Details for: GOLM1
Gene ID: 51280
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: GOLM1
Ensembl ID: ENSG00000135052
Description: golgi membrane protein 1
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 50.07rCSI 60.95%PRS 86.93
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CSI 44.98rCSI 48.2%PRS 82.32
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CSI 40.45rCSI 42.37%PRS 78.34
-
CSI 39.39rCSI 62.57%PRS 89
-
CSI 35.38rCSI 51%PRS 87.34
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CSI 33.08rCSI 35.14%PRS 85.82
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CSI 32.82rCSI 40.82%PRS 81.67
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CSI 30.87rCSI 32.27%PRS 78.43
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CSI 20.47rCSI 24.04%PRS 82.51
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CSI 20.23rCSI 23.47%PRS 84.54
-
CSI 18.99rCSI 40.43%PRS 86.56
-
CSI 18.89rCSI 18.21%PRS 74.43
-
CSI 16.54rCSI 36.1%PRS 87.62
-
CSI 15.32rCSI 20.36%PRS 86.18
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CSI 15rCSI 22.14%PRS 90.34
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CSI 14.72rCSI 11.96%PRS 80.22
-
CSI 14.43rCSI 28.07%PRS 83.81
-
CSI 13.95rCSI 22.49%PRS 79.99
-
CSI 13.67rCSI 36.85%PRS 85.29
-
CSI 12.99rCSI 13.55%PRS 80.32
-
CSI 11.08rCSI 16.95%PRS 88.66
-
CSI 10.48rCSI 55.05%PRS 85.74
-
CSI 9.53rCSI 16.33%PRS 86.49
-
CSI 8.67rCSI 11.85%PRS 80.52
-
CSI 8.23rCSI 16.51%PRS 71.38
-
CSI 8.07rCSI 11.81%PRS 85.59
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CSI 7.76rCSI 9.96%PRS 76.94
-
CSI 7.67rCSI 12.24%PRS 72.51
-
CSI 7.55rCSI 7.13%PRS 79.42
-
CSI 7.5rCSI 10.03%PRS 86.74
-
CSI 7.44rCSI 8.6%PRS 73.03
-
CSI 7.38rCSI 5.84%PRS 70.05
-
CSI 7.36rCSI 8.79%PRS 63.35
-
CSI 7.29rCSI 16.63%PRS 72.61
-
CSI 7.22rCSI 29.43%PRS 88.99
-
CSI 7.12rCSI 25.62%PRS 61.19
-
CSI 7.12rCSI 9.89%PRS 79.4
-
CSI 6.98rCSI 15.65%PRS 64.05
-
CSI 6.91rCSI 27.63%PRS 88.48
-
CSI 6.83rCSI 6.82%PRS 74.85
-
CSI 6.7rCSI 7.01%PRS 84.04
-
CSI 6.51rCSI 11.83%PRS 72.58
-
CSI 6.5rCSI 6.26%PRS 80.17
-
CSI 6.48rCSI 9.95%PRS 70.3
-
CSI 6.42rCSI 12.02%PRS 69.49
-
CSI 6.38rCSI 16.19%PRS 74.39
-
CSI 6.33rCSI 4.91%PRS 84.58
-
