Details for: MUC1

Gene ID: 4582

Gene Type:  Protein-coding  - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.

Symbol: MUC1

Ensembl ID: ENSG00000185499

Description: mucin 1, cell surface associated

Cell Significance Landscape

Associated with

Significant Cells

Cell Significance Index (CSI) scores for the chosen context(s)

  • fallopian tube secretory epithelial cell CL4030006
    CSI 61.37
    rCSI 59.08%
    PRS 89.27
  • nasal mucosa goblet cell CL0002480
    CSI 51.62
    rCSI 59.87%
    PRS 91.13
  • epithelial cell of lower respiratory tract CL0002632
    CSI 43.46
    rCSI 33.69%
    PRS 93.06
  • mucous neck cell CL0000651
    CSI 39.06
    rCSI 56.3%
    PRS 93.15
  • multi-ciliated epithelial cell CL0005012
    CSI 36.88
    rCSI 36.8%
    PRS 85.32
  • foveolar cell of stomach CL0002179
    CSI 33.43
    rCSI 71.15%
    PRS 92.67
  • duct epithelial cell CL0000068
    CSI 32.73
    rCSI 47.89%
    PRS 93.85
  • pulmonary alveolar type 2 cell CL0002063
    CSI 32.64
    rCSI 50.63%
    PRS 91.54
  • tracheal goblet cell CL1000329
    CSI 25.62
    rCSI 55.94%
    PRS 92.89
  • goblet cell CL0000160
    CSI 22.27
    rCSI 21.04%
    PRS 88.48
  • club cell CL0000158
    CSI 22.12
    rCSI 32.4%
    PRS 86.39
  • renal alpha-intercalated cell CL0005011
    CSI 20.72
    rCSI 27.7%
    PRS 93.72
  • secretory cell CL0000151
    CSI 19.97
    rCSI 20.84%
    PRS 89.59
  • squamous epithelial cell CL0000076
    CSI 19.29
    rCSI 45.78%
    PRS 87.97
  • dendritic cell CL0000451
    CSI 19.19
    rCSI 23.65%
    PRS 90.1
  • respiratory suprabasal cell CL4033048
    CSI 18.44
    rCSI 23.65%
    PRS 92.25
  • renal beta-intercalated cell CL0002201
    CSI 18.03
    rCSI 42.97%
    PRS 90.79
  • colon goblet cell CL0009039
    CSI 18.02
    rCSI 42.84%
    PRS 92.34
  • lung ciliated cell CL1000271
    CSI 17.73
    rCSI 20.5%
    PRS 85.35
  • ionocyte CL0005006
    CSI 17.59
    rCSI 18.86%
    PRS 91.94
  • pulmonary ionocyte CL0017000
    CSI 16.88
    rCSI 20.54%
    PRS 93.92
  • epithelial cell of proximal tubule CL0002306
    CSI 16.73
    rCSI 40.87%
    PRS 84.28
  • renal interstitial pericyte CL1001318
    CSI 16.3
    rCSI 44.93%
    PRS 88.03
  • epithelial cell of lung CL0000082
    CSI 15.9
    rCSI 13.18%
    PRS 91.47
  • M cell of gut CL0000682
    CSI 15.87
    rCSI 16.86%
    PRS 92.68
  • colon epithelial cell CL0011108
    CSI 15.78
    rCSI 16.53%
    PRS 88.45
  • pancreatic acinar cell CL0002064
    CSI 15.61
    rCSI 20.75%
    PRS 93.4
  • intestine goblet cell CL0019031
    CSI 15.26
    rCSI 13.55%
    PRS 88.21
  • enterocyte CL0000584
    CSI 14.16
    rCSI 22.83%
    PRS 87.7
  • deuterosomal cell CL4033044
    CSI 13.69
    rCSI 46.3%
    PRS 85.79
  • kidney collecting duct principal cell CL1001431
    CSI 12.94
    rCSI 65.12%
    PRS 86
  • conjunctival epithelial cell CL1000432
    CSI 12.82
    rCSI 19.58%
    PRS 89.82
  • ciliated epithelial cell CL0000067
    CSI 12.74
    rCSI 11.2%
    PRS 82.32
  • bronchial goblet cell CL1000312
    CSI 12.71
    rCSI 50.8%
    PRS 93.63
  • acinar cell CL0000622
    CSI 11.93
    rCSI 17.5%
    PRS 95.3
  • ciliated cell CL0000064
    CSI 11.46
    rCSI 18.56%
    PRS 85.11
  • respiratory basal cell CL0002633
    CSI 11.4
    rCSI 11.8%
    PRS 92.23
  • kidney interstitial alternatively activated macrophage CL1000695
    CSI 11.21
    rCSI 29.22%
    PRS 91.96
  • epithelial cell CL0000066
    CSI 10.8
    rCSI 16.59%
    PRS 79.3
  • BEST4+ enteroycte CL4030026
    CSI 10.57
    rCSI 13.15%
    PRS 90.49
  • mononuclear phagocyte CL0000113
    CSI 10.41
    rCSI 22.92%
    PRS 92.8
  • lung neuroendocrine cell CL1000223
    CSI 10.33
    rCSI 15.27%
    PRS 92.3
  • mucus secreting cell CL0000319
    CSI 9.92
    rCSI 15.76%
    PRS 94.77
  • kidney loop of Henle thin ascending limb epithelial cell CL1001107
    CSI 9.72
    rCSI 25.12%
    PRS 88
  • enterocyte of epithelium of large intestine CL0002071
