Details for: NOS1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 37.9667
Cell Significance Index: -9.6300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 3.0391
Cell Significance Index: 78.1200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 2.7872
Cell Significance Index: 61.0300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.3942
Cell Significance Index: -5.2400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.4462
Cell Significance Index: 63.9700 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 1.4025
Cell Significance Index: 34.2200 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 1.0791
Cell Significance Index: 26.9100 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 1.0415
Cell Significance Index: 16.8100 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 0.6611
Cell Significance Index: 10.0400 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 0.4603
Cell Significance Index: 5.9700 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.4493
Cell Significance Index: 310.7800 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 0.3346
Cell Significance Index: 2.9700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.2644
Cell Significance Index: 6.3400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2535
Cell Significance Index: 15.5800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.2328
Cell Significance Index: 3.9900 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.2125
Cell Significance Index: 1.4400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.2123
Cell Significance Index: 8.0400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.2022
Cell Significance Index: 5.7700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1693
Cell Significance Index: 4.7300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1673
Cell Significance Index: 33.5600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1150
Cell Significance Index: 50.8600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1117
Cell Significance Index: 40.0500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0884
Cell Significance Index: 6.2500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0566
Cell Significance Index: 106.4800 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.0564
Cell Significance Index: 0.7700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0496
Cell Significance Index: 1.3500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0440
Cell Significance Index: 8.7400 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 0.0440
Cell Significance Index: 0.6100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0254
Cell Significance Index: 1.7100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0165
Cell Significance Index: 2.1100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0157
Cell Significance Index: 8.5900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0155
Cell Significance Index: 11.3700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0148
Cell Significance Index: 20.1700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0021
Cell Significance Index: 3.8200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0014
Cell Significance Index: 2.2100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0005
Cell Significance Index: 0.0800 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0015
Cell Significance Index: -0.0300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0017
Cell Significance Index: -0.2500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0024
Cell Significance Index: -1.5500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0092
Cell Significance Index: -4.1700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0134
Cell Significance Index: -9.9100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0144
Cell Significance Index: -10.8900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0177
Cell Significance Index: -11.0600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0179
Cell Significance Index: -10.0700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0181
Cell Significance Index: -3.2700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0255
Cell Significance Index: -7.3500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0265
Cell Significance Index: -0.3800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0316
Cell Significance Index: -0.6700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0398
Cell Significance Index: -3.0600 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0403
Cell Significance Index: -0.8700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0491
Cell Significance Index: -6.0400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0510
Cell Significance Index: -10.7500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0680
Cell Significance Index: -9.3500 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.0818
Cell Significance Index: -1.0200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0819
Cell Significance Index: -9.3800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0839
Cell Significance Index: -8.5800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0840
Cell Significance Index: -8.7500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0846
Cell Significance Index: -6.7000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0903
Cell Significance Index: -10.5200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1062
Cell Significance Index: -4.9500 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.1131
Cell Significance Index: -2.7400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1251
Cell Significance Index: -7.8900 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.1276
Cell Significance Index: -5.5500 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.1529
Cell Significance Index: -1.9300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1566
Cell Significance Index: -8.7900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1621
Cell Significance Index: -8.4500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1640
Cell Significance Index: -7.7100 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.1714
Cell Significance Index: -2.0500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1722
Cell Significance Index: -10.5600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1790
Cell Significance Index: -9.3000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1792
Cell Significance Index: -9.4100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1874
Cell Significance Index: -8.5000 - Cell Name: neural cell (CL0002319)
Fold Change: -0.2109
Cell Significance Index: -2.4600 - Cell Name: neuron (CL0000540)
Fold Change: -0.2163
Cell Significance Index: -2.0500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2220
Cell Significance Index: -7.0700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2269
Cell Significance Index: -7.9500 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: -0.2271
Cell Significance Index: -3.1400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2346
Cell Significance Index: -7.6800 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.2361
Cell Significance Index: -4.7400 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: -0.2397
Cell Significance Index: -2.1600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.2443
Cell Significance Index: -8.4900 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2467
Cell Significance Index: -4.8200 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.2526
Cell Significance Index: -3.5400 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: -0.2774
Cell Significance Index: -3.6200 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.2784
Cell Significance Index: -10.2200 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.2827
Cell Significance Index: -8.9400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.2835
Cell Significance Index: -8.3500 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.2852
Cell Significance Index: -4.0600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.3000
Cell Significance Index: -10.5400 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.3112
Cell Significance Index: -3.9900 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.3137
Cell Significance Index: -4.2300 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.3199
Cell Significance Index: -7.9800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.3213
Cell Significance Index: -8.5800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.3292
Cell Significance Index: -8.8200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3335
Cell Significance Index: -9.5600 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.3342
Cell Significance Index: -5.0000 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.3345
Cell Significance Index: -8.3600 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.3397
Cell Significance Index: -5.0200 - Cell Name: interneuron (CL0000099)
Fold Change: -0.3459
Cell Significance Index: -4.0400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.3509
Cell Significance Index: -10.1100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3182580408
Symbol: NOS1_HUMAN
Name: Constitutive NOS
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7528745
Title: Structural organization of the human neuronal nitric oxide synthase gene (NOS1).
