Details for: TAOK3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 507.5051
Cell Significance Index: -78.9400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 223.7393
Cell Significance Index: -56.7500 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 213.0611
Cell Significance Index: -87.7700 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 178.4338
Cell Significance Index: -72.4900 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 155.7004
Cell Significance Index: -80.0900 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 127.2685
Cell Significance Index: -85.4000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 76.6280
Cell Significance Index: -73.1600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 66.1743
Cell Significance Index: -81.5900 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 27.6984
Cell Significance Index: -74.2000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 26.1472
Cell Significance Index: -80.3100 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 21.9548
Cell Significance Index: -48.0500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 21.0312
Cell Significance Index: -82.9900 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 5.1289
Cell Significance Index: 61.1400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.2591
Cell Significance Index: 453.1800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.2000
Cell Significance Index: 436.5900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.0366
Cell Significance Index: 730.4800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.8930
Cell Significance Index: 145.2700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 1.7366
Cell Significance Index: 43.4100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.6311
Cell Significance Index: 294.0500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.4104
Cell Significance Index: 86.6900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.3581
Cell Significance Index: 167.0000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.2344
Cell Significance Index: 35.5700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.2279
Cell Significance Index: 77.3900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.0236
Cell Significance Index: 707.9500 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.9325
Cell Significance Index: 18.2000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.8428
Cell Significance Index: 38.2000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.8157
Cell Significance Index: 80.6900 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.5596
Cell Significance Index: 13.4200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.5519
Cell Significance Index: 24.4100 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.5006
Cell Significance Index: 4.6100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.4702
Cell Significance Index: 13.1400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.4137
Cell Significance Index: 26.6900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.3773
Cell Significance Index: 44.5000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.3593
Cell Significance Index: 24.1600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.3268
Cell Significance Index: 12.3800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2991
Cell Significance Index: 32.5300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2370
Cell Significance Index: 104.8000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2029
Cell Significance Index: 183.2300 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.1762
Cell Significance Index: 2.6400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1594
Cell Significance Index: 7.4900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1569
Cell Significance Index: 85.6700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1157
Cell Significance Index: 217.8900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.1084
Cell Significance Index: 5.6900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1015
Cell Significance Index: 1.7400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0806
Cell Significance Index: 15.3400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0789
Cell Significance Index: 35.7900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0789
Cell Significance Index: 10.8400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0628
Cell Significance Index: 3.2600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0455
Cell Significance Index: 69.9900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0390
Cell Significance Index: 1.3700 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.0383
Cell Significance Index: 0.4800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0228
Cell Significance Index: 41.9800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0221
Cell Significance Index: 14.0200 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 0.0115
Cell Significance Index: 0.1900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0049
Cell Significance Index: 6.6200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0067
Cell Significance Index: -4.9000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0161
Cell Significance Index: -0.4300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0309
Cell Significance Index: -23.4000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0392
Cell Significance Index: -24.4500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0492
Cell Significance Index: -36.4100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0828
Cell Significance Index: -12.0400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0854
Cell Significance Index: -48.1700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1019
Cell Significance Index: -10.4100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1144
Cell Significance Index: -19.5400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.1279
Cell Significance Index: -2.1600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1285
Cell Significance Index: -16.6100 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1366
Cell Significance Index: -17.5100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2345
Cell Significance Index: -10.9400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2611
Cell Significance Index: -75.1300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2893
Cell Significance Index: -60.9400 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.3014
Cell Significance Index: -5.5700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3137
Cell Significance Index: -36.5600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3470
Cell Significance Index: -39.6200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3849
Cell Significance Index: -9.9000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3982
Cell Significance Index: -29.6800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4124
Cell Significance Index: -47.2500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.4822
Cell Significance Index: -13.7600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.4930
Cell Significance Index: -14.4800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.5086
Cell Significance Index: -35.9700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.5565
Cell Significance Index: -31.2300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.6831
Cell Significance Index: -71.1300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.7044
Cell Significance Index: -36.6900 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.7473
Cell Significance Index: -10.4500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.7668
Cell Significance Index: -24.5600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.8226
Cell Significance Index: -65.1500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.8553
Cell Significance Index: -18.5300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.9006
Cell Significance Index: -19.1800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.9832
Cell Significance Index: -16.4600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -1.0839
Cell Significance Index: -27.6900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -1.1091
Cell Significance Index: -30.1900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -1.1605
Cell Significance Index: -24.6300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -1.1951
Cell Significance Index: -17.6400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -1.2717
Cell Significance Index: -17.3500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.3468
Cell Significance Index: -82.5700 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -1.4627
Cell Significance Index: -31.2700 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -1.5293
Cell Significance Index: -19.0700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.5339
Cell Significance Index: -41.1000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -1.5573
Cell Significance Index: -44.6400 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -1.5620
Cell Significance Index: -23.0600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.6164
Cell Significance Index: -51.4800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2736746229
Symbol: TAOK3_HUMAN
Name: Serine/threonine-protein kinase TAO3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10559204
Title: Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factor.