    CSI 9.57
    rCSI 50.24%
    PRS 92.43
  • lung secretory cell CL1000272
    CSI 9.57
    rCSI 23.68%
    PRS 91.29
  • podocyte CL0000653
    CSI 9.33
    rCSI 41.44%
    PRS 91.02
  • enteroendocrine cell CL0000164
    CSI 9.26
    rCSI 12.66%
    PRS 89.2
  • transit amplifying cell of colon CL0009011
    CSI 9.15
    rCSI 10.75%
    PRS 90.69
  • tracheobronchial serous cell CL0019001
    CSI 8.46
    rCSI 36.53%
    PRS 92.88
  • kidney collecting duct intercalated cell CL1001432
    CSI 8.36
    rCSI 59.7%
    PRS 86.73
  • renal principal cell CL0005009
    CSI 8.35
    rCSI 21.7%
    PRS 89.94
  • CD1c-positive myeloid dendritic cell CL0002399
    CSI 8.16
    rCSI 9.85%
    PRS 94.85
  • ciliated columnar cell of tracheobronchial tree CL0002145
    CSI 8
    rCSI 18.25%
    PRS 83.98
  • respiratory hillock cell CL4030023
    CSI 7.62
    rCSI 13.59%
    PRS 94.32
  • myofibroblast cell CL0000186
    CSI 6.72
    rCSI 9.31%
    PRS 87.58
  • luminal epithelial cell of mammary gland CL0002326
    CSI 6.69
    rCSI 12.16%
    PRS 95.08
  • paneth cell CL0000510
    CSI 6.63
    rCSI 9.79%
    PRS 95.45
  • P/D1 enteroendocrine cell CL0002268
    CSI 6.53
    rCSI 35.55%
    PRS 92.94
  • brush cell of tracheobronchial tree CL0002075
    CSI 6.44
    rCSI 19.12%
    PRS 95.75
  • respiratory goblet cell CL0002370
    CSI 6.4
    rCSI 69.62%
    PRS 93.32
  • IgA plasma cell CL0000987
    CSI 6.38
    rCSI 6.53%
    PRS 92.32
  • stem cell CL0000034
    CSI 6.36
    rCSI 6.14%
    PRS 86.66
  • peptic cell CL0000155
    CSI 6.31
    rCSI 62.03%
    PRS 94.45
  • glandular epithelial cell CL0000150
    CSI 5.94
    rCSI 15.63%
    PRS 96.33
  • serous secreting cell CL0000313
    CSI 5.67
    rCSI 28.69%
    PRS 94.84
  • luminal cell of prostate epithelium CL0002340
    CSI 5.62
    rCSI 30.21%
    PRS 94.31
  • transit amplifying cell CL0009010
    CSI 5.25
    rCSI 8.03%
    PRS 93.81
  • pulmonary alveolar type 1 cell CL0002062
    CSI 5.1
    rCSI 29.43%
    PRS 87.8
  • stratified epithelial cell CL0000079
    CSI 4.36
    rCSI 26.92%
    PRS 93.3
  • small intestine goblet cell CL1000495
    CSI 3.68
    rCSI 8.07%
    PRS 92.86
  • mammary gland epithelial cell CL0002327
    CSI 3.64
    rCSI 12.78%
    PRS 94.36
  • kidney loop of Henle thick ascending limb epithelial cell CL1001106
    CSI 3.64
    rCSI 31.42%
    PRS 85.48
  • lung goblet cell CL1000143
    CSI 3.6
    rCSI 40.21%
    PRS 94.38
  • kidney loop of Henle thin descending limb epithelial cell CL1001111
    CSI 3.51
    rCSI 4.97%
    PRS 88.61
  • brush cell CL0002204
    CSI 3.44
    rCSI 6.81%
    PRS 93.43
  • kidney connecting tubule epithelial cell CL1000768
    CSI 3.23
    rCSI 8.18%
    PRS 84.61
  • tracheobronchial goblet cell CL0019003
    CSI 2.55
    rCSI 41.05%
    PRS 90.26
  • paneth cell of epithelium of small intestine CL1000343
    CSI 2.08
    rCSI 5.82%
    PRS 93.58
  • kidney distal convoluted tubule epithelial cell CL1000849
    CSI 1.9
    rCSI 20.13%
    PRS 86.85
  • kidney epithelial cell CL0002518
    CSI 1.73
    rCSI 3.31%
    PRS 96.96
  • intestinal crypt stem cell of colon CL0009043
    CSI 1.72
    rCSI 12.93%
    PRS 94.83
  • intestinal crypt stem cell of small intestine CL0009017
    CSI 1.69
    rCSI 4.56%
    PRS 92.73
  • macula densa epithelial cell CL1000850
    CSI 1.58
    rCSI 22.59%
    PRS 88.21
  • kidney connecting tubule principal cell CL4030018
    CSI 1.5
    rCSI 10.87%
    PRS 90.06
  • transit amplifying cell of small intestine CL0009012
    CSI 1.49
    rCSI 6.55%
    PRS 93.7
  • basal cell of epithelium of trachea CL1000348
    CSI 1.4
    rCSI 9.85%
    PRS 91.39
  • pancreatic ductal cell CL0002079
    CSI 1.35
    rCSI 2.62%
    PRS 92.2
  • alveolar macrophage CL0000583
    CSI 1.16
    rCSI 1.91%
    PRS 92.29
  • respiratory epithelial cell CL0002368
    CSI 0.84
    rCSI 5.2%
    PRS 98
  • epithelial cell of esophagus CL0002252
    CSI 0.54
    rCSI 5.31%
    PRS 89.8

