Details for: PSMB3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: embryonic stem cell (CL0002322)
Fold Change: 183.4214
Cell Significance Index: -75.5600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 169.5478
Cell Significance Index: -68.8800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 155.0656
Cell Significance Index: -73.2100 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 142.2280
Cell Significance Index: -73.1600 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 109.4599
Cell Significance Index: -73.4500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 72.7630
Cell Significance Index: -69.4700 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 15.1517
Cell Significance Index: 156.8500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 12.8538
Cell Significance Index: -39.4800 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 11.6649
Cell Significance Index: 290.8900 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 10.2021
Cell Significance Index: -27.3300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 9.2594
Cell Significance Index: -20.2700 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 4.1471
Cell Significance Index: 76.6500 - Cell Name: abnormal cell (CL0001061)
Fold Change: 3.1487
Cell Significance Index: 321.6400 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 2.7237
Cell Significance Index: 29.6100 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.6526
Cell Significance Index: 69.7500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 2.3883
Cell Significance Index: 49.9900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.3350
Cell Significance Index: 109.7500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.3128
Cell Significance Index: 272.7500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.2269
Cell Significance Index: 165.9700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.1208
Cell Significance Index: 98.8800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.0961
Cell Significance Index: 135.2300 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 2.0131
Cell Significance Index: 22.8700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.8244
Cell Significance Index: 996.3500 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.7998
Cell Significance Index: 14.3700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.7524
Cell Significance Index: 47.7000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.6386
Cell Significance Index: 115.8900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.6133
Cell Significance Index: 198.3800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.5956
Cell Significance Index: 705.4400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.5846
Cell Significance Index: 257.7200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.5720
Cell Significance Index: 283.3800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.5456
Cell Significance Index: 92.7900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 1.3425
Cell Significance Index: 46.6500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.3183
Cell Significance Index: 181.0400 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.2560
Cell Significance Index: 162.2600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.1247
Cell Significance Index: 32.2400 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 1.1072
Cell Significance Index: 19.5700 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.0032
Cell Significance Index: 128.6100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.9508
Cell Significance Index: 49.3900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.8579
Cell Significance Index: 7.9000 - Cell Name: peg cell (CL4033014)
Fold Change: 0.7363
Cell Significance Index: 17.0100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.5819
Cell Significance Index: 30.5500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3643
Cell Significance Index: 36.0400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3141
Cell Significance Index: 9.0500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2901
Cell Significance Index: 58.1900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.2454
Cell Significance Index: 185.7700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.2398
Cell Significance Index: 12.4900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2354
Cell Significance Index: 46.7100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1547
Cell Significance Index: 29.4400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1374
Cell Significance Index: 8.6600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1211
Cell Significance Index: 20.6800 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.1069
Cell Significance Index: 1.6000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0584
Cell Significance Index: 1.5600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0395
Cell Significance Index: 28.9700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0339
Cell Significance Index: 1.0900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0166
Cell Significance Index: 5.9400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0201
Cell Significance Index: -37.9400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0374
Cell Significance Index: -1.8900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0437
Cell Significance Index: -80.6100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0542
Cell Significance Index: -83.4200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0673
Cell Significance Index: -91.5400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0698
Cell Significance Index: -51.7400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0818
Cell Significance Index: -51.9700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1121
Cell Significance Index: -63.2400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1348
Cell Significance Index: -61.2000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1399
