Details for: PPP1R8

Gene ID: 5511

Symbol: PPP1R8

Ensembl ID: ENSG00000117751

Description: protein phosphatase 1 regulatory subunit 8

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 100.4852
    Cell Significance Index: -15.6300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 66.2742
    Cell Significance Index: -16.8100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 46.6934
    Cell Significance Index: -22.0500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 44.7254
    Cell Significance Index: -18.1700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 41.4864
    Cell Significance Index: -21.3400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 19.1622
    Cell Significance Index: -18.3000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 16.3023
    Cell Significance Index: -20.1000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.6260
    Cell Significance Index: -17.7500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.3877
    Cell Significance Index: -21.2600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.5744
    Cell Significance Index: -14.0500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.3492
    Cell Significance Index: -7.3300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.5548
    Cell Significance Index: 153.8100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1860
    Cell Significance Index: 1070.8400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9811
    Cell Significance Index: 106.7200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8178
    Cell Significance Index: 133.0100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.7694
    Cell Significance Index: 40.0800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.6870
    Cell Significance Index: 43.3000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.5801
    Cell Significance Index: 15.7900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.5545
    Cell Significance Index: 19.2700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4991
    Cell Significance Index: 34.5200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4268
    Cell Significance Index: 85.6200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.3922
    Cell Significance Index: 8.2100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3571
    Cell Significance Index: 67.9500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.3429
    Cell Significance Index: 18.0100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3287
    Cell Significance Index: 65.2300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3087
    Cell Significance Index: 168.5700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2926
    Cell Significance Index: 6.3400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2925
    Cell Significance Index: 129.3300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.2753
    Cell Significance Index: 7.3500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2734
    Cell Significance Index: 37.5400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.2657
    Cell Significance Index: 3.6300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.2272
    Cell Significance Index: 2.4700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2269
    Cell Significance Index: 40.9000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2138
    Cell Significance Index: 27.4100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.2134
    Cell Significance Index: 15.0900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1938
    Cell Significance Index: 69.5100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1911
    Cell Significance Index: 8.9100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1846
    Cell Significance Index: 13.7600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1756
    Cell Significance Index: 22.6800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1653
    Cell Significance Index: 20.3200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1604
    Cell Significance Index: 4.0100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1552
    Cell Significance Index: 8.0600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1286
    Cell Significance Index: 3.6000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1255
    Cell Significance Index: 7.0400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1218
    Cell Significance Index: 84.2200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1169
    Cell Significance Index: 13.7900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1161
    Cell Significance Index: 3.1100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0677
    Cell Significance Index: 1.9500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0498
    Cell Significance Index: 1.3100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0209
    Cell Significance Index: 0.9800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0161
    Cell Significance Index: 0.2700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0134
    Cell Significance Index: 0.4700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0025
    Cell Significance Index: 0.2000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0013
    Cell Significance Index: 0.0900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0024
    Cell Significance Index: -4.6000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0077
    Cell Significance Index: -5.8500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0107
    Cell Significance Index: -1.8200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0111
    Cell Significance Index: -20.4900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0115
    Cell Significance Index: -7.3100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0131
    Cell Significance Index: -20.1300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0138
    Cell Significance Index: -18.8300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0154
    Cell Significance Index: -11.3200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0181
    Cell Significance Index: -0.8200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0186
    Cell Significance Index: -13.7500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0238
    Cell Significance Index: -10.8000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0249
    Cell Significance Index: -0.5300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0319
    Cell Significance Index: -18.0100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0385
    Cell Significance Index: -24.0500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0424
    Cell Significance Index: -4.3300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0560
    Cell Significance Index: -1.4300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0583
    Cell Significance Index: -3.9200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0621
    Cell Significance Index: -17.8700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0638
    Cell Significance Index: -0.7600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0678
    Cell Significance Index: -7.9000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0890
    Cell Significance Index: -12.9300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0957
    Cell Significance Index: -1.6400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0962
    Cell Significance Index: -11.0200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0979
    Cell Significance Index: -6.0200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1110
    Cell Significance Index: -23.3700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1410
    Cell Significance Index: -6.2400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1467
    Cell Significance Index: -4.7000
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.1515
    Cell Significance Index: -1.2100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1677
    Cell Significance Index: -6.3500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1918
    Cell Significance Index: -4.2000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1980
    Cell Significance Index: -20.6200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2169
    Cell Significance Index: -17.1800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2287
    Cell Significance Index: -1.8700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.2389
    Cell Significance Index: -3.5800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2445
    Cell Significance Index: -14.9900
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.2508
    Cell Significance Index: -3.5200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.3107
    Cell Significance Index: -3.5300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.3133
    Cell Significance Index: -9.2000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3348
    Cell Significance Index: -8.9600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3445
    Cell Significance Index: -9.8300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3560
    Cell Significance Index: -9.1500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3853
    Cell Significance Index: -7.5200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3953
    Cell Significance Index: -12.5900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4006
    Cell Significance Index: -11.8000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4023
    Cell Significance Index: -4.1700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4190
    Cell Significance Index: -12.0100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PPP1R8 is a highly conserved protein that belongs to the PP1R family, which consists of four subunits (PP1R1-PP1R4). The PPP1R8 subunit is specifically localized to the nucleus, where it inhibits the activity of PP1, thereby regulating its dephosphorylation activity. This regulatory mechanism is crucial for maintaining proper cellular homeostasis and preventing aberrant protein phosphorylation events. **Pathways and Functions:** The PPP1R8 subunit is involved in various cellular processes, including: 1. **Cell population proliferation**: PPP1R8 regulates the cell cycle progression by modulating the activity of PP1, which in turn affects the phosphorylation status of key cell cycle regulators. 2. **DNA binding and endonuclease activity**: PPP1R8 interacts with DNA-binding proteins and modulates their activity, influencing DNA replication and repair processes. 3. **Metabolism of RNA**: PPP1R8 regulates the processing and splicing of RNA molecules, including pre-mRNA and mRNA, by modulating the activity of RNA-binding proteins. 4. **Protein binding and regulation**: PPP1R8 interacts with various proteins, including transcription factors and chromatin-modifying enzymes, to regulate their activity and impact cellular processes. **Clinical Significance:** The dysregulation of PPP1R8 has been implicated in various diseases, including: 1. **Neurological disorders**: Mutations in PPP1R8 have been associated with neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 2. **Cancer**: Altered expression of PPP1R8 has been observed in various types of cancer, including breast cancer and colon cancer. 3. **Metabolic disorders**: PPP1R8 has been implicated in the regulation of metabolic processes, including glucose metabolism and lipid synthesis, which has implications for the diagnosis and treatment of metabolic disorders. **Significantly Expressed Cells:** PPP1R8 is highly expressed in various cell types, including: 1. **Mural cells**: PPP1R8 is expressed in mural cells, which play a crucial role in maintaining the integrity of blood vessels. 2. **Pancreatic acinar cells**: PPP1R8 is expressed in pancreatic acinar cells, which are involved in the regulation of insulin secretion. 3. **Placental villous trophoblasts**: PPP1R8 is expressed in placental villous trophoblasts, which are involved in the regulation of fetal development. 4. **Erythroid progenitor cells**: PPP1R8 is expressed in erythroid progenitor cells, which are involved in the regulation of erythropoiesis. In conclusion, PPP1R8 is a critical regulator of cellular processes, and its dysregulation has been implicated in various diseases. Further research is needed to fully elucidate the mechanisms by which PPP1R8 regulates cellular processes and to explore its therapeutic potential in diseases associated with its dysregulation.