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration

Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.

Comma-separated if multiple.
Comma-separated if multiple.
Legend:
  • Query Gene
  • Node Color (Target Cell CSI, relative to current network):
    • Very High
    • High
    • Medium
    • Low
    • Very Low
    • CSI N/A
  • Node Size: Proportional to Target Cell CSI magnitude
  • STRING PPI Edge
  • Shared Pathway Edge (ONTOLOGY)

Loading network (please wait)...

Other Information

This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.

## Summary [MUC1](/details-gene/4582) is a protein-coding gene located on chromosome 1q22 that encodes Mucin-1, a large, heavily glycosylated transmembrane protein. Primarily known as a cell surface associated mucin, [MUC1](/details-gene/4582) is a key component of the apical surface of most secretory epithelial cells, where it is thought to play a protective and lubricating role. The initial characterization of this gene revealed a highly polymorphic structure due to a variable number of tandem repeats (VNTR) in its coding sequence [Link](https://doi.org/10.1016/s0006-291x(05)80888-5). Beyond its barrier function, functional annotation suggests [MUC1](/details-gene/4582) is involved in intracellular signaling pathways, including DNA damage response and transcriptional regulation. Its expression is particularly prominent in various mucosal and glandular tissues, including the fallopian tube, respiratory tract, and stomach. Clinically, [MUC1](/details-gene/4582) is well-established as a tumor-associated antigen, with aberrant expression and glycosylation linked to various carcinomas ([158340](https://omim.org/entry/158340)). ## Cellular Roles and Expression Landscape **Overall**, the expression profile of [MUC1](/details-gene/4582) demonstrates its critical role in mucosal and glandular epithelial tissues. The gene shows the highest significance in secretory and protective cell types, establishing it as a defining marker for these lineages. Its most significant expression is observed in `[fallopian tube secretory epithelial cell](/details-cell/CL4030006)` (CSI: 61.37), `[nasal mucosa goblet cell](/details-cell/CL0002480)` (CSI: 51.62), and `[epithelial cell of lower respiratory tract](/details-cell/CL0002632)` (CSI: 43.46). This pattern extends to other mucus-producing cells such as `[mucous neck cell](/details-cell/CL0000651)` and `[foveolar cell of stomach](/details-cell/CL0002179)`, underscoring its general function in forming protective epithelial barriers. The gene's significance is also high in other secretory and ductal cells, including `[duct epithelial cell](/details-cell/CL0000068)` and `[pulmonary alveolar type 2 cell](/details-cell/CL0002063)`, suggesting a conserved role across diverse organ systems. While predominantly an epithelial marker, its notable significance in `[dendritic cell](/details-cell/CL0000451)` (CSI: 19.19) suggests a potential secondary role in the immune system, possibly in antigen presentation or immune modulation at mucosal surfaces. The consistent and high expression across these varied epithelial subtypes highlights [MUC1](/details-gene/4582) as a fundamental component of the body's first line of defense. ## Pathways and Molecular Function The molecular functions of [MUC1](/details-gene/4582) are multifaceted, extending beyond its structural role at the `[apical plasma membrane](/details-cell/GO:0016324)`. The protein is heavily involved in post-translational modifications, particularly `[O-linked glycosylation of mucins](/details-pathway/R-HSA-913709)`, a process critical for its function and one that is frequently altered in disease states. Its participation in `[Immune system](/details-pathway/R-HSA-168256)` pathways, including `[Cytokine signaling in immune system](/details-pathway/R-HSA-1280215)` and `[Interleukin-4 and interleukin-13 signaling](/details-pathway/R-HSA-6785807)`, aligns with its expression in dendritic cells and its role as an interface between the epithelium and the immune system. Intriguingly, Gene Ontology annotations indicate a nuclear function for [MUC1](/details-gene/4582). The protein is found in the `[nucleus](/details-cell/GO:0005634)` and `[chromatin](/details-cell/GO:0000785)`, where it exhibits `[p53 binding](/details-cell/GO:0002039)` activity and functions as a `[transcription coregulator](/details-cell/GO:0003712)`. This is consistent with its involvement in the `[Dna damage response, signal transduction by p53 class mediator](/details-pathway/GO:0030330)`. This dual localization suggests that [MUC1](/details-gene/4582) may function as a sensor at the cell surface that, upon specific stimuli, can translocate its cytoplasmic tail to the nucleus to directly influence gene expression and cell fate decisions. The existence of multiple protein isoforms generated by alternative splicing may explain these diverse functions [Link](https://doi.org/10.1007/s00262-012-1325-2). ## Research Directions The dual role of [MUC1](/details-gene/4582) as both a protective barrier protein and an intracellular signaling molecule, particularly in the context of cancer, presents several avenues for future research. Its established association with carcinomas ([158340](https://omim.org/entry/158340)) makes understanding its pathological mechanisms a priority. **Proposed Hypotheses:** 1. The cytoplasmic tail of [MUC1](/details-gene/4582), upon cleavage in response to cellular stress or oncogenic signaling, translocates to the nucleus where it binds p53. This interaction may competitively inhibit p53's tumor-suppressive functions, such as apoptosis induction (`[GO:1902166](/details-pathway/GO:1902166)`), thereby promoting cancer cell survival. 2. Aberrant glycosylation of the [MUC1](/details-gene/4582) extracellular domain in tumor cells masks integrin binding sites, leading to a `[negative regulation of cell adhesion mediated by integrin](/details-pathway/GO:0033629)`. This loss of adhesion contributes directly to increased cell motility and metastatic potential. **Experimental Approach:** To test the first hypothesis regarding the nuclear function of [MUC1](/details-gene/4582), a series of experiments could be conducted in a MUC1-positive cancer cell line (e.g., breast or pancreatic cancer). Following induction of DNA damage with a genotoxic agent, co-immunoprecipitation using an antibody against the [MUC1](/details-gene/4582) cytoplasmic tail could be performed on nuclear extracts, followed by Western blotting for p53 to confirm a direct interaction. Subsequently, a CRISPR-Cas9 system could be used to generate cell lines expressing only a truncated form of [MUC1](/details-gene/4582) lacking the cytoplasmic tail. Comparing the DNA damage response, cell cycle arrest, and apoptosis rates in these knockout cells versus wild-type cells would elucidate the functional consequence of the MUC1-p53 interaction. **Therapeutic Potential:** Given its high expression on the surface of many carcinomas and its more restricted expression in healthy tissues, [MUC1](/details-gene/4582) is a highly attractive target for cancer therapy. Its extracellular domain makes it accessible to antibody-based therapeutics. Inhibition of [MUC1](/details-gene/4582) signaling or targeted destruction of MUC1-expressing cells would be the primary therapeutic strategy. It is a prime candidate for the development of antibody-drug conjugates (ADCs), CAR-T cell therapies, and therapeutic vaccines designed to elicit an immune response against its tumor-specific glycoforms.

