Details for: NFIB
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 1045.9016
Cell Significance Index: -162.6900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 642.9894
Cell Significance Index: -163.0900 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 416.3515
Cell Significance Index: -171.5200 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 328.5375
Cell Significance Index: -155.1100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 319.9575
Cell Significance Index: -129.9900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 136.6232
Cell Significance Index: -130.4400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 131.9958
Cell Significance Index: -162.7500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 44.7092
Cell Significance Index: -97.8500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 41.2108
Cell Significance Index: -162.6200 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 40.7218
Cell Significance Index: -125.0800 - Cell Name: preadipocyte (CL0002334)
Fold Change: 7.2019
Cell Significance Index: 140.5600 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 6.5520
Cell Significance Index: 99.5100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 5.0785
Cell Significance Index: 1821.5600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 4.8442
Cell Significance Index: 297.7500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 3.8409
Cell Significance Index: 294.7500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 3.6176
Cell Significance Index: 1599.4200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 3.6002
Cell Significance Index: 51.7800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 3.3919
Cell Significance Index: 176.6800 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 3.1994
Cell Significance Index: 28.4000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 3.0568
Cell Significance Index: 356.2400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.5789
Cell Significance Index: 121.2100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 2.4538
Cell Significance Index: 173.5400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 2.3259
Cell Significance Index: 55.7800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.1090
Cell Significance Index: 58.9400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.0867
Cell Significance Index: 97.2900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.9607
Cell Significance Index: 1770.3400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.8854
Cell Significance Index: 378.2000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.8130
Cell Significance Index: 121.9100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 1.5709
Cell Significance Index: 26.9200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.4434
Cell Significance Index: 998.3000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.0039
Cell Significance Index: 1890.2700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.8775
Cell Significance Index: 21.9400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.8136
Cell Significance Index: 13.7100 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.7902
Cell Significance Index: 102.0900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.7395
Cell Significance Index: 80.4400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.6017
Cell Significance Index: 328.6200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.4883
Cell Significance Index: 88.0200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4279
Cell Significance Index: 9.2700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.4068
Cell Significance Index: 626.2200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.4043
Cell Significance Index: 745.5900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.3873
Cell Significance Index: 526.6200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.3452
Cell Significance Index: 219.2200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3054
Cell Significance Index: 37.5600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1999
Cell Significance Index: 11.2200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.1500
Cell Significance Index: 3.1400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0148
Cell Significance Index: 0.5200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0363
Cell Significance Index: -6.2000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0517
Cell Significance Index: -5.1100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.0524
Cell Significance Index: -9.9700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0704
Cell Significance Index: -10.2300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0809
Cell Significance Index: -50.5100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0851
Cell Significance Index: -38.6100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.1375
Cell Significance Index: -100.7900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.1439
Cell Significance Index: -106.6200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.1647
Cell Significance Index: -4.7400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.1855
Cell Significance Index: -140.3900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.2088
Cell Significance Index: -28.6800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.2819
Cell Significance Index: -158.9900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.4015
Cell Significance Index: -18.2000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.5454
Cell Significance Index: -156.9300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.6589
Cell Significance Index: -130.7700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.6899
Cell Significance Index: -70.4700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.7759
Cell Significance Index: -88.9000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.7868
Cell Significance Index: -165.7300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.8000
Cell Significance Index: -22.8300 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.9164
Cell Significance Index: -13.1600 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.9384
Cell Significance Index: -120.3000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.9980
Cell Significance Index: -6.0300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -1.0490
Cell Significance Index: -72.5500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.0551
Cell Significance Index: -27.1200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -1.0827
Cell Significance Index: -80.6900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -1.2315
Cell Significance Index: -140.5700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -1.2506
Cell Significance Index: -34.0400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -1.2830
Cell Significance Index: -133.5900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.3346
Cell Significance Index: -81.8300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -1.3359
Cell Significance Index: -157.5400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.3922
Cell Significance Index: -23.3000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -1.4488
Cell Significance Index: -21.3900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -1.4914
Cell Significance Index: -78.3100 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -1.5396
Cell Significance Index: -22.7300 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -1.6584
Cell Significance Index: -23.1900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.7643
Cell Significance Index: -139.7300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -1.8776
Cell Significance Index: -40.1400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -2.2165
Cell Significance Index: -70.9900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -2.2985
Cell Significance Index: -119.4000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -2.4357
Cell Significance Index: -157.1400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -2.5534
Cell Significance Index: -83.6000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -2.6513
Cell Significance Index: -84.4400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -2.7133
Cell Significance Index: -171.0100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -2.9673
Cell Significance Index: -85.0600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -3.5007
Cell Significance Index: -92.0500 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -3.5637
Cell Significance Index: -62.9800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -3.5712
Cell Significance Index: -125.1100 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: -3.6326
Cell Significance Index: -26.4100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -3.7167
Cell Significance Index: -164.4000 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -3.9041
Cell Significance Index: -78.3800 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -3.9713
Cell Significance Index: -68.6700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -3.9812
Cell Significance Index: -106.3100 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -4.0006
Cell Significance Index: -146.8600 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -4.1231
Cell Significance Index: -89.0800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1487668026
Symbol: NFIB_HUMAN
Name: Nuclear factor 1 B-type
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9484777
Title: Identification of NFIB as recurrent translocation partner gene of HMGIC in pleomorphic adenomas.
