Details for: NAB1

Gene ID: 4664

Symbol: NAB1

Ensembl ID: ENSG00000138386

Description: NGFI-A binding protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 199.2347
    Cell Significance Index: -30.9900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 117.5272
    Cell Significance Index: -29.8100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 66.5376
    Cell Significance Index: -27.4100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 61.4389
    Cell Significance Index: -24.9600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 26.1903
    Cell Significance Index: -25.0100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 25.6214
    Cell Significance Index: -31.5900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 10.7098
    Cell Significance Index: -28.6900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.1427
    Cell Significance Index: -25.0100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.0486
    Cell Significance Index: -31.7600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.8080
    Cell Significance Index: -14.9000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.6406
    Cell Significance Index: 113.4600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.2372
    Cell Significance Index: 16.8800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1409
    Cell Significance Index: 228.8700
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 1.0619
    Cell Significance Index: 8.9200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9636
    Cell Significance Index: 104.8200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.9257
    Cell Significance Index: 25.8700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7088
    Cell Significance Index: 639.9800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6619
    Cell Significance Index: 131.3600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6543
    Cell Significance Index: 234.6800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5659
    Cell Significance Index: 25.6500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.5095
    Cell Significance Index: 26.5400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4368
    Cell Significance Index: 12.5900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3689
    Cell Significance Index: 10.0400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.3473
    Cell Significance Index: 19.4900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3186
    Cell Significance Index: 173.9700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2977
    Cell Significance Index: 18.7600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2643
    Cell Significance Index: 32.5000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2516
    Cell Significance Index: 13.0700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2484
    Cell Significance Index: 47.2700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.2353
    Cell Significance Index: 3.5300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2006
    Cell Significance Index: 138.7500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1990
    Cell Significance Index: 87.9700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1472
    Cell Significance Index: 26.5300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1323
    Cell Significance Index: 60.0500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1252
    Cell Significance Index: 2.1500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1089
    Cell Significance Index: 10.7700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1048
    Cell Significance Index: 2.6200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0942
    Cell Significance Index: 4.3900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0626
    Cell Significance Index: 2.9400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0534
    Cell Significance Index: 82.1400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0411
    Cell Significance Index: 5.6400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.0344
    Cell Significance Index: 0.7300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0295
    Cell Significance Index: 18.7100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0255
    Cell Significance Index: 47.1000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0223
    Cell Significance Index: 42.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0046
    Cell Significance Index: 0.3600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0001
    Cell Significance Index: 0.0200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.0014
    Cell Significance Index: -0.0200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0019
    Cell Significance Index: -0.0400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0159
    Cell Significance Index: -1.0700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0169
    Cell Significance Index: -22.9700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0185
    Cell Significance Index: -1.3800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0298
    Cell Significance Index: -21.8400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0320
    Cell Significance Index: -1.1300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0379
    Cell Significance Index: -28.7100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0420
    Cell Significance Index: -5.3900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0431
    Cell Significance Index: -5.0800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0434
    Cell Significance Index: -2.6700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0444
    Cell Significance Index: -32.9200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0551
    Cell Significance Index: -31.0500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0586
    Cell Significance Index: -36.5800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0808
    Cell Significance Index: -8.2600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0869
    Cell Significance Index: -25.0100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0916
    Cell Significance Index: -10.6800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1134
    Cell Significance Index: -3.2500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1327
    Cell Significance Index: -22.6600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1378
    Cell Significance Index: -8.8900
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.1462
    Cell Significance Index: -2.2200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1463
    Cell Significance Index: -10.3500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1600
    Cell Significance Index: -8.0800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1737
    Cell Significance Index: -36.5800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1999
    Cell Significance Index: -3.3500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2026
    Cell Significance Index: -23.2100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2476
    Cell Significance Index: -7.9300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2883
    Cell Significance Index: -30.0200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3001
    Cell Significance Index: -10.4300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3176
    Cell Significance Index: -6.8800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3273
    Cell Significance Index: -25.9200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3543
    Cell Significance Index: -10.1100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3663
    Cell Significance Index: -7.1500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4010
    Cell Significance Index: -12.7700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4025
    Cell Significance Index: -10.5900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.4096
    Cell Significance Index: -6.9000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4244
    Cell Significance Index: -26.0200
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.4518
    Cell Significance Index: -3.8400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4527
    Cell Significance Index: -23.7700
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.5237
    Cell Significance Index: -6.5300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.5360
    Cell Significance Index: -7.6300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5464
    Cell Significance Index: -17.8900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.5630
    Cell Significance Index: -8.3100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6039
    Cell Significance Index: -26.7100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.6174
    Cell Significance Index: -7.3600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6417
    Cell Significance Index: -22.4800
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.6441
    Cell Significance Index: -9.2500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.6502
    Cell Significance Index: -23.8700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.6530
    Cell Significance Index: -15.6600
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.6719
    Cell Significance Index: -21.2500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6751
    Cell Significance Index: -25.5700
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.7091
    Cell Significance Index: -8.9500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** NAB1 is a multifunctional protein that exhibits characteristics of a transcriptional coregulator. It interacts with NGFI-A, a transcription factor involved in the regulation of various developmental processes. NAB1 has been identified in a range of cell types, including ciliary muscle cells, corticothalamic-projecting glutamatergic cortical neurons, and immature innate lymphoid cells. The protein is also expressed in the nervous system, where it plays a role in the development and differentiation of Schwann cells. **Pathways and Functions:** NAB1 is involved in several signaling pathways, including those mediated by Egr2 and Sox10, which are essential for the initiation of Schwann cell myelination. It also participates in the regulation of endochondral ossification, myelination, and the negative regulation of DNA-templated transcription. NAB1's involvement in the NGF-stimulated transcription pathway highlights its role in the regulation of neuronal development and function. Furthermore, its interaction with receptor tyrosine kinases, such as NTRK1, suggests a role in signal transduction and the regulation of cell growth and differentiation. **Clinical Significance:** NAB1's involvement in immune regulation and development makes it a potential target for the treatment of various diseases. Mutations in the NAB1 gene have been associated with immunodeficiency disorders, such as X-linked lymphoproliferative disease. Additionally, NAB1's role in the regulation of Schwann cell myelination makes it a potential target for the treatment of neurological disorders, such as multiple sclerosis. Further research is needed to fully elucidate the clinical significance of NAB1 and its potential as a therapeutic target. **Conclusion:** In conclusion, NAB1 is a multifunctional protein that plays a critical role in the regulation of immune responses and development. Its involvement in various signaling pathways and transcriptional regulation highlights its importance in the development and function of the nervous system and immune cells. Further research is needed to fully elucidate the clinical significance of NAB1 and its potential as a therapeutic target for the treatment of various diseases. **References:** (No references provided, as this is a summary article written in the style of an expert immunologist) Note: The references section is not provided as it is not necessary for the summary article. However, in a real research paper, you would need to include relevant references to support the information presented in the article.

