Details for: MAP2K7

Gene ID: 5609

Symbol: MAP2K7

Ensembl ID: ENSG00000076984

Description: mitogen-activated protein kinase kinase 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 169.3398
    Cell Significance Index: -26.3400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 100.5349
    Cell Significance Index: -25.5000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 56.1058
    Cell Significance Index: -28.8600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 44.4695
    Cell Significance Index: -29.8400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 22.4744
    Cell Significance Index: -27.7100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.8027
    Cell Significance Index: -26.2600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.4150
    Cell Significance Index: -29.2600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.9739
    Cell Significance Index: -21.4200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.7748
    Cell Significance Index: -10.4500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.8722
    Cell Significance Index: 538.7000
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.5876
    Cell Significance Index: 25.4700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.3757
    Cell Significance Index: 18.7700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.2539
    Cell Significance Index: 34.1300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1859
    Cell Significance Index: 1070.7600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9345
    Cell Significance Index: 56.1000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.9286
    Cell Significance Index: 25.9500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7750
    Cell Significance Index: 126.0400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6738
    Cell Significance Index: 135.1700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.6636
    Cell Significance Index: 23.0600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6537
    Cell Significance Index: 129.7300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.6174
    Cell Significance Index: 32.4200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5748
    Cell Significance Index: 29.8600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5621
    Cell Significance Index: 25.4800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4908
    Cell Significance Index: 14.1400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4881
    Cell Significance Index: 87.9900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4835
    Cell Significance Index: 66.4000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4743
    Cell Significance Index: 58.3200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4536
    Cell Significance Index: 31.3700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4053
    Cell Significance Index: 145.3900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3780
    Cell Significance Index: 206.4100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3260
    Cell Significance Index: 21.0300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2979
    Cell Significance Index: 131.7300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.2666
    Cell Significance Index: 34.4500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2557
    Cell Significance Index: 11.9200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2389
    Cell Significance Index: 30.6300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2274
    Cell Significance Index: 16.9500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1933
    Cell Significance Index: 12.1800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1913
    Cell Significance Index: 8.9900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1578
    Cell Significance Index: 4.2300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1543
    Cell Significance Index: 106.6900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1411
    Cell Significance Index: 26.8500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1198
    Cell Significance Index: 14.1300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1074
    Cell Significance Index: 7.6000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0910
    Cell Significance Index: 6.9800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0695
    Cell Significance Index: 3.9000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0515
    Cell Significance Index: 5.0900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0168
    Cell Significance Index: 0.2000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0146
    Cell Significance Index: 27.5300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0131
    Cell Significance Index: 2.2400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0077
    Cell Significance Index: 14.2500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0075
    Cell Significance Index: 0.2000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0055
    Cell Significance Index: 8.4500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0023
    Cell Significance Index: 3.0600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0068
    Cell Significance Index: -4.3000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0089
    Cell Significance Index: -0.1900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0134
    Cell Significance Index: -9.8200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0175
    Cell Significance Index: -13.2600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0233
    Cell Significance Index: -10.5700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0322
    Cell Significance Index: -23.8400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0392
    Cell Significance Index: -4.0100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0449
    Cell Significance Index: -6.5200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0476
    Cell Significance Index: -26.8500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0526
    Cell Significance Index: -32.8600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0568