Genular Protein ID: 3885427404

Symbol: MUC1_HUMAN

Name: Mucin-1

UniProtKB Accession Codes:

P15941 A5YRV1 A6ZID9 A6ZIE0 B1AVQ8 B1AVR0 B6ECA1 E7ESE5 E7EUG9 P13931 P15942 P17626 Q0VAP5 Q0VAP6 Q14128 Q14876 Q16437 Q16442 Q16615 Q6S4Y3 Q7Z547 Q7Z548 Q7Z550 Q7Z552 Q9BXA4 Q9UE75 Q9UE76 Q9UQL1 Q9Y4J2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 7 CPTAC 4 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 2 EMBL 40 Ensembl 9 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 7 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MEROPS 1 MIM 4 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 18 PDBsum 18 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 16 Pumba 1 RNAct 1 Reactome 7 RefSeq 20 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2394722

Title: Cloning and sequencing of a human pancreatic tumor mucin cDNA.

PubMed ID: 2394722

DOI: 10.1016/s0021-9258(18)77255-4

PubMed ID: 2318825

Title: Episialin, a carcinoma-associated mucin, is generated by a polymorphic gene encoding splice variants with alternative amino termini.

PubMed ID: 2318825

DOI: 10.1016/s0021-9258(19)39399-8

PubMed ID: 1697589

Title: Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.

PubMed ID: 1697589

DOI: 10.1016/s0021-9258(18)77254-2

PubMed ID: 2268309

Title: Structure and expression of the human polymorphic epithelial mucin gene: an expressed VNTR unit.

PubMed ID: 2268309

DOI: 10.1016/s0006-291x(05)80888-5

PubMed ID: 2351132

Title: Human epithelial tumor antigen cDNA sequences. Differential splicing may generate multiple protein forms.

PubMed ID: 2351132

DOI: 10.1111/j.1432-1033.1990.tb15511.x

PubMed ID: 2112460

Title: A transcribed gene, containing a variable number of tandem repeats, codes for a human epithelial tumor antigen. cDNA cloning, expression of the transfected gene and over-expression in breast cancer tissue.