Genular Protein ID: 921812473

Symbol: NAB1_HUMAN

Name: NGFI-A-binding protein 1

UniProtKB Accession Codes:

Q13506 O75383 O75384 Q6GTU1 Q9UEV1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 9 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 10 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8668170

Title: NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli.

PubMed ID: 8668170

DOI: 10.1128/mcb.16.7.3545

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 21836637

Title: The transcription factor Krox20 is an E3 ligase that sumoylates its Nab coregulators.

PubMed ID: 21836637

DOI: 10.1038/embor.2011.152

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 487
  • Mass: 54401
  • Checksum: 385B16391D670059
  • Sequence:
    • MAAALPRTLG ELQLYRILQK ANLLSYFDAF IQQGGDDVQQ LCEAGEEEFL EIMALVGMAS 
KPLHVRRLQK ALRDWVTNPG LFNQPLTSLP VSSIPIYKLP EGSPTWLGIS CSSYERSSNA 
REPHLKIPKC AATTCVQSLG QGKSDVVGSL ALQSVGESRL WQGHHATESE HSLSPADLGS 
PASPKESSEA LDAAAALSVA ECVERMAPTL PKSDLNEVKE LLKTNKKLAK MIGHIFEMND 
DDPHKEEEIR KYSAIYGRFD SKRKDGKHLT LHELTVNEAA AQLCVKDNAL LTRRDELFAL 
ARQISREVTY KYTYRTTKSK CGERDELSPK RIKVEDGFPD FQDSVQTLFQ QARAKSEELA 
ALSSQQPEKV MAKQMEFLCN QAGYERLQHA ERRLSAGLYR QSSEEHSPNG LTSDNSDGQG 
ERPLNLRMPN LQNRQPHHFV VDGELSRLYP SEAKSHSSES LGILKDYPHS AFTLEKKVIK 
TEPEDSR

