Details for: POLR2B

Gene ID: 5431

Symbol: POLR2B

Ensembl ID: ENSG00000047315

Description: RNA polymerase II subunit B

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 1.47
    Marker Score: 514
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.45
    Marker Score: 166245
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.41
    Marker Score: 3085
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.32
    Marker Score: 1391
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.31
    Marker Score: 80607
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.3
    Marker Score: 562
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.28
    Marker Score: 622
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 1.28
    Marker Score: 514
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.27
    Marker Score: 10948
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.27
    Marker Score: 1434
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.26
    Marker Score: 1628
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.26
    Marker Score: 1387
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.25
    Marker Score: 43379
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.25
    Marker Score: 10877
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.25
    Marker Score: 297.5
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 1.24
    Marker Score: 507
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.24
    Marker Score: 11753
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 1.23
    Marker Score: 582.5
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.23
    Marker Score: 4745
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.23
    Marker Score: 497
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.23
    Marker Score: 1274
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.22
    Marker Score: 849
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.21
    Marker Score: 41323
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.21
    Marker Score: 826
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.21
    Marker Score: 1216
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.21
    Marker Score: 4150
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.21
    Marker Score: 12461
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.2
    Marker Score: 871
  • Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
    Fold Change: 1.19
    Marker Score: 391
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 1.19
    Marker Score: 3223.5
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.18
    Marker Score: 1692
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.18
    Marker Score: 1816
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.18
    Marker Score: 44626
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.17
    Marker Score: 17477.5
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 1.17
    Marker Score: 1150
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.16
    Marker Score: 368
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 1.16
    Marker Score: 254
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.16
    Marker Score: 1708
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 1.14
    Marker Score: 1100
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.14
    Marker Score: 4624
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.14
    Marker Score: 11241.5
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.13
    Marker Score: 4441
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.13
    Marker Score: 11430
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.13
    Marker Score: 1216
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.13
    Marker Score: 4713
  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.12
    Marker Score: 1194
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.12
    Marker Score: 41277.5
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.12
    Marker Score: 1180
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.11
    Marker Score: 1396.5
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.11
    Marker Score: 760
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 1.11
    Marker Score: 3069
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.11
    Marker Score: 1018
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 1.1
    Marker Score: 325
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.1
    Marker Score: 318
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 1.1
    Marker Score: 382
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.1
    Marker Score: 1370
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 1.1
    Marker Score: 379
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.09
    Marker Score: 1325
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.09
    Marker Score: 1455
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.09
    Marker Score: 10285.5
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.09
    Marker Score: 969
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 1.09
    Marker Score: 679.5
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 1.09
    Marker Score: 2269.5
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.09
    Marker Score: 8324
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 1.09
    Marker Score: 852
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 1.08
    Marker Score: 313
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.08
    Marker Score: 1574
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.08
    Marker Score: 315
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.08
    Marker Score: 451
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.08
    Marker Score: 3984.5
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 1.07
    Marker Score: 2041
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.07
    Marker Score: 1441
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.07
    Marker Score: 396
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 1.07
    Marker Score: 644
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.07
    Marker Score: 713
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 1.07
    Marker Score: 1197
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 1.07
    Marker Score: 1159
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: 1.07
    Marker Score: 1280
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 1.06
    Marker Score: 805
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.06
    Marker Score: 2160
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.06
    Marker Score: 3145
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.06
    Marker Score: 12283
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 1.05
    Marker Score: 480
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 1.05
    Marker Score: 2947
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.05
    Marker Score: 711
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.05
    Marker Score: 11799
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: 1.05
    Marker Score: 704
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.04
    Marker Score: 9158
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 1.04
    Marker Score: 1769
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.04
    Marker Score: 256.5
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.03
    Marker Score: 1115
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.03
    Marker Score: 2771
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.03
    Marker Score: 20560.5
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 1.03
    Marker Score: 504
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 1.03
    Marker Score: 1032
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.03
    Marker Score: 5047
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 1.02
    Marker Score: 1410
  • Cell Name: vasa recta descending limb cell (CL1001285)
    Fold Change: 1.02
    Marker Score: 280.5
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.02
    Marker Score: 1195.5
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 1.02
    Marker Score: 227.5

