PubMed ID: 7988707

DOI: 10.1016/0014-5793(94)01251-2

PubMed ID: 7664271

Title: Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein.

PubMed ID: 7664271

PubMed ID: 7744025

Title: Studies on the order and site specificity of GalNAc transfer to MUC1 tandem repeats by UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase from milk or mammary carcinoma cells.

PubMed ID: 7744025

DOI: 10.1111/j.1432-1033.1995.tb20448.x

PubMed ID: 9139698

Title: Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion.

PubMed ID: 9139698

DOI: 10.1074/jbc.272.19.12492

PubMed ID: 9312074

Title: Localization of O-glycosylation sites on glycopeptide fragments from lactation-associated MUC1. All putative sites within the tandem repeat are glycosylation targets in vivo.

PubMed ID: 9312074

DOI: 10.1074/jbc.272.40.24780

PubMed ID: 9536947

Title: Developmental expression of mucin genes in the human gastrointestinal system.

PubMed ID: 9536947

DOI: 10.1136/gut.42.2.220

PubMed ID: 9597769

Title: Localization of O-glycosylation sites of MUC1 tandem repeats by QTOF ESI mass spectrometry.

PubMed ID: 9597769

DOI: 10.1002/(sici)1096-9888(199804)33:4<358::aid-jms642>3.0.co;2-3

PubMed ID: 9819408

Title: Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin.

PubMed ID: 9819408

DOI: 10.1128/mcb.18.12.7216

PubMed ID: 10197628

Title: The breast cancer-associated MUC1 gene generates both a receptor and its cognate binding protein.

PubMed ID: 10197628

PubMed ID: 11173916

Title: MUC1 mucin core protein binds to the domain 1 of ICAM-1.

PubMed ID: 11173916

DOI: 10.1159/000051917

PubMed ID: 11118479

Title: Mucin MUC1 is seen in cell surface protrusions together with ezrin in immunoelectron tomography and is concentrated at tips of filopodial protrusions in MCF-7 breast carcinoma cells.

PubMed ID: 11118479

DOI: 10.1177/002215540104900107

PubMed ID: 11152665

Title: The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin.

PubMed ID: 11152665

DOI: 10.1074/jbc.c000754200

PubMed ID: 11350974

Title: Identification and topology of variant sequences within individual repeat domains of the human epithelial tumor mucin MUC1.

PubMed ID: 11350974

DOI: 10.1074/jbc.m103187200

PubMed ID: 11483589

Title: The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin.

PubMed ID: 11483589

DOI: 10.1074/jbc.c100359200

PubMed ID: 11877440

Title: Protein kinase C delta regulates function of the DF3/MUC1 carcinoma antigen in beta-catenin signaling.

PubMed ID: 11877440

DOI: 10.1074/jbc.m200436200

PubMed ID: 14521915

Title: Identification of four sites of stimulated tyrosine phosphorylation in the MUC1 cytoplasmic tail.

PubMed ID: 14521915

DOI: 10.1016/j.bbrc.2003.09.030

PubMed ID: 12750561

Title: DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7.

PubMed ID: 12750561

DOI: 10.4161/cbt.2.2.282

PubMed ID: 14688481

Title: MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation.

PubMed ID: 14688481

PubMed ID: 12441351

Title: Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding.

PubMed ID: 12441351

DOI: 10.1074/jbc.m208326200

PubMed ID: 12832415

Title: Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin.

PubMed ID: 12832415

DOI: 10.1074/jbc.m304333200

PubMed ID: 12939402

Title: Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein.

PubMed ID: 12939402

PubMed ID: 15471854

Title: MUC1 membrane trafficking is modulated by multiple interactions.

PubMed ID: 15471854

DOI: 10.1074/jbc.m409360200

PubMed ID: 15710329

Title: Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response.

PubMed ID: 15710329

DOI: 10.1016/j.ccr.2005.01.008

PubMed ID: 16288032

Title: MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin.

PubMed ID: 16288032

DOI: 10.1158/0008-5472.can-05-2474

PubMed ID: 15972891

Title: Transmembrane and secreted MUC1 probes show trafficking-dependent changes in O-glycan core profiles.

PubMed ID: 15972891

DOI: 10.1093/glycob/cwi099

PubMed ID: 15513966

Title: MUC1 (CD227) interacts with lck tyrosine kinase in Jurkat lymphoma cells and normal T cells.