Genular Protein ID: 2614286811

Symbol: B4DKG1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DKG1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 4 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1

Sequence Information:

  • Length: 227
  • Mass: 26260
  • Checksum: A32FE3A133F193A3
  • Sequence:
    • MIGHIFEMND DDPHKEEEIR KYSAIYGRFD SKRKDGKHLT LHELTVNEAA AQLCVKDNAL 
LTRRDELFAL ARQISREVTY KYTYRTTKSK CGERDELSPK RIKVEQPEKV MAKQMEFLCN 
QAGYERLQHA ERRLSAGLYR QSSEEHSPNG LTSDNSDGQG ERPLNLRMPN LQNRQPHHFV 
VDGELSRLYP SEAKSHSSES LGILKDYPHS AFTLEKKVIK TEPEDSR

Genular Protein ID: 51859122

Symbol: A8K8T1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K8T1

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 6 RefSeq 1 SAM 1

Sequence Information:

  • Length: 487
  • Mass: 54371
  • Checksum: 385B16391D671C29
  • Sequence:
    • MAAALPRTLG ELQLYRILQK ANLLSYFDAF IQQGGDDVQQ LCEAGEEEFL EIMALVGMAS 
KPLHVRRLQK ALRDWVTNPG LFNQPLTSLP VSSIPIYKLP EGSPTWLGIS CSSYERSSNA 
REPHLKIPKC AATTCVQSLG QGKSDVVGSL ALQSVGESRL WQGHHATESE HSLSPADLGS 
PASPKESSEA LDAAAALSVA ECVERMAPTL PKSDLNEVKE LLKTNKKLAK MIGHIFEMND 
DDPHKEEEIR KYSAIYGRFD SKRKDGKHLT LHELTVNEAA AQLCVKDNAL LTRRDELFAL 
ARQISREVTY KYTYRTTKSK CGERDELSPK RIKVEDGFPD FQDSVQTLFQ QARAKSEELA 
ALSSQQPEKV MAKQMEFLCN QAGYERLQHA ERRLSAGLYR QSSEEHSPNG LTSDNSDGQG 
ERPLNLRMPN LQNRQPHHFV VDGELSRLYP SEAKSHSSES LGILKDYPHS AFTLEKKVIK 
AEPEDSR

Genular Protein ID: 3366312187

Symbol: B8ZZS2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B8ZZS2

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 3 Gene3D 1 GeneTree 1 HGNC 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 6 Proteomes 2 ProteomicsDB 2 RefSeq 6 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.O114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 486
  • Mass: 54273
  • Checksum: BB07867277C8A5EE
  • Sequence:
    • MAAALPRTLG ELQLYRILQK ANLLSYFDAF IQQGGDDVQQ LCEAGEEEFL EIMALVGMAS 
KPLHVRRLQK ALRDWVTNPG LFNQPLTSLP VSSIPIYKLP EGSPTWLGIS CSSYERSSNA 
REPHLKIPKC AATTCVQSLG QGKSDVVGSL ALQSVGESRL WQGHHATESE HSLSPADLGS 
PASPKESSEA LDAAAALSVA ECVERMAPTL PKSDLNEVKE LLKTNKKLAK MIGHIFEMND 
DDPHKEEEIR KYSAIYGRFD SKRKDGKHLT LHELTVNEAA AQLCVKDNAL LTRRDELFAL 
ARQISREVTY KYTYRTTKSK CGERDELSPK RIKVEDGFPD FQDSVQTLFQ QARAKSEELA 
ALSSQPEKVM AKQMEFLCNQ AGYERLQHAE RRLSAGLYRQ SSEEHSPNGL TSDNSDGQGE 
RPLNLRMPNL QNRQPHHFVV DGELSRLYPS EAKSHSSESL GILKDYPHSA FTLEKKVIKT 
EPEDSR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.