Details for: PLAUR

Gene ID: 5329

Symbol: PLAUR

Ensembl ID: ENSG00000011422

Description: plasminogen activator, urokinase receptor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 225.0792
    Cell Significance Index: -35.0100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 132.2723
    Cell Significance Index: -33.5500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 81.5493
    Cell Significance Index: -33.1300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 76.7385
    Cell Significance Index: -36.2300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 69.5199
    Cell Significance Index: -35.7600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 53.9066
    Cell Significance Index: -36.1700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 34.8890
    Cell Significance Index: -33.3100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 28.5655
    Cell Significance Index: -35.2200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.2444
    Cell Significance Index: -35.4800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.9406
    Cell Significance Index: -35.2800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 6.5250
    Cell Significance Index: 120.6000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.7199
    Cell Significance Index: -10.3300
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 3.1564
    Cell Significance Index: 20.9400
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 2.9477
    Cell Significance Index: 21.1700
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 2.8972
    Cell Significance Index: 17.9300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.3505
    Cell Significance Index: 122.1000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.1964
    Cell Significance Index: 59.7900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.0575
    Cell Significance Index: 265.8200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.0163
    Cell Significance Index: 57.8000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.9266
    Cell Significance Index: 90.5500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.8989
    Cell Significance Index: 54.7100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 1.2138
    Cell Significance Index: 32.4700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.0118
    Cell Significance Index: 21.9200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7476
    Cell Significance Index: 33.8900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.7080
    Cell Significance Index: 52.7700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5548
    Cell Significance Index: 302.9900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.5315
    Cell Significance Index: 18.6800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4746
    Cell Significance Index: 46.9500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4059
    Cell Significance Index: 366.5200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3579
    Cell Significance Index: 49.1500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3305
    Cell Significance Index: 62.8900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2828
    Cell Significance Index: 36.2500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.2191
    Cell Significance Index: 3.3900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1998
    Cell Significance Index: 32.5000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1948
    Cell Significance Index: 23.9500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1165
    Cell Significance Index: 12.6700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0484
    Cell Significance Index: 3.1300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0234
    Cell Significance Index: 4.7000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0174
    Cell Significance Index: 3.1500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0138
    Cell Significance Index: 6.0800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0090
    Cell Significance Index: 0.2300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0038
    Cell Significance Index: 0.2300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0016
    Cell Significance Index: -0.1600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0023
    Cell Significance Index: -1.6200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.0093
    Cell Significance Index: -0.1600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0123
    Cell Significance Index: -23.1900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0152
    Cell Significance Index: -2.6000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0200
    Cell Significance Index: -36.9000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0205
    Cell Significance Index: -12.8100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0215
    Cell Significance Index: -15.9000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0225
    Cell Significance Index: -34.6000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0239
    Cell Significance Index: -8.5900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0243
    Cell Significance Index: -18.4000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0298
    Cell Significance Index: -40.4900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0314
    Cell Significance Index: -0.4700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0365
    Cell Significance Index: -20.5700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0432
    Cell Significance Index: -27.4300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0460
    Cell Significance Index: -33.7300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0643
    Cell Significance Index: -4.4500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0694
    Cell Significance Index: -19.9600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0698
    Cell Significance Index: -8.0000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0756
    Cell Significance Index: -34.3200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0865
    Cell Significance Index: -17.1600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1109
    Cell Significance Index: -23.3600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1512
    Cell Significance Index: -7.0500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1548
    Cell Significance Index: -22.5100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1705
    Cell Significance Index: -19.8700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1708
    Cell Significance Index: -19.5000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2186
    Cell Significance Index: -6.1100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2470
    Cell Significance Index: -3.3700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.3014
    Cell Significance Index: -35.5500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3177
    Cell Significance Index: -22.4700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3371
    Cell Significance Index: -35.1000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3377
    Cell Significance Index: -18.9500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3475
    Cell Significance Index: -9.2800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3629
    Cell Significance Index: -22.2500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3792
    Cell Significance Index: -19.1600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3995
    Cell Significance Index: -24.5600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4331
    Cell Significance Index: -34.3000
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.4398
    Cell Significance Index: -4.8000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.4597
    Cell Significance Index: -35.2800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5024
    Cell Significance Index: -10.7000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.5271
    Cell Significance Index: -35.4400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.5308
    Cell Significance Index: -6.0300
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.5365
    Cell Significance Index: -4.6900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.5458
    Cell Significance Index: -28.4300
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.5512
    Cell Significance Index: -22.5900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.5743
    Cell Significance Index: -3.4700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.5875
    Cell Significance Index: -5.4100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6372
    Cell Significance Index: -28.1900
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.6414
    Cell Significance Index: -12.5400
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.6477
    Cell Significance Index: -9.2200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6975
    Cell Significance Index: -36.6200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7028
    Cell Significance Index: -22.5100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.7186
    Cell Significance Index: -5.8600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.7222
    Cell Significance Index: -26.5100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7648
    Cell Significance Index: -28.9600
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: -0.7770
    Cell Significance Index: -4.9600
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: -0.7849
    Cell Significance Index: -8.6700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.8025
    Cell Significance Index: -18.5400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Transmembrane Glycoprotein:** UPAR is a type of transmembrane glycoprotein, consisting of an extracellular domain, a transmembrane domain, and an intracellular domain. This unique structure enables it to interact with various ligands and signaling pathways. 2. **Receptor for Urokinase Plasminogen Activator:** UPAR acts as a receptor for urokinase plasminogen activator (uPA), a serine protease involved in fibrinolysis and tissue remodeling. 3. **Signaling Pathways:** UPAR interacts with multiple signaling pathways, including the PI3K/Akt, MAPK/ERK, and NF-κB pathways, modulating cellular responses to growth factors, cytokines, and other extracellular stimuli. 4. **Expression in Immune Cells:** UPAR is expressed in various immune cells, including macrophages, monocytes, and dendritic cells, where it plays a role in modulating immune responses and tissue inflammation. **Pathways and Functions:** 1. **Cell Adhesion and Migration:** UPAR regulates cell adhesion and migration by interacting with integrins, laminins, and other extracellular matrix components, facilitating cell movement and tissue remodeling. 2. **Immune Response:** UPAR modulates immune responses by interacting with various immune cells, including dendritic cells, macrophages, and T cells, influencing the production of cytokines and chemokines. 3. **Fibrinolysis and Tissue Remodeling:** UPAR plays a crucial role in fibrinolysis by regulating the activity of uPA, a key enzyme involved in the degradation of fibrin clots. 4. **Tumor Progression:** UPAR is overexpressed in various types of cancer, where it promotes tumor growth, invasion, and metastasis by interacting with growth factors, cytokines, and other signaling molecules. **Clinical Significance:** 1. **Cancer and Tumor Progression:** UPAR overexpression has been linked to poor prognosis and aggressive tumor behavior in various cancers, including breast, lung, and prostate cancers. 2. **Inflammatory Diseases:** UPAR is involved in the pathogenesis of inflammatory diseases, such as rheumatoid arthritis, atherosclerosis, and sepsis, where it modulates immune responses and tissue inflammation. 3. **Cardiovascular Diseases:** UPAR is associated with cardiovascular diseases, including hypertension, atherosclerosis, and cardiac remodeling, where it regulates cell adhesion, migration, and tissue remodeling. 4. **Neurological Disorders:** UPAR is implicated in neurological disorders, such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis, where it modulates neuroinflammation and neuronal survival. In conclusion, the PLAUR gene and its product, UPAR, play a multifaceted role in regulating immune responses, cell adhesion, migration, and tissue remodeling. Further research is needed to fully elucidate the mechanisms underlying UPAR's functions and to explore its potential as a therapeutic target in various diseases.