PubMed ID: 2112460

DOI: 10.1111/j.1432-1033.1990.tb15512.x

PubMed ID: 1688329

Title: Isolation and characterization of an expressed hypervariable gene coding for a breast-cancer-associated antigen.

PubMed ID: 1688329

DOI: 10.1016/0378-1119(90)90242-j

PubMed ID: 7925397

Title: Characterization and molecular cloning of a novel MUC1 protein, devoid of tandem repeats, expressed in human breast cancer tissue.

PubMed ID: 7925397

DOI: 10.1111/j.1432-1033.1994.00787.x

PubMed ID: 9212228

Title: Comparison of MUC-1 mucin expression in epithelial and non-epithelial cancer cell lines and demonstration of a new short variant form (MUC-1/Z).

PubMed ID: 9212228

DOI: 10.1002/(sici)1097-0215(19970703)72:1<87::aid-ijc13>3.0.co;2-7

PubMed ID: 15623537

Title: A novel protein derived from the MUC1 gene by alternative splicing and frameshifting.

PubMed ID: 15623537

DOI: 10.1074/jbc.m406943200

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

PubMed ID: 15969018

Title: Soluble expression of peptide containing MUC1/Y-specific epitope in Escherichia coli and preparation of the antibody.

PubMed ID: 15969018

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3417635

Title: A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats.

PubMed ID: 3417635

DOI: 10.1016/s0021-9258(18)37632-4

PubMed ID: 2597151

Title: Sequence analysis of the 5' region of the human DF3 breast carcinoma-associated antigen gene.

PubMed ID: 2597151

DOI: 10.1016/s0006-291x(89)80014-2

PubMed ID: 8608966

Title: Preoperative diagnosis of thyroid papillary carcinoma by reverse transcriptase polymerase chain reaction of the MUC1 gene.

PubMed ID: 8608966

DOI: 10.1002/(sici)1097-0215(19960328)66:1<55::aid-ijc10>3.0.co;2-a

PubMed ID: 8604237

Title: Mucin mRNA expression in lung adenocarcinoma cell lines and tissues.

PubMed ID: 8604237

DOI: 10.1159/000227547

PubMed ID: 11341784

Title: Identification of MUC1 proteolytic cleavage sites in vivo.

PubMed ID: 11341784

DOI: 10.1006/bbrc.2001.4775

PubMed ID: 15987679

Title: The MUC1 SEA module is a self-cleaving domain.

PubMed ID: 15987679

DOI: 10.1074/jbc.m506047200

PubMed ID: 10373415

Title: High density O-glycosylation on tandem repeat peptide from secretory MUC1 of T47D breast cancer cells.

PubMed ID: 10373415

DOI: 10.1074/jbc.274.26.18165

PubMed ID: 7988707

Title: Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins. Cytokine receptor-like molecules.

PubMed ID: 7988707

DOI: 10.1016/0014-5793(94)01251-2

PubMed ID: 7664271

Title: Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein.

PubMed ID: 7664271

PubMed ID: 7744025

Title: Studies on the order and site specificity of GalNAc transfer to MUC1 tandem repeats by UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase from milk or mammary carcinoma cells.

PubMed ID: 7744025

DOI: 10.1111/j.1432-1033.1995.tb20448.x

PubMed ID: 9139698

Title: Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion.

PubMed ID: 9139698

DOI: 10.1074/jbc.272.19.12492

PubMed ID: 9312074

Title: Localization of O-glycosylation sites on glycopeptide fragments from lactation-associated MUC1. All putative sites within the tandem repeat are glycosylation targets in vivo.

PubMed ID: 9312074

DOI: 10.1074/jbc.272.40.24780

PubMed ID: 9536947

Title: Developmental expression of mucin genes in the human gastrointestinal system.

PubMed ID: 9536947

DOI: 10.1136/gut.42.2.220

PubMed ID: 9597769

Title: Localization of O-glycosylation sites of MUC1 tandem repeats by QTOF ESI mass spectrometry.

PubMed ID: 9597769

DOI: 10.1002/(sici)1096-9888(199804)33:4<358::aid-jms642>3.0.co;2-3

PubMed ID: 9819408

Title: Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin.

PubMed ID: 9819408

DOI: 10.1128/mcb.18.12.7216

PubMed ID: 10197628

Title: The breast cancer-associated MUC1 gene generates both a receptor and its cognate binding protein.

PubMed ID: 10197628

PubMed ID: 11173916

Title: MUC1 mucin core protein binds to the domain 1 of ICAM-1.

PubMed ID: 11173916

DOI: 10.1159/000051917

PubMed ID: 11118479

Title: Mucin MUC1 is seen in cell surface protrusions together with ezrin in immunoelectron tomography and is concentrated at tips of filopodial protrusions in MCF-7 breast carcinoma cells.

PubMed ID: 11118479

DOI: 10.1177/002215540104900107

PubMed ID: 11152665

Title: The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin.

PubMed ID: 11152665

DOI: 10.1074/jbc.c000754200

PubMed ID: 11350974

Title: Identification and topology of variant sequences within individual repeat domains of the human epithelial tumor mucin MUC1.

