Details for: MAPK7

Gene ID: 5598

Symbol: MAPK7

Ensembl ID: ENSG00000166484

Description: mitogen-activated protein kinase 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 68.4045
    Cell Significance Index: -10.6400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 42.5400
    Cell Significance Index: -10.7900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 28.8386
    Cell Significance Index: -11.8800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 23.9996
    Cell Significance Index: -9.7500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 21.7930
    Cell Significance Index: -11.2100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 10.2331
    Cell Significance Index: -9.7700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.9541
    Cell Significance Index: -11.0400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.0465
    Cell Significance Index: -10.8400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.8231
    Cell Significance Index: -11.1400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.5352
    Cell Significance Index: -3.3600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8524
    Cell Significance Index: 138.6300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7346
    Cell Significance Index: 663.2500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5498
    Cell Significance Index: 59.8000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.4922
    Cell Significance Index: 7.3800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4290
    Cell Significance Index: 49.9900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4161
    Cell Significance Index: 18.8600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3651
    Cell Significance Index: 10.5200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.3372
    Cell Significance Index: 4.6000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3296
    Cell Significance Index: 7.1400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3042
    Cell Significance Index: 21.0400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2186
    Cell Significance Index: 5.9500
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.2179
    Cell Significance Index: 2.7900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.2150
    Cell Significance Index: 4.5000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1852
    Cell Significance Index: 35.2400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1722
    Cell Significance Index: 4.6200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1471
    Cell Significance Index: 4.1100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1386
    Cell Significance Index: 19.0300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1344
    Cell Significance Index: 6.9800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1189
    Cell Significance Index: 4.1300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1080
    Cell Significance Index: 47.7700
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.0975
    Cell Significance Index: 1.0600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0831
    Cell Significance Index: 8.2300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0711
    Cell Significance Index: 2.5000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0703
    Cell Significance Index: 38.3800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0695
    Cell Significance Index: 12.5200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0685
    Cell Significance Index: 1.8000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0523
    Cell Significance Index: 6.4400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0481
    Cell Significance Index: 6.1700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0473
    Cell Significance Index: 9.3900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0387
    Cell Significance Index: 26.7900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0356
    Cell Significance Index: 7.1400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.0346
    Cell Significance Index: 0.6400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0283
    Cell Significance Index: 1.3200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0282
    Cell Significance Index: 0.6000
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.0271
    Cell Significance Index: 0.1800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0223
    Cell Significance Index: 7.9900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0143
    Cell Significance Index: 0.2400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0087
    Cell Significance Index: 1.0300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0079
    Cell Significance Index: 0.5600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0070
    Cell Significance Index: 0.9000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0059
    Cell Significance Index: 0.4400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0003
    Cell Significance Index: 0.5700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0062
    Cell Significance Index: -9.5900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0065
    Cell Significance Index: -12.0400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0078
    Cell Significance Index: -4.9500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0085
    Cell Significance Index: -11.6100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0092
    Cell Significance Index: -0.9400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0108
    Cell Significance Index: -7.9500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0120
    Cell Significance Index: -9.0600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0146
    Cell Significance Index: -10.8100
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.0167
    Cell Significance Index: -0.1400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0175
    Cell Significance Index: -7.9300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0185
    Cell Significance Index: -10.4400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0198