Cell Significance Index: -87.3700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1445
Cell Significance Index: -16.5500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2405
Cell Significance Index: -6.7200 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.2482
Cell Significance Index: -10.1700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2535
Cell Significance Index: -72.9300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2619
Cell Significance Index: -6.6900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2894
Cell Significance Index: -33.7300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.3101
Cell Significance Index: -33.7300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3376
Cell Significance Index: -71.1100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3856
Cell Significance Index: -56.0500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.5343
Cell Significance Index: -24.2200 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: -0.5400
Cell Significance Index: -4.6400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5672
Cell Significance Index: -44.9200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.5871
Cell Significance Index: -40.6000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.6698
Cell Significance Index: -11.2100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.6752
Cell Significance Index: -70.3100 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.7748
Cell Significance Index: -22.8200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.7847
Cell Significance Index: -60.2200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.8377
Cell Significance Index: -47.0100 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: -0.8878
Cell Significance Index: -6.9000 - Cell Name: radial glial cell (CL0000681)
Fold Change: -0.8889
Cell Significance Index: -5.2800 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.9777
Cell Significance Index: -13.3400 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -1.0587
Cell Significance Index: -14.8500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -1.1338
Cell Significance Index: -14.5200 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -1.1342
Cell Significance Index: -6.9800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.1562
Cell Significance Index: -29.7200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.1590
Cell Significance Index: -25.1100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.1928
Cell Significance Index: -73.1300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -1.2695
Cell Significance Index: -7.6700 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -1.4607
Cell Significance Index: -12.2700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.4636
Cell Significance Index: -64.7400 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -1.5227
Cell Significance Index: -26.2500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -1.6328
Cell Significance Index: -59.9400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -1.6450
Cell Significance Index: -28.1900 - Cell Name: hepatoblast (CL0005026)
Fold Change: -1.6511
Cell Significance Index: -27.7700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.6596
Cell Significance Index: -58.1400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2383033972
Symbol: PSB3_HUMAN
Name: Proteasome chain 13
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7918633
Title: Sequence analyses and inter-species comparisons of three novel human proteasomal subunits, HsN3, HsC7-I and HsC10-II, confine potential proteolytic active-site residues.
PubMed ID: 7918633
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1286667
Title: Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.
PubMed ID: 1286667
PubMed ID: 7811265
Title: Human proteasome subunits from 2-dimensional gels identified by partial sequencing.
PubMed ID: 7811265
PubMed ID: 8610016
Title: A role for the proteasome regulator PA28alpha in antigen presentation.
PubMed ID: 8610016
DOI: 10.1038/381166a0
PubMed ID: 12181345
Title: Clastosome: a subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome.
PubMed ID: 12181345
PubMed ID: 14550573
Title: Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits.
PubMed ID: 14550573
PubMed ID: 15244466
Title: 20S proteasome prevents aggregation of heat-denatured proteins without PA700 regulatory subcomplex like a molecular chaperone.
PubMed ID: 15244466
DOI: 10.1021/bm049957a
PubMed ID: 17323924
Title: Mass spectrometric characterization of the affinity-purified human 26S proteasome complex.
PubMed ID: 17323924
DOI: 10.1021/bi061994u
PubMed ID: 18281682
Title: Identification of proteomic differences in asthenozoospermic sperm samples.
PubMed ID: 18281682
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 23495936
Title: Molecular architecture and assembly of the eukaryotic proteasome.
PubMed ID: 23495936
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 27176742
Title: Human 20S proteasome activity towards fluorogenic peptides of various chain lengths.
PubMed ID: 27176742
PubMed ID: 26133119
Title: Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core.
PubMed ID: 26133119
DOI: 10.1038/ncomms8573
PubMed ID: 25599644
Title: Crystal structure of the human 20S proteasome in complex with carfilzomib.
PubMed ID: 25599644
PubMed ID: 27428775
PubMed ID: 27342858
Title: Structure of the human 26S proteasome at a resolution of 3.9 Aa.
PubMed ID: 27342858
PubMed ID: 27493187
Title: The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
PubMed ID: 27493187
PubMed ID: 34711951
Title: AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
PubMed ID: 34711951
Sequence Information:
- Length: 205
- Mass: 22949
- Checksum: 624972384C0112FD
- Sequence:
MSIMSYNGGA VMAMKGKNCV AIAADRRFGI QAQMVTTDFQ KIFPMGDRLY IGLAGLATDV QTVAQRLKFR LNLYELKEGR QIKPYTLMSM VANLLYEKRF GPYYTEPVIA GLDPKTFKPF ICSLDLIGCP MVTDDFVVSG TCAEQMYGMC ESLWEPNMDP DHLFETISQA MLNAVDRDAV SGMGVIVHII EKDKITTRTL KARMD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.