PubMed ID: 11350974

DOI: 10.1074/jbc.m103187200

PubMed ID: 11483589

Title: The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin.

PubMed ID: 11483589

DOI: 10.1074/jbc.c100359200

PubMed ID: 11877440

Title: Protein kinase C delta regulates function of the DF3/MUC1 carcinoma antigen in beta-catenin signaling.

PubMed ID: 11877440

DOI: 10.1074/jbc.m200436200

PubMed ID: 14521915

Title: Identification of four sites of stimulated tyrosine phosphorylation in the MUC1 cytoplasmic tail.

PubMed ID: 14521915

DOI: 10.1016/j.bbrc.2003.09.030

PubMed ID: 12750561

Title: DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7.

PubMed ID: 12750561

DOI: 10.4161/cbt.2.2.282

PubMed ID: 14688481

Title: MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation.

PubMed ID: 14688481

PubMed ID: 12441351

Title: Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding.

PubMed ID: 12441351

DOI: 10.1074/jbc.m208326200

PubMed ID: 12832415

Title: Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin.

PubMed ID: 12832415

DOI: 10.1074/jbc.m304333200

PubMed ID: 12939402

Title: Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein.

PubMed ID: 12939402

PubMed ID: 15471854

Title: MUC1 membrane trafficking is modulated by multiple interactions.

PubMed ID: 15471854

DOI: 10.1074/jbc.m409360200

PubMed ID: 15710329

Title: Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response.

PubMed ID: 15710329

DOI: 10.1016/j.ccr.2005.01.008

PubMed ID: 16288032

Title: MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin.

PubMed ID: 16288032

DOI: 10.1158/0008-5472.can-05-2474

PubMed ID: 15972891

Title: Transmembrane and secreted MUC1 probes show trafficking-dependent changes in O-glycan core profiles.

PubMed ID: 15972891

DOI: 10.1093/glycob/cwi099

PubMed ID: 15513966

Title: MUC1 (CD227) interacts with lck tyrosine kinase in Jurkat lymphoma cells and normal T cells.

PubMed ID: 15513966

DOI: 10.1189/jlb.0604333

PubMed ID: 16507569

Title: Recycling of MUC1 is dependent on its palmitoylation.

PubMed ID: 16507569

DOI: 10.1074/jbc.m512996200

PubMed ID: 16427018

Title: MUC1 oncoprotein stabilizes and activates estrogen receptor alpha.

PubMed ID: 16427018

DOI: 10.1016/j.molcel.2005.11.030

PubMed ID: 17524503

Title: MUC1 inhibits cell proliferation by a beta-catenin-dependent mechanism.

PubMed ID: 17524503

DOI: 10.1016/j.bbamcr.2007.04.009

PubMed ID: 17308127

Title: Human mucin 1 oncoprotein represses transcription of the p53 tumor suppressor gene.

PubMed ID: 17308127

DOI: 10.1158/0008-5472.can-06-3063

PubMed ID: 17545600

Title: Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells.

PubMed ID: 17545600

DOI: 10.1158/0008-5472.can-06-4647

PubMed ID: 16983337

Title: MUC1 is a novel regulator of ErbB1 receptor trafficking.

PubMed ID: 16983337

DOI: 10.1038/sj.onc.1209976

PubMed ID: 20816948

Title: CA 15-3: uses and limitation as a biomarker for breast cancer.

PubMed ID: 20816948

DOI: 10.1016/j.cca.2010.08.039

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23396133

Title: Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.

PubMed ID: 23396133

DOI: 10.1038/ng.2543

PubMed ID: 16585136

Title: N-glycosylation of the MUC1 mucin in epithelial cells and secretions.

PubMed ID: 16585136

DOI: 10.1093/glycob/cwj110

PubMed ID: 35504880

Title: Structural basis for the synthesis of the core 1 structure by C1GalT1.

PubMed ID: 35504880

DOI: 10.1038/s41467-022-29833-0

Sequence Information:

  • Length: 1255
  • Mass: 122102
  • Checksum: 5E28DFC4C20D9A82
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTV VTGSGHASST PGGEKETSAT QRSSVPSSTE KNAVSMTSSV 
LSSHSPGSGS STTQGQDVTL APATEPASGS AATWGQDVTS VPVTRPALGS TTPPAHDVTS 
APDNKPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS 
APDTRPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDNRPALGS TAPPVHNVTS 
ASGSASGSAS TLVHNGTSAR ATTTPASKST PFSIPSHHSD TPTTLASHST KTDASSTHHS 
SVPPLTSSNH STSPQLSTGV SFFFLSFHIS NLQFNSSLED PSTDYYQELQ RDISEMFLQI 
YKQGGFLGLS NIKFRPGSVV VQLTLAFREG TINVHDVETQ FNQYKTEAAS RYNLTISDVS 
VSDVPFPFSA QSGAGVPGWG IALLVLVCVL VALAIVYLIA LAVCQCRRKN YGQLDIFPAR 
DTYHPMSEYP TYHTHGRYVP PSSTDRSPYE KVSAGNGGSS LSYTNPAVAA TSANL

