Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 358.4809
Cell Significance Index: -55.7600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 220.5459
Cell Significance Index: -55.9400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 110.1273
Cell Significance Index: -44.7400 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 47.1331
Cell Significance Index: -45.0000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 46.1736
Cell Significance Index: -56.9300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 20.1018
Cell Significance Index: -53.8500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 15.4813
Cell Significance Index: -47.5500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 14.5462
Cell Significance Index: -57.4000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 11.8752
Cell Significance Index: -25.9900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 2.5297
Cell Significance Index: 481.4100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.1894
Cell Significance Index: 439.2000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.9676
Cell Significance Index: 110.4100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.5451
Cell Significance Index: 152.8400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.3580
Cell Significance Index: 220.8700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.3290
Cell Significance Index: 263.7400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.3287
Cell Significance Index: 476.5800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.3238
Cell Significance Index: 1195.3100 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.2118
Cell Significance Index: 15.0300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.1888
Cell Significance Index: 91.2300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.0310
Cell Significance Index: 713.0600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.8865
Cell Significance Index: 39.2100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.8268
Cell Significance Index: 31.3100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.7891
Cell Significance Index: 48.5000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.7717
Cell Significance Index: 51.8900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.7354
Cell Significance Index: 21.0800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.7112
Cell Significance Index: 77.3600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.5750
Cell Significance Index: 14.7800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5407
Cell Significance Index: 66.4900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.5161
Cell Significance Index: 971.7100 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.5083
Cell Significance Index: 9.9200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.4907
Cell Significance Index: 222.7300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.4811
Cell Significance Index: 86.7400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.4171
Cell Significance Index: 25.0400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3942
Cell Significance Index: 17.8700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.3540
Cell Significance Index: 18.4400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3499
Cell Significance Index: 191.0700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.3324
Cell Significance Index: 211.1200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2979
Cell Significance Index: 131.7000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2798
Cell Significance Index: 38.4300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2723
Cell Significance Index: 7.8500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2719
Cell Significance Index: 5.8900 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.2616
Cell Significance Index: 6.2800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2560
Cell Significance Index: 394.1500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2351
Cell Significance Index: 16.2600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.2208
Cell Significance Index: 300.2100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1900
Cell Significance Index: 5.3100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.1684
Cell Significance Index: 4.5800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1672
Cell Significance Index: 308.4400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1424
Cell Significance Index: 2.4400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1296
Cell Significance Index: 6.7300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.1248
Cell Significance Index: 3.5600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0847
Cell Significance Index: 10.8600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0620
Cell Significance Index: 1.5500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0482
Cell Significance Index: 5.6900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.0423
Cell Significance Index: 0.9100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0007
Cell Significance Index: 0.0200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0206
Cell Significance Index: -3.0000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0263
Cell Significance Index: -0.9300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0411
Cell Significance Index: -0.9000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0489
Cell Significance Index: -35.8500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0594
Cell Significance Index: -44.0100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.0596
Cell Significance Index: -0.3600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0738
Cell Significance Index: -55.8300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1014
Cell Significance Index: -57.1700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1014
Cell Significance Index: -63.3500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1189
Cell Significance Index: -5.5900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1418
Cell Significance Index: -24.2200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1679
Cell Significance Index: -48.3000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1774
Cell Significance Index: -8.2700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.2263
Cell Significance Index: -6.0700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2337
Cell Significance Index: -12.2700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2458
Cell Significance Index: -25.1100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2473
Cell Significance Index: -17.4900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2622
Cell Significance Index: -33.8700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2713
Cell Significance Index: -31.6200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2763
Cell Significance Index: -28.7700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2893
Cell Significance Index: -60.9400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3315
Cell Significance Index: -21.3900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3365
Cell Significance Index: -21.2100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3748
Cell Significance Index: -42.9400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.3775
Cell Significance Index: -5.1500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.4663
Cell Significance Index: -34.7500 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.4796
Cell Significance Index: -7.0800 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.5380
Cell Significance Index: -11.1600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.5836
Cell Significance Index: -12.4300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5948
Cell Significance Index: -47.1100 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.6021
Cell Significance Index: -8.6600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.6381
Cell Significance Index: -15.5700 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.6588
Cell Significance Index: -9.4600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.6762
Cell Significance Index: -17.7800 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.7684
Cell Significance Index: -9.1600 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.8971
Cell Significance Index: -7.3200 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.9038
Cell Significance Index: -11.2700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.9099
Cell Significance Index: -55.7800 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.9652
Cell Significance Index: -7.4400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.9804
Cell Significance Index: -34.0700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.9863
Cell Significance Index: -31.5900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -1.0645
Cell Significance Index: -28.4800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -1.1077
Cell Significance Index: -23.5100 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -1.1298
Cell Significance Index: -14.2600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 124708584
Symbol: RLF_HUMAN
Name: Zinc finger protein Rlf
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8545128
Title: The rearranged L-myc fusion gene (RLF) encodes a Zn-15 related zinc finger protein.
