Details for: PPP1R12B
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 448.6798
Cell Significance Index: -69.7900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 277.9296
Cell Significance Index: -70.5000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 145.2589
Cell Significance Index: -68.5800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 136.3053
Cell Significance Index: -55.3800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 58.0366
Cell Significance Index: -55.4100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 57.7555
Cell Significance Index: -71.2100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 24.6672
Cell Significance Index: -66.0800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 18.0788
Cell Significance Index: -71.3400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 14.4751
Cell Significance Index: -31.6800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 7.6803
Cell Significance Index: 589.3800 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 6.7981
Cell Significance Index: 165.8700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 5.9697
Cell Significance Index: 153.4500 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 4.6052
Cell Significance Index: 57.9900 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 4.1034
Cell Significance Index: 60.5800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 3.6064
Cell Significance Index: 1636.8400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.6800
Cell Significance Index: 537.6100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 2.4560
Cell Significance Index: 165.1400 - Cell Name: preadipocyte (CL0002334)
Fold Change: 2.2570
Cell Significance Index: 44.0500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.2458
Cell Significance Index: 805.5200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 2.1747
Cell Significance Index: 82.3500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.1427
Cell Significance Index: 425.2300 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 2.1170
Cell Significance Index: 50.7700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 2.0736
Cell Significance Index: 91.7200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 2.0387
Cell Significance Index: 125.3100 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 1.9634
Cell Significance Index: 31.6800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.6539
Cell Significance Index: 1143.9100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.5401
Cell Significance Index: 43.0400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.4235
Cell Significance Index: 79.8800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.0684
Cell Significance Index: 111.2400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.0073
Cell Significance Index: 1896.5800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.8788
Cell Significance Index: 86.9400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8260
Cell Significance Index: 745.7800 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.7911
Cell Significance Index: 16.9100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.6097
Cell Significance Index: 387.2500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5222
Cell Significance Index: 23.6700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.5007
Cell Significance Index: 8.5800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.4711
Cell Significance Index: 57.9200 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: 0.4330
Cell Significance Index: 1.8900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3972
Cell Significance Index: 71.6000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3943
Cell Significance Index: 64.1300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2346
Cell Significance Index: 6.7600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2044
Cell Significance Index: 22.2400 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.1750
Cell Significance Index: 2.1700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1418
Cell Significance Index: 261.5400 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.1358
Cell Significance Index: 0.9200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.1355
Cell Significance Index: 208.5400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1203
Cell Significance Index: 163.5800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1143
Cell Significance Index: 50.5200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0808
Cell Significance Index: 1.7500 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0664
Cell Significance Index: 8.5100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0588
Cell Significance Index: 2.0700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.0266
Cell Significance Index: 0.7600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0133
Cell Significance Index: 7.2700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0049
Cell Significance Index: 0.1300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0056
Cell Significance Index: -0.7700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.0484
Cell Significance Index: -9.2200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0722
Cell Significance Index: -52.9300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0808
Cell Significance Index: -59.8800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0843
Cell Significance Index: -63.7800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1214
Cell Significance Index: -68.4900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1249
Cell Significance Index: -77.9900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.1283
Cell Significance Index: -7.7000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1294
Cell Significance Index: -6.0800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1389
Cell Significance Index: -9.6100 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.1516
Cell Significance Index: -2.1200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1731
Cell Significance Index: -25.1700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2121
Cell Significance Index: -61.0200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.2397
Cell Significance Index: -40.9300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2728
Cell Significance Index: -14.1700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3171
Cell Significance Index: -36.9600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.3559
Cell Significance Index: -36.3600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3600
Cell Significance Index: -75.8200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.3843
Cell Significance Index: -27.1800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.3901
Cell Significance Index: -18.1900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.4087
Cell Significance Index: -8.9500 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.4212
Cell Significance Index: -54.4100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.4807
Cell Significance Index: -56.6900 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.5486
Cell Significance Index: -7.8900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.5552
Cell Significance Index: -63.6100 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.6281
Cell Significance Index: -10.5800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.6789
Cell Significance Index: -16.9700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.7109
Cell Significance Index: -19.3500 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.7391
Cell Significance Index: -9.8600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.7569
Cell Significance Index: -56.4100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.7683
Cell Significance Index: -60.8500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7700
Cell Significance Index: -40.4300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.8114
Cell Significance Index: -52.3500 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.8164
Cell Significance Index: -10.1800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.8216
Cell Significance Index: -50.3700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.8512
Cell Significance Index: -44.3400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.8576
Cell Significance Index: -54.0500 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.9054
Cell Significance Index: -11.6100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.9087
Cell Significance Index: -28.9400 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.9102
Cell Significance Index: -13.0700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.9890
Cell Significance Index: -32.3800 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -1.0428
Cell Significance Index: -20.9400 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -1.0459
Cell Significance Index: -13.2000 - Cell Name: granulosa cell (CL0000501)
Fold Change: -1.0601
Cell Significance Index: -27.8800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -1.0813
Cell Significance Index: -22.9500 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -1.1030
Cell Significance Index: -21.8100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3312416020
Symbol: MYPT2_HUMAN
Name: Protein phosphatase 1 regulatory subunit 12B
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9570949
Title: A new isoform of human myosin phosphatase targeting/regulatory subunit (MYPT2): cDNA cloning, tissue expression, and chromosomal mapping.