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Other Information

**Key Characteristics:** 1. **Subunit of RNAP II:** POLR2B is a conserved subunit of the RNAP II complex, which is composed of five subunits (RPB1, RPB2, RPB3, RPB4, and RPB5). 2. **Transcriptional Regulation:** POLR2B is involved in the regulation of gene expression, including transcription initiation, elongation, and termination. 3. **Viral Infections:** POLR2B plays a critical role in the transcription of viral genomes, particularly in the context of HIV-1 and influenza viruses. 4. **Immune Response:** POLR2B is significantly expressed in immune cells, suggesting its involvement in regulating immune responses and gene expression in these cells. **Pathways and Functions:** 1. **Transcriptional Regulation:** POLR2B is involved in the regulation of gene expression through the recruitment of transcription factors, RNA polymerase II, and other transcriptional regulators. 2. **Viral Transcription:** POLR2B is essential for the transcription of viral genomes, including HIV-1 and influenza viruses. 3. **Immune Response:** POLR2B is involved in regulating immune responses, including the transcription of genes involved in inflammation, immune cell development, and cytokine production. 4. **Telomere Maintenance:** POLR2B is involved in the maintenance of telomeres, which are essential for the stability of chromosomes. **Clinical Significance:** 1. **HIV-1 Infection:** POLR2B is a critical component of the HIV-1 transcription complex, and its dysregulation can lead to impaired transcriptional regulation and viral replication. 2. **Cancer:** POLR2B is overexpressed in various types of cancer, suggesting its potential role in tumorigenesis and cancer progression. 3. **Autoimmune Diseases:** POLR2B is involved in the regulation of immune responses, and its dysregulation can contribute to autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 4. **Neurological Disorders:** POLR2B is expressed in neural cells, and its dysregulation has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, POLR2B is a critical component of the RNAP II complex, playing a pivotal role in regulating gene expression, particularly in the context of immune response and viral infections. Its dysregulation can contribute to various diseases, highlighting the importance of understanding its function and regulation.

Genular Protein ID: 354198557

Symbol: RPB2_HUMAN

Name: DNA-directed RNA polymerase II subunit RPB2

UniProtKB Accession Codes:

P30876 A8K1A8 Q8IZ61

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 8 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 5 EMDB 10 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 11 Gene3D 6 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 12 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 7 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 41 RefSeq 3 Rhea 3 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1518060

Title: Primary structure of the second largest subunit of human RNA polymerase II (or B).

PubMed ID: 1518060

DOI: 10.1016/0022-2836(92)91071-v

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9110174

Title: Large-scale concatenation cDNA sequencing.

PubMed ID: 9110174

DOI: 10.1101/gr.7.4.353

PubMed ID: 9852112

Title: Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

PubMed ID: 9852112

DOI: 10.1074/jbc.273.51.34444

PubMed ID: 14992727

Title: Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus.

PubMed ID: 14992727

DOI: 10.1016/s1097-2765(04)00081-4

PubMed ID: 17998332

Title: Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes.