Genular Protein ID: 2835380164

Symbol: A6ZIE6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6ZIE6

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 177
  • Mass: 19116
  • Checksum: 2C60A683BB1643A0
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NALSTGVSFF FLSFHISNLQ FNSSLEDPST DYYQELQRDI SEMAVCQCRR KNYGQLDIFP 
ARDTYHPMSE YPTYHTHGRY VPPSSTDRSP YEKVSAGNGG SSLSYTNPAV AATSANL

Genular Protein ID: 3126720045

Symbol: A6ZID6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6ZID6

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 241
  • Mass: 25656
  • Checksum: F4AFFB0837464EE2
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAFLQIYKQG GFLGLSNIKF RPGSVVVQLT LAFREGTINV HDVETQFNQY ETEAASRYNL 
TISDVSVSDV PFPFSAQSGA GVPGWGIALL VLVCVLVALA IVYLIALAVC QCRRKNYGQL 
DIFPARDTYH PMSEYPTYHT HGRYVPPSST DRSPYEKVSA GNGGSSLSYT NPAVAATSAN 
L

Genular Protein ID: 2393977749

Symbol: A0A0A0MRB3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MRB3

Database IDs:

ARBA 12 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 2 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 241
  • Mass: 25655
  • Checksum: F919FE9E3F664EE2
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAFLQIYKQG GFLGLSNIKF RPGSVVVQLT LAFREGTINV HDVETQFNQY KTEAASRYNL 
TISDVSVSDV PFPFSAQSGA GVPGWGIALL VLVCVLVALA IVYLIALAVC QCRRKNYGQL 
DIFPARDTYH PMSEYPTYHT HGRYVPPSST DRSPYEKVSA GNGGSSLSYT NPAVAATSAN 
L

Genular Protein ID: 848665009

Symbol: A5YRU5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5YRU5

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 3 SMART 1 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 282
  • Mass: 30431
  • Checksum: 2E431D8053353D57
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NALSTGVSFF FLSFHISNLQ FNSSLEDPST DYYQELQRDI SEMFLQIYKQ GGFLGLSNIK 
FRPGSVVVQL TLAFREGTIN VHDVETQFNQ YKTEAASRYN LTISDVSVSD VPFPFSAQSG 
AGVPGWGIAL LVLVCVLVAL AIVYLIALAV CQCRRKNYGQ LDIFPARDTY HPMSEYPTYH 
THGRYVPPSS TDRSPYEKVS AGNGGSSLSY TNPAVAATSA NL

Genular Protein ID: 3413259241

Symbol: A0A384NPK6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A384NPK6

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 ExpressionAtlas 1 GO 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 RefSeq 1 SAM 2 SMR 1 VEuPathDB 1

Sequence Information:

  • Length: 159
  • Mass: 17090
  • Checksum: 2C3B69F515D73168
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAFNSSLEDP STDYYQELQR DISEMAVCQC RRKNYGQLDI FPARDTYHPM SEYPTYHTHG 
RYVPPSSTDR SPYEKVSAGN GGSSLSYTNP AVAATSANL

Genular Protein ID: 125996330

Symbol: A5YRU7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5YRU7

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 219
  • Mass: 23466
  • Checksum: C0DB674812B59BB5
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAFNSSLEDP STDYYQELQR DISEMFLQIY KQGGFLGLSN IKFRPGSVVV QLTLAFREGT 
INVHDVETQF NQYKTEAASR YNLTISDVSV WGWGARLGHR AAGAGLCSGC AGHCLSHCLG 
CLSVPPKELR AAGHLSSPGY LPSYERVPHL PHPWALCAP

Genular Protein ID: 943576806

Symbol: A6ZIE4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6ZIE4

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 1 GeneTree 1 HGNC 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 189
  • Mass: 20037
  • Checksum: C617B22043CAD95A
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAFNSSLEDP STDYYQELQR DISEMSGAGV PGWGIALLVL VCVLVALAIV YLIALAVCQC 
RRKNYGQLDI FPARDTYHPM SEYPTYHTHG RYVPPSSTDR SPYEKVSAGN GGSSLSYTNP 
AVAATSANL

Genular Protein ID: 1634703192

Symbol: A0A087X0L2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087X0L2

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 239
  • Mass: 25405
  • Checksum: 2D7880F01A8FD2BD
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAIPAPTTTK SCRETFLKWP GSVVVQLTLA FREGTINVHD VETQFNQYKT EAASRYNLTI 
SDVSVSDVPF PFSAQSGAGV PGWGIALLVL VCVLVALAIV YLIALAVCQC RRKNYGQLDI 
FPARDTYHPM SEYPTYHTHG RYVPPSSTDR SPYEKVSAGN GGSSLSYTNP AVAATSANL

