Details for: PFKL

Gene ID: 5211

Symbol: PFKL

Ensembl ID: ENSG00000141959

Description: phosphofructokinase, liver type

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 226.8794
    Cell Significance Index: -35.2900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 137.3976
    Cell Significance Index: -34.8500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 91.4199
    Cell Significance Index: -37.1400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 87.2231
    Cell Significance Index: -41.1800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 80.9510
    Cell Significance Index: -41.6400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 39.5604
    Cell Significance Index: -37.7700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 32.7262
    Cell Significance Index: -40.3500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.9533
    Cell Significance Index: -34.7000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.4408
    Cell Significance Index: -35.1400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.5245
    Cell Significance Index: -41.5300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.6768
    Cell Significance Index: -18.9900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.6351
    Cell Significance Index: 286.6200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.0787
    Cell Significance Index: 134.1100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.8059
    Cell Significance Index: 93.8100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.7144
    Cell Significance Index: 89.3000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.4987
    Cell Significance Index: 32.4700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.4514
    Cell Significance Index: 261.6400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.4208
    Cell Significance Index: 231.0800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.4134
    Cell Significance Index: 97.7500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.2928
    Cell Significance Index: 11.9100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.2825
    Cell Significance Index: 700.4000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.2628
    Cell Significance Index: 1140.2100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.1344
    Cell Significance Index: 139.4900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.0733
    Cell Significance Index: 126.5700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.0527
    Cell Significance Index: 28.1100
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.9700
    Cell Significance Index: 7.7500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.9598
    Cell Significance Index: 27.6600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.9491
    Cell Significance Index: 27.8800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9043
    Cell Significance Index: 179.4600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.9037
    Cell Significance Index: 40.9600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.7775
    Cell Significance Index: 36.2500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.7357
    Cell Significance Index: 20.5600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6806
    Cell Significance Index: 136.5300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.6689
    Cell Significance Index: 35.1200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6532
    Cell Significance Index: 64.6200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5048
    Cell Significance Index: 69.3200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4368
    Cell Significance Index: 20.5300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.4218
    Cell Significance Index: 54.0700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4153
    Cell Significance Index: 183.6200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3995
    Cell Significance Index: 76.0300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3938
    Cell Significance Index: 50.8800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.3925
    Cell Significance Index: 8.3600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3544
    Cell Significance Index: 127.1200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.3512
    Cell Significance Index: 8.7800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.3438
    Cell Significance Index: 9.0400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.3345
    Cell Significance Index: 24.9300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.3179
    Cell Significance Index: 2.6700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.3117
    Cell Significance Index: 4.6700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3099
    Cell Significance Index: 8.4400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.2885
    Cell Significance Index: 9.2400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2012
    Cell Significance Index: 7.0700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1454
    Cell Significance Index: 10.2800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1125
    Cell Significance Index: 3.9100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1109
    Cell Significance Index: 6.9900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0757
    Cell Significance Index: 142.5700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0607
    Cell Significance Index: 44.4900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0524
    Cell Significance Index: 1.2100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0436
    Cell Significance Index: 67.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0300
    Cell Significance Index: 55.2500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0232
    Cell Significance Index: 14.7200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0168
    Cell Significance Index: 22.8800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0005
    Cell Significance Index: -0.0100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0129