PubMed ID: 7528745
PubMed ID: 7515942
Title: Expression of two types of nitric oxide synthase mRNA in human neuroblastoma cell lines.
PubMed ID: 7515942
PubMed ID: 7678401
Title: Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle.
PubMed ID: 7678401
PubMed ID: 8879752
Title: Neuronal isoform of nitric oxide synthase is expressed at low levels in human retina.
PubMed ID: 8879752
DOI: 10.1007/bf02150230
PubMed ID: 9111048
Title: A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase.
PubMed ID: 9111048
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 9791007
Title: Isolation and characterization of a novel, human neuronal nitric oxide synthase cDNA.
PubMed ID: 9791007
PubMed ID: 35772285
Title: 2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
PubMed ID: 35772285
PubMed ID: 25286850
Title: Structures of human constitutive nitric oxide synthases.
PubMed ID: 25286850
Sequence Information:
- Length: 1434
- Mass: 160970
- Checksum: 99235793B953BF37
- Sequence:
MEDHMFGVQQ IQPNVISVRL FKRKVGGLGF LVKERVSKPP VIISDLIRGG AAEQSGLIQA GDIILAVNGR PLVDLSYDSA LEVLRGIASE THVVLILRGP EGFTTHLETT FTGDGTPKTI RVTQPLGPPT KAVDLSHQPP AGKEQPLAVD GASGPGNGPQ HAYDDGQEAG SLPHANGLAP RPPGQDPAKK ATRVSLQGRG ENNELLKEIE PVLSLLTSGS RGVKGGAPAK AEMKDMGIQV DRDLDGKSHK PLPLGVENDR VFNDLWGKGN VPVVLNNPYS EKEQPPTSGK QSPTKNGSPS KCPRFLKVKN WETEVVLTDT LHLKSTLETG CTEYICMGSI MHPSQHARRP EDVRTKGQLF PLAKEFIDQY YSSIKRFGSK AHMERLEEVN KEIDTTSTYQ LKDTELIYGA KHAWRNASRC VGRIQWSKLQ VFDARDCTTA HGMFNYICNH VKYATNKGNL RSAITIFPQR TDGKHDFRVW NSQLIRYAGY KQPDGSTLGD PANVQFTEIC IQQGWKPPRG RFDVLPLLLQ ANGNDPELFQ IPPELVLEVP IRHPKFEWFK DLGLKWYGLP AVSNMLLEIG GLEFSACPFS GWYMGTEIGV RDYCDNSRYN ILEEVAKKMN LDMRKTSSLW KDQALVEINI AVLYSFQSDK VTIVDHHSAT ESFIKHMENE YRCRGGCPAD WVWIVPPMSG SITPVFHQEM LNYRLTPSFE YQPDPWNTHV WKGTNGTPTK RRAIGFKKLA EAVKFSAKLM GQAMAKRVKA TILYATETGK SQAYAKTLCE IFKHAFDAKV MSMEEYDIVH LEHETLVLVV TSTFGNGDPP ENGEKFGCAL MEMRHPNSVQ EERKSYKVRF NSVSSYSDSQ KSSGDGPDLR DNFESAGPLA NVRFSVFGLG SRAYPHFCAF GHAVDTLLEE LGGERILKMR EGDELCGQEE AFRTWAKKVF KAACDVFCVG DDVNIEKANN SLISNDRSWK RNKFRLTFVA EAPELTQGLS NVHKKRVSAA RLLSRQNLQS PKSSRSTIFV RLHTNGSQEL QYQPGDHLGV FPGNHEDLVN ALIERLEDAP PVNQMVKVEL LEERNTALGV ISNWTDELRL