Details for: MAP2K2

Gene ID: 5605

Symbol: MAP2K2

Ensembl ID: ENSG00000126934

Description: mitogen-activated protein kinase kinase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 308.8491
    Cell Significance Index: -48.0400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 201.4245
    Cell Significance Index: -51.0900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 113.4239
    Cell Significance Index: -53.5500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 98.2338
    Cell Significance Index: -50.5300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 43.1321
    Cell Significance Index: -53.1800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.0595
    Cell Significance Index: -45.7000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.7821
    Cell Significance Index: -54.3900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 12.0489
    Cell Significance Index: -26.3700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.6427
    Cell Significance Index: -35.7600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 2.1841
    Cell Significance Index: 628.4400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.0457
    Cell Significance Index: 131.9800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.9035
    Cell Significance Index: 88.7500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.8947
    Cell Significance Index: 1034.7600
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.8241
    Cell Significance Index: 29.2700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.6549
    Cell Significance Index: 227.2600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.6286
    Cell Significance Index: 22.2200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.3528
    Cell Significance Index: 166.3400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.3174
    Cell Significance Index: 237.4800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.2954
    Cell Significance Index: 67.2900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2035
    Cell Significance Index: 130.9100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.1362
    Cell Significance Index: 146.7900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.0682
    Cell Significance Index: 50.2000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.0402
    Cell Significance Index: 73.5700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.0371
    Cell Significance Index: 458.5200
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.0245
    Cell Significance Index: 23.6700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.0147
    Cell Significance Index: 27.6200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.9817
    Cell Significance Index: 28.1400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.9687
    Cell Significance Index: 194.3200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8380
    Cell Significance Index: 166.3100
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.7417
    Cell Significance Index: 6.2300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.7071
    Cell Significance Index: 52.7000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.7067
    Cell Significance Index: 44.5400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.6524
    Cell Significance Index: 8.3600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.5545
    Cell Significance Index: 14.8100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5280
    Cell Significance Index: 52.2300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5170
    Cell Significance Index: 23.4400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4283
    Cell Significance Index: 153.6400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.2965
    Cell Significance Index: 2.7300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.2924
    Cell Significance Index: 6.1200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2658
    Cell Significance Index: 31.3500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2194
    Cell Significance Index: 28.1200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1521
    Cell Significance Index: 28.9500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0765
    Cell Significance Index: 13.0700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0346
    Cell Significance Index: 31.2500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0319
    Cell Significance Index: 23.3800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0116
    Cell Significance Index: 21.8900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0023
    Cell Significance Index: -4.1800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0097
    Cell Significance Index: -0.2700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0110
    Cell Significance Index: -16.9100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0138
    Cell Significance Index: -10.4600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0256
    Cell Significance Index: -34.8300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0392
    Cell Significance Index: -24.9000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0589
    Cell Significance Index: -43.6300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0661
    Cell Significance Index: -4.0600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0703
    Cell Significance Index: -31.9100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0857
    Cell Significance Index: -48.3300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0901
    Cell Significance Index: -3.1300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1004
    Cell Significance Index: -62.6800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1170
    Cell Significance Index: -11.9500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1391
    Cell Significance Index: -16.2100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1488
    Cell Significance Index: -5.2300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1577
    Cell Significance Index: -10.9100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.1702
    Cell Significance Index: -1.8500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2239
    Cell Significance Index: -3.7500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2239
    Cell Significance Index: -17.1900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2241
    Cell Significance Index: -15.0700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2310
    Cell Significance Index: -26.4600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2406
    Cell Significance Index: -34.9800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2677
    Cell Significance Index: -5.8000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2817
    Cell Significance Index: -59.3300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3035
    Cell Significance Index: -7.9800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3400
    Cell Significance Index: -26.9300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4637
    Cell Significance Index: -11.5900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4936
    Cell Significance Index: -51.4000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.5118
    Cell Significance Index: -25.8600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.5254
    Cell Significance Index: -29.4800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.5430
    Cell Significance Index: -9.5900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.5913
    Cell Significance Index: -8.8600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6007
    Cell Significance Index: -31.5400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.6462
    Cell Significance Index: -17.3200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6614
    Cell Significance Index: -40.5500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.6641
    Cell Significance Index: -19.1400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.6942
    Cell Significance Index: -18.5700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.7163
    Cell Significance Index: -13.2400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7167
    Cell Significance Index: -31.7000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.7622
    Cell Significance Index: -21.7500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.7687
    Cell Significance Index: -7.9600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.8151
    Cell Significance Index: -9.2600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.8617
    Cell Significance Index: -22.1500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.9013
    Cell Significance Index: -34.1300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.9529
    Cell Significance Index: -30.5200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.9634
    Cell Significance Index: -16.5100
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.9742
    Cell Significance Index: -8.2800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.0837
    Cell Significance Index: -6.5500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -1.1585
    Cell Significance Index: -47.4700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.1913
    Cell Significance Index: -41.7400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.2139
    Cell Significance Index: -44.5600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.2173
    Cell Significance Index: -39.8600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.2362
    Cell Significance Index: -39.3700
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -1.2377
    Cell Significance Index: -17.3600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Dual specificity kinase**: MAP2K2 has the ability to phosphorylate and activate both MAPKs and MAPK kinases, making it a key regulator of the MAPK signaling pathway. 2. **Highly expressed in various tissues**: MAP2K2 is expressed in multiple cell types, including pancreatic acinar cells, salivary gland acinar cells, early pro-B cells, cortical thymic epithelial cells, and enterocytes. 3. **Involved in numerous signaling pathways**: MAP2K2 is implicated in various signaling pathways, including those regulating cell growth, differentiation, apoptosis, immune responses, and disease. **Pathways and Functions:** 1. **MAPK signaling pathway**: MAP2K2 phosphorylates and activates MAPKs (e.g., ERK1/2), leading to the regulation of cell growth, differentiation, and survival. 2. **ERK1/2 activation**: MAP2K2 activates ERK1/2 by phosphorylating and activating MEK1/2, which in turn phosphorylates and activates ERK1/2. 3. **Cell growth and differentiation**: MAP2K2 regulates cell growth and differentiation by modulating the activity of downstream effectors, such as MAPKs and transcription factors. 4. **Immune responses**: MAP2K2 is involved in immune responses, including the regulation of immune cell development, activation, and function. 5. **Disease regulation**: MAP2K2 is implicated in various diseases, including cancer, where its dysregulation can lead to uncontrolled cell growth and tumor formation. **Clinical Significance:** 1. **Cancer therapy**: Targeting MAP2K2 and its downstream effectors may provide a new therapeutic strategy for cancer treatment. 2. **Neurological disorders**: MAP2K2 dysregulation has been implicated in various neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. 3. **Immune-related disorders**: MAP2K2 is involved in immune-related disorders, such as autoimmune diseases, where its dysregulation can lead to aberrant immune responses. 4. **Infectious diseases**: MAP2K2 is involved in the regulation of immune responses to bacterial toxins, such as anthrax. In conclusion, MAP2K2 is a key player in regulating various cellular processes, including cell growth, differentiation, survival, and immune responses. Its dysregulation has been implicated in various diseases, making it a potential target for therapeutic interventions. Further research is needed to fully understand the mechanisms of MAP2K2 and its role in disease regulation.