    Cell Significance Index: -1.2500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0222
    Cell Significance Index: -6.3800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0247
    Cell Significance Index: -0.5400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0247
    Cell Significance Index: -15.4200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0319
    Cell Significance Index: -4.6300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0339
    Cell Significance Index: -3.8800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0496
    Cell Significance Index: -8.4700
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.0593
    Cell Significance Index: -0.8500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0615
    Cell Significance Index: -2.8900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0634
    Cell Significance Index: -13.3600
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0645
    Cell Significance Index: -0.9800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0690
    Cell Significance Index: -4.4500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0731
    Cell Significance Index: -3.8100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0738
    Cell Significance Index: -1.9700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0744
    Cell Significance Index: -4.5700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0767
    Cell Significance Index: -2.2000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0900
    Cell Significance Index: -0.6100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1012
    Cell Significance Index: -1.1500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1032
    Cell Significance Index: -10.7500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1035
    Cell Significance Index: -3.0400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1062
    Cell Significance Index: -5.9600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1115
    Cell Significance Index: -8.5600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1168
    Cell Significance Index: -2.9200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1186
    Cell Significance Index: -3.8000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1282
    Cell Significance Index: -10.1500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1404
    Cell Significance Index: -8.6100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1428
    Cell Significance Index: -7.5000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1452
    Cell Significance Index: -9.7700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1512
    Cell Significance Index: -1.5700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1593
    Cell Significance Index: -4.2600
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: -0.1915
    Cell Significance Index: -1.1900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2030
    Cell Significance Index: -8.9800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2032
    Cell Significance Index: -2.9100
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.2357
    Cell Significance Index: -3.7400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2369
    Cell Significance Index: -8.9700
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.2377
    Cell Significance Index: -1.8000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2422
    Cell Significance Index: -8.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** MAPK7 is a non-canonical member of the MAPK family, which consists of three main subgroups: ERK (extracellular signal-regulated kinase), JNK (c-Jun N-terminal kinase), and p38 (p-38 mitogen-activated protein kinase). Unlike the canonical ERK and JNK pathways, which are activated by phosphorylation of specific residues, MAPK7 is activated by phosphorylation of its T-loop (Thr-273). This unique mechanism of activation distinguishes MAPK7 from other MAPKs. MAPK7 has a distinct tissue distribution, with high expression levels in immune cells, endothelial cells, and neural cells. It is also highly expressed in certain developmental stages and in response to specific stimuli, such as lipopolysaccharide (LPS) and interferon-gamma (IFN-γ). **Pathways and Functions** MAPK7 is involved in various cellular processes, including: 1. **Cell signaling**: MAPK7 is activated by growth factors, cytokines, and stress, leading to the phosphorylation and activation of downstream targets, such as transcription factors and kinases. 2. **Cell differentiation**: MAPK7 plays a role in regulating cell differentiation, particularly in immune cells and neural cells. 3. **Apoptosis**: MAPK7 can regulate apoptosis by modulating the activity of pro-apoptotic and anti-apoptotic proteins. 4. **Immune responses**: MAPK7 is involved in the regulation of immune responses, including the activation of immune cells and the production of cytokines. 5. **Cell cycle regulation**: MAPK7 can regulate cell cycle progression, particularly in response to DNA damage. 6. **Angiogenesis**: MAPK7 can regulate angiogenesis, the formation of new blood vessels. **Clinical Significance** MAPK7 has been implicated in various diseases, including: 1. **Inflammatory disorders**: MAPK7 has been shown to regulate inflammatory responses, making it a potential target for the treatment of inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease. 2. **Cancer**: MAPK7 has been implicated in cancer development and progression, particularly in immune cells and neural cells. 3. **Neurological disorders**: MAPK7 has been shown to regulate neural cell development and function, making it a potential target for the treatment of neurological disorders, such as Alzheimer's disease and Parkinson's disease. 4. **Cardiovascular disease**: MAPK7 has been implicated in the regulation of cardiovascular function, particularly in endothelial cells. In conclusion, MAPK7 is a complex protein involved in various cellular processes, including cell signaling, differentiation, and survival. Its dysregulation has been implicated in various diseases, making it a potential target for the development of new therapeutic strategies.

