Details for: NFIA
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 8.9
Marker Score: 46,708 - Cell Name: stellate neuron (CL0000122)
Fold Change: 5.86
Marker Score: 31,484 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 5.78
Marker Score: 3,802 - Cell Name: granule cell (CL0000120)
Fold Change: 5.6
Marker Score: 42,195 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 5.13
Marker Score: 3,377 - Cell Name: macroglial cell (CL0000126)
Fold Change: 5.06
Marker Score: 11,632 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 4.84
Marker Score: 16,240 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 4.81
Marker Score: 5,449 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 4.38
Marker Score: 3,040 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 4.34
Marker Score: 5,403 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 4.32
Marker Score: 2,421 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 4.31
Marker Score: 2,504 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 4.31
Marker Score: 96,310 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 4.24
Marker Score: 2,356 - Cell Name: contractile cell (CL0000183)
Fold Change: 4.01
Marker Score: 2,175 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 3.95
Marker Score: 3,503 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 3.82
Marker Score: 7,355 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 3.54
Marker Score: 3,380 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 3.54
Marker Score: 1,293 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 3.53
Marker Score: 8,443 - Cell Name: endocardial cell (CL0002350)
Fold Change: 3.46
Marker Score: 1,955 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 3.45
Marker Score: 1,659 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 3.41
Marker Score: 886 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 3.41
Marker Score: 4,126 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 3.4
Marker Score: 3,910 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 3.25
Marker Score: 69,331 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 3.24
Marker Score: 13,578 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 3.21
Marker Score: 1,018 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 3.16
Marker Score: 2,734 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 3.14
Marker Score: 3,358 - Cell Name: hepatoblast (CL0005026)
Fold Change: 3.13
Marker Score: 10,259 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 3.1
Marker Score: 1,533 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 3.08
Marker Score: 7,720 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 3.06
Marker Score: 2,046 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 3.02
Marker Score: 970 - Cell Name: fat cell (CL0000136)
Fold Change: 2.96
Marker Score: 1,656 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.94
Marker Score: 52,114 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 2.91
Marker Score: 10,342 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 2.87
Marker Score: 826 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.8
Marker Score: 6,137 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.74
Marker Score: 7,821 - Cell Name: astrocyte (CL0000127)
Fold Change: 2.71
Marker Score: 2,352 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.68
Marker Score: 784 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.67
Marker Score: 1,560 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.64
Marker Score: 1,540 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 2.58
Marker Score: 3,742 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.55
Marker Score: 2,681 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 2.48
Marker Score: 10,343 - Cell Name: Mueller cell (CL0000636)
Fold Change: 2.46
Marker Score: 3,416 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.46
Marker Score: 83,546 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.45
Marker Score: 1,464 - Cell Name: lactocyte (CL0002325)
Fold Change: 2.38
Marker Score: 38,157 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 2.38
Marker Score: 8,434 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 2.37
Marker Score: 1,178 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 2.37
Marker Score: 31,233 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 2.35
Marker Score: 2,902 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 2.31
Marker Score: 6,038 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 2.29
Marker Score: 1,949 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 2.28
Marker Score: 2,460 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 2.23
Marker Score: 810 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 2.23
Marker Score: 567 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.18
Marker Score: 4,976 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 2.17
Marker Score: 2,323 - Cell Name: basal cell (CL0000646)
Fold Change: 2.17
Marker Score: 2,795 - Cell Name: secretory cell (CL0000151)
Fold Change: 2.12
Marker Score: 3,875 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.09
Marker Score: 31,294 - Cell Name: keratocyte (CL0002363)
Fold Change: 2.07
Marker Score: 476 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 2.06
Marker Score: 646 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 2.05
Marker Score: 2,530 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 2.05
Marker Score: 7,574 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 2.01
Marker Score: 3,294 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.01
Marker Score: 2,215 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.98
Marker Score: 10,665 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.98
Marker Score: 740 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.98
Marker Score: 2,658 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 1.97
Marker Score: 1,037 - Cell Name: fibroblast (CL0000057)
Fold Change: 1.95
Marker Score: 1,888 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 1.93
Marker Score: 558 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 1.93
Marker Score: 1,453 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 1.93
Marker Score: 1,269 - Cell Name: acinar cell (CL0000622)
Fold Change: 1.9
Marker Score: 1,339 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.9
Marker Score: 600 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.88
Marker Score: 5,121 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 1.87
Marker Score: 675 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.87
Marker Score: 70,927 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.86
Marker Score: 634 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.86
Marker Score: 15,976 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.86
Marker Score: 701 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.85
Marker Score: 898 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.84
Marker Score: 17,501 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 1.84
Marker Score: 873 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.84
Marker Score: 1,246 - Cell Name: club cell (CL0000158)
Fold Change: 1.83
Marker Score: 2,140 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.83
Marker Score: 11,739 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 1.83
Marker Score: 11,874 - Cell Name: inflammatory cell (CL0009002)
Fold Change: 1.82
Marker Score: 783 - Cell Name: lymphocyte (CL0000542)
Fold Change: 1.82
Marker Score: 918 - Cell Name: endothelial cell of lymphatic vessel (CL0002138)
Fold Change: 1.82
Marker Score: 1,133 - Cell Name: endothelial cell (CL0000115)
Fold Change: 1.81
Marker Score: 1,621 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 1.8
Marker Score: 1,822
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2830633130
Symbol: NFIA_HUMAN
Name: Nuclear factor 1 A-type
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10718198
Title: Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10718198
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7590749
Title: Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.
PubMed ID: 7590749
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24462883
Title: An intragenic deletion of the NFIA gene in a patient with a hypoplastic corpus callosum, craniofacial abnormalities and urinary tract defects.
PubMed ID: 24462883
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 27081522
Title: Truncating mutation in NFIA causes brain malformation and urinary tract defects.
PubMed ID: 27081522
DOI: 10.1038/hgv.2015.7
PubMed ID: 31375868
Title: The evolution of the 9aaTAD domain in Sp2 proteins: inactivation with valines and intron reservoirs.
PubMed ID: 31375868
Sequence Information:
- Length: 509
- Mass: 55944
- Checksum: 42090C6B8B229F87
- Sequence:
MYSPLCLTQD EFHPFIEALL PHVRAFAYTW FNLQARKRKY FKKHEKRMSK EEERAVKDEL LSEKPEVKQK WASRLLAKLR KDIRPEYRED FVLTVTGKKP PCCVLSNPDQ KGKMRRIDCL RQADKVWRLD LVMVILFKGI PLESTDGERL VKSPQCSNPG LCVQPHHIGV SVKELDLYLA YFVHAADSSQ SESPSQPSDA DIKDQPENGH LGFQDSFVTS GVFSVTELVR VSQTPIAAGT GPNFSLSDLE SSSYYSMSPG AMRRSLPSTS STSSTKRLKS VEDEMDSPGE EPFYTGQGRS PGSGSQSSGW HEVEPGMPSP TTLKKSEKSG FSSPSPSQTS SLGTAFTQHH RPVITGPRAS PHATPSTLHF PTSPIIQQPG PYFSHPAIRY HPQETLKEFV QLVCPDAGQQ AGQVGFLNPN GSSQGKVHNP FLPTPMLPPP PPPPMARPVP LPVPDTKPPT TSTEGGAASP TSPTYSTPST SPANRFVSVG PRDPSFVNIP QQTQSWYLG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.