Genular Protein ID: 4176447098

Symbol: MP2K2_HUMAN

Name: Dual specificity mitogen-activated protein kinase kinase 2

UniProtKB Accession Codes:

P36507

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CPTAC 5 CPTC 1 CTD 1 ChEBI 18 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 6 DrugCentral 1 EC 3 EMBL 3 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 47 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 14 RefSeq 1 Rhea 9 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8388392

Title: Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.

PubMed ID: 8388392

DOI: 10.1016/s0021-9258(18)82142-1

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17116858

Title: Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling.

PubMed ID: 17116858

DOI: 10.1073/pnas.0608995103

PubMed ID: 9563949

Title: Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor.

PubMed ID: 9563949

DOI: 10.1126/science.280.5364.734

PubMed ID: 10409742

Title: Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization.

PubMed ID: 10409742

DOI: 10.1128/mcb.19.8.5523

PubMed ID: 11104681

Title: Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor.

PubMed ID: 11104681

DOI: 10.1042/bj3520739

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19447520

Title: Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration.

PubMed ID: 19447520

DOI: 10.1016/j.jhep.2009.02.027

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22538822

Title: Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.

PubMed ID: 22538822

DOI: 10.1073/pnas.1116573109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29433126

Title: MEK drives BRAF activation through allosteric control of KSR proteins.

PubMed ID: 29433126

DOI: 10.1038/nature25478

PubMed ID: 16439621

Title: Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome.

PubMed ID: 16439621

DOI: 10.1126/science.1124642

PubMed ID: 18042262

Title: Mutation and phenotypic spectrum in patients with cardio-facio-cutaneous and Costello syndrome.

PubMed ID: 18042262

DOI: 10.1111/j.1399-0004.2007.00931.x

PubMed ID: 20358587

Title: Molecular and functional analysis of a novel MEK2 mutation in cardio-facio-cutaneous syndrome: transmission through four generations.

PubMed ID: 20358587

DOI: 10.1002/ajmg.a.33342

Sequence Information:

  • Length: 400
  • Mass: 44424
  • Checksum: 3401D522515C30A5
  • Sequence:
    • MLARRKPVLP ALTINPTIAE GPSPTSEGAS EANLVDLQKK LEELELDEQQ KKRLEAFLTQ 
KAKVGELKDD DFERISELGA GNGGVVTKVQ HRPSGLIMAR KLIHLEIKPA IRNQIIRELQ 
VLHECNSPYI VGFYGAFYSD GEISICMEHM DGGSLDQVLK EAKRIPEEIL GKVSIAVLRG 
LAYLREKHQI MHRDVKPSNI LVNSRGEIKL CDFGVSGQLI DSMANSFVGT RSYMAPERLQ 
GTHYSVQSDI WSMGLSLVEL AVGRYPIPPP DAKELEAIFG RPVVDGEEGE PHSISPRPRP 
PGRPVSGHGM DSRPAMAIFE LLDYIVNEPP PKLPNGVFTP DFQEFVNKCL IKNPAERADL 
KMLTNHTFIK RSEVEEVDFA GWLCKTLRLN QPGTPTRTAV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.