CSI 6.28rCSI 12.74%PRS 59.75
-
CSI 6.23rCSI 15.13%PRS 61.24
-
CSI 6.11rCSI 12.68%PRS 77.61
-
CSI 6.09rCSI 26.74%PRS 88.12
-
CSI 6.08rCSI 7.56%PRS 61.14
-
CSI 5.9rCSI 8.42%PRS 81.68
-
CSI 5.88rCSI 18.87%PRS 82.61
-
CSI 5.82rCSI 43.7%PRS 89.75
-
CSI 5.82rCSI 4.82%PRS 81.68
-
CSI 5.8rCSI 13.38%PRS 69.06
-
CSI 5.77rCSI 8.82%PRS 81.04
-
CSI 5.7rCSI 12.55%PRS 87.93
-
CSI 5.68rCSI 8.31%PRS 75.52
-
CSI 5.63rCSI 4.95%PRS 70.31
-
CSI 5.31rCSI 13.15%PRS 80.87
-
CSI 5.03rCSI 8.7%PRS 72.71
-
CSI 4.9rCSI 13.74%PRS 87.35
-
CSI 4.85rCSI 52.81%PRS 88.5
-
CSI 4.8rCSI 22.49%PRS 88.45
-
CSI 4.61rCSI 4.1%PRS 78.64
-
CSI 4.56rCSI 10.87%PRS 81.02
-
CSI 4.55rCSI 5.26%PRS 73.39
-
CSI 4.51rCSI 6.62%PRS 89.61
-
CSI 4.4rCSI 3.8%PRS 81.76
-
CSI 4.37rCSI 7.07%PRS 75.83
-
CSI 4.35rCSI 10.33%PRS 81.03
-
CSI 4.27rCSI 41.92%PRS 88.91
-
CSI 4.24rCSI 7.11%PRS 63.19
-
CSI 4.23rCSI 5.08%PRS 78.85
-
CSI 4.21rCSI 7.39%PRS 75.15
-
CSI 4.15rCSI 8.82%PRS 75.04
-
CSI 4rCSI 6.43%PRS 64.76
-
CSI 3.97rCSI 6.34%PRS 84.47
-
CSI 3.86rCSI 4.92%PRS 85.79
-
CSI 3.81rCSI 6.25%PRS 70.59
-
CSI 3.81rCSI 9.85%PRS 76.43
-
CSI 3.77rCSI 11.14%PRS 81.71
-
CSI 3.76rCSI 11.16%PRS 88.97
-
CSI 3.59rCSI 11.22%PRS 64.91
-
CSI 3.49rCSI 8.36%PRS 84.42
-
CSI 3.46rCSI 5.5%PRS 74.12
-
CSI 3.39rCSI 11.48%PRS 78.38
-
CSI 3.3rCSI 4.89%PRS 84.7
-
CSI 3.27rCSI 4.22%PRS 64.42
-
CSI 3.26rCSI 6.11%PRS 87.46
-
CSI 3.24rCSI 6.43%PRS 76.56
-
CSI 3.22rCSI 5.85%PRS 90.27
-
CSI 3.22rCSI 12.05%PRS 73.66
-
CSI 3.19rCSI 4.7%PRS 74.02
-
CSI 3.17rCSI 5.62%PRS 50.17
-
CSI 3.13rCSI 11.92%PRS 72.15
-
CSI 3.11rCSI 12.68%PRS 73.02
-
CSI 3.1rCSI 4.24%PRS 72.45
-
CSI 0.2rCSI 4.8%PRS 94.1%
-
CSI 0.3rCSI 7.7%PRS 90.4%
-
CSI 0.3rCSI 8.2%PRS 61.5%
-
CSI 0.4rCSI 9.1%PRS 91.7%
-
CSI 0.4rCSI 9.5%PRS 62.1%
-
CSI 0.4rCSI 6.8%PRS 82.1%
-
CSI 0.5rCSI 2.9%PRS 88.1%
-
CSI 0.7rCSI 0.9%PRS 48.0%
-
CSI 0.7rCSI 3.6%PRS 75.7%
-
CSI 0.7rCSI 8.3%PRS 89.8%
-
CSI 0.8rCSI 5.1%PRS 76.8%
-
CSI 0.8rCSI 2.8%PRS 84.7%
-
CSI 0.9rCSI 8.3%PRS 95.6%
-
CSI 0.9rCSI 2.9%PRS 66.9%
-
CSI 1.0rCSI 5.3%PRS 88.1%
-
CSI 1.0rCSI 7.3%PRS 68.5%
-
CSI 1.0rCSI 1.2%PRS 61.9%
-
CSI 1.1rCSI 6.7%PRS 95.7%
-
CSI 1.2rCSI 10.0%PRS 69.3%
-
CSI 1.2rCSI 3.5%PRS 70.6%
-
CSI 1.2rCSI 2.3%PRS 93.4%
