Details for: RHEB

Gene ID: 6009

Symbol: RHEB

Ensembl ID: ENSG00000106615

Description: Ras homolog, mTORC1 binding

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 460.1877
    Cell Significance Index: -71.5800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 321.9087
    Cell Significance Index: -81.6500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 203.6303
    Cell Significance Index: -83.8900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 197.5228
    Cell Significance Index: -93.2600
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 160.6772
    Cell Significance Index: -82.6500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 139.4067
    Cell Significance Index: -93.5500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 73.4820
    Cell Significance Index: -90.6000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 24.9621
    Cell Significance Index: -66.8700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 23.5856
    Cell Significance Index: -93.0700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 19.0203
    Cell Significance Index: -58.4200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 15.3981
    Cell Significance Index: -33.7000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 4.2239
    Cell Significance Index: 121.0800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 3.5713
    Cell Significance Index: 187.5100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.4127
    Cell Significance Index: 92.8900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 3.0001
    Cell Significance Index: 141.0000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.5989
    Cell Significance Index: 422.6900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.5954
    Cell Significance Index: 23.9000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2.5849
    Cell Significance Index: 69.0200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.1589
    Cell Significance Index: 278.9200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.1222
    Cell Significance Index: 158.1600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.8111
    Cell Significance Index: 24.7100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.7905
    Cell Significance Index: 62.2200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.7184
    Cell Significance Index: 89.2700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.7129
    Cell Significance Index: 308.7800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7047
    Cell Significance Index: 341.9500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.7030
    Cell Significance Index: 44.7800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.6776
    Cell Significance Index: 206.2700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.5577
    Cell Significance Index: 213.9200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.5398
    Cell Significance Index: 27.2100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.3709
    Cell Significance Index: 63.9200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.3649
    Cell Significance Index: 28.5700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3032
    Cell Significance Index: 258.6200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.2919
    Cell Significance Index: 165.6200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.2004
    Cell Significance Index: 1083.9100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.1092
    Cell Significance Index: 490.3900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.0120
    Cell Significance Index: 362.9800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9937
    Cell Significance Index: 542.7000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.9871
    Cell Significance Index: 55.3900
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.8604
    Cell Significance Index: 5.3000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.8008
    Cell Significance Index: 61.4600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.7153
    Cell Significance Index: 50.5900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.6485
    Cell Significance Index: 7.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.5870
    Cell Significance Index: 1105.2900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.4690
    Cell Significance Index: 80.0900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.4521
    Cell Significance Index: 11.6200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4427
    Cell Significance Index: 306.1800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2558
    Cell Significance Index: 16.5100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2161
    Cell Significance Index: 21.3800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1797
    Cell Significance Index: 114.1100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1113
    Cell Significance Index: 13.1200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0816
    Cell Significance Index: 1.3700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0765
    Cell Significance Index: 57.8900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0645
    Cell Significance Index: 7.3600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0398
    Cell Significance Index: 18.0600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0279
    Cell Significance Index: 20.4200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.0167
    Cell Significance Index: 0.1900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0080
    Cell Significance Index: 12.3200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0045
    Cell Significance Index: 8.2900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0197
    Cell Significance Index: -26.8100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0307
    Cell Significance Index: -22.7400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0515
    Cell Significance Index: -32.1600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0582
    Cell Significance Index: -5.9500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0986