PubMed ID: 17998332

DOI: 10.1128/mcb.01356-07

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

  • Length: 1174
  • Mass: 133897
  • Checksum: 32BEDF7F95E4DE10
  • Sequence:
    • MYDADEDMQY DEDDDEITPD LWQEACWIVI SSYFDEKGLV RQQLDSFDEF IQMSVQRIVE 
DAPPIDLQAE AQHASGEVEE PPRYLLKFEQ IYLSKPTHWE RDGAPSPMMP NEARLRNLTY 
SAPLYVDITK TVIKEGEEQL QTQHQKTFIG KIPIMLRSTY CLLNGLTDRD LCELNECPLD 
PGGYFIINGS EKVLIAQEKM ATNTVYVFAK KDSKYAYTGE CRSCLENSSR PTSTIWVSML 
ARGGQGAKKS AIGQRIVATL PYIKQEVPII IVFRALGFVS DRDILEHIIY DFEDPEMMEM 
VKPSLDEAFV IQEQNVALNF IGSRGAKPGV TKEKRIKYAK EVLQKEMLPH VGVSDFCETK 
KAYFLGYMVH RLLLAALGRR ELDDRDHYGN KRLDLAGPLL AFLFRGMFKN LLKEVRIYAQ 
KFIDRGKDFN LELAIKTRII SDGLKYSLAT GNWGDQKKAH QARAGVSQVL NRLTFASTLS 
HLRRLNSPIG RDGKLAKPRQ LHNTLWGMVC PAETPEGHAV GLVKNLALMA YISVGSQPSP 
ILEFLEEWSM ENLEEISPAA IADATKIFVN GCWVGIHKDP EQLMNTLRKL RRQMDIIVSE 
VSMIRDIRER EIRIYTDAGR ICRPLLIVEK QKLLLKKRHI DQLKEREYNN YSWQDLVASG 
VVEYIDTLEE ETVMLAMTPD DLQEKEVAYC STYTHCEIHP SMILGVCASI IPFPDHNQSP 
RNTYQSAMGK QAMGVYITNF HVRMDTLAHV LYYPQKPLVT TRSMEYLRFR ELPAGINSIV 
AIASYTGYNQ EDSVIMNRSA VDRGFFRSVF YRSYKEQESK KGFDQEEVFE KPTRETCQGM 
RHAIYDKLDD DGLIAPGVRV SGDDVIIGKT VTLPENEDEL ESTNRRYTKR DCSTFLRTSE 
TGIVDQVMVT LNQEGYKFCK IRVRSVRIPQ IGDKFASRHG QKGTCGIQYR QEDMPFTCEG 
ITPDIIINPH AIPSRMTIGH LIECLQGKVS ANKGEIGDAT PFNDAVNVQK ISNLLSDYGY 
HLRGNEVLYN GFTGRKITSQ IFIGPTYYQR LKHMVDDKIH SRARGPIQIL NRQPMEGRSR 
DGGLRFGEME RDCQIAHGAA QFLRERLFEA SDPYQVHVCN LCGIMAIANT RTHTYECRGC 
RNKTQISLVR MPYACKLLFQ ELMSMSIAPR MMSV

Genular Protein ID: 1853661889

Symbol: B4DHJ3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DHJ3

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 3 DNASU 1 EC 1 EMBL 2 GO 6 Gene3D 6 GenomeRNAi 1 InterPro 12 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 14 RefSeq 1 Rhea 3 RuleBase 2 SUPFAM 1

Sequence Information:

  • Length: 1167
  • Mass: 133027
  • Checksum: 79754AB8ABB17D0B
  • Sequence:
    • MQYDEDDDEI TPDLWQEACW IVISSYFDEK GLVRQQLDSF DEFIQMSVQR IVEDAPPIDL 
QAEAQHASGE VEEPPRYLLK FEQIYLSKPT HRERDGAPSP MMPNEARLRN LTYSAPLYVD 
ITKTVIKEGE EQLQTQHQKT FIGKIPIMLR STYCLLNGLT DRDLCELNEC PLDPGGYFII 
NGSEKVLIAQ EKMATNTVYV FAKKDSKYAY TGECRSCLEN SSRPTSTIWV SMLARGGQGA 
KKSAIGQRIV ATLPYIKQEV PIIIVFRALG FVSDRDILEH IIYDFEDPEM MEMVKPSLDE 
AFVIQEQNVA LNFIGSRGAK PGVTKEKRIK YAKEVLQKEM LPHVGVSDFC ETKKAYFLGY 
MVHRLLLAAL GRRELDDRDH YGNKRLDLAG PLLAFLFRGM FKNLLKEVRI YAQKFIDRGK 
DFNLELAIKT RIISDGLKYS LATGNWGDQK KAHQARAGVS QVLNRLTFAS TLSHLRRLNS 
PIGRDGKLAK PRQLHNTLWG MVCPAETPEG HAVGLVKNLA LMAYISVGSQ PSPILEFLEE 
WSMENLEEIS PAAIADATKI FVNGCWVGIH KDPEQLMNTL RKLRRQMDII VSEVSMIRDI 
REREIRIYTD AGRICRPLLI VEKQKLLLKK RHIDQLKERE YNNYSWQDLV ASGVVEYIDT 
LEEETVMLAM TPDDLQEKEV AYCSTYTHCE IHPSMILGVC ASIIPFPDHN QSPRNTYQSA 
MGKQAMGVYI TNFHVRMDTL AHVLYYPQKP LVTTRSMEYL RFRELPAGIN SIVAIASYTG 
YNQEDSVIMN RSAVDRGFFR SVFYRSYKEQ ESKKGFDQEE VFEKPTRETC QGMRHAIYDK 
LDDDGLIAPG VRVSGDDVII GKTVTLPENE DELESTNRRY TKRDCSTFLR TSETGIVDQV 
MVTLNQEGYK FCKIRVRSVR IPQIGDKFAS RHGQKGTCGI QYRQEDMPFT CEGITPDIII 
NPHAIPSRMT IGHLIECLQG KVSANKGEIG DATPFNDAVN VQKISNLLSD YGYHLRGNEV 
LYNGFTGRKI TSQIFIGPTY YQRLKHMVDD KIHSRARGPI QILNRQPMEG RSRDGGLRFG 
EMERDCQIAH GAAQFLRERL FEASDPYQVH VCNLCGIMAI ANTRTHTYEC RGCRNKTQIS 
LVRMPYACKL LFQELMSMSI APRMMSV