Genular Protein ID: 862958115

Symbol: UPAR_HUMAN

Name: Urokinase plasminogen activator surface receptor

UniProtKB Accession Codes:

Q03405 A8K409 Q12876 Q15845 Q16887 Q6IB52 Q9BWT0 Q9NYC8 Q9UD69 Q9UEA6 Q9UM92 Q9UMV0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 EMBL 23 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 34 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 11 PIR 3 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 3 RefSeq 4 SASBDB 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1689240

Title: Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.

PubMed ID: 1689240

DOI: 10.1002/j.1460-2075.1990.tb08132.x

PubMed ID: 1316922

Title: cDNA for Mo3, a monocyte activation antigen, encodes the human receptor for urokinase plasminogen activator.

PubMed ID: 1316922

PubMed ID: 8131971

Title: A novel urokinase receptor on monocyte-like macrophage cell line.

PubMed ID: 8131971

DOI: 10.1042/bst021395s

PubMed ID: 8392005

Title: An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator.

PubMed ID: 8392005

DOI: 10.1016/0014-5793(93)81763-p

PubMed ID: 8049431

Title: The structure of the urokinase-type plasminogen activator receptor gene.

PubMed ID: 8049431

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11051819

Title: cDNA cloning and sequencing of human urokinase receptor.

PubMed ID: 11051819

PubMed ID: 7605992

Title: A conserved TATA-less proximal promoter drives basal transcription from the urokinase-type plasminogen activator receptor gene.

