Details for: CSAD

Gene ID: 51380

Symbol: CSAD

Ensembl ID: ENSG00000139631

Description: cysteine sulfinic acid decarboxylase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 234.3531
    Cell Significance Index: -36.4500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 139.4478
    Cell Significance Index: -35.3700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 74.8005
    Cell Significance Index: -35.3200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 74.3372
    Cell Significance Index: -30.2000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 66.5843
    Cell Significance Index: -34.2500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 31.5059
    Cell Significance Index: -30.0800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 29.9402
    Cell Significance Index: -36.9200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.6285
    Cell Significance Index: -33.8300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.3739
    Cell Significance Index: -36.9900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.5855
    Cell Significance Index: -26.3700
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 6.6595
    Cell Significance Index: 28.9900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.2545
    Cell Significance Index: -11.5000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.2150
    Cell Significance Index: 48.5000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.0794
    Cell Significance Index: 28.3700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.8487
    Cell Significance Index: 370.8500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.5994
    Cell Significance Index: 573.6900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.4218
    Cell Significance Index: 27.7500
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 1.3627
    Cell Significance Index: 17.1600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.3185
    Cell Significance Index: 81.0400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.2456
    Cell Significance Index: 34.8100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1929
    Cell Significance Index: 236.7300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.8765
    Cell Significance Index: 21.0200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.8238
    Cell Significance Index: 37.3400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8032
    Cell Significance Index: 725.2500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.7362
    Cell Significance Index: 56.5000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7336
    Cell Significance Index: 21.1400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.6533
    Cell Significance Index: 76.1300
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.6532
    Cell Significance Index: 10.4800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6161
    Cell Significance Index: 32.0100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4872
    Cell Significance Index: 79.2400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4836
    Cell Significance Index: 66.4100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.4783
    Cell Significance Index: 13.0200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4698
    Cell Significance Index: 31.5900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4630
    Cell Significance Index: 50.3700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.4438
    Cell Significance Index: 7.4800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.3945
    Cell Significance Index: 22.1400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3048
    Cell Significance Index: 39.0700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2727
    Cell Significance Index: 26.9800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2577
    Cell Significance Index: 113.9500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.2039
    Cell Significance Index: 5.2400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2019
    Cell Significance Index: 13.9600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2014
    Cell Significance Index: 139.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1976
    Cell Significance Index: 24.3000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1909
    Cell Significance Index: 8.9000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1878
    Cell Significance Index: 35.7300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1858
    Cell Significance Index: 349.8700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1618
    Cell Significance Index: 29.1700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1488
    Cell Significance Index: 19.2300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1465
    Cell Significance Index: 93.0200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1369
    Cell Significance Index: 4.8100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1255
    Cell Significance Index: 6.5900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1227
    Cell Significance Index: 67.0000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1000
    Cell Significance Index: 153.9600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0960
    Cell Significance Index: 177.0200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0855
    Cell Significance Index: 4.0200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0787
    Cell Significance Index: 35.7200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0703
    Cell Significance Index: 5.2400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0499
    Cell Significance Index: 1.4300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0402
    Cell Significance Index: 54.7100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0077
    Cell Significance Index: -0.5400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0080
    Cell Significance Index: -5.8900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0121
    Cell Significance Index: -0.7600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0356
    Cell Significance Index: -26.9400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0396
    Cell Significance Index: -29.3100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0536
    Cell Significance Index: -2.3700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0597
    Cell Significance Index: -2.2600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0600
    Cell Significance Index: -33.8500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0620
    Cell Significance Index: -38.7400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0805
    Cell Significance Index: -13.7400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1030
    Cell Significance Index: -14.9700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1040
    Cell Significance Index: -1.7400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1057
    Cell Significance Index: -10.8000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1120
    Cell Significance Index: -32.2200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1161
    Cell Significance Index: -6.0500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1238
    Cell Significance Index: -7.9900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1384
    Cell Significance Index: -4.8100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1786
    Cell Significance Index: -37.6200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.1958
    Cell Significance Index: -2.8900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1970
    Cell Significance Index: -20.5100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2046
    Cell Significance Index: -24.1300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2341
    Cell Significance Index: -26.8300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2528
    Cell Significance Index: -6.7800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2778
    Cell Significance Index: -4.7600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3059
    Cell Significance Index: -6.5200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3293
    Cell Significance Index: -6.8300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4069
    Cell Significance Index: -32.2300
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.4084
    Cell Significance Index: -5.8700
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.4088
    Cell Significance Index: -5.7300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.4253
    Cell Significance Index: -9.2200
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.4325
    Cell Significance Index: -5.3700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.4352
    Cell Significance Index: -10.0600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4406
    Cell Significance Index: -27.0100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4495
    Cell Significance Index: -12.8900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4547
    Cell Significance Index: -5.4200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4603
    Cell Significance Index: -15.0700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5037
    Cell Significance Index: -16.0400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.5442
    Cell Significance Index: -8.0400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.5533
    Cell Significance Index: -10.9400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.5781
    Cell Significance Index: -12.1000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5979
    Cell Significance Index: -12.6900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Enzyme activity:** CSAD is a decarboxylase enzyme that catalyzes the conversion of cysteine sulfinic acid to cysteine sulfinate, which is then converted into hypotaurine and taurine. 2. **Cellular localization:** CSAD is primarily found in the cytoplasm of various cell types, including hematopoietic cells, smooth muscle fibers, and immune cells. 3. **Expression patterns:** CSAD is significantly expressed in hematopoietic oligopotent progenitor cells, polychromatophilic erythroblasts, and CD8-alpha-beta-positive, alpha-beta intraepithelial T cells. 4. **Protein structure:** The CSAD protein consists of a single polypeptide chain with a molecular weight of approximately 30 kDa. **Pathways and Functions:** 1. **L-cysteine catabolic process:** CSAD is involved in the degradation of L-cysteine, converting it into hypotaurine and taurine, which are essential components of various biomolecules. 2. **Metabolism of amino acids and derivatives:** CSAD plays a role in the metabolism of amino acids and derivatives, including the breakdown of cysteine and homocysteine. 3. **Pyridoxal phosphate binding:** CSAD is a pyridoxal phosphate-binding enzyme, which suggests its involvement in the regulation of enzymatic activity. 4. **Sulfur amino acid metabolism:** CSAD is involved in the metabolism of sulfur-containing amino acids, including cysteine and homocysteine. **Clinical Significance:** 1. **Hematological disorders:** Abnormalities in CSAD expression or function may contribute to hematological disorders, such as anemia and leukemia. 2. **Immunological disorders:** CSAD may play a role in the development of immunological disorders, such as autoimmune diseases and allergies. 3. **Neurological disorders:** CSAD has been implicated in the pathogenesis of neurological disorders, including Alzheimer's disease and Parkinson's disease. 4. **Cancer:** CSAD may have a role in the development and progression of cancer, particularly in hematological malignancies. In conclusion, CSAD is a complex enzyme with a multifaceted role in amino acid metabolism, immune function, and cellular regulation. Further research is necessary to fully elucidate the functions of CSAD and its implications in human disease.

