Details for: PRKCSH
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 272.5252
Cell Significance Index: -42.3900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 132.4695
Cell Significance Index: -33.6000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 107.7686
Cell Significance Index: -50.8800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 106.4351
Cell Significance Index: -43.2400 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 95.9981
Cell Significance Index: -49.3800 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 75.8395
Cell Significance Index: -50.8900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 45.4363
Cell Significance Index: -43.3800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 37.3493
Cell Significance Index: -46.0500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 15.9695
Cell Significance Index: -42.7800 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 12.6455
Cell Significance Index: -38.8400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 11.9512
Cell Significance Index: -47.1600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 5.1494
Cell Significance Index: -11.2700 - Cell Name: kidney cell (CL1000497)
Fold Change: 2.5156
Cell Significance Index: 20.0900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 2.0098
Cell Significance Index: 53.7600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.6444
Cell Significance Index: 225.8200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.5445
Cell Significance Index: 42.0400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.3160
Cell Significance Index: 718.7100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.2932
Cell Significance Index: 60.3000 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.2164
Cell Significance Index: 157.1500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 1.1588
Cell Significance Index: 14.8400 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 1.1499
Cell Significance Index: 24.0700 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.1485
Cell Significance Index: 30.2000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.1004
Cell Significance Index: 31.7100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.0688
Cell Significance Index: 55.6700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.0579
Cell Significance Index: 22.9200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.0561
Cell Significance Index: 47.8700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.0329
Cell Significance Index: 127.0000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.0271
Cell Significance Index: 185.1500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.9301
Cell Significance Index: 177.0100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.9160
Cell Significance Index: 68.2700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9139
Cell Significance Index: 148.6300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.8767
Cell Significance Index: 45.5400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.7490
Cell Significance Index: 20.0000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.6804
Cell Significance Index: 135.0200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.6662
Cell Significance Index: 85.4000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.6493
Cell Significance Index: 16.2300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.5858
Cell Significance Index: 37.8000 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.5566
Cell Significance Index: 111.6500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.5374
Cell Significance Index: 237.5900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.5036
Cell Significance Index: 454.7000 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.4958
Cell Significance Index: 5.3900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4770
Cell Significance Index: 47.1900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.4544
Cell Significance Index: 12.7000 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.4272
Cell Significance Index: 12.5500 - Cell Name: peg cell (CL4033014)
Fold Change: 0.3978
Cell Significance Index: 9.1900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.3553
Cell Significance Index: 25.1300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.3185
Cell Significance Index: 14.9700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2844
Cell Significance Index: 102.0100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.2193
Cell Significance Index: 4.6700 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.1954
Cell Significance Index: 2.2200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.1901
Cell Significance Index: 22.4200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.1887
Cell Significance Index: 5.0600 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.1859
Cell Significance Index: 3.2900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1714
Cell Significance Index: 118.5200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1013
Cell Significance Index: 3.5600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0928
Cell Significance Index: 15.8500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.0863
Cell Significance Index: 5.1800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0648
Cell Significance Index: 3.4000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0370
Cell Significance Index: 0.6200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0170
Cell Significance Index: 12.8500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0050
Cell Significance Index: 0.1600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0064
Cell Significance Index: -12.0200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0172
Cell Significance Index: -12.6300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0187
Cell Significance Index: -1.9100 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.0201
Cell Significance Index: -0.1800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0243
Cell Significance Index: -44.7800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0292
Cell Significance Index: -44.9200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0387
Cell Significance Index: -52.6200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0507
Cell Significance Index: -37.5400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0610
Cell Significance Index: -38.7600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0795
Cell Significance Index: -44.8500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0927
Cell Significance Index: -42.0700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0940
Cell Significance Index: -58.7300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1045
Cell Significance Index: -3.6300 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.1147
Cell Significance Index: -2.1200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1240
Cell Significance Index: -14.4500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1338
Cell Significance Index: -38.4900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1565
Cell Significance Index: -8.7800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1904
Cell Significance Index: -12.0000 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.2202
Cell Significance Index: -3.3000 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2509
Cell Significance Index: -6.4100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2584
Cell Significance Index: -29.6000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2675
Cell Significance Index: -56.3500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2931
Cell Significance Index: -42.6100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.3084
Cell Significance Index: -21.3300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.3709
Cell Significance Index: -5.0600 - Cell Name: early promyelocyte (CL0002154)
Fold Change: -0.3869
Cell Significance Index: -2.4700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.4201
Cell Significance Index: -45.6900 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.4249
Cell Significance Index: -5.9600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.4486
Cell Significance Index: -46.7100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.4532
Cell Significance Index: -34.7800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.4719
Cell Significance Index: -31.7300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4734
Cell Significance Index: -29.1000 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.4849
Cell Significance Index: -5.0200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5612
Cell Significance Index: -44.4500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.5620
Cell Significance Index: -16.1100 - Cell Name: epidermal cell (CL0000362)
Fold Change: -0.5633
Cell Significance Index: -1.2700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7029
Cell Significance Index: -43.1000 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -0.8003
Cell Significance Index: -5.0100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.8855
Cell Significance Index: -5.3500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2656049746
Symbol: GLU2B_HUMAN
Name: Glucosidase 2 subunit beta
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2793184
Title: Isolation of cDNAs encoding a substrate for protein kinase C: nucleotide sequence and chromosomal mapping of the gene for a human 80K protein.