PPCTIFQAFK YYLDITTPPT PLQLQQFASL ATSEKEKQRL LVLSKGLQEY EEWKWGKNPT IVEVLEEFPS IQMPATLLLT QLSLLQPRYY SISSSPDMYP DEVHLTVAIV SYRTRDGEGP IHHGVCSSWL NRIQADELVP CFVRGAPSFH LPRNPQVPCI LVGPGTGIAP FRSFWQQRQF DIQHKGMNPC PMVLVFGCRQ SKIDHIYREE TLQAKNKGVF RELYTAYSRE PDKPKKYVQD ILQEQLAESV YRALKEQGGH IYVCGDVTMA ADVLKAIQRI MTQQGKLSAE DAGVFISRMR DDNRYHEDIF GVTLRTYEVT NRLRSESIAF IEESKKDTDE VFSS
Genular Protein ID: 3063550731
Symbol: B4DG68_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1206
- Mass: 134816
- Checksum: E4DBC7937045D909
- Sequence:
MEDHMFGVQQ IQPNVISVRL FKRKVGGLGF LVKERVSKPP VIISDLIRGG AAEQSGLIQA GDIILAVNGR PLVDLSYDSA LEVLRGIASE THVVLILRGP EGFTTHLETT FTGDGTPKTI RVTQPLGPPT KAVDLSHQPP AGKEQPLAVD GASGPGNGPQ HAYDDGQEAG SLPHANGLAP RPPGQDPAKK ATRVSLQGRG ENNELLKEIE PVLSLLTSGS RGVKGGAPAK AEMKDMGIQV DRDLDGKSHK PLPLGVENDR VFNDLWGKGN VPVVLNNPYS EKEQPPTSGK QSPTKNGSPS KCPRFLKVKN WETEVVLTDT LHLKSTLETG CTEYICMGSI MHPSQHARRP EDVRTKGQLF PLAKEFIDQY YSSIKRFGSK AHMERLEEVN KEIDTTSTYQ LKDTELIYGA KHAWRNASRC VGRIQWSKLQ VFDARDCTTA HGMFNYICNH VKYATNKGNL RSAITIFPQR TDGKHDFRVW NSQLIRYAGY KQPDGSTLGD PANVQFTEIC IQQGWKPPRG RFDVLPLLLQ ANVNDPELFQ IPPELVLEVP IRHPKFEWFK DLGLKWYGLP AVSNMLLEIG GLEFSACPFS GWYMGTEIGV RDYCDNSRYN ILEEVAKKLN LDMRKTSSLW KDQALVEINI AVLYSFQSDK VTIVDHHSAT ESFIKHMENE YRCRGGCPAD WVWIVPPMSG SITPVFHQEM LNYRLTPSFE YQPDPWNTHV WKGTNGTPTK RRAIGFKKLA EAVKFSAKLM GQAMAKRVKA TILYATETGK SQAYAKTLCE IFKHAFDAKV MSMEEYDIVH LEHETLVLVV TSTFGNGDPP ENGEKFGCAL MEMRHPNSVQ EERKSYKVRF NSVSSYSDSQ KSSGDGPDLR DNFESAGPLA NVRFSVFGLG SRAYPHFCAF GHAVDTLLEE LGGERILKMR EGDELCGQEE AFRTWAKKVF KAACDVFCVG DDVNIEKANN SLISNDRSWK RNKFRLTFVA EAPELTQGLS NVHKKRVSAA RLLSRQNLQS PKSSRSTIFV RLHTNGSQEL QYQPGDHLGV FPGNHEDLVN ALIERLEDAP PVNQMVKVEL LEERNTALGV ISNWTDELRL PPCTIFQAFK YYLDITTPPT PLQLQQFASL ATSEKEKQRL LVLSKGLQEY EEWKWGKNPT IVEVLEEFPS IQMPATLLLT QLSLLQPRYY SISSSPHTHT LSETRPSPLP LSSQCC
Genular Protein ID: 2705104398
Symbol: A0PJJ7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 92
- Mass: 10404
- Checksum: 0351AFCEF91E43C2
- Sequence:
ALKEQGGHIY VCGDVTMAAD VLKAIQRIMT QQGKLSAEDA GVFISRMRDD NRYHEDIFGV TLRTYEVTNR LRSESIAFIE ESKKDTDEVF SS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.