PubMed ID: 10559204
PubMed ID: 10924369
Title: Cloning of DPK, a novel dendritic cell-derived protein kinase activating the ERK1/ERK2 and JNK/SAPK pathways.
PubMed ID: 10924369
PubMed ID: 13679851
Title: Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38.
PubMed ID: 13679851
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 14996095
Title: SEREX identification of new tumour-associated antigens in cutaneous T-cell lymphoma.
PubMed ID: 14996095
PubMed ID: 11278723
Title: Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress.
PubMed ID: 11278723
PubMed ID: 17396146
Title: TAO kinases mediate activation of p38 in response to DNA damage.
PubMed ID: 17396146
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 20949042
Title: Signal transduction protein array analysis links LRRK2 to Ste20 kinases and PKC zeta that modulate neuronal plasticity.
PubMed ID: 20949042
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
Sequence Information:
- Length: 898
- Mass: 105406
- Checksum: AE7E30745B09763C
- Sequence:
MRKGVLKDPE IADLFYKDDP EELFIGLHEI GHGSFGAVYF ATNAHTSEVV AIKKMSYSGK QTHEKWQDIL KEVKFLRQLK HPNTIEYKGC YLKEHTAWLV MEYCLGSASD LLEVHKKPLQ EVEIAAITHG ALHGLAYLHS HALIHRDIKA GNILLTEPGQ VKLADFGSAS MASPANSFVG TPYWMAPEVI LAMDEGQYDG KVDIWSLGIT CIELAERKPP LFNMNAMSAL YHIAQNDSPT LQSNEWTDSF RRFVDYCLQK IPQERPTSAE LLRHDFVRRD RPLRVLIDLI QRTKDAVREL DNLQYRKMKK ILFQETRNGP LNESQEDEED SEHGTSLNRE MDSLGSNHSI PSMSVSTGSQ SSSVNSMQEV MDESSSELVM MHDDESTINS SSSVVHKKDH VFIRDEAGHG DPRPEPRPTQ SVQSQALHYR NRERFATIKS ASLVTRQIHE HEQENELREQ MSGYKRMRRQ HQKQLIALEN KLKAEMDEHR LKLQKEVETH ANNSSIELEK LAKKQVAIIE KEAKVAAADE KKFQQQILAQ QKKDLTTFLE SQKKQYKICK EKIKEEMNED HSTPKKEKQE RISKHKENLQ HTQAEEEAHL LTQQRLYYDK NCRFFKRKIM IKRHEVEQQN IREELNKKRT QKEMEHAMLI RHDESTRELE YRQLHTLQKL RMDLIRLQHQ TELENQLEYN KRRERELHRK HVMELRQQPK NLKAMEMQIK KQFQDTCKVQ TKQYKALKNH QLEVTPKNEH KTILKTLKDE QTRKLAILAE QYEQSINEMM ASQALRLDEA QEAECQALRL QLQQEMELLN AYQSKIKMQT EAQHERELQK LEQRVSLRRA HLEQKIEEEL AALQKERSER IKNLLERQER EIETFDMESL RMGFGNLVTL DFPKEDYR
Genular Protein ID: 1139719155
Symbol: G3V1Q8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
Sequence Information:
- Length: 438
- Mass: 53104
- Checksum: 8B7B608515E74821
- Sequence:
MSGYKRMRRQ HQKQLIALEN KLKAEMDEHR LKLQKEVETH ANNSSIELEK LAKKQVAIIE KEAKVAAADE KKFQQQILAQ QKKDLTTFLE SQKKQYKICK EKIKEEMNED HSTPKKEKQE RISKHKENLQ HTQAEEEAHL LTQQRLYYDK NCRFFKRKIM IKRHEVEQQN IREELNKKRT QKEMEHAMLI RHDESTRELE YRQLHTLQKL RMDLIRLQHQ TELENQLEYN KRRERELHRK HVMELRQQPK NLKAMEMQIK KQFQDTCKVQ TKQYKALKNH QLEVTPKNEH KTILKTLKDE QTRKLAILAE QYEQSINEMM ASQALRLDEA QEAECQALRL QLQQEMELLN AYQSKIKMQT EAQHERELQK LEQRVSLRRA HLEQKIEEEL AALQKERSER IKNLLERQER EIETFDMESL RMGFGNLVTL DFPKEDYR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.