Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 246.4878
Cell Significance Index: -38.3400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 153.5029
Cell Significance Index: -38.9400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 82.0416
Cell Significance Index: -33.3300 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 58.2842
Cell Significance Index: -39.1100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 34.9309
Cell Significance Index: -33.3500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 31.5502
Cell Significance Index: -38.9000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 14.5230
Cell Significance Index: -38.9100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 10.4869
Cell Significance Index: -32.2100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.8890
Cell Significance Index: -39.0200 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 9.3530
Cell Significance Index: 57.5600 - Cell Name: epidermal cell (CL0000362)
Fold Change: 7.7401
Cell Significance Index: 17.4500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 7.3048
Cell Significance Index: 198.8300 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 6.0457
Cell Significance Index: 17.9800 - Cell Name: columnar/cuboidal epithelial cell (CL0000075)
Fold Change: 4.3353
Cell Significance Index: 16.6000 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 4.2820
Cell Significance Index: 72.1300 - Cell Name: lactocyte (CL0002325)
Fold Change: 4.1651
Cell Significance Index: 538.1100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 3.9613
Cell Significance Index: 295.2300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 3.9569
Cell Significance Index: -8.6600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.5212
Cell Significance Index: 130.9700 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 2.3228
Cell Significance Index: 21.3900 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 1.8636
Cell Significance Index: 45.4700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.8188
Cell Significance Index: 197.8300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.7660
Cell Significance Index: 318.3600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 1.7479
Cell Significance Index: 82.1500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.7378
Cell Significance Index: 768.3400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.4866
Cell Significance Index: 69.3100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.4672
Cell Significance Index: 66.5100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.4113
Cell Significance Index: 37.8200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.3918
Cell Significance Index: 171.1400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.3892
Cell Significance Index: 98.2500 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 1.2763
Cell Significance Index: 7.9300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.1631
Cell Significance Index: 33.3400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.1052
Cell Significance Index: 31.8400 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.0982
Cell Significance Index: 16.4600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.0978
Cell Significance Index: 599.5300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.0280
Cell Significance Index: 195.6300 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.9945
Cell Significance Index: 6.1600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.6269
Cell Significance Index: 124.4200 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.5873
Cell Significance Index: 8.3600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.5229
Cell Significance Index: 40.1300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4940
Cell Significance Index: 48.8700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4847
Cell Significance Index: 10.5000 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 0.4655
Cell Significance Index: 6.5100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4620
Cell Significance Index: 417.1400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.4094
Cell Significance Index: 309.8900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.3670
Cell Significance Index: 12.9000 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.3663
Cell Significance Index: 4.0700 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.3533
Cell Significance Index: 5.2200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.3471
Cell Significance Index: 44.5000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.3458
Cell Significance Index: 59.0500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3299
Cell Significance Index: 9.2200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.3086
Cell Significance Index: 8.2400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2561
Cell Significance Index: 16.1400 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.2417
Cell Significance Index: 1.9300 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.1367
Cell Significance Index: 15.6000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1012
Cell Significance Index: 190.6400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0950
Cell Significance Index: 69.6300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0586
Cell Significance Index: 37.2000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0285
Cell Significance Index: 3.9100 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0163
Cell Significance Index: -0.8200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0183
Cell Significance Index: -13.5800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0191
Cell Significance Index: -35.2700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0197
Cell Significance Index: -12.2800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0213
Cell Significance Index: -32.8600 - Cell Name: pulmonary alveolar type 2 cell (CL0002063)
Fold Change: -0.0290
Cell Significance Index: -0.2400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0334
Cell Significance Index: -45.3500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0393
Cell Significance Index: -17.8300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0403
Cell Significance Index: -4.1200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0445
Cell Significance Index: -25.1200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0485
Cell Significance Index: -5.5600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0689
Cell Significance Index: -0.9400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0826
Cell Significance Index: -1.7600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.1049
Cell Significance Index: -37.6300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1083
Cell Significance Index: -15.7400 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1153
Cell Significance Index: -3.0300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1165
Cell Significance Index: -33.5200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1190
Cell Significance Index: -25.0600 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1200
Cell Significance Index: -4.9200 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.1686
Cell Significance Index: -2.0100 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.1723
Cell Significance Index: -2.7800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.1841
Cell Significance Index: -36.9400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1987
Cell Significance Index: -23.1600 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: -0.2363
Cell Significance Index: -0.8900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3043
Cell Significance Index: -31.6900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3215
Cell Significance Index: -37.9200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3480
Cell Significance Index: -27.5700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3972
Cell Significance Index: -12.7200 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -0.4092
Cell Significance Index: -5.2700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4506
Cell Significance Index: -27.6300 - Cell Name: peg cell (CL4033014)
Fold Change: -0.4579
Cell Significance Index: -10.5800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4944
Cell Significance Index: -17.1800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.4999
Cell Significance Index: -26.0400 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.5040
Cell Significance Index: -7.0700 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.5358
Cell Significance Index: -5.5500 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: -0.5381
Cell Significance Index: -3.3200 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.5448
Cell Significance Index: -9.4200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.5777
Cell Significance Index: -37.2700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.5900
Cell Significance Index: -39.6700 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.6053
Cell Significance Index: -17.8300 - Cell Name: salivary gland glandular cell (CL1001596)
Fold Change: -0.6324
Cell Significance Index: -3.5200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2576214981
Symbol: SDC4_HUMAN
Name: Amphiglycan
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1500433
Title: Molecular cloning of amphiglycan, a novel integral membrane heparan sulfate proteoglycan expressed by epithelial and fibroblastic cells.
PubMed ID: 1500433
PubMed ID: 7916598
Title: Human ryudocan core protein: molecular cloning and characterization of the cDNA, and chromosomal localization of the gene.
PubMed ID: 7916598
PubMed ID: 8797100
Title: Structural organization and promoter activity of the human ryudocan gene.
PubMed ID: 8797100
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8889549
Title: Generation and analysis of 280,000 human expressed sequence tags.
PubMed ID: 8889549
DOI: 10.1101/gr.6.9.807
PubMed ID: 9169435
Title: Regulated shedding of syndecan-1 and -4 ectodomains by thrombin and growth factor receptor activation.
PubMed ID: 9169435
PubMed ID: 14675776
Title: Widespread production of novel soluble protein isoforms by alternative splicing removal of transmembrane anchoring domains.
PubMed ID: 14675776
PubMed ID: 16007225
Title: Adhesion signaling by a novel mitotic substrate of src kinases.
PubMed ID: 16007225
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22660413
Title: Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.
PubMed ID: 22660413
DOI: 10.1038/ncb2502
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 32337544
Title: An affinity chromatography and glycoproteomics workflow to profile the chondroitin sulfate proteoglycans that interact with malarial VAR2CSA in the placenta and in cancer.
PubMed ID: 32337544
PubMed ID: 36213313
Title: Mass spectrometric analysis of chondroitin sulfate-linked peptides.
PubMed ID: 36213313
PubMed ID: 11456484
Title: Solution structure of the dimeric cytoplasmic domain of syndecan-4.
PubMed ID: 11456484
DOI: 10.1021/bi002750r
PubMed ID: 12842047
Title: Molecular roots of degenerate specificity in syntenin's PDZ2 domain: reassessment of the PDZ recognition paradigm.
PubMed ID: 12842047
PubMed ID: 16533050
Title: The binding of the PDZ tandem of syntenin to target proteins.
PubMed ID: 16533050
DOI: 10.1021/bi052225y
Sequence Information:
- Length: 198
- Mass: 21642
- Checksum: 8229AA2733F