Details for: PHKA2

Gene ID: 5256

Symbol: PHKA2

Ensembl ID: ENSG00000044446

Description: phosphorylase kinase regulatory subunit alpha 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 108.2000
    Cell Significance Index: -16.8300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 64.4606
    Cell Significance Index: -16.3500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 37.9316
    Cell Significance Index: -15.4100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 37.6868
    Cell Significance Index: -15.5300
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 27.6891
    Cell Significance Index: -18.5800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 16.2033
    Cell Significance Index: -15.4700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 14.1205
    Cell Significance Index: -17.4100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.6409
    Cell Significance Index: -17.7900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.4193
    Cell Significance Index: -16.6500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.4817
    Cell Significance Index: -17.6900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.3544
    Cell Significance Index: -9.5300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.4028
    Cell Significance Index: 23.6300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3180
    Cell Significance Index: 261.5700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.2823
    Cell Significance Index: 34.2400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.2049
    Cell Significance Index: 32.2900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.1917
    Cell Significance Index: 117.8900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.1249
    Cell Significance Index: 86.3300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.1157
    Cell Significance Index: 31.1800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6982
    Cell Significance Index: 75.9500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.6886
    Cell Significance Index: 30.4600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6670
    Cell Significance Index: 40.0400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.6663
    Cell Significance Index: 25.2300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6573
    Cell Significance Index: 106.9100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6451
    Cell Significance Index: 129.4000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5480
    Cell Significance Index: 15.7900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5069
    Cell Significance Index: 181.8000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4690
    Cell Significance Index: 10.1600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4280
    Cell Significance Index: 28.7800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4132
    Cell Significance Index: 18.7300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3859
    Cell Significance Index: 266.9100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.3679
    Cell Significance Index: 5.0200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3553
    Cell Significance Index: 24.5700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3111
    Cell Significance Index: 280.8700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2700
    Cell Significance Index: 15.1500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2436
    Cell Significance Index: 6.0900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2245
    Cell Significance Index: 11.6600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.2179
    Cell Significance Index: 13.4000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1724
    Cell Significance Index: 23.6800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1443
    Cell Significance Index: 63.7800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1365
    Cell Significance Index: 24.6100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0954
    Cell Significance Index: 6.1600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0817
    Cell Significance Index: 1.7400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0749
    Cell Significance Index: 9.2100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0689
    Cell Significance Index: 2.4200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0684
    Cell Significance Index: 37.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0623
    Cell Significance Index: 2.9000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0460
    Cell Significance Index: 7.8600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0400
    Cell Significance Index: 0.5900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0385
    Cell Significance Index: 72.5700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0380
    Cell Significance Index: 24.1400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.0366
    Cell Significance Index: 0.5400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0286
    Cell Significance Index: 0.4900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0177
    Cell Significance Index: 1.2500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0160
    Cell Significance Index: 29.4800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0149
    Cell Significance Index: 22.8800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0082
    Cell Significance Index: 3.7100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0013
    Cell Significance Index: -0.1500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0049
    Cell Significance Index: -6.7000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0141
    Cell Significance Index: -2.0500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0159
    Cell Significance Index: -11.6400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0176
    Cell Significance Index: -13.0100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0194
    Cell Significance Index: -14.7000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0194
    Cell Significance Index: -0.5200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0214
    Cell Significance Index: -2.7400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0242
    Cell Significance Index: -0.5800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0281
    Cell Significance Index: -15.8200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0311
    Cell Significance Index: -19.3900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0343
    Cell Significance Index: -3.5000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0445
    Cell Significance Index: -1.2700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0499
    Cell Significance Index: -14.3500
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.0653
    Cell Significance Index: -0.5800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0786
    Cell Significance Index: -9.0100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0826
    Cell Significance Index: -10.6700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0849
    Cell Significance Index: -2.3100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0865
    Cell Significance Index: -2.2800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0894
    Cell Significance Index: -18.8200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0909
    Cell Significance Index: -4.2700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1028
    Cell Significance Index: -6.4800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1033
    Cell Significance Index: -12.0400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1276
    Cell Significance Index: -2.4900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1426
    Cell Significance Index: -14.8500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1430
    Cell Significance Index: -4.5800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1468
    Cell Significance Index: -3.0500
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.1572
    Cell Significance Index: -1.9800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1607
    Cell Significance Index: -3.4100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1620
    Cell Significance Index: -12.0700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1661
    Cell Significance Index: -3.5500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1805
    Cell Significance Index: -9.4000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1868
    Cell Significance Index: -9.8100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2066
    Cell Significance Index: -5.3100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2068
    Cell Significance Index: -16.3800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2116
    Cell Significance Index: -12.9700
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.2487
    Cell Significance Index: -3.9900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2727
    Cell Significance Index: -4.1100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2821
    Cell Significance Index: -4.0400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2920
    Cell Significance Index: -9.3000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2948
    Cell Significance Index: -6.8100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3016
    Cell Significance Index: -10.4800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3019
    Cell Significance Index: -5.5800
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.3066
    Cell Significance Index: -4.3000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PHKA2 is a member of the phosphorylase kinase regulatory subunit family, which plays a pivotal role in the regulation of glycogen breakdown. The PHKA2 gene is characterized by its high expression levels in cells involved in energy metabolism, such as hepatocytes and cardiac myocytes. The gene is also highly expressed in neurons, particularly in glutamatergic cortical interneurons, suggesting a potential role in regulating neuronal energy metabolism. **Pathways and Functions:** PHKA2 is involved in several key pathways related to glycogen metabolism, including: 1. **Glycogen breakdown (glycogenolysis)**: PHKA2 regulates the activity of phosphorylase kinase, which catalyzes the breakdown of glycogen into glucose-1-phosphate. 2. **Glycogen metabolic process**: PHKA2 is involved in the regulation of glycogen synthesis and breakdown, ensuring proper energy homeostasis in cells. 3. **Carbohydrate metabolic process**: PHKA2 plays a crucial role in the regulation of glucose metabolism, including glycolysis, gluconeogenesis, and glycogen synthesis. 4. **Metabolism of carbohydrates**: PHKA2 is involved in the regulation of carbohydrate metabolism, including the breakdown of glycogen, glucose-6-phosphate, and fructose-1-phosphate. **Clinical Significance:** Dysregulation of PHKA2 has been implicated in various diseases, including: 1. **Diabetes**: PHKA2 mutations have been associated with impaired glycogen breakdown, leading to hyperglycemia and diabetes. 2. **Hypothyroidism**: PHKA2 is involved in the regulation of thyroid hormone metabolism, and its dysregulation can lead to hypothyroidism. 3. **Neurodegenerative diseases**: PHKA2 has been implicated in the regulation of neuronal energy metabolism, and its dysregulation may contribute to neurodegenerative diseases, such as Alzheimer's and Parkinson's. 4. **Cardiac diseases**: PHKA2 is involved in the regulation of cardiac energy metabolism, and its dysregulation may contribute to cardiac dysfunction and disease. In conclusion, PHKA2 plays a crucial role in regulating glycogen metabolism, energy homeostasis, and carbohydrate metabolism. Its dysregulation has been implicated in various diseases, highlighting the importance of PHKA2 in maintaining proper cellular function and overall health. Further research is needed to fully elucidate the mechanisms of PHKA2 and its clinical significance in human disease.