PubMed ID: 2793184
PubMed ID: 9043864
Title: A 3-Mb region for the familial hemiplegic migraine locus on 19p13.1-p13.2: exclusion of PRKCSH as a candidate gene.
PubMed ID: 9043864
PubMed ID: 10929008
Title: The heterodimeric structure of glucosidase II is required for its activity, solubility, and localization in vivo.
PubMed ID: 10929008
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12665801
Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
PubMed ID: 12665801
DOI: 10.1038/nbt810
PubMed ID: 12529853
Title: Mutations in PRKCSH cause isolated autosomal dominant polycystic liver disease.
PubMed ID: 12529853
DOI: 10.1086/368295
PubMed ID: 12577059
Title: Germline mutations in PRKCSH are associated with autosomal dominant polycystic liver disease.
PubMed ID: 12577059
DOI: 10.1038/ng1104
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28375157
Title: Isolated polycystic liver disease genes define effectors of polycystin-1 function.
PubMed ID: 28375157
DOI: 10.1172/jci90129
Sequence Information:
- Length: 528
- Mass: 59425
- Checksum: 8DAD9776037E878E
- Sequence:
MLLPLLLLLP MCWAVEVKRP RGVSLTNHHF YDESKPFTCL DGSATIPFDQ VNDDYCDCKD GSDEPGTAAC PNGSFHCTNT GYKPLYIPSN RVNDGVCDCC DGTDEYNSGV ICENTCKEKG RKERESLQQM AEVTREGFRL KKILIEDWKK AREEKQKKLI ELQAGKKSLE DQVEMLRTVK EEAEKPEREA KEQHQKLWEE QLAAAKAQQE QELAADAFKE LDDDMDGTVS VTELQTHPEL DTDGDGALSE AEAQALLSGD TQTDATSFYD RVWAAIRDKY RSEALPTDLP APSAPDLTEP KEEQPPVPSS PTEEEEEEEE EEEEEAEEEE EEEDSEEAPP PLSPPQPASP AEEDKMPPYD EQTQAFIDAA QEARNKFEEA ERSLKDMEES IRNLEQEISF DFGPNGEFAY LYSQCYELTT NEYVYRLCPF KLVSQKPKLG GSPTSLGTWG SWIGPDHDKF SAMKYEQGTG CWQGPNRSTT VRLLCGKETM VTSTTEPSRC EYLMELMTPA ACPEPPPEAP TEDDHDEL
Genular Protein ID: 1658353379
Symbol: K7ELL7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 535
- Mass: 60192
- Checksum: 8A6ECA276C7B3C26
- Sequence:
MLLPLLLLLP MCWAVEVKRP RGVSLTNHHF YDESKPFTCL DGSATIPFDQ VNDDYCDCKD GSDEPGTAAC PNGSFHCTNT GYKPLYIPSN RVNDGVCDCC DGTDEYNSGV ICENTCKEKG RKERESLQQM AEVTREGFRL KKILIEDWKK AREEKQKKLI ELQAGKKSLE DQVEMLRTVK EEAEKPEREA KEQHQKLWEE QLAAAKAQQE QELAADAFKE LDDDMDGTVS VTELQTHPEL DTDGDGALSE AEAQALLSGD TQTDATSFYD RVWAAIRDKY RSEALPTDLP APSAPDLTEP KEEQPPVPSS PTEEEEEEEE EEEEEAEEEE EEEDSEVQGE QPKEAPPPLS PPQPASPAEE DKMPPYDEQT QAFIDAAQEA RNKFEEAERS LKDMEESIRN LEQEISFDFG PNGEFAYLYS QCYELTTNEY VYRLCPFKLV SQKPKLGGSP TSLGTWGSWI GPDHDKFSAM KYEQGTGCWQ GPNRSTTVRL LCGKETMVTS TTEPSRCEYL MELMTPAACP EPPPEAPTED DHDEL
Genular Protein ID: 2827994336
Symbol: B4DJQ5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 535
- Mass: 60134
- Checksum: 8A6E35146C7A9EB6
- Sequence:
MLLPLLLLLP MCWAVEVKRP RGVSLTNHHF YDESKPFTCL DGSATIPFDQ VNDDYCDCKD GSDEPGTAAC PNGSFHCTNT GYKPLYIPSN RVNDGVCDCC DGTDEYNSGV ICENTCKEKG RKERESLQQM AEVTREGFRL KKILIEDWKK AREEKQKKLI ELQAGKKSLE DQVEMLRTVK EEAEKPEREA KEQHQKLWEE QLAAAKAQQE QELAADAFKE LDDDMDGTVS VTELQTHPEL DTDGDGALSE AEAQALLSGD TQTDATSFYG RVWAAIRDKY RSEALPTDLP APSAPDLTEP KEEQPPVPSS PTEEEEEEEE EEEEEAEEEE EEEDSEVQGE QPKEAPPPLS PPQPASPAEE DKMPPYDEQT QAFIDAAQEA RNKFEEAERS LKDMEESIRN LEQEISFDFG PNGEFAYLYS QCYELTTNEY VYRLCPFKLV SQKPKLGGSP TSLGTWGSWI GPDHDKFSAM KYEQGTGCWQ GPNRSTTVRL LCGKETMVTS TTEPSRCEYL MELMTPAACP EPPPEAPTED DHDEL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.