Genular Protein ID: 1590192009

Symbol: B4DH29_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DH29

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 3 DNASU 1 EC 1 EMBL 2 GO 6 Gene3D 6 GenomeRNAi 1 InterPro 12 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 14 RefSeq 3 Rhea 3 RuleBase 2 SUPFAM 1

Sequence Information:

  • Length: 1099
  • Mass: 125219
  • Checksum: D610267D44614F74
  • Sequence:
    • MLDCNQPRYL LKFEQIYLSK PTHWERDGAP SPMMPNEARL RNLTYSAPLY VDITKTVIKE 
GEEQLQTQHQ KTFIGKIPIM LRSTYCLLNG LTDRDLCELN ECPLDPGGYF IINGSEKVLI 
AQEKMATNTV YVFAKKDSKY AYTGECRSCL ENSSRPTSTI WVSMLARGGQ GAKKSAIGQR 
IVATLPYIKQ EVPIIIVFRA LGFVSDRDIL EHIIYDFEDP EMMEMVKPSL DEAFVIQEQN 
VALNFIGSRG AKPGVTKEKR IKYAKEVLQK EMLPHVGVSD FCETKKAYFL GYMVHRLLLA 
ALGRRELDDR DHYGNKRLDL AGPLLAFLFR GMFKNLLKEV RIYAQKFIDR GKDFNLELAI 
KTRIISDGLK YSLATGNWGD QKKAHQARAG VSQVLNRLTF ASTLSHLRRL NSPIGRDGKL 
AKPRQLHNTL WGMVCPAETP EGHAVGLVKN LALMAYISVG SQPSPILEFL EEWSMENLEE 
ISPAAIADAT KIFVNGCWVG IHKDPEQLMN TLRKLRRQMD IIVSEVSMIR DIREREIRIY 
TDAGRICRPL LIVEKQKLLL KKRHIDQLKE REYNNYSWQD LVASGVVEYI DTLEEETVML 
AMTPDDLQEK EVAYCSTYTH CEIHPSMILG VCASIIPFPD HNQSPRNTYQ SAMGKQAMGV 
YITNFHVRMD TLAHVLYYPQ KPLVTTRSME YLRFRELPAG INSIVAIASY TGYNQEDSVI 
MNRSAVDRSF FRSVFYRSYK EQESKKGFDQ EEVFEKPTRE TCQGMRHAIY DKLDDDGLIA 
PGVRVSGDDV IIGKTVTLPE NEDELESTNR RYTKRDCSTF LRTSETGIVD QVMVTLNQEG 
YKFCKIRVRS VRIPQIGDKF ASRHGQKGTC GIQYRQEDMP FTCEGITPDI IINPHAIPSR 
MTIGHLIECL QGKVSANKGE IGDATPFNDA VNVQKISNLL SDYGYHLRGN EVLYNGFTGR 
KITSQIFIGP TYYQRLKHMV DDKIHSRARG PIQILNRQPM EGRSRDGGLR FGEMERDCQI 
AHGAAQFLRE RLFEASDPYQ VHVCNLCGIM AIANTRTHTY ECRGCRNKTQ ISLVRMPYAC 
KLLFQELMSM SIAPRMMSV

