Details for: MYO6

Gene ID: 4646

Symbol: MYO6

Ensembl ID: ENSG00000196586

Description: myosin VI

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 559.2586
    Cell Significance Index: -86.9900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 347.9294
    Cell Significance Index: -88.2500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 192.7465
    Cell Significance Index: -91.0000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 183.7506
    Cell Significance Index: -74.6500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 78.2514
    Cell Significance Index: -74.7100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 70.5459
    Cell Significance Index: -86.9800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 32.3309
    Cell Significance Index: -86.6100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 22.3261
    Cell Significance Index: -88.1000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 16.7003
    Cell Significance Index: -36.5500
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 6.4387
    Cell Significance Index: 39.6300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.4298
    Cell Significance Index: 487.4200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.4026
    Cell Significance Index: 22.1300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.1909
    Cell Significance Index: 238.3000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.0948
    Cell Significance Index: 57.0200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.0891
    Cell Significance Index: 108.8200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.0593
    Cell Significance Index: 371.2400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.8195
    Cell Significance Index: 223.7300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.7466
    Cell Significance Index: 90.7300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.7051
    Cell Significance Index: 611.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.6906
    Cell Significance Index: 126.0000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.4119
    Cell Significance Index: 1274.8200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.3917
    Cell Significance Index: 16.5900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.1065
    Cell Significance Index: 604.2900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.0683
    Cell Significance Index: 40.4500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.0361
    Cell Significance Index: 45.8300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.9555
    Cell Significance Index: 43.3100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9266
    Cell Significance Index: 183.8900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.9177
    Cell Significance Index: 43.1300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8770
    Cell Significance Index: 606.5500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.8306
    Cell Significance Index: 55.8500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.8131
    Cell Significance Index: 51.2500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.8096
    Cell Significance Index: 17.5400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5994
    Cell Significance Index: 76.8400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5053
    Cell Significance Index: 14.5600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3727
    Cell Significance Index: 236.6900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3146
    Cell Significance Index: 40.6500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2492
    Cell Significance Index: 469.2100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2439
    Cell Significance Index: 46.4100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2352
    Cell Significance Index: 5.1500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2235
    Cell Significance Index: 17.1500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1631
    Cell Significance Index: 27.8500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1197
    Cell Significance Index: 5.5800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1175
    Cell Significance Index: 51.9300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1012
    Cell Significance Index: 3.5500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0906
    Cell Significance Index: 8.9600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0612
    Cell Significance Index: 1.7100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0357
    Cell Significance Index: 16.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0226
    Cell Significance Index: 41.6400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0170
    Cell Significance Index: 12.4800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0157
    Cell Significance Index: 0.2000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0131
    Cell Significance Index: 20.1700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0015
    Cell Significance Index: -0.0400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0278
    Cell Significance Index: -37.8200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0452
    Cell Significance Index: -34.2100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0550
    Cell Significance Index: -40.7400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0578
    Cell Significance Index: -36.0700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0599
    Cell Significance Index: -8.7100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1061
    Cell Significance Index: -2.2600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.1074
    Cell Significance Index: -17.4700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1280
    Cell Significance Index: -72.1700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1382
    Cell Significance Index: -15.7800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1391
    Cell Significance Index: -19.1000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2142
    Cell Significance Index: -45.1100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2263
    Cell Significance Index: -11.8800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2621
    Cell Significance Index: -7.4800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2662
    Cell Significance Index: -76.6000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3116
    Cell Significance Index: -5.3400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3928
    Cell Significance Index: -22.0400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.4151
    Cell Significance Index: -42.4000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4209
    Cell Significance Index: -48.2200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4581
    Cell Significance Index: -6.2500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.4838
    Cell Significance Index: -56.3800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5901
    Cell Significance Index: -61.4400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.5997
    Cell Significance Index: -36.8600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.6066
    Cell Significance Index: -42.9000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.6336
    Cell Significance Index: -9.0200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.6610
    Cell Significance Index: -14.1300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.6959
    Cell Significance Index: -44.9000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.7376
    Cell Significance Index: -86.9900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.8097
    Cell Significance Index: -20.2400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.8711
    Cell Significance Index: -27.9000
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.8852
    Cell Significance Index: -11.4000
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.8975
    Cell Significance Index: -12.5500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.9135
    Cell Significance Index: -72.3500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.0597
    Cell Significance Index: -27.8700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.0667
    Cell Significance Index: -6.4400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1476
    Cell Significance Index: -70.3600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -1.1577
    Cell Significance Index: -16.6500
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.2310
    Cell Significance Index: -15.3500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.3427
    Cell Significance Index: -46.6600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.5120
    Cell Significance Index: -38.8700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.5944
    Cell Significance Index: -33.8400
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.6385
    Cell Significance Index: -20.6800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.7222
    Cell Significance Index: -54.8500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.7266
    Cell Significance Index: -56.5300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -1.7480
    Cell Significance Index: -40.3900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.7957
    Cell Significance Index: -52.8900
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -1.8117
    Cell Significance Index: -31.3300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -1.8891
    Cell Significance Index: -45.3100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -1.8936
    Cell Significance Index: -30.3800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** MYO6 is a hexameric protein, composed of six subunits, each containing a myosin motor domain. The protein exhibits a high degree of flexibility and can bind to actin filaments, either directly or indirectly, through its long N-terminal tail. The C-terminal myosin motor domain is responsible for its ATPase activity, which drives the movement of actin filaments. MYO6 is also capable of interacting with various proteins, including calmodulin, clathrin, and Rab GTPases, which are involved in endocytosis and vesicle-mediated transport. **Pathways and Functions** MYO6 plays a crucial role in various cellular processes, including: 1. **Actin filament organization**: MYO6 regulates the organization of actin filaments, which is essential for maintaining cellular structure and facilitating cell migration and division. 2. **Endocytosis**: MYO6 interacts with clathrin and Rab GTPases to regulate the formation and movement of clathrin-coated vesicles, which is essential for endocytic trafficking. 3. **Vesicle-mediated transport**: MYO6 regulates the movement of vesicles along actin filaments, which is essential for transporting proteins and lipids between different cellular compartments. 4. **Cell migration**: MYO6 is involved in regulating cellular migration, which is essential for various cellular processes, including wound healing and cancer metastasis. 5. **Neurotransmission**: MYO6 is expressed in neurons and plays a role in regulating synaptic plasticity and neurotransmitter release. **Clinical Significance** Dysregulation of MYO6 has been implicated in various diseases, including: 1. **Neurological disorders**: MYO6 mutations have been associated with neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease. 2. **Cancer**: MYO6 overexpression has been observed in various types of cancer, including breast cancer and lung cancer. 3. **Kidney disease**: MYO6 mutations have been associated with kidney disease, including focal segmental glomerulosclerosis and nephrotic syndrome. 4. **Hearing loss**: MYO6 mutations have been associated with hearing loss, particularly in the inner ear auditory receptor cells. In conclusion, MYO6 is a multifunctional protein that plays a crucial role in various cellular processes, including actin filament organization, endocytosis, and vesicle-mediated transport. Dysregulation of MYO6 has been implicated in various diseases, highlighting the importance of this gene in maintaining cellular homeostasis and overall health.