PubMed ID: 7605992

PubMed ID: 2156852

Title: The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants.

PubMed ID: 2156852

DOI: 10.1016/s0021-9258(19)39348-2

PubMed ID: 9030717

Title: Cell-surface acceleration of urokinase-catalyzed receptor cleavage.

PubMed ID: 9030717

DOI: 10.1111/j.1432-1033.1997.0021a.x

PubMed ID: 7539799

Title: A novel form of dipeptidylpeptidase IV found in human serum. Isolation, characterization, and comparison with T lymphocyte membrane dipeptidylpeptidase IV (CD26).

PubMed ID: 7539799

DOI: 10.1074/jbc.270.23.14107

PubMed ID: 8394346

Title: Localization of the disulfide bonds in the NH2-terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchored membrane proteins.

PubMed ID: 8394346

DOI: 10.1016/s0021-9258(19)85366-8

PubMed ID: 10636902

Title: A urokinase receptor-associated protein with specific collagen binding properties.

PubMed ID: 10636902

DOI: 10.1074/jbc.275.3.1993

PubMed ID: 12376466

Title: Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: dependence on beta1 integrins and the cytoskeleton.

PubMed ID: 12376466

DOI: 10.1093/carcin/23.10.1593

PubMed ID: 15053742

Title: The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.

PubMed ID: 15053742

DOI: 10.1042/bj20040149

PubMed ID: 14764453

Title: LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration.

PubMed ID: 14764453

DOI: 10.1161/01.res.0000120862.79154.0f

PubMed ID: 15677461

Title: Regulation of urokinase receptor proteolytic function by the tetraspanin CD82.

PubMed ID: 15677461

DOI: 10.1074/jbc.m414189200

PubMed ID: 18718938

Title: Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR.

PubMed ID: 18718938

DOI: 10.1093/hmg/ddn256

PubMed ID: 23486467

Title: The soluble form of LR11 protein is a regulator of hypoxia-induced, urokinase-type plasminogen activator receptor (uPAR)-mediated adhesion of immature hematological cells.

PubMed ID: 23486467

DOI: 10.1074/jbc.m112.442491

PubMed ID: 15861141

Title: Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide.

PubMed ID: 15861141

DOI: 10.1038/sj.emboj.7600635

PubMed ID: 16456079

Title: Structure of human urokinase plasminogen activator in complex with its receptor.

PubMed ID: 16456079

DOI: 10.1126/science.1121143

PubMed ID: 22285761

Title: Crystal structure of the urokinase receptor in a ligand-free form.

PubMed ID: 22285761

DOI: 10.1016/j.jmb.2011.12.058

Sequence Information:

  • Length: 335
  • Mass: 36978
  • Checksum: AB1963EA3DC77171
  • Sequence:
    • MGHPPLLPLL LLLHTCVPAS WGLRCMQCKT NGDCRVEECA LGQDLCRTTI VRLWEEGEEL 
ELVEKSCTHS EKTNRTLSYR TGLKITSLTE VVCGLDLCNQ GNSGRAVTYS RSRYLECISC 
GSSDMSCERG RHQSLQCRSP EEQCLDVVTH WIQEGEEGRP KDDRHLRGCG YLPGCPGSNG 
FHNNDTFHFL KCCNTTKCNE GPILELENLP QNGRQCYSCK GNSTHGCSSE ETFLIDCRGP 
MNQCLVATGT HEPKNQSYMV RGCATASMCQ HAHLGDAFSM NHIDVSCCTK SGCNHPDLDV 
QYRSGAAPQP GPAHLSLTIT LLMTARLWGG TLLWT

Genular Protein ID: 40423266

Symbol: M0R1I2_HUMAN

Name: N/A

UniProtKB Accession Codes:

M0R1I2

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 286
  • Mass: 31638
  • Checksum: 76AB999111869226
  • Sequence:
    • MGHPPLLPLL LLLHTCVPAS WGLRCMQCKT NGDCRVEECA LGQDLCRTTI VRLWEEGEEL 
ELVEKSCTHS EKTNRTLSYR TGLKITSLTE VVCGLDLCNQ GNSGRAVTYS RSRYLECISC 
GSSDMSCERG RHQSLQCRSP EEQCLDVVTH WIQEGEEGRP KDDRHLRGCG YLPGCPGSNG 
FHNNDTFHFL KCCNTTKCNE GPKPKNQSYM VRGCATASMC QHAHLGDAFS MNHIDVSCCT 
KSGCNHPDLD VQYRSGAAPQ PGPAHLSLTI TLLMTARLWG GTLLWT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.