Details for: PRCC
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 181.8121
Cell Significance Index: -28.2800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 101.4416
Cell Significance Index: -25.7300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 68.0727
Cell Significance Index: -27.6600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 61.6075
Cell Significance Index: -31.6900 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 48.2771
Cell Significance Index: -32.4000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 29.1597
Cell Significance Index: -27.8400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 25.2483
Cell Significance Index: -31.1300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 9.7775
Cell Significance Index: -26.1900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.1030
Cell Significance Index: -31.9800 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 8.0874
Cell Significance Index: -24.8400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 5.9810
Cell Significance Index: -13.0900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 1.7563
Cell Significance Index: 204.6800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.6469
Cell Significance Index: 1487.0300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.2237
Cell Significance Index: 133.1000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.1956
Cell Significance Index: 71.7800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.8483
Cell Significance Index: 22.6500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.8035
Cell Significance Index: 159.4600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.7597
Cell Significance Index: 152.3900 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.6937
Cell Significance Index: 18.2400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.6541
Cell Significance Index: 22.7300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.6382
Cell Significance Index: 17.3700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6137
Cell Significance Index: 60.7100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5358
Cell Significance Index: 65.8800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.5108
Cell Significance Index: 92.0900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.5053
Cell Significance Index: 26.2500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.5035
Cell Significance Index: 10.5400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4897
Cell Significance Index: 14.1100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.4828
Cell Significance Index: 56.9400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4629
Cell Significance Index: 21.7600 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.4419
Cell Significance Index: 57.0900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4097
Cell Significance Index: 223.7300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.3945
Cell Significance Index: 54.1800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.3873
Cell Significance Index: 24.4100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.3781
Cell Significance Index: 19.8500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.3697
Cell Significance Index: 132.6000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3637
Cell Significance Index: 7.8800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3564
Cell Significance Index: 24.6500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3170
Cell Significance Index: 8.8600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3115
Cell Significance Index: 137.7100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2575
Cell Significance Index: 33.0100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.2547
Cell Significance Index: 18.9800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.2473
Cell Significance Index: 11.5300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.2427
Cell Significance Index: 15.6600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.2248
Cell Significance Index: 11.7100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2056
Cell Significance Index: 39.1300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1946
Cell Significance Index: 134.5800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1932
Cell Significance Index: 14.8300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1626
Cell Significance Index: 7.3700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1009
Cell Significance Index: 5.6600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0590
Cell Significance Index: 4.1700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.0545
Cell Significance Index: 1.4000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0374
Cell Significance Index: 70.5100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0097
Cell Significance Index: 0.3100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0082
Cell Significance Index: 15.1000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0069
Cell Significance Index: 10.6500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0067
Cell Significance Index: 0.4100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0036
Cell Significance Index: 0.0600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0002
Cell Significance Index: 0.1100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0007
Cell Significance Index: -0.0200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0068
Cell Significance Index: -9.2800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0089
Cell Significance Index: -0.1900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0121
Cell Significance Index: -5.5100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0161
Cell Significance Index: -12.1700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0165
Cell Significance Index: -2.8200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0210
Cell Significance Index: -15.4200 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.0269
Cell Significance Index: -0.3400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0288
Cell Significance Index: -21.3000 - Cell Name: kidney cell (CL1000497)
Fold Change: -0.0338
Cell Significance Index: -0.2700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0368
Cell Significance Index: -3.7600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0516
Cell Significance Index: -29.0900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0531
Cell Significance Index: -0.9100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0559
Cell Significance Index: -34.9100 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0587
Cell Significance Index: -0.7000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0723
Cell Significance Index: -4.8600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.0797
Cell Significance Index: -2.3400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0859
Cell Significance Index: -24.7100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.1076
Cell Significance Index: -1.1700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1080
Cell Significance Index: -2.9000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1135
Cell Significance Index: -16.5000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1141
Cell Significance Index: -3.2700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1141
Cell Significance Index: -4.0100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1381
Cell Significance Index: -6.1100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1632
Cell Significance Index: -34.3700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1831
Cell Significance Index: -20.9800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2020
Cell Significance Index: -7.6500 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2140
Cell Significance Index: -2.9200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2161
Cell Significance Index: -5.5200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2725
Cell Significance Index: -28.3700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3449
Cell Significance Index: -27.3200 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.3632
Cell Significance Index: -3.3500 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.4787
Cell Significance Index: -14.1000 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.4911
Cell Significance Index: -7.4000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5227
Cell Significance Index: -32.0500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.5275
Cell Significance Index: -10.3000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.5425
Cell Significance Index: -13.5600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.5439
Cell Significance Index: -11.9100 - Cell Name: peg cell (CL4033014)
Fold Change: -0.5726
Cell Significance Index: -13.2300 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.5911
Cell Significance Index: -10.4500 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.6267
Cell Significance Index: -8.7900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.6283
Cell Significance Index: -17.9300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1914187420
Symbol: PRCC_HUMAN
Name: Proline-rich protein PRCC
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8872474
Title: The t(X;1)(p11.2;q21.2) translocation in papillary renal cell carcinoma fuses a novel gene PRCC to the TFE3 transcription factor gene.