Genular Protein ID: 586736011

Symbol: MYO6_HUMAN

Name: Unconventional myosin-VI

UniProtKB Accession Codes:

Q9UM54 A6H8V4 E1P540 Q5TEM5 Q5TEM6 Q5TEM7 Q9BZZ7 Q9UEG2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 4 CTD 1 ChEBI 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 38 EMDB 2 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 47 Gene3D 7 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 6 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 PANTHER 2 PDB 8 PDBsum 8 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 5 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9259267

Title: Characterization of unconventional MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice.

PubMed ID: 9259267

DOI: 10.1093/hmg/6.8.1225

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16344560

Title: Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.

PubMed ID: 16344560

DOI: 10.1101/gr.4039406

PubMed ID: 9852149

Title: The localization of myosin VI at the Golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation.

PubMed ID: 9852149

DOI: 10.1083/jcb.143.6.1535

PubMed ID: 10519557

Title: Myosin VI is an actin-based motor that moves backwards.

PubMed ID: 10519557

DOI: 10.1038/46835

PubMed ID: 11447109

Title: Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis.

PubMed ID: 11447109

DOI: 10.1093/emboj/20.14.3676

PubMed ID: 11967127

Title: Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton.

PubMed ID: 11967127

DOI: 10.1034/j.1600-0854.2002.30503.x

PubMed ID: 15247260

Title: Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator.

PubMed ID: 15247260

DOI: 10.1074/jbc.m403141200

PubMed ID: 15044955

Title: A monomeric myosin VI with a large working stroke.

PubMed ID: 15044955

DOI: 10.1038/sj.emboj.7600180

PubMed ID: 16949370

Title: Nuclear myosin VI enhances RNA polymerase II-dependent transcription.

PubMed ID: 16949370

DOI: 10.1016/j.molcel.2006.07.005

PubMed ID: 16507995

Title: Myosin VI is a mediator of the p53-dependent cell survival pathway.