    Cell Significance Index: -55.5900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.1566
    Cell Significance Index: -29.8100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1808
    Cell Significance Index: -38.0900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.1949
    Cell Significance Index: -21.2000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2405
    Cell Significance Index: -28.0300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2530
    Cell Significance Index: -36.7800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2607
    Cell Significance Index: -29.8700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2617
    Cell Significance Index: -17.6000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2668
    Cell Significance Index: -76.7800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.3722
    Cell Significance Index: -16.8700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3874
    Cell Significance Index: -23.8100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.4872
    Cell Significance Index: -17.1200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4944
    Cell Significance Index: -21.8700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5111
    Cell Significance Index: -14.5900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.5239
    Cell Significance Index: -14.6400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5288
    Cell Significance Index: -33.3300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5816
    Cell Significance Index: -60.5600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.5890
    Cell Significance Index: -12.7600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5938
    Cell Significance Index: -47.0300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.6010
    Cell Significance Index: -17.6500
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.6107
    Cell Significance Index: -3.6900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6908
    Cell Significance Index: -26.1600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.7295
    Cell Significance Index: -17.8000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.7706
    Cell Significance Index: -12.9800
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.9359
    Cell Significance Index: -5.8200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.9410
    Cell Significance Index: -21.7400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.9782
    Cell Significance Index: -24.9900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.1606
    Cell Significance Index: -31.0500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.2704
    Cell Significance Index: -23.4800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.3151
    Cell Significance Index: -42.1200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.3918
    Cell Significance Index: -85.3300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.4373
    Cell Significance Index: -21.2200
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -1.4513
    Cell Significance Index: -15.4200
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -1.5280
    Cell Significance Index: -12.2000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.5332
    Cell Significance Index: -38.3300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.5869
    Cell Significance Index: -46.7400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -1.7465
    Cell Significance Index: -26.1700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -1.8141
    Cell Significance Index: -21.6300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RHEB is a member of the Ras superfamily of small GTPases, characterized by its GTP-binding domain and ability to bind to mTORC1. Its expression is highly specific to certain cell types, including fibroblasts of mammary gland, basal cells of prostate epithelium, and skeletal muscle satellite stem cells. RHEB exhibits a unique ability to activate the PI3K/AKT signaling pathway, which is essential for cell survival and proliferation. **Pathways and Functions:** RHEB's primary function is to regulate mTORC1 activity, which in turn modulates various cellular processes, including: 1. **Autophagy**: RHEB promotes autophagy by activating mTORC1, which leads to the degradation of damaged organelles and proteins. 2. **Energy Metabolism**: RHEB regulates energy metabolism by modulating mTORC1 activity, which affects glucose and lipid metabolism. 3. **Cellular Responses to Stress**: RHEB plays a crucial role in regulating cellular responses to stress, including nutrient deprivation and hypoxia. 4. **Cellular Response to Nutrient Levels**: RHEB modulates mTORC1 activity in response to changes in nutrient levels, ensuring that cells respond appropriately to nutrient availability. 5. **Cellular Response to Starvation**: RHEB promotes autophagy and energy metabolism in response to starvation, ensuring cell survival. **Clinical Significance:** RHEB's dysregulation has been implicated in various disease states, including: 1. **Cancer**: RHEB overexpression has been observed in various types of cancer, including prostate and breast cancer, where it promotes cell growth and survival. 2. **Neurodegenerative Diseases**: RHEB's role in regulating energy metabolism and autophagy makes it a potential target for neurodegenerative diseases, such as Alzheimer's and Parkinson's. 3. **Metabolic Disorders**: RHEB's regulation of energy metabolism and autophagy makes it a potential target for metabolic disorders, such as obesity and type 2 diabetes. 4. **Muscular Dystrophy**: RHEB's role in regulating muscle growth and development makes it a potential target for muscular dystrophy. In conclusion, RHEB is a critical regulator of cellular signaling pathways, including autophagy, energy metabolism, and cellular responses to stress and nutrient levels. Its dysregulation has been implicated in various disease states, making it a potential target for therapeutic interventions. Further research is needed to fully elucidate the role of RHEB in human disease and to explore its therapeutic potential.