Genular Protein ID: 2073681509

Symbol: KPB2_HUMAN

Name: Phosphorylase b kinase regulatory subunit alpha, liver isoform

UniProtKB Accession Codes:

P46019 A8K1T1 Q6LAJ5 Q7Z6W0 Q96CR3 Q9UDA1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 42 Ensembl 1 GO 9 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7847371

Title: X-linked liver phosphorylase kinase deficiency is associated with mutations in the human liver phosphorylase kinase alpha subunit.

PubMed ID: 7847371

PubMed ID: 7549948

Title: Isolation of cDNA encoding the human liver phosphorylase kinase alpha subunit (PHKA2) and identification of a missense mutation of the PHKA2 gene in a family with liver phosphorylase kinase deficiency.

PubMed ID: 7549948

PubMed ID: 10330341

Title: Complete genomic structure and mutational spectrum of PHKA2 in patients with X-linked liver glycogenosis type I and II.

PubMed ID: 10330341

DOI: 10.1086/302399

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9600238

Title: Variability of biochemical and clinical phenotype in X-linked liver glycogenosis with mutations in the phosphorylase kinase PHKA2 gene.

PubMed ID: 9600238

DOI: 10.1007/s004390050715

PubMed ID: 8518797

Title: X-linked liver glycogenosis: localization and isolation of a candidate gene.