Genular Protein ID: 2483283387

Symbol: PP1R8_HUMAN

Name: Nuclear inhibitor of protein phosphatase 1

UniProtKB Accession Codes:

Q12972 Q5TEJ2 Q5TEJ4 Q5TIF2 Q6PKF6 Q9UBH1 Q9UBZ0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EC 1 ELM 1 EMBL 22 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7524097

Title: ard-1: a human gene that reverses the effects of temperature-sensitive and deletion mutations in the Escherichia coli rne gene and encodes an activity producing RNase E-like cleavages.

PubMed ID: 7524097

DOI: 10.1073/pnas.91.22.10591

PubMed ID: 10103062

Title: Organization and alternate splice products of the gene encoding nuclear inhibitor of protein phosphatase-1 (NIPP-1).

PubMed ID: 10103062

DOI: 10.1046/j.1432-1327.1999.00272.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7499293

Title: Molecular cloning of NIPP-1, a nuclear inhibitor of protein phosphatase-1, reveals homology with polypeptides involved in RNA processing.

PubMed ID: 7499293

DOI: 10.1074/jbc.270.47.28068

PubMed ID: 9153239

Title: ARD-1 cDNA from human cells encodes a site-specific single-strand endoribonuclease that functionally resembles Escherichia coli RNase E.

