Details for: STK26
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 28.5533
Cell Significance Index: -11.6000 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 27.0031
Cell Significance Index: -13.8900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 12.7495
Cell Significance Index: -12.1700 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 4.5635
Cell Significance Index: -12.2300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 2.5005
Cell Significance Index: 475.8500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 2.1496
Cell Significance Index: 212.6400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.1373
Cell Significance Index: 57.0700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 2.0294
Cell Significance Index: 236.5000 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 1.5941
Cell Significance Index: 17.3300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 1.3662
Cell Significance Index: -2.9900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.3130
Cell Significance Index: 35.7400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 1.0868
Cell Significance Index: 29.0700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.0845
Cell Significance Index: 69.9700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.9187
Cell Significance Index: 55.1600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8436
Cell Significance Index: 761.7500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.8082
Cell Significance Index: 87.9100 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 0.6705
Cell Significance Index: 4.2800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6626
Cell Significance Index: 107.7600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4794
Cell Significance Index: 95.1300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.4253
Cell Significance Index: 54.5200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4054
Cell Significance Index: 28.0400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3577
Cell Significance Index: 7.7500 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.3435
Cell Significance Index: 4.8900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.2247
Cell Significance Index: 6.6000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1886
Cell Significance Index: 8.5500 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.1786
Cell Significance Index: 1.9000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.1708
Cell Significance Index: 20.1400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1577
Cell Significance Index: 86.1000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1529
Cell Significance Index: 18.8000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1322
Cell Significance Index: 3.8100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1203
Cell Significance Index: 21.6900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1116
Cell Significance Index: 3.1200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0655
Cell Significance Index: 3.4000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0634
Cell Significance Index: 28.0200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0148
Cell Significance Index: 0.3700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0008
Cell Significance Index: -0.6000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0012
Cell Significance Index: -0.7600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0055
Cell Significance Index: -10.3700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0080
Cell Significance Index: -0.2800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: -0.0089
Cell Significance Index: -6.1900 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0102
Cell Significance Index: -0.2600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0119
Cell Significance Index: -21.9200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0121
Cell Significance Index: -8.9000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0151
Cell Significance Index: -23.2100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0154
Cell Significance Index: -1.0900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0175
Cell Significance Index: -23.7900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0188
Cell Significance Index: -13.9100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0221
Cell Significance Index: -12.4500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0230
Cell Significance Index: -4.6100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0251
Cell Significance Index: -1.1700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0260
Cell Significance Index: -16.2100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0277
Cell Significance Index: -9.9400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0293
Cell Significance Index: -13.2900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0310
Cell Significance Index: -1.7400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0369
Cell Significance Index: -10.6100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0376
Cell Significance Index: -5.4600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0460
Cell Significance Index: -2.1600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0461
Cell Significance Index: -7.8700 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0482
Cell Significance Index: -1.0000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0513
Cell Significance Index: -0.7000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0520
Cell Significance Index: -2.3000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0553
Cell Significance Index: -7.1500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0624
Cell Significance Index: -1.3300 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: -0.0660
Cell Significance Index: -0.4100 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.0667
Cell Significance Index: -0.4300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0687
Cell Significance Index: -7.8800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0742
Cell Significance Index: -3.7500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0825
Cell Significance Index: -11.3300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0831
Cell Significance Index: -17.5100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0898
Cell Significance Index: -6.7000 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.0963
Cell Significance Index: -1.7800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0998
Cell Significance Index: -3.7800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1010
Cell Significance Index: -10.3200 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.1140
Cell Significance Index: -1.6200 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1231
Cell Significance Index: -5.0500 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: -0.1281
Cell Significance Index: -0.8500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1301
Cell Significance Index: -13.5500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1535
Cell Significance Index: -10.3200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1584
Cell Significance Index: -12.5500 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.1632
Cell Significance Index: -2.4600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1821
Cell Significance Index: -13.9800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1844
Cell Significance Index: -3.8600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1905
Cell Significance Index: -11.6800 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.1964
Cell Significance Index: -8.5400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2063
Cell Significance Index: -10.7500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2131
Cell Significance Index: -13.4300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2287
Cell Significance Index: -14.0600 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.2487
Cell Significance Index: -2.2900 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2590
Cell Significance Index: -6.8100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2813
Cell Significance Index: -14.7700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.2846
Cell Significance Index: -9.8900 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: -0.3014
Cell Significance Index: -2.8900 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.3040
Cell Significance Index: -5.0100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3069
Cell Significance Index: -9.8300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3334
Cell Significance Index: -5.5800 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: -0.3361
Cell Significance Index: -3.3700 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3372
Cell Significance Index: -12.3800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3443
Cell Significance Index: -12.0600 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.3570
Cell Significance Index: -5.3500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3605
Cell Significance Index: -10.3400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2794865805
Symbol: STK26_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11641781
Title: MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway.
PubMed ID: 11641781
PubMed ID: 11306563
Title: Cloning and characterization of MST4, a novel Ste20-like kinase.
PubMed ID: 11306563
PubMed ID: 11741893
Title: Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties.
PubMed ID: 11741893
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15037601
Title: YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta.
PubMed ID: 15037601
PubMed ID: 17360971
Title: PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway.
PubMed ID: 17360971
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19370760
Title: Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein.
PubMed ID: 19370760
DOI: 10.1002/humu.20996
PubMed ID: 18782753
Title: A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.
PubMed ID: 18782753
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20332113
Title: CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation.
PubMed ID: 20332113
DOI: 10.1242/jcs.061341
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 27807006
Title: RHO binding to FAM65A regulates Golgi reorientation during cell migration.
PubMed ID: 27807006
DOI: 10.1242/jcs.198614
PubMed ID: 29232556
Title: MST4 phosphorylation of ATG4B regulates autophagic activity, tumorigenicity, and radioresistance in glioblastoma.
PubMed ID: 29232556
PubMed ID: 20730082
Title: Structural comparison of human mammalian ste20-like kinases.
PubMed ID: 20730082
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
Sequence Information:
- Length: 416
- Mass: 46529
- Checksum: 3E31B7E3CBDA5768
- Sequence:
MAHSPVAVQV PGMQNNIADP EELFTKLERI GKGSFGEVFK GIDNRTQQVV AIKIIDLEEA EDEIEDIQQE ITVLSQCDSS YVTKYYGSYL KGSKLWIIME YLGGGSALDL LRAGPFDEFQ IATMLKEILK GLDYLHSEKK IHRDIKAANV LLSEQGDVKL ADFGVAGQLT DTQIKRNTFV GTPFWMAPEV IQQSAYDSKA DIWSLGITAI ELAKGEPPNS DMHPMRVLFL IPKNNPPTLV GDFTKSFKEF IDACLNKDPS FRPTAKELLK HKFIVKNSKK TSYLTELIDR FKRWKAEGHS DDESDSEGSD SESTSRENNT HPEWSFTTVR KKPDPKKVQN GAEQDLVQTL SCLSMIITPA FAELKQQDEN NASRNQAIEE LEKSIAVAEA ACPGITDKMV KKLIEKFQKC SADESP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.