Genular Protein ID: 3036283685

Symbol: CSAD_HUMAN

Name: Cysteine sulfinic acid decarboxylase

UniProtKB Accession Codes:

Q9Y600 A8K0U4 Q4QQH9 Q9UNJ5 Q9Y601

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 13 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 3 EMBL 9 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 7 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 1 RefSeq 3 Rhea 3 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 26327310

Title: Mammalian CSAD and GADL1 have distinct biochemical properties and patterns of brain expression.

PubMed ID: 26327310

DOI: 10.1016/j.neuint.2015.08.013

Sequence Information:

  • Length: 493
  • Mass: 55023
  • Checksum: 09BA2028D942016E
  • Sequence:
    • MADSEALPSL AGDPVAVEAL LRAVFGVVVD EAIQKGTSVS QKVCEWKEPE ELKQLLDLEL 
RSQGESQKQI LERCRAVIRY SVKTGHPRFF NQLFSGLDPH ALAGRIITES LNTSQYTYEI 
APVFVLMEEE VLRKLRALVG WSSGDGIFCP GGSISNMYAV NLARYQRYPD CKQRGLRTLP 
PLALFTSKEC HYSIQKGAAF LGLGTDSVRV VKADERGKMV PEDLERQIGM AEAEGAVPFL 
VSATSGTTVL GAFDPLEAIA DVCQRHGLWL HVDAAWGGSV LLSQTHRHLL DGIQRADSVA 
WNPHKLLAAG LQCSALLLQD TSNLLKRCHG SQASYLFQQD KFYDVALDTG DKVVQCGRRV 
DCLKLWLMWK AQGDQGLERR IDQAFVLARY LVEEMKKREG FELVMEPEFV NVCFWFVPPS 
LRGKQESPDY HERLSKVAPV LKERMVKEGS MMIGYQPHGT RGNFFRVVVA NSALTCADMD 
FLLNELERLG QDL

Genular Protein ID: 3931811870

Symbol: Q86V02_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q86V02

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 582
  • Mass: 64253
  • Checksum: B34192D92E4CAB5B
  • Sequence:
    • HGLRATEALP SVRTTLRSLG LAPTCQARPP AGSLAARRLL QAPAHPANPT AAAAPTGTEG 
GSHLWSQHVG RPRSYLCTLP PALLSREILM ADSEALPSLA GDPVAVEALL RAVFGVVVDE 
AIQKGTSVSQ KVCEWKEPEE LKQLLDLELR SQGESQKQIL ERCRAVIRYS VKTGHPRFFN 
QLFSGLDPHA LAGRIITESL NTSQYTYEIA PVFVLMEEEV LRKLRALVGW SSGDGIFCPG 
GSISNMYAVN LARYQRYPDC KQRGLRTLPP LALFTSKECH YSIQKGAAFL GLGTDSVRVV 
KADERGKMVP EDLDRQIGMA EAEGAVPFLV SATSGTTVLG AFDPLEAIAD VCQRHGLWLH 
VDAAWGGSVL LSQTHRHLLD GIQRADSVAW NPHKLLAAGL QCSALLLQDT SNLLKRCHGS 
QASYLFQQDK FYDVALDTGD KVVQCGRRVD CLKLWLMWKA QGDQGLERRI DQAFVLARYL 
VEEMKKREGF ELVMEPEFVN VCFWFVPPSL RGKQESPDYH ERLSKVAPVL KERMVKEGSM 
MIGYQPHGTR GNFFRVVVAN SALTCADMDF LLNELERLGQ DL

Genular Protein ID: 791601446

Symbol: Q96JQ3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96JQ3

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 2 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 260
  • Mass: 29223
  • Checksum: 60FA2F37695D4CB1
  • Sequence:
    • MGAVPFLVSA TSGTTVLGAF DPLEAIADVC QRHGLWLHVD AAWGGSVLLS QTHRHLLDGI 
QRADSVAWNP HKLLAAGLQC SALLLQDTSN LLKRCHGSQA SYLFQQDKFY DVALDTGDKV 
VQCGRRVDCL KLWLMWKAQG DQGLERRIDQ AFVLARYLVE EMKKREGFEL VMEPEFVNVC 
FWFVPPSLRG KQESPDYHER LSKVAPVLKE RMVKEGSMMI GYQPHGTRGN FFRVVVANSA 
LTCADMDFLL NELERLGQDL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.