PubMed ID: 15513966

DOI: 10.1189/jlb.0604333

PubMed ID: 16507569

Title: Recycling of MUC1 is dependent on its palmitoylation.

PubMed ID: 16507569

DOI: 10.1074/jbc.m512996200

PubMed ID: 16427018

Title: MUC1 oncoprotein stabilizes and activates estrogen receptor alpha.

PubMed ID: 16427018

DOI: 10.1016/j.molcel.2005.11.030

PubMed ID: 17524503

Title: MUC1 inhibits cell proliferation by a beta-catenin-dependent mechanism.

PubMed ID: 17524503

DOI: 10.1016/j.bbamcr.2007.04.009

PubMed ID: 17308127

Title: Human mucin 1 oncoprotein represses transcription of the p53 tumor suppressor gene.

PubMed ID: 17308127

DOI: 10.1158/0008-5472.can-06-3063

PubMed ID: 17545600

Title: Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells.

PubMed ID: 17545600

DOI: 10.1158/0008-5472.can-06-4647

PubMed ID: 16983337

Title: MUC1 is a novel regulator of ErbB1 receptor trafficking.

PubMed ID: 16983337

DOI: 10.1038/sj.onc.1209976

PubMed ID: 20816948

Title: CA 15-3: uses and limitation as a biomarker for breast cancer.

PubMed ID: 20816948

DOI: 10.1016/j.cca.2010.08.039

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23396133

Title: Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.

PubMed ID: 23396133

DOI: 10.1038/ng.2543

PubMed ID: 16585136

Title: N-glycosylation of the MUC1 mucin in epithelial cells and secretions.

PubMed ID: 16585136

DOI: 10.1093/glycob/cwj110

PubMed ID: 35504880

Title: Structural basis for the synthesis of the core 1 structure by C1GalT1.

PubMed ID: 35504880

DOI: 10.1038/s41467-022-29833-0

Sequence Information:

  • Length: 1255
  • Mass: 122102
  • Checksum: 5E28DFC4C20D9A82
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTV VTGSGHASST PGGEKETSAT QRSSVPSSTE KNAVSMTSSV 
LSSHSPGSGS STTQGQDVTL APATEPASGS AATWGQDVTS VPVTRPALGS TTPPAHDVTS 
APDNKPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDNRPALGS TAPPVHNVTS 
ASGSASGSAS TLVHNGTSAR ATTTPASKST PFSIPSHHSD TPTTLASHST KTDASSTHHS 
SVPPLTSSNH STSPQLSTGV SFFFLSFHIS NLQFNSSLED PSTDYYQELQ RDISEMFLQI 
YKQGGFLGLS NIKFRPGSVV VQLTLAFREG TINVHDVETQ FNQYKTEAAS RYNLTISDVS 
VSDVPFPFSA QSGAGVPGWG IALLVLVCVL VALAIVYLIA LAVCQCRRKN YGQLDIFPAR 
DTYHPMSEYP TYHTHGRYVP PSSTDRSPYE KVSAGNGGSS LSYTNPAVAA TSANL

Genular Protein ID: 2835380164

Symbol: A6ZIE6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6ZIE6

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 177
  • Mass: 19116
  • Checksum: 2C60A683BB1643A0
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NALSTGVSFF FLSFHISNLQ FNSSLEDPST DYYQELQRDI SEMAVCQCRR KNYGQLDIFP 
ARDTYHPMSE YPTYHTHGRY VPPSSTDRSP YEKVSAGNGG SSLSYTNPAV AATSANL

Genular Protein ID: 3126720045

Symbol: A6ZID6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6ZID6

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 241
  • Mass: 25656
  • Checksum: F4AFFB0837464EE2
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAFLQIYKQG GFLGLSNIKF RPGSVVVQLT LAFREGTINV HDVETQFNQY ETEAASRYNL 
TISDVSVSDV PFPFSAQSGA GVPGWGIALL VLVCVLVALA IVYLIALAVC QCRRKNYGQL 
DIFPARDTYH PMSEYPTYHT HGRYVPPSST DRSPYEKVSA GNGGSSLSYT NPAVAATSAN 
L