-
CSI 1.2rCSI 2.7%PRS 66.9%
-
CSI 1.3rCSI 1.3%PRS 84.7%
-
CSI 1.3rCSI 4.4%PRS 88.4%
-
CSI 1.3rCSI 6.4%PRS 77.3%
-
CSI 1.4rCSI 3.5%PRS 75.5%
-
CSI 1.4rCSI 5.4%PRS 88.9%
-
CSI 1.4rCSI 8.1%PRS 77.5%
-
CSI 1.5rCSI 3.8%PRS 71.6%
-
CSI 1.7rCSI 3.7%PRS 80.3%
-
CSI 1.7rCSI 15.4%PRS 81.8%
-
CSI 1.7rCSI 2.7%PRS 84.4%
-
CSI 1.7rCSI 1.8%PRS 87.8%
-
CSI 1.8rCSI 5.5%PRS 67.3%
-
CSI 1.8rCSI 2.5%PRS 77.7%
-
CSI 1.8rCSI 4.5%PRS 85.7%
-
CSI 1.8rCSI 7.0%PRS 87.6%
-
CSI 1.8rCSI 4.7%PRS 91.6%
-
CSI 1.8rCSI 3.2%PRS 62.6%
-
CSI 1.9rCSI 2.9%PRS 77.8%
-
CSI 2.0rCSI 3.1%PRS 80.1%
-
CSI 2.0rCSI 21.6%PRS 77.1%
-
CSI 2.1rCSI 7.8%PRS 63.8%
-
CSI 2.1rCSI 7.0%PRS 65.0%
-
CSI 2.2rCSI 3.8%PRS 88.9%
-
CSI 2.2rCSI 13.0%PRS 82.8%
-
CSI 2.2rCSI 3.0%PRS 82.6%
-
CSI 2.2rCSI 3.1%PRS 81.3%
-
CSI 2.2rCSI 5.2%PRS 85.9%
-
CSI 2.3rCSI 2.2%PRS 83.4%
-
CSI 2.3rCSI 5.9%PRS 87.6%
-
CSI 2.3rCSI 35.7%PRS 88.2%
-
CSI 2.3rCSI 5.3%PRS 74.5%
-
CSI 2.3rCSI 10.1%PRS 87.6%
-
CSI 2.5rCSI 11.0%PRS 69.4%
-
CSI 2.5rCSI 3.5%PRS 72.7%
-
CSI 2.6rCSI 4.7%PRS 80.2%
-
CSI 2.7rCSI 13.8%PRS 94.2%
-
CSI 2.7rCSI 3.5%PRS 84.0%
-
CSI 2.7rCSI 2.5%PRS 81.7%
-
CSI 2.8rCSI 5.7%PRS 68.3%
-
CSI 2.8rCSI 16.3%PRS 63.9%
-
CSI 2.9rCSI 11.0%PRS 63.8%
-
CSI 3.0rCSI 7.2%PRS 67.9%
-
CSI 3.1rCSI 4.2%PRS 72.5%
-
CSI 3.1rCSI 12.7%PRS 73.0%
-
CSI 3.1rCSI 11.9%PRS 72.2%
-
CSI 3.2rCSI 5.6%PRS 50.2%
-
CSI 3.2rCSI 4.7%PRS 74.0%
-
CSI 3.2rCSI 12.1%PRS 73.7%
-
CSI 3.2rCSI 5.9%PRS 90.3%
-
CSI 3.2rCSI 6.4%PRS 76.6%
-
CSI 3.3rCSI 6.1%PRS 87.5%
-
CSI 3.3rCSI 4.2%PRS 64.4%
-
CSI 3.3rCSI 4.9%PRS 84.7%
-
CSI 3.4rCSI 11.5%PRS 78.4%
-
CSI 3.5rCSI 5.5%PRS 74.1%
-
CSI 3.5rCSI 8.4%PRS 84.4%
-
CSI 3.6rCSI 11.2%PRS 64.9%
-
CSI 3.8rCSI 11.2%PRS 89.0%
-
CSI 3.8rCSI 11.1%PRS 81.7%
-
CSI 3.8rCSI 9.9%PRS 76.4%
-
CSI 3.8rCSI 6.3%PRS 70.6%
-
CSI 3.9rCSI 4.9%PRS 85.8%
-
CSI 4.0rCSI 6.3%PRS 84.5%
-
CSI 4.0rCSI 6.4%PRS 64.8%
-
CSI 4.2rCSI 8.8%PRS 75.0%
-
CSI 4.2rCSI 7.4%PRS 75.2%
-
CSI 4.2rCSI 5.1%PRS 78.9%
-
CSI 4.2rCSI 7.1%PRS 63.2%
-
CSI 4.3rCSI 41.9%PRS 88.9%
-
CSI 4.4rCSI 10.3%PRS 81.0%
-
CSI 4.4rCSI 7.1%PRS 75.8%
-
CSI 4.4rCSI 3.8%PRS 81.8%
-
CSI 4.5rCSI 6.6%PRS 89.6%
-
CSI 4.6rCSI 5.3%PRS 73.4%
-
CSI 4.6rCSI 10.9%PRS 81.0%
-
CSI 4.6rCSI 4.1%PRS 78.6%