Genular Protein ID: 2171134850

Symbol: MK07_HUMAN

Name: Mitogen-activated protein kinase 7

UniProtKB Accession Codes:

Q13164 Q16634 Q59F50 Q6QLU7 Q7L4P4 Q969G1 Q96G51

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CPTAC 4 CTD 1 ChEBI 13 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 4 DrugCentral 1 EC 3 EMBL 12 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 32 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 13 PIR 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 6 RefSeq 5 Rhea 6 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7646528

Title: Primary structure of BMK1: a new mammalian map kinase.

PubMed ID: 7646528

DOI: 10.1006/bbrc.1995.2189

PubMed ID: 7759517

Title: Components of a new human protein kinase signal transduction pathway.

PubMed ID: 7759517

DOI: 10.1074/jbc.270.21.12665

PubMed ID: 15716121

Title: Identification and characterization of mErk5-T, a novel Erk5/Bmk1 splice variant.

PubMed ID: 15716121

DOI: 10.1016/j.gene.2004.11.011

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9384584

Title: BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C.

PubMed ID: 9384584

DOI: 10.1093/emboj/16.23.7054

PubMed ID: 9790194

Title: Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor.

PubMed ID: 9790194

DOI: 10.1038/27234

PubMed ID: 11254654

Title: BMK1 mediates growth factor-induced cell proliferation through direct cellular activation of serum and glucocorticoid-inducible kinase.

PubMed ID: 11254654

DOI: 10.1074/jbc.c000838200

PubMed ID: 11278431

Title: Granulocyte colony-stimulating factor induces ERK5 activation, which is differentially regulated by protein-tyrosine kinases and protein kinase C. Regulation of cell proliferation and survival.

PubMed ID: 11278431

DOI: 10.1074/jbc.m008748200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 20724525

Title: Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor.

PubMed ID: 20724525

DOI: 10.1096/fj.10-162636

PubMed ID: 23428871

Title: Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex.

PubMed ID: 23428871

DOI: 10.1128/mcb.01246-12

PubMed ID: 22869143

Title: BMK1 is involved in the regulation of p53 through disrupting the PML-MDM2 interaction.

PubMed ID: 22869143

DOI: 10.1038/onc.2012.332

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 816
  • Mass: 88386
  • Checksum: 27729FE31658CE3B
  • Sequence:
    • MAEPLKEEDG EDGSAEPPGP VKAEPAHTAA SVAAKNLALL KARSFDVTFD VGDEYEIIET 
IGNGAYGVVS SARRRLTGQQ VAIKKIPNAF DVVTNAKRTL RELKILKHFK HDNIIAIKDI 
LRPTVPYGEF KSVYVVLDLM ESDLHQIIHS SQPLTLEHVR YFLYQLLRGL KYMHSAQVIH 
RDLKPSNLLV NENCELKIGD FGMARGLCTS PAEHQYFMTE YVATRWYRAP ELMLSLHEYT 
QAIDLWSVGC IFGEMLARRQ LFPGKNYVHQ LQLIMMVLGT PSPAVIQAVG AERVRAYIQS 
LPPRQPVPWE TVYPGADRQA LSLLGRMLRF EPSARISAAA ALRHPFLAKY HDPDDEPDCA 
PPFDFAFDRE ALTRERIKEA IVAEIEDFHA RREGIRQQIR FQPSLQPVAS EPGCPDVEMP 
SPWAPSGDCA MESPPPAPPP CPGPAPDTID LTLQPPPPVS EPAPPKKDGA ISDNTKAALK 
AALLKSLRSR LRDGPSAPLE APEPRKPVTA QERQREREEK RRRRQERAKE REKRRQERER 
KERGAGASGG PSTDPLAGLV LSDNDRSLLE RWTRMARPAA PALTSVPAPA PAPTPTPTPV 
QPTSPPPGPV AQPTGPQPQS AGSTSGPVPQ PACPPPGPAP HPTGPPGPIP VPAPPQIATS 
TSLLAAQSLV PPPGLPGSST PGVLPYFPPG LPPPDAGGAP QSSMSESPDV NLVTQQLSKS 
QVEDPLPPVF SGTPKGSGAG YGVGFDLEEF LNQSFDMGVA DGPQDGQADS ASLSASLLAD 
WLEGHGMNPA DIESLQREIQ MDSPMLLADL PDLQDP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.