PubMed ID: 8872474
DOI: 10.1093/hmg/5.9.1333
PubMed ID: 8986805
Title: Fusion of the transcription factor TFE3 gene to a novel gene, PRCC, in t(X;1)(p11;q21)-positive papillary renal cell carcinomas.
PubMed ID: 8986805
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11717438
Title: Impairment of MAD2B-PRCC interaction in mitotic checkpoint defective t(X;1)-positive renal cell carcinomas.
PubMed ID: 11717438
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 491
- Mass: 52418
- Checksum: F99CFD9D42725D57
- Sequence:
MSLVAYASSD ESEPDEAEPE PEEEEAVAPT SGPALGGLFA SLPAPKGPAL LPPPPQMLAP AFPPPLLLPP PTGDPRLQPP PPLPFGLGGF PPPPGVSPAE AAGVGEGLGL GLPSPRGPGL NLPPPIGGAG PPLGLPKPKK RKEPVKIAAP ELHKGDSDSE EDEPTKKKTI LQGSSEGTGL SALLPQPKNL TVKETNRLLL PHAFSRKPSD GSPDTKPSRL ASKTKTSSLA PVVGTTTTTP SPSAIKAAAK SAALQVTKQI TQEEDDSDEE VAPENFFSLP EKAEPPGVEP YPYPIPTVPE ELPPGTEPEP AFQDDAANAP LEFKMAAGSS GAPWMPKPGD DYSYNQFSTY GDANAAGAYY QDYYSGGYYP AQDPALVPPQ EIAPDASFID DEAFKRLQGK RNRGREEINF VEIKGDDQLS GAQQWMTKSL TEEKTMKSFS KKKGEQPTGQ QRRKHQITYL IHQAKERELE LKNTWSENKL SRRQTQAKYG F
Genular Protein ID: 3336304909
Symbol: Q96FT4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 491
- Mass: 52422
- Checksum: 4A808B462FC48126
- Sequence:
MSLVAYASSD ESEPDEAEPE PEEEEAVAPT SGPALGGLFA SLPAPKGPAL LPPPPQMLAP AFPPPLLLPP PTGDPRLQPP PPLPFGLGGF PPPPGVSPAE AAGVGEGLGL GLPSPRGPGL NLPPPIGGAG PPLGLPKPKK RKEPVKIAAP ELHKGDSDSE EDEPTKKKTI LQGSSEGTGL SALLPQPKNL TVKETNRLLL PHAFSRKPSD GSPDTKPSRL ASKTKTSSLA PVVGTTTTTP SPSAIKAAAK SAALQVTKQI TQEEDDSDEE VAPENFFSLP EKAEPPGVEP YPYPIPTVPE ELPPGTEPEP AFQDDAANAP LEFKMAAGSS GAPWMPKPGD DYSYNQFSTY GDANAAGAYY QDYYSGGYYP AQDPALVPTQ EIAPDASFID DEAFKRLQGK RNRGREEINF VEIKGDDQLS GAQQWMTKSL TEEKTMKSFS KKKGEQPTGQ QRRKHQITYL IHQAKERELE LKNTWSENKL SRRQTQAKYG F
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.