PubMed ID: 16507995

DOI: 10.1128/mcb.26.6.2175-2186.2006

PubMed ID: 18511944

Title: Long single alpha-helical tail domains bridge the gap between structure and function of myosin VI.

PubMed ID: 18511944

DOI: 10.1038/nsmb.1429

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23023224

Title: Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome.

PubMed ID: 23023224

DOI: 10.1038/ncb2589

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29467281

Title: The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

PubMed ID: 29467281

DOI: 10.15252/embr.201744884

PubMed ID: 11468689

Title: MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice, is mutated in autosomal dominant nonsyndromic hearing loss.

PubMed ID: 11468689

DOI: 10.1086/323156

PubMed ID: 12687499

Title: Mutations of MYO6 are associated with recessive deafness, DFNB37.

PubMed ID: 12687499

DOI: 10.1086/375122

PubMed ID: 15060111

Title: Novel association of hypertrophic cardiomyopathy, sensorineural deafness, and a mutation in unconventional myosin VI (MYO6).

PubMed ID: 15060111

DOI: 10.1136/jmg.2003.011973

PubMed ID: 31371777

Title: Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering.

PubMed ID: 31371777

DOI: 10.1038/s41467-019-11481-6

Sequence Information:

  • Length: 1294
  • Mass: 149691
  • Checksum: 3A8966E6864B8576
  • Sequence:
    • MEDGKPVWAP HPTDGFQMGN IVDIGPDSLT IEPLNQKGKT FLALINQVFP AEEDSKKDVE 
DNCSLMYLNE ATLLHNIKVR YSKDRIYTYV ANILIAVNPY FDIPKIYSSE AIKSYQGKSL 
GTRPPHVFAI ADKAFRDMKV LKMSQSIIVS GESGAGKTEN TKFVLRYLTE SYGTGQDIDD 
RIVEANPLLE AFGNAKTVRN NNSSRFGKFV EIHFNEKSSV VGGFVSHYLL EKSRICVQGK 
EERNYHIFYR LCAGASEDIR EKLHLSSPDN FRYLNRGCTR YFANKETDKQ ILQNRKSPEY 
LKAGSMKDPL LDDHGDFIRM CTAMKKIGLD DEEKLDLFRV VAGVLHLGNI DFEEAGSTSG 
GCNLKNKSAQ SLEYCAELLG LDQDDLRVSL TTRVMLTTAG GTKGTVIKVP LKVEQANNAR 
DALAKTVYSH LFDHVVNRVN QCFPFETSSY FIGVLDIAGF EYFEHNSFEQ FCINYCNEKL 
QQFFNERILK EEQELYQKEG LGVNEVHYVD NQDCIDLIEA KLVGILDILD EENRLPQPSD 
QHFTSAVHQK HKDHFRLTIP RKSKLAVHRN IRDDEGFIIR HFAGAVCYET TQFVEKNNDA 
LHMSLESLIC ESRDKFIREL FESSTNNNKD TKQKAGKLSF ISVGNKFKTQ LNLLLDKLRS 
TGASFIRCIK PNLKMTSHHF EGAQILSQLQ CSGMVSVLDL MQGGYPSRAS FHELYNMYKK 
YMPDKLARLD PRLFCKALFK ALGLNENDYK FGLTKVFFRP GKFAEFDQIM KSDPDHLAEL 
VKRVNHWLTC SRWKKVQWCS LSVIKLKNKI KYRAEACIKM QKTIRMWLCK RRHKPRIDGL 
VKVGTLKKRL DKFNEVVSVL KDGKPEMNKQ IKNLEISIDT LMAKIKSTMM TQEQIQKEYD 
ALVKSSEELL SALQKKKQQE EEAERLRRIQ EEMEKERKRR EEDEKRRRKE EEERRMKLEM 
EAKRKQEEEE RKKREDDEKR IQAEVEAQLA RQKEEESQQQ AVLEQERRDR ELALRIAQSE 
AELISDEAQA DLALRRSLDS YPVSKNDGTR PKMTPEQMAK EMSEFLSRGP AVLATKAAAG 
TKKYDLSKWK YAELRDTINT SCDIELLAAC REEFHRRLKV YHAWKSKNKK RNTETEQRAP 
KSVTDYDFAP FLNNSPQQNP AAQIPARQRE IEMNRQQRFF RIPFIRPADQ YKDPQSKKKG 
WWYAHFDGPW IARQMELHPD KPPILLVAGK DDMEMCELNL EETGLTRKRG AEILPRQFEE 
IWERCGGIQY LQNAIESRQA RPTYATAMLQ SLLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.