-
CSI 4.8rCSI 22.5%PRS 88.5%
-
CSI 4.9rCSI 52.8%PRS 88.5%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 1112091813
Symbol: GOLM1_HUMAN
Name: Golgi membrane protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10831838
Title: GP73, a novel Golgi-localized protein upregulated by viral infection.
PubMed ID: 10831838
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 16303743
Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.
PubMed ID: 16303743
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12191016
Title: Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption.
PubMed ID: 12191016
PubMed ID: 12029628
Title: Expression of GP73, a resident Golgi membrane protein, in viral and nonviral liver disease.
PubMed ID: 12029628
PubMed ID: 12359426
Title: Upregulation of the Golgi protein GP73 by adenovirus infection requires the E1A CtBP interaction domain.
PubMed ID: 12359426
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 16740002
Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.
PubMed ID: 16740002
DOI: 10.1021/pr050492k
PubMed ID: 19139490
Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.
PubMed ID: 19139490
PubMed ID: 21280149
Title: Dymeclin, the gene underlying Dyggve-Melchior-Clausen syndrome, encodes a protein integral to extracellular matrix and Golgi organization and is associated with protein secretion pathways critical in bone development.
PubMed ID: 21280149
DOI: 10.1002/humu.21413
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 25732826
Title: An organellar nalpha-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity.
PubMed ID: 25732826
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 401
- Mass: 45333
- Checksum: 24C1DC31E47B5B77
- Sequence:
MMGLGNGRRS MKSPPLVLAA LVACIIVLGF NYWIASSRSV DLQTRIMELE GRVRRAAAER GAVELKKNEF QGELEKQREQ LDKIQSSHNF QLESVNKLYQ DEKAVLVNNI TTGERLIRVL QDQLKTLQRN YGRLQQDVLQ FQKNQTNLER KFSYDLSQCI NQMKEVKEQC EERIEEVTKK GNEAVASRDL SENNDQRQQL QALSEPQPRL QAAGLPHTEV PQGKGNVLGN SKSQTPAPSS EVVLDSKRQV EKEETNEIQV VNEEPQRDRL PQEPGREQVV EDRPVGGRGF GGAGELGQTP QVQAALSVSQ ENPEMEGPER DQLVIPDGQE EEQEAAGEGR NQQKLRGEDD YNMDENEAES ETDKQAALAG NDRNIDVFNV EDQKRDTINL LDQREKRNHT L