PubMed ID: 9570949
PubMed ID: 11067852
Title: Identification, characterization, and functional analysis of heart-specific myosin light chain phosphatase small subunit.
PubMed ID: 11067852
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12923170
Title: PDZ domain-mediated interaction of interleukin-16 precursor proteins with myosin phosphatase targeting subunits.
PubMed ID: 12923170
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 982
- Mass: 110404
- Checksum: A6EBB6AD4C61DD3B
- Sequence:
MAELEHLGGK RAESARMRRA EQLRRWRGSL TEQEPAERRG AGRQPLTRRG SPRVRFEDGA VFLAACSSGD TDEVRKLLAR GADINTVNVD GLTALHQACI DENLDMVKFL VENRANVNQQ DNEGWTPLHA AASCGYLNIA EYFINHGASV GIVNSEGEVP SDLAEEPAMK DLLLEQVKKQ GVDLEQSRKE EEQQMLQDAR QWLNSGKIED VRQARSGATA LHVAAAKGYS EVLRLLIQAG YELNVQDYDG WTPLHAAAHW GVKEACSILA EALCDMDIRN KLGQTPFDVA DEGLVEHLEL LQKKQNVLRS EKETRNKLIE SDLNSKIQSG FFKNKEKMLY EEETPKSQEM EEENKESSSS SSEEEEGEDE ASESETEKEA DKKPEAFVNH SNSESKSSIT EQIPAPAQNT FSASSARRFS SGLFNKPEEP KDESPSSWRL GLRKTGSHNM LSEVANSREP IRDRGSSIYR SSSSPRISAL LDNKDKEREN KSYISSLAPR KLNSTSDIEE KENRESAVNL VRSGSYTRQL WRDEAKGNEI PQTIAPSTYV STYLKRTPHK SQADTTAEKT ADNVSSSTPL CVITNRPLPS TANGVTATPV LSITGTDSSV EAREKRRSYL TPVRDEEAES LRKARSRQAR QTRRSTQGVT LTDLQEAERT FSRSRAERQA QEQPREKPTD TEGLEGSPEK HEPSAVPATE AGEGQQPWGR SLDEEPICHR LRCPAQPDKP TTPASPSTSR PSLYTSSHLL WTNRFSVPDS ESSETTTNTT TAKEMDKNEN EEADLDEQSS KRLSIRERRR PKERRRGTGI NFWTKDEDET DGSEEVKETW HERLSRLESG GSNPTTSDSY GDRASARARR EAREARLATL TSRVEEDSNR DYKKLYESAL TENQKLKTKL QEAQLELADI KSKLEKVAQQ KQEKTSDRSS VLEMEKRERR ALERKMSEME EEMKVLTELK SDNQRLKDEN GALIRVISKL SK
Genular Protein ID: 3175533310
Symbol: E1CKY7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 20801872
Title: Heart-specific small subunit of myosin light chain phosphatase activates rho-associated kinase and regulates phosphorylation of myosin phosphatase target subunit 1.
PubMed ID: 20801872
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 186
- Mass: 21367
- Checksum: C38793FEF36109DE
- Sequence:
MSSLYTRSKE FTRNRKSQSD SPPASPSPTA KTLRHERLSR LESGGSNPTT SDSYGDRASA RARREAREAR LATLTSRVEE DSNRDYKKLY ESALTENQKL KTKLQEAQLE LADIKSKLEK VAQQKQEKTS DRSSVLEMEK RERRALERKM SEMEEEMKVL TELKSDNQRL KDENGALIRV ISKLSK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.