PubMed ID: 8518797

DOI: 10.1093/hmg/2.5.583

PubMed ID: 8226841

Title: The multiphosphorylation domain of the phosphorylase kinase alpha M and alpha L subunits is a hotspot of differential mRNA processing and of molecular evolution.

PubMed ID: 8226841

DOI: 10.1016/s0021-9258(19)49449-0

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 8733133

Title: X-linked liver glycogenosis type II (XLG II) is caused by mutations in PHKA2, the gene encoding the liver alpha subunit of phosphorylase kinase.

PubMed ID: 8733133

DOI: 10.1093/hmg/5.5.649

PubMed ID: 8733134

Title: Mutation hotspots in the PHKA2 gene in X-linked liver glycogenosis due to phosphorylase kinase deficiency with atypical activity in blood cells (XLG2).

PubMed ID: 8733134

DOI: 10.1093/hmg/5.5.653

PubMed ID: 17689125

Title: Glycogen storage disease type IX: High variability in clinical phenotype.

PubMed ID: 17689125

DOI: 10.1016/j.ymgme.2007.06.007

Sequence Information:

  • Length: 1235
  • Mass: 138408
  • Checksum: 6CA10CFFA86A582A
  • Sequence:
    • MRSRSNSGVR LDGYARLVQQ TILCYQNPVT GLLSASHEQK DAWVRDNIYS ILAVWGLGMA 
YRKNADRDED KAKAYELEQN VVKLMRGLLQ CMMRQVAKVE KFKHTQSTKD SLHAKYNTAT 
CGTVVGDDQW GHLQVDATSL FLLFLAQMTA SGLRIIFTLD EVAFIQNLVF YIEAAYKVAD 
YGMWERGDKT NQGIPELNAS SVGMAKAALE AIDELDLFGA HGGRKSVIHV LPDEVEHCQS 
ILFSMLPRAS TSKEIDAGLL SIISFPAFAV EDVNLVNVTK NEIISKLQGR YGCCRFLRDG 
YKTPREDPNR LHYDPAELKL FENIECEWPV FWTYFIIDGV FSGDAVQVQE YREALEGILI 
RGKNGIRLVP ELYAVPPNKV DEEYKNPHTV DRVPMGKVPH LWGQSLYILS SLLAEGFLAA 
GEIDPLNRRF STSVKPDVVV QVTVLAENNH IKDLLRKHGV NVQSIADIHP IQVQPGRILS 
HIYAKLGRNK NMNLSGRPYR HIGVLGTSKL YVIRNQIFTF TPQFTDQHHF YLALDNEMIV 
EMLRIELAYL CTCWRMTGRP TLTFPISRTM LTNDGSDIHS AVLSTIRKLE DGYFGGARVK 
LGNLSEFLTT SFYTYLTFLD PDCDEKLFDN ASEGTFSPDS DSDLVGYLED TCNQESQDEL 
DHYINHLLQS TSLRSYLPPL CKNTEDRHVF SAIHSTRDIL SVMAKAKGLE VPFVPMTLPT 
KVLSAHRKSL NLVDSPQPLL EKVPESDFQW PRDDHGDVDC EKLVEQLKDC SNLQDQADIL 
YILYVIKGPS WDTNLSGQHG VTVQNLLGEL YGKAGLNQEW GLIRYISGLL RKKVEVLAEA 
CTDLLSHQKQ LTVGLPPEPR EKIISAPLPP EELTKLIYEA SGQDISIAVL TQEIVVYLAM 
YVRAQPSLFV EMLRLRIGLI IQVMATELAR SLNCSGEEAS ESLMNLSPFD MKNLLHHILS 
GKEFGVERSV RPIHSSTSSP TISIHEVGHT GVTKTERSGI NRLRSEMKQM TRRFSADEQF 
FSVGQAASSS AHSSKSARSS TPSSPTGTSS SDSGGHHIGW GERQGQWLRR RRLDGAINRV 
PVGFYQRVWK ILQKCHGLSI DGYVLPSSTT REMTPHEIKF AVHVESVLNR VPQPEYRQLL 
VEAIMVLTLL SDTEMTSIGG IIHVDQIVQM ASQLFLQDQV SIGAMDTLEK DQATGICHFF 
YDSAPSGAYG TMTYLTRAVA SYLQELLPNS GCQMQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.