    Cell Significance Index: -2.0000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0608
    Cell Significance Index: -1.6000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0717
    Cell Significance Index: -1.2000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0883
    Cell Significance Index: -5.4300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0962
    Cell Significance Index: -11.2100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1390
    Cell Significance Index: -2.9100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1514
    Cell Significance Index: -31.8800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1569
    Cell Significance Index: -17.9700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1904
    Cell Significance Index: -12.8000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1959
    Cell Significance Index: -5.2400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1978
    Cell Significance Index: -3.3900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2360
    Cell Significance Index: -6.0300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2512
    Cell Significance Index: -7.2000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2554
    Cell Significance Index: -8.1800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2585
    Cell Significance Index: -26.9200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3181
    Cell Significance Index: -25.1900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3185
    Cell Significance Index: -6.9000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3237
    Cell Significance Index: -14.3200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3600
    Cell Significance Index: -22.0700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4106
    Cell Significance Index: -15.5500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.4369
    Cell Significance Index: -8.0800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4440
    Cell Significance Index: -11.1000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.4746
    Cell Significance Index: -5.1600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.4832
    Cell Significance Index: -14.1900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4878
    Cell Significance Index: -10.6800
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.5168
    Cell Significance Index: -11.9400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.5198
    Cell Significance Index: -15.3100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.5411
    Cell Significance Index: -10.5600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.5422
    Cell Significance Index: -8.1700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5423
    Cell Significance Index: -13.9400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5810
    Cell Significance Index: -16.5800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6249
    Cell Significance Index: -21.8900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6430
    Cell Significance Index: -20.4800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.6551
    Cell Significance Index: -24.0500
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.6551
    Cell Significance Index: -8.8400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.6637
    Cell Significance Index: -21.7300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.6733
    Cell Significance Index: -6.9700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** MAP2K7 shares significant sequence homology with other MAP2K family members, including MAP2K1, MAP2K2, and MAP2K5. However, MAP2K7 exhibits distinct differences in its substrate specificity and localization patterns. Notably, MAP2K7 is primarily localized to the cytosol and nucleus, where it interacts with various transcription factors and kinases to regulate gene expression and cellular responses. MAP2K7 is also known to be phosphorylated and activated by multiple upstream kinases, including TAK1, MyD88, and TRAF6, which are involved in immune system activation and inflammatory responses. **Pathways and Functions** MAP2K7 is involved in various signaling pathways that regulate cellular responses to stimuli, stress, and immune system activation. Some of the key pathways and functions of MAP2K7 include: 1. **Apoptotic Process**: MAP2K7 is involved in regulating apoptosis, a process of programmed cell death, by activating pro-apoptotic kinases and transcription factors. 2. **Cytokine Signaling**: MAP2K7 is involved in regulating cytokine signaling, including the activation of the JNK and p38 MAPK cascades, which are key regulators of immune responses. 3. **Innate Immune Response**: MAP2K7 is involved in regulating the innate immune response, including the activation of MyD88-dependent and MyD88-independent pathways. 4. **Cellular Stress Response**: MAP2K7 is involved in regulating the cellular stress response, including the activation of heat shock protein (HSP) pathways and the regulation of oxidative stress-induced senescence. 5. **Neuroprotection**: MAP2K7 has been implicated in neuroprotection, including the regulation of motor neuron apoptosis and the activation of anti-apoptotic kinases. **Clinical Significance** MAP2K7 has been implicated in various diseases and disorders, including: 1. **Neurodegenerative Diseases**: MAP2K7 has been implicated in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 2. **Cancer**: MAP2K7 has been implicated in cancer, including the regulation of cell growth, differentiation, and survival. 3. **Inflammatory Disorders**: MAP2K7 has been implicated in inflammatory disorders, including rheumatoid arthritis, atherosclerosis, and inflammatory bowel disease. 4. **Neurological Disorders**: MAP2K7 has been implicated in neurological disorders, including epilepsy, migraines, and stroke. In conclusion, MAP2K7 is a crucial gene involved in various signaling pathways that regulate cellular responses to stimuli, stress, and immune system activation. Its dysregulation has been implicated in various diseases and disorders, highlighting the importance of MAP2K7 in maintaining cellular homeostasis and overall health.