Genular Protein ID: 1469814631

Symbol: C9J2Y9_HUMAN

Name: N/A

UniProtKB Accession Codes:

C9J2Y9

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 3 ChiTaRS 1 DNASU 1 EC 1 EMBL 1 EPD 2 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 6 GeneTree 1 GenomeRNAi 1 HGNC 1 IntAct 1 InterPro 12 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 14 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 3 RuleBase 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

Sequence Information:

  • Length: 1167
  • Mass: 133057
  • Checksum: DD600BBDDA6BCD0A
  • Sequence:
    • MQYDEDDDEI TPDLWQEACW IVISSYFDEK GLVRQQLDSF DEFIQMSVQR IVEDAPPIDL 
QAEAQHASGE VEEPPRYLLK FEQIYLSKPT HWERDGAPSP MMPNEARLRN LTYSAPLYVD 
ITKTVIKEGE EQLQTQHQKT FIGKIPIMLR STYCLLNGLT DRDLCELNEC PLDPGGYFII 
NGSEKVLIAQ EKMATNTVYV FAKKDSKYAY TGECRSCLEN SSRPTSTIWV SMLARGGQGA 
KKSAIGQRIV ATLPYIKQEV PIIIVFRALG FVSDRDILEH IIYDFEDPEM MEMVKPSLDE 
AFVIQEQNVA LNFIGSRGAK PGVTKEKRIK YAKEVLQKEM LPHVGVSDFC ETKKAYFLGY 
MVHRLLLAAL GRRELDDRDH YGNKRLDLAG PLLAFLFRGM FKNLLKEVRI YAQKFIDRGK 
DFNLELAIKT RIISDGLKYS LATGNWGDQK KAHQARAGVS QVLNRLTFAS TLSHLRRLNS 
PIGRDGKLAK PRQLHNTLWG MVCPAETPEG HAVGLVKNLA LMAYISVGSQ PSPILEFLEE 
WSMENLEEIS PAAIADATKI FVNGCWVGIH KDPEQLMNTL RKLRRQMDII VSEVSMIRDI 
REREIRIYTD AGRICRPLLI VEKQKLLLKK RHIDQLKERE YNNYSWQDLV ASGVVEYIDT 
LEEETVMLAM TPDDLQEKEV AYCSTYTHCE IHPSMILGVC ASIIPFPDHN QSPRNTYQSA 
MGKQAMGVYI TNFHVRMDTL AHVLYYPQKP LVTTRSMEYL RFRELPAGIN SIVAIASYTG 
YNQEDSVIMN RSAVDRGFFR SVFYRSYKEQ ESKKGFDQEE VFEKPTRETC QGMRHAIYDK 
LDDDGLIAPG VRVSGDDVII GKTVTLPENE DELESTNRRY TKRDCSTFLR TSETGIVDQV 
MVTLNQEGYK FCKIRVRSVR IPQIGDKFAS RHGQKGTCGI QYRQEDMPFT CEGITPDIII 
NPHAIPSRMT IGHLIECLQG KVSANKGEIG DATPFNDAVN VQKISNLLSD YGYHLRGNEV 
LYNGFTGRKI TSQIFIGPTY YQRLKHMVDD KIHSRARGPI QILNRQPMEG RSRDGGLRFG 
EMERDCQIAH GAAQFLRERL FEASDPYQVH VCNLCGIMAI ANTRTHTYEC RGCRNKTQIS 
LVRMPYACKL LFQELMSMSI APRMMSV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.