    Cell Significance Index: -9.7400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0193
    Cell Significance Index: -1.9700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0237
    Cell Significance Index: -4.0400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0461
    Cell Significance Index: -6.7100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0492
    Cell Significance Index: -22.3200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0514
    Cell Significance Index: -38.0900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0684
    Cell Significance Index: -1.1500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0739
    Cell Significance Index: -41.6900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0745
    Cell Significance Index: -46.5300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1172
    Cell Significance Index: -33.7200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1798
    Cell Significance Index: -4.8100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1936
    Cell Significance Index: -22.1800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2202
    Cell Significance Index: -4.6100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2204
    Cell Significance Index: -46.4300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2215
    Cell Significance Index: -2.6400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2523
    Cell Significance Index: -29.4000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2690
    Cell Significance Index: -21.3000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2693
    Cell Significance Index: -16.5500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2858
    Cell Significance Index: -3.9000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3261
    Cell Significance Index: -21.9300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3436
    Cell Significance Index: -35.7800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3736
    Cell Significance Index: -28.6700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3940
    Cell Significance Index: -11.3000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3992
    Cell Significance Index: -22.4000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4608
    Cell Significance Index: -13.1500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.5042
    Cell Significance Index: -12.8800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5991
    Cell Significance Index: -36.7300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6485
    Cell Significance Index: -28.6900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.7469
    Cell Significance Index: -9.5700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.7561
    Cell Significance Index: -22.2700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.7662
    Cell Significance Index: -20.5300
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.7747
    Cell Significance Index: -13.6900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7809
    Cell Significance Index: -29.5700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.8008
    Cell Significance Index: -17.5400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.8687
    Cell Significance Index: -18.0200
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.9159
    Cell Significance Index: -7.0600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.9178
    Cell Significance Index: -29.2300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.9862
    Cell Significance Index: -34.5500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PFKL is a type II phosphofructokinase, distinct from the more commonly studied type I. This enzyme is characterized by its high affinity for fructose-6-phosphate and its ability to generate fructose-1,6-bisphosphate, a crucial intermediate in glycolysis. PFKL is also known for its ability to regulate the glycolytic pathway in response to changes in glucose levels and energy demands. **Pathways and Functions:** PFKL plays a central role in the glycolytic pathway, which is a vital process for energy production in cells. The enzyme catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, a step that is essential for the generation of ATP. PFKL is also involved in the regulation of insulin secretion and glucose metabolism, highlighting its importance in maintaining glucose homeostasis. In addition to its role in glycolysis, PFKL has been implicated in the regulation of immune responses. The enzyme is expressed in various immune cells, including myeloid leukocytes and early pro-B cells, suggesting its involvement in the regulation of immune cell function and cytokine production. **Clinical Significance:** Dysregulation of PFKL has been implicated in various diseases, including diabetes, obesity, and cancer. In diabetes, PFKL has been shown to be overexpressed in pancreatic islet cells, contributing to insulin resistance and glucose intolerance. In cancer, PFKL has been found to be overexpressed in certain tumor types, including colon cancer, where it contributes to tumor growth and metastasis. Furthermore, PFKL has been identified as a potential therapeutic target for the treatment of metabolic disorders. Inhibitors of PFKL have been shown to improve insulin sensitivity and glucose metabolism in animal models, suggesting its potential as a therapeutic agent for the treatment of diabetes and other metabolic disorders. **Conclusion:** In conclusion, PFKL is a critical enzyme in the glycolytic pathway, playing a central role in energy production and glucose metabolism. Its expression in various cell types, including immune cells, highlights its importance in regulating immune responses. The dysregulation of PFKL has been implicated in various diseases, including diabetes, obesity, and cancer, making it a potential therapeutic target for the treatment of metabolic disorders. Further research is needed to fully elucidate the role of PFKL in human disease and to develop effective therapeutic strategies for the treatment of metabolic disorders.