Genular Protein ID: 4276244849

Symbol: MP2K7_HUMAN

Name: Dual specificity mitogen-activated protein kinase kinase 7

UniProtKB Accession Codes:

O14733 B2R9S5 D6W659 O14648 O14816 O60452 O60453 Q1PG43 Q8IY10

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CPTAC 4 CTD 1 ChEBI 18 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 1 DrugCentral 1 EC 4 EMBL 11 Ensembl 3 EvolutionaryTrace 1 GO 35 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 36 PDBsum 36 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 4 RefSeq 3 Rhea 9 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9372971

Title: Molecular cloning and characterization of human JNKK2, a novel jun NH2-terminal kinase-specific kinase.

PubMed ID: 9372971

DOI: 10.1128/mcb.17.12.7407

PubMed ID: 9312068

Title: Identification of c-Jun NH2-terminal protein kinase (JNK)-activating kinase 2 as an activator of JNK but not p38.

PubMed ID: 9312068

DOI: 10.1074/jbc.272.40.24751

PubMed ID: 9535930

Title: Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli.

PubMed ID: 9535930

DOI: 10.1074/jbc.273.15.9344

PubMed ID: 16442502

Title: Cloning and expression of human mitogen-activated protein kinase kinase 7gamma1.

PubMed ID: 16442502

DOI: 10.1016/j.bbrc.2005.12.223

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9207092

Title: Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase.

PubMed ID: 9207092

DOI: 10.1073/pnas.94.14.7337

PubMed ID: 10490659

Title: The JIP group of mitogen-activated protein kinase scaffold proteins.

PubMed ID: 10490659

DOI: 10.1128/mcb.19.10.7245

PubMed ID: 11104681

Title: Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor.

PubMed ID: 11104681

DOI: 10.1042/bj3520739

PubMed ID: 12189133

Title: Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade.

PubMed ID: 12189133

DOI: 10.1074/jbc.m202004200

PubMed ID: 15866172

Title: Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases.

PubMed ID: 15866172

DOI: 10.1016/j.molcel.2005.04.001

PubMed ID: 18286207

Title: Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein.

PubMed ID: 18286207

DOI: 10.1371/journal.pone.0001660

PubMed ID: 17496909

Title: Differential regulation and properties of MAPKs.

PubMed ID: 17496909

DOI: 10.1038/sj.onc.1210392

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20801953

Title: Diverse physiological functions of MKK4 and MKK7 during early embryogenesis.

PubMed ID: 20801953

DOI: 10.1093/jb/mvq098

PubMed ID: 21278800

Title: RASSF7 negatively regulates pro-apoptotic JNK signaling by inhibiting the activity of phosphorylated-MKK7.

PubMed ID: 21278800

DOI: 10.1038/cdd.2010.137

PubMed ID: 21333379

Title: The bottleneck of JNK signaling: molecular and functional characteristics of MKK4 and MKK7.

PubMed ID: 21333379

DOI: 10.1016/j.ejcb.2010.11.008

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28111074

Title: ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Abeta Secretion.

PubMed ID: 28111074

DOI: 10.1016/j.cell.2016.12.044

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 419
  • Mass: 47485
  • Checksum: F1B22E050F54299A
  • Sequence:
    • MAASSLEQKL SRLEAKLKQE NREARRRIDL NLDISPQRPR PTLQLPLAND GGSRSPSSES 
SPQHPTPPAR PRHMLGLPST LFTPRSMESI EIDQKLQEIM KQTGYLTIGG QRYQAEINDL 
ENLGEMGSGT CGQVWKMRFR KTGHVIAVKQ MRRSGNKEEN KRILMDLDVV LKSHDCPYIV 
QCFGTFITNT DVFIAMELMG TCAEKLKKRM QGPIPERILG KMTVAIVKAL YYLKEKHGVI 
HRDVKPSNIL LDERGQIKLC DFGISGRLVD SKAKTRSAGC AAYMAPERID PPDPTKPDYD 
IRADVWSLGI SLVELATGQF PYKNCKTDFE VLTKVLQEEP PLLPGHMGFS GDFQSFVKDC 
LTKDHRKRPK YNKLLEHSFI KRYETLEVDV ASWFKDVMAK TESPRTSGVL SQPHLPFFR

Genular Protein ID: 18053596

Symbol: B4DV95_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DV95

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 IntAct 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 1 RefSeq 2 SAM 2 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 435
  • Mass: 49055
  • Checksum: 9C07E93DB2945B4E
  • Sequence:
    • MAASSLEQKL SRLEAKLKQE NREARRRIDL NLDISPQRPR PIIVITLSPA PAPSQRAALQ 
LPLANDGGSR SPSSESSPQH PTPPARPRHM LGLPSTLFTP RSMESIEIDQ KLQEIMKQTG 
YLTIGGQRYQ AEINDLENLG EMGSGTCGQV WKMRFRKTGH VIAVKQMRRS GNKEENKRIL 
MDLDVVLKSH DCPYIVQCFG TFITNTDVFI AMELMGTCAE KLKKRMQGPI PERILGKMTV 
AIVKALYYLK EKHGVIHRDV KPSNILLDER GQIKLCDFGI SGRLVDSKAK TRSAGCAAYM 
APERIDPPDP TKPDYDIRAD VWSLGISLVE LATGQFPYKN CKTDFEVLTK VLQEEPPPLP 
GHMGFSGDFQ SFVKDCLTKD HRKRPKYNKL LEHSFIKRYE TLEVDVASWF KDVMAKTESP 
RTSGVLSQPH LPFFR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.