Genular Protein ID: 2393977749

Symbol: A0A0A0MRB3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MRB3

Database IDs:

ARBA 12 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 2 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 241
  • Mass: 25655
  • Checksum: F919FE9E3F664EE2
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAFLQIYKQG GFLGLSNIKF RPGSVVVQLT LAFREGTINV HDVETQFNQY KTEAASRYNL 
TISDVSVSDV PFPFSAQSGA GVPGWGIALL VLVCVLVALA IVYLIALAVC QCRRKNYGQL 
DIFPARDTYH PMSEYPTYHT HGRYVPPSST DRSPYEKVSA GNGGSSLSYT NPAVAATSAN 
L

Genular Protein ID: 848665009

Symbol: A5YRU5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5YRU5

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 3 SMART 1 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 282
  • Mass: 30431
  • Checksum: 2E431D8053353D57
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NALSTGVSFF FLSFHISNLQ FNSSLEDPST DYYQELQRDI SEMFLQIYKQ GGFLGLSNIK 
FRPGSVVVQL TLAFREGTIN VHDVETQFNQ YKTEAASRYN LTISDVSVSD VPFPFSAQSG 
AGVPGWGIAL LVLVCVLVAL AIVYLIALAV CQCRRKNYGQ LDIFPARDTY HPMSEYPTYH 
THGRYVPPSS TDRSPYEKVS AGNGGSSLSY TNPAVAATSA NL

Genular Protein ID: 3413259241

Symbol: A0A384NPK6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A384NPK6

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 ExpressionAtlas 1 GO 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 RefSeq 1 SAM 2 SMR 1 VEuPathDB 1

Sequence Information:

  • Length: 159
  • Mass: 17090
  • Checksum: 2C3B69F515D73168
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAFNSSLEDP STDYYQELQR DISEMAVCQC RRKNYGQLDI FPARDTYHPM SEYPTYHTHG 
RYVPPSSTDR SPYEKVSAGN GGSSLSYTNP AVAATSANL

Genular Protein ID: 125996330

Symbol: A5YRU7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5YRU7

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 219
  • Mass: 23466
  • Checksum: C0DB674812B59BB5
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAFNSSLEDP STDYYQELQR DISEMFLQIY KQGGFLGLSN IKFRPGSVVV QLTLAFREGT 
INVHDVETQF NQYKTEAASR YNLTISDVSV WGWGARLGHR AAGAGLCSGC AGHCLSHCLG 
CLSVPPKELR AAGHLSSPGY LPSYERVPHL PHPWALCAP

Genular Protein ID: 943576806

Symbol: A6ZIE4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6ZIE4

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 1 GeneTree 1 HGNC 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 189
  • Mass: 20037
  • Checksum: C617B22043CAD95A
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAFNSSLEDP STDYYQELQR DISEMSGAGV PGWGIALLVL VCVLVALAIV YLIALAVCQC 
RRKNYGQLDI FPARDTYHPM SEYPTYHTHG RYVPPSSTDR SPYEKVSAGN GGSSLSYTNP 
AVAATSANL

Genular Protein ID: 1634703192

Symbol: A0A087X0L2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087X0L2

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 239
  • Mass: 25405
  • Checksum: 2D7880F01A8FD2BD
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAIPAPTTTK SCRETFLKWP GSVVVQLTLA FREGTINVHD VETQFNQYKT EAASRYNLTI 
SDVSVSDVPF PFSAQSGAGV PGWGIALLVL VCVLVALAIV YLIALAVCQC RRKNYGQLDI 
FPARDTYHPM SEYPTYHTHG RYVPPSSTDR SPYEKVSAGN GGSSLSYTNP AVAATSANL

Genular Protein ID: 4014158383

Symbol: B6ECB3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B6ECB3

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 RefSeq 1 SAM 3

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 212
  • Mass: 22395
  • Checksum: FF70E57FCE3318E9
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAIPAPTTTK SCRETFLKCF CRFINKGVFW ASPILSSVSD VPFPFSAQSG AGVPGWGIAL 
LVLVCVLVAL AIVYLIALAV CQCRRKNYGQ LDIFPARDTY HPMSEYPTYH THGRYVPPSS 
TDRSPYEKVS AGNGGSSLSY TNPAVAATSA NL