PubMed ID: 8545128
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 1914
- Mass: 217953
- Checksum: 105C85C645563999
- Sequence:
MADGKGDAAA VAGAGAEAPA VAGAGDGVET ESMVRGHRPV SPAPGASGLR PCLWQLETEL REQEVSEVSS LNYCRSFCQT LLQYASNKNA SEHIVYLLEV YRLAIQSFAS ARPYLTTECE DVLLVLGRLV LSCFELLLSV SESELPCEVW LPFLQSLQES HDALLEFGNN NLQILVHVTK EGVWKNPVLL KILSQQPVET EEVNKLIAQE GPSFLQMRIK HLLKSNCIPQ ATALSKLCAE SKEISNVSSF QQAYITCLCS MLPNEDAIKE IAKVDCKEVL DIICNLESEG QDNTAFVLCT TYLTQQLQTA SVYCSWELTL FWSKLQRRID PSLDTFLERC RQFGVIAKTQ QHLFCLIRVI QTEAQDAGLG VSILLCVRAL QLRSSEDEEM KASVCKTIAC LLPEDLEVRR ACQLTEFLIE PSLDGFNMLE ELYLQPDQKF DEENAPVPNS LRCELLLALK AHWPFDPEFW DWKTLKRHCH QLLGQEASDS DDDLSGYEMS INDTDVLESF LSDYDEGKED KQYRRRDLTD QHKEKRDKKP IGSSERYQRW LQYKFFCLLC KRECIEARIL HHSKMHMEDG IYTCPVCIKK FKRKEMFVPH VMEHVKMPPS RRDRSKKKLL LKGSQKGICP KSPSAIPEQN HSLNDQAKGE SHEYVTFSKL EDCHLQDRDL YPCPGTDCSR VFKQFKYLSV HLKAEHQNND ENAKHYLDMK NRREKCTYCR RHFMSAFHLR EHEQVHCGPQ PYMCVSIDCY ARFGSVNELL NHKQKHDDLR YKCELNGCNI VFSDLGQLYH HEAQHFRDAS YTCNFLGCKK FYYSKIEYQN HLSMHNVENS NGDIKKSVKL EESATGEKQD CINQPHLLNQ TDKSHLPEDL FCAESANSQI DTETAENLKE NSDSNSSDQL SHSSSASMNE ELIDTLDHSE TMQDVLLSNE KVFGPSSLKE KCSSMAVCFD GTKFTCGFDG CGSTYKNARG MQKHLRKVHP YHFKPKKIKT KDLFPSLGNE HNQTTEKLDA EPKPCSDTNS DSPDEGLDHN IHIKCKREHQ GYSSESSICA SKRPCTEDTM LELLLRLKHL SLKNSITHGS FSGSLQGYPS SGAKSLQSVS SISDLNFQNQ DENMPSQYLA QLAAKPFFCE LQGCKYEFVT REALLMHYLK KHNYSKEKVL QLTMFQHRYS PFQCHICQRS FTRKTHLRIH YKNKHQIGSD RATHKLLDNE KCDHEGPCSV DRLKGDCSAE LGGDPSSNSE KPHCHPKKDE CSSETDLESS CEETESKTSD ISSPIGSHRE EQEGREGRGS RRTVAKGNLC YILNKYHKPF HCIHKTCNSS FTNLKGLIRH YRTVHQYNKE QLCLEKDKAR TKRELVKCKK IFACKYKECN KRFLCSKALA KHCSDSHNLD HIEEPKVLSE AGSAARFSCN QPQCPAVFYT FNKLKHHLME QHNIEGEIHS DYEIHCDLNG CGQIFTHRSN YSQHVYYRHK DYYDDLFRSQ KVANERLLRS EKVCQTADTQ GHEHQTTRRS FNAKSKKCGL IKEKKAPISF KTRAEALHMC VEHSEHTQYP CMVQGCLSVV KLESSIVRHY KRTHQMSSAY LEQQMENLVV CVKYGTKIKE EPPSEADPCI KKEENRSCES ERTEHSHSPG DSSAPIQNTD CCHSSERDGG QKGCIESSSV FDADTLLYRG TLKCNHSSKT TSLEQCNIVQ PPPPCKIENS IPNPNGTESG TYFTSFQLPL PRIKESETRQ HSSGQENTVK NPTHVPKENF RKHSQPRSFD LKTYKPMGFE SSFLKFIQES EEKEDDFDDW EPSEHLTLSN SSQSSNDLTG NVVANNMVND SEPEVDIPHS SSDSTIHENL TAIPPLIVAE TTTVPSLENL RVVLDKALTD CGELALKQLH YLRPVVVLER SKFSTPILDL FPTKKTDELC VGSS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.