Genular Protein ID: 4014158383

Symbol: B6ECB3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B6ECB3

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 RefSeq 1 SAM 3

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 212
  • Mass: 22395
  • Checksum: FF70E57FCE3318E9
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAIPAPTTTK SCRETFLKCF CRFINKGVFW ASPILSSVSD VPFPFSAQSG AGVPGWGIAL 
LVLVCVLVAL AIVYLIALAV CQCRRKNYGQ LDIFPARDTY HPMSEYPTYH THGRYVPPSS 
TDRSPYEKVS AGNGGSSLSY TNPAVAATSA NL

Genular Protein ID: 3646052366

Symbol: A6ZID7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6ZID7

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 RefSeq 1 SAM 3 SMR 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 239
  • Mass: 25378
  • Checksum: B47880EA33840BAC
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAIPAPTTTK SCRETFLKWP GSVVVQLTLA FREGTINVHD VETQFSQYKT EAASRYNLTI 
SDVSVSDVPF PFSAQSGAGV PGWGIALLVL VCVLVALAIV YLIALAVCQC RRKNYGQLDI 
FPARDTYHPM SEYPTYHTHG RYVPPSSTDR SPYEKVSAGN GGSSLSYTNP AVAATSANL

Genular Protein ID: 3024758077

Symbol: A5YRV0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5YRV0

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 238
  • Mass: 25267
  • Checksum: 253AFB230AE79A8D
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK 
NAIYKQGGFL GLSNIKFRPG SVVVQLTLAF REGTINVHDV ETQFNQYKTE AASRYNLTIS 
DVSVSDVPFP FSAQSGAGVP GWGIALLVLV CVLVALAIVY LIALAVCQCR RKNYGQLDIF 
PARDTYHPMS EYPTYHTHGR YVPPSSTDRS PYEKVSAGNG GSSLSYTNPA VAATSANL

Genular Protein ID: 1502339803

Symbol: A0A0C4DGW3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DGW3

Database IDs:

ARBA 12 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 2 MEROPS 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 1 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 475
  • Mass: 49224
  • Checksum: CB64D56690818614
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTV VTGSGHASST PGGEKETSAT QRSSVPSSTE KNAVSMTSSV 
LSSHSPGSGS STTQGQDVTL APATEPASGS AATWGQDVTS VPVTRPALGS TTPPAHDVTS 
APDNKPAPGS TAPPAHGVTS APDTRPAPGS TAPPAHGVTS APDNRPALGS TAPPVHNVTS 
ASGSASGSAS TLVHNGTSAR ATTTPASKST PFSIPSHHSD TPTTLASHST KTDASSTHHS 
TVPPLTSSNH STSPQLSTGV SFFFLSFHIS NLQFNSSLED PSTDYYQELQ RDISEMFLQI 
YKQGGFLGLS NIKFRPGSVV VQLTLAFREG TINVHDVETQ FNQYKTEAAS RYNLTISDVS 
VSDVPFPFSA QSGAGVPGWG IALLVLVCVL VALAIVYLIA LAVCQCRRKN YGQLDIFPAR 
DTYHPMSEYP TYHTHGRYVP PSSTDRSPYE KVSAGNGGSS LSYTNPAVAA TSANL

Genular Protein ID: 4247100401

Symbol: Q7Z538_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7Z538

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 RefSeq 1 SAM 2

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 158
  • Mass: 16632
  • Checksum: 2FDFC9E30A99E41E
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTV VTGSGHASST PGGEKETSAT QRSSVLSSTE KNAIPAPTTT 
KSCRETFLKC FCRFINKGVF WASPILSSVW GWGARLGHRA AGAGLCSGCA GHCLSHCLGC 
LSVPPKELRA AGHLSSPGYL PSYERVPHLP HPWALCAP

Genular Protein ID: 3134337483

Symbol: A5YRV2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5YRV2

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 217
  • Mass: 23346
  • Checksum: A890B6A231FB3A22
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTG GEKETSATQR SSVPSSTEKN AIYKQGGFLG LSNIKFRPGS 
VVVQLTLAFR EGTINVHDVE TQFNQYKTEA ASRYNLTISD VSVSDVPFPF SAQSGAGVPG 
WGIALLVLVC VLVALAIVYL IALAVCQCRR KNYGQLDIFP ARDTYHPMSE YPTYHTHGRY 
VPPSSTDRSP YEKVSAGNGG SSLSYTNPAV AATSANL

Genular Protein ID: 1116783060

Symbol: Q7Z551_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7Z551

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 RefSeq 1 SAM 2

Citations:

PubMed ID: 22941036

Title: Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms.

PubMed ID: 22941036

DOI: 10.1007/s00262-012-1325-2

Sequence Information:

  • Length: 150
  • Mass: 16223
  • Checksum: 99A1BD4C2504A0FF
  • Sequence:
    • MTPGTQSPFF LLLLLTVLTV VTGSGHASST PGGEKETSAT QRSSVPSSTE KNAFNSSLED 
PSTDYYQELQ RDISEMAVCQ CRRKNYGQLD IFPARDTYHP MSEYPTYHTH GRYAPPSSTD 
RSPYEKVSAG NGGSSLSYTN PAVAATSANL