Genular Protein ID: 3297746196

Symbol: PFKAL_HUMAN

Name: 6-phosphofructokinase type B

UniProtKB Accession Codes:

P17858 Q96A64 Q96IH4 Q9BR91

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CPTAC 2 CTD 1 ChEBI 18 ChEMBL 1 ChiTaRS 1 ComplexPortal 4 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 26 EMDB 1 Ensembl 1 ExpressionAtlas 1 GO 22 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 Rhea 1 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2533063

Title: The primary structure of human liver type phosphofructokinase and its comparison with other types of PFK.

PubMed ID: 2533063

DOI: 10.1089/dna.1989.8.733

PubMed ID: 2139864

Title: The structure of the human liver-type phosphofructokinase gene.

PubMed ID: 2139864

DOI: 10.1016/0888-7543(90)90517-x

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 22923583

Title: Phosphofructokinase 1 glycosylation regulates cell growth and metabolism.

PubMed ID: 22923583

DOI: 10.1126/science.1222278

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 780
  • Mass: 85018
  • Checksum: 0D686CE074E9626D
  • Sequence:
    • MAAVDLEKLR ASGAGKAIGV LTSGGDAQGM NAAVRAVTRM GIYVGAKVFL IYEGYEGLVE 
GGENIKQANW LSVSNIIQLG GTIIGSARCK AFTTREGRRA AAYNLVQHGI TNLCVIGGDG 
SLTGANIFRS EWGSLLEELV AEGKISETTA RTYSHLNIAG LVGSIDNDFC GTDMTIGTDS 
ALHRIMEVID AITTTAQSHQ RTFVLEVMGR HCGYLALVSA LASGADWLFI PEAPPEDGWE 
NFMCERLGET RSRGSRLNII IIAEGAIDRN GKPISSSYVK DLVVQRLGFD TRVTVLGHVQ 
RGGTPSAFDR ILSSKMGMEA VMALLEATPD TPACVVTLSG NQSVRLPLME CVQMTKEVQK 
AMDDKRFDEA TQLRGGSFEN NWNIYKLLAH QKPPKEKSNF SLAILNVGAP AAGMNAAVRS 
AVRTGISHGH TVYVVHDGFE GLAKGQVQEV GWHDVAGWLG RGGSMLGTKR TLPKGQLESI 
VENIRIYGIH ALLVVGGFEA YEGVLQLVEA RGRYEELCIV MCVIPATISN NVPGTDFSLG 
SDTAVNAAME SCDRIKQSAS GTKRRVFIVE TMGGYCGYLA TVTGIAVGAD AAYVFEDPFN 
IHDLKVNVEH MTEKMKTDIQ RGLVLRNEKC HDYYTTEFLY NLYSSEGKGV FDCRTNVLGH 
LQQGGAPTPF DRNYGTKLGV KAMLWLSEKL REVYRKGRVF ANAPDSACVI GLKKKAVAFS 
PVTELKKDTD FEHRMPREQW WLSLRLMLKM LAQYRISMAA YVSGELEHVT RRTLSMDKGF

Genular Protein ID: 3586033404

Symbol: Q7L2M7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7L2M7

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 6 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 12 Gene3D 2 InterPro 5 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 Rhea 1 SUPFAM 1 UniPathway 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 568
  • Mass: 62640
  • Checksum: 299BE2321A79AE7F
  • Sequence:
    • GYLALVSALA SGADWLFIPE APPEDGWENF MCERLGETRS RGSRLNIIII AEGAIDRNGK 
PISSSYVKDL VVQRLGFDTR VTVLGHVQRG GTPSAFDRIL SSKMGMEAVM ALLEATPDTP 
ACVVTLSGNQ SVRLPLMECV QMTKEVQKAM DDKRFDEATQ LRGGSFENNW NIYKLLAHQK 
PPKEKSNFSL AILNVGAPAA GMNAAVRSAV RTGISHGHTV YVVHDGFEGL AKGQVQEVGW 
HDVAGWLGRG GSMLGTKRTL PKGQLESIVE NIRIYGIHAL LVVGGFEAYE GVLQLVEARG 
RYEELCIVMC VIPATISNNV PGTDFSLGSD TAVNAAMESC DRIKQSASGT KRRVFIVETM 
GGYCGYLATV TGIAVGADAA YVFEDPFNIH DLKVNVEHMT EKMKTDIQRG LVLRNEKCHD 
YYTTEFLYNL YSSEGKGVFD CRTNVLGHLQ QGGAPTPFDR NYGTKLGVKA MLWLSEKLRE 
VYRKGRVFAN APDSACVIGL KKKAVAFSPV TELKKDTDFE HRMPREQWWL SLRLMLKMLA 
QYRISMAAYV SGELEHVTRR TLSMDKGF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.