PubMed ID: 9484777
PubMed ID: 9099724
Title: NFI-B3, a novel transcriptional repressor of the nuclear factor I family, is generated by alternative RNA processing.
PubMed ID: 9099724
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7590749
Title: Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.
PubMed ID: 7590749
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 31375868
Title: The evolution of the 9aaTAD domain in Sp2 proteins: inactivation with valines and intron reservoirs.
PubMed ID: 31375868
PubMed ID: 30388402
Title: NFIB haploinsufficiency is associated with intellectual disability and macrocephaly.
PubMed ID: 30388402
Sequence Information:
- Length: 420
- Mass: 47442
- Checksum: 0F71635FE9D64FA4
- Sequence:
MMYSPICLTQ DEFHPFIEAL LPHVRAIAYT WFNLQARKRK YFKKHEKRMS KDEERAVKDE LLSEKPEIKQ KWASRLLAKL RKDIRQEYRE DFVLTVTGKK HPCCVLSNPD QKGKIRRIDC LRQADKVWRL DLVMVILFKG IPLESTDGER LMKSPHCTNP ALCVQPHHIT VSVKELDLFL AYYVQEQDSG QSGSPSHNDP AKNPPGYLED SFVKSGVFNV SELVRVSRTP ITQGTGVNFP IGEIPSQPYY HDMNSGVNLQ RSLSSPPSSK RPKTISIDEN MEPSPTGDFY PSPSSPAAGS RTWHERDQDM SSPTTMKKPE KPLFSSASPQ DSSPRLSTFP QHHHPGIPGV AHSVISTRTP PPPSPLPFPT QAILPPAPSS YFSHPTIRYP PHLNPQDTLK NYVPSYDPSS PQTSQSWYLG
Genular Protein ID: 2727326291
Symbol: A0A0A0MRX8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 446
- Mass: 50290
- Checksum: 1EFD52F36D29368D
- Sequence:
MERIPVSVDF WVVCCAVLKC NPGIPKRMST LCFGFSDEFH PFIEALLPHV RAIAYTWFNL QARKRKYFKK HEKRMSKDEE RAVKDELLSE KPEIKQKWAS RLLAKLRKDI RQEYREDFVL TVTGKKHPCC VLSNPDQKGK IRRIDCLRQA DKVWRLDLVM VILFKGIPLE STDGERLMKS PHCTNPALCV QPHHITVSVK ELDLFLAYYV QEQDSGQSGS PSHNDPAKNP PGYLEDSFVK SGVFNVSELV RVSRTPITQG TGVNFPIGEI PSQPYYHDMN SGVNLQRSLS SPPSSKRPKT ISIDENMEPS PTGDFYPSPS SPAAGSRTWH ERDQDMSSPT TMKKPEKPLF SSASPQDSSP RLSTFPQHHH PGIPGVAHSV ISTRTPPPPS PLPFPTQAIL PPAPSSYFSH PTIRYPPHLN PQDTLKNYVP SYDPSSPQTS QSWYLG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.