Genular Protein ID: 1768077810

Symbol: RHEB_HUMAN

Name: Ras homolog enriched in brain

UniProtKB Accession Codes:

Q15382 B3KWN6 D3DX13 Q53Y56 Q99444

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 29 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 2 EMBL 10 EMDB 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 28 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 12 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 7 RefSeq 1 Rhea 2 SABIO-RK 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8543055

Title: A novel approach for expression cloning of small GTPases: identification, tissue distribution and chromosome mapping of the human homolog of rheb.

PubMed ID: 8543055

DOI: 10.1016/0014-5793(95)01349-0

PubMed ID: 8661031

Title: Isolation of cDNA and genomic clones of a human Ras-related GTP-binding protein gene and its chromosomal localization to the long arm of chromosome 7, 7q36.

PubMed ID: 8661031

DOI: 10.1006/geno.1996.0248

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12172553

Title: TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.

PubMed ID: 12172553

DOI: 10.1038/ncb839

PubMed ID: 12906785

Title: Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.

PubMed ID: 12906785

DOI: 10.1016/s0960-9822(03)00506-2

PubMed ID: 12271141

Title: Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.

PubMed ID: 12271141

DOI: 10.1073/pnas.202476899

PubMed ID: 12842888

Title: Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner.

PubMed ID: 12842888

DOI: 10.1074/jbc.c300226200

PubMed ID: 12869586

Title: Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.

PubMed ID: 12869586

DOI: 10.1101/gad.1110003

PubMed ID: 15340059

Title: Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.

PubMed ID: 15340059

DOI: 10.1128/mcb.24.18.7965-7975.2004

PubMed ID: 15308774

Title: A tagging-via-substrate technology for detection and proteomics of farnesylated proteins.

PubMed ID: 15308774

DOI: 10.1073/pnas.0403413101

PubMed ID: 15854902

Title: Rheb binds and regulates the mTOR kinase.

PubMed ID: 15854902

DOI: 10.1016/j.cub.2005.02.053

PubMed ID: 16098514

Title: Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1.

PubMed ID: 16098514

DOI: 10.1016/j.febslet.2005.07.054

PubMed ID: 20381137

Title: Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.

PubMed ID: 20381137

DOI: 10.1016/j.cell.2010.02.024

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24529379

Title: Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.

PubMed ID: 24529379

DOI: 10.1016/j.cell.2013.11.049

PubMed ID: 30514904

Title: Ubiquitination of Rheb governs growth factor-induced mTORC1 activation.

PubMed ID: 30514904

DOI: 10.1038/s41422-018-0120-9

PubMed ID: 33157014

Title: Amino acids enhance polyubiquitination of Rheb and its binding to mTORC1 by blocking lysosomal ATXN3 deubiquitinase activity.

PubMed ID: 33157014

DOI: 10.1016/j.molcel.2020.10.004

PubMed ID: 15728574

Title: Structural basis for the unique biological function of small GTPase RHEB.

PubMed ID: 15728574

DOI: 10.1074/jbc.m501253200

PubMed ID: 22002721

Title: Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo.

PubMed ID: 22002721

DOI: 10.1038/nchembio.686

PubMed ID: 22819219

Title: An autoinhibited noncanonical mechanism of GTP hydrolysis by Rheb maintains mTORC1 homeostasis.

PubMed ID: 22819219

DOI: 10.1016/j.str.2012.06.013

PubMed ID: 29236692

Title: Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.

PubMed ID: 29236692

DOI: 10.1038/nature25023

PubMed ID: 29416044

Title: A small molecule inhibitor of Rheb selectively targets mTORC1 signaling.

PubMed ID: 29416044

DOI: 10.1038/s41467-018-03035-z

PubMed ID: 32470140

Title: Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.

PubMed ID: 32470140

DOI: 10.1093/jmcb/mjaa025

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 184
  • Mass: 20497
  • Checksum: 8F4C8080BDF928FD
  • Sequence:
    • MPQSKSRKIA ILGYRSVGKS SLTIQFVEGQ FVDSYDPTIE NTFTKLITVN GQEYHLQLVD 
TAGQDEYSIF PQTYSIDING YILVYSVTSI KSFEVIKVIH GKLLDMVGKV QIPIMLVGNK 
KDLHMERVIS YEEGKALAES WNAAFLESSA KENQTAVDVF RRIILEAEKM DGAASQGKSS 
CSVM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.