Genular Protein ID: 3646052366

Symbol: A6ZID7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6ZID7

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 RefSeq 1 SAM 3 SMR 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 239
  • Mass: 25378
  • Checksum: B47880EA33840BAC
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAIPAPTTTK SCRETFLKWP GSVVVQLTLA FREGTINVHD VETQFSQYKT EAASRYNLTI 
SDVSVSDVPF PFSAQSGAGV PGWGIALLVL VCVLVALAIV YLIALAVCQC RRKNYGQLDI 
FPARDTYHPM SEYPTYHTHG RYVPPSSTDR SPYEKVSAGN GGSSLSYTNP AVAATSANL

Genular Protein ID: 3024758077

Symbol: A5YRV0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5YRV0

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 238
  • Mass: 25267
  • Checksum: 253AFB230AE79A8D
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAIYKQGGFL GLSNIKFRPG SVVVQLTLAF REGTINVHDV ETQFNQYKTE AASRYNLTIS 
DVSVSDVPFP FSAQSGAGVP GWGIALLVLV CVLVALAIVY LIALAVCQCR RKNYGQLDIF 
PARDTYHPMS EYPTYHTHGR YVPPSSTDRS PYEKVSAGNG GSSLSYTNPA VAATSANL

Genular Protein ID: 1502339803

Symbol: A0A0C4DGW3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DGW3

Database IDs:

ARBA 12 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 2 MEROPS 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 1 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 475
  • Mass: 49224
  • Checksum: CB64D56690818614
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTV VTGSGHASST PGGEKETSAT QRSSVPSSTE KNAVSMTSSV 
LSSHSPGSGS STTQGQDVTL APATEPASGS AATWGQDVTS VPVTRPALGS TTPPAHDVTS 
APDNKPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDNRPALGS TAPPVHNVTS 
ASGSASGSAS TLVHNGTSAR ATTTPASKST PFSIPSHHSD TPTTLASHST KTDASSTHHS 
TVPPLTSSNH STSPQLSTGV SFFFLSFHIS NLQFNSSLED PSTDYYQELQ RDISEMFLQI 
YKQGGFLGLS NIKFRPGSVV VQLTLAFREG TINVHDVETQ FNQYKTEAAS RYNLTISDVS 
VSDVPFPFSA QSGAGVPGWG IALLVLVCVL VALAIVYLIA LAVCQCRRKN YGQLDIFPAR 
DTYHPMSEYP TYHTHGRYVP PSSTDRSPYE KVSAGNGGSS LSYTNPAVAA TSANL

Genular Protein ID: 4247100401

Symbol: Q7Z538_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7Z538

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 RefSeq 1 SAM 2

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 158
  • Mass: 16632
  • Checksum: 2FDFC9E30A99E41E
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTV VTGSGHASST PGGEKETSAT QRSSVLSSTE KNAIPAPTTT 
KSCRETFLKC FCRFINKGVF WASPILSSVW GWGARLGHRA AGAGLCSGCA GHCLSHCLGC 
LSVPPKELRA AGHLSSPGYL PSYERVPHLP HPWALCAP

Genular Protein ID: 3134337483

Symbol: A5YRV2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5YRV2

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 217
  • Mass: 23346
  • Checksum: A890B6A231FB3A22
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTG GEKETSATQR SSVPSSTEKN AIYKQGGFLG LSNIKFRPGS 
VVVQLTLAFR EGTINVHDVE TQFNQYKTEA ASRYNLTISD VSVSDVPFPF SAQSGAGVPG 
WGIALLVLVC VLVALAIVYL IALAVCQCRR KNYGQLDIFP ARDTYHPMSE YPTYHTHGRY 
VPPSSTDRSP YEKVSAGNGG SSLSYTNPAV AATSANL

Genular Protein ID: 1116783060

Symbol: Q7Z551_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7Z551

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 RefSeq 1 SAM 2

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 150
  • Mass: 16223
  • Checksum: 99A1BD4C2504A0FF
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTV VTGSGHASST PGGEKETSAT QRSSVPSSTE KNAFNSSLED 
PSTDYYQELQ RDISEMAVCQ CRRKNYGQLD IFPARDTYHP MSEYPTYHTH GRYAPPSSTD 
RSPYEKVSAG NGGSSLSYTN PAVAATSANL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.