PubMed ID: 9153239

DOI: 10.1074/jbc.272.21.13823

PubMed ID: 10432294

Title: Mapping of the RNA-binding and endoribonuclease domains of NIPP1, a nuclear targeting subunit of protein phosphatase 1.

PubMed ID: 10432294

DOI: 10.1042/bj3420013

PubMed ID: 10564811

Title: Alternative splicing regulates the production of ARD-1 endoribonuclease and NIPP-1, an inhibitor of protein phosphatase-1, as isoforms encoded by the same gene.

PubMed ID: 10564811

DOI: 10.1016/s0378-1119(99)00435-7

PubMed ID: 11104670

Title: The C-terminus of NIPP1 (nuclear inhibitor of protein phosphatase-1) contains a novel binding site for protein phosphatase-1 that is controlled by tyrosine phosphorylation and RNA binding.

PubMed ID: 11104670

DOI: 10.1042/bj3520651

PubMed ID: 10827081

Title: NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a regulator of pre-mRNA splicing and mitotic entry.

PubMed ID: 10827081

DOI: 10.1074/jbc.m001676200

PubMed ID: 11034904

Title: Nuclear and subnuclear targeting sequences of the protein phosphatase-1 regulator NIPP1.

PubMed ID: 11034904

DOI: 10.1242/jcs.113.21.3761

PubMed ID: 11739654

Title: Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells.

PubMed ID: 11739654

DOI: 10.1242/jcs.114.23.4219

PubMed ID: 11909864

Title: The protein phosphatase-1 regulator NIPP1 is also a splicing factor involved in a late step of spliceosome assembly.

PubMed ID: 11909864

DOI: 10.1074/jbc.m200847200

PubMed ID: 12105215

Title: Phosphorylation-dependent interaction between the splicing factors SAP155 and NIPP1.

PubMed ID: 12105215

DOI: 10.1074/jbc.m204427200

PubMed ID: 12788942

Title: The protein phosphatase-1 (PP1) regulator, nuclear inhibitor of PP1 (NIPP1), interacts with the polycomb group protein, embryonic ectoderm development (EED), and functions as a transcriptional repressor.

PubMed ID: 12788942

DOI: 10.1074/jbc.m302273200

PubMed ID: 14699119

Title: Inhibition of spliceosome assembly by the cell cycle-regulated protein kinase MELK and involvement of splicing factor NIPP1.

PubMed ID: 14699119

DOI: 10.1074/jbc.m311466200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20516061

Title: Identification and characterization of a novel human PP1 phosphatase complex.

PubMed ID: 20516061

DOI: 10.1074/jbc.m110.109801

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

Sequence Information:

  • Length: 351
  • Mass: 38479
  • Checksum: 0A0E92B033E37641
  • Sequence:
    • MAAAANSGSS LPLFDCPTWA GKPPPGLHLD VVKGDKLIEK LIIDEKKYYL FGRNPDLCDF 
TIDHQSCSRV HAALVYHKHL KRVFLIDLNS THGTFLGHIR LEPHKPQQIP IDSTVSFGAS 
TRAYTLREKP QTLPSAVKGD EKMGGEDDEL KGLLGLPEEE TELDNLTEFN TAHNKRISTL 
TIEEGNLDIQ RPKRKRKNSR VTFSEDDEII NPEDVDPSVG RFRNMVQTAV VPVKKKRVEG 
PGSLGLEESG SRRMQNFAFS GGLYGGLPPT HSEAGSQPHG IHGTALIGGL PMPYPNLAPD 
VDLTPVVPSA VNMNPAPNPA VYNPEAVNEP KKKKYAKEAW PGKKPTPSLL I

Genular Protein ID: 3575036413

Symbol: Q6ICT4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6ICT4

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 8 ExpressionAtlas 1 GO 2 HOGENOM 1 NCBI Taxonomy 1 OrthoDB 1 PharmGKB 1 RefSeq 2 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 127
  • Mass: 13344
  • Checksum: D29E123EA36C9F94
  • Sequence:
    • MVQTAVVPVK KKRVEGPGSL GLEESGSRRM QNFAFSGGLY GGLPPTHSEA GSQPHGIHGT 
ALIGGLPMPY PNLAPDVDLT PVVPSAVNMN PAPNPAVYNP EAVNEPKKKK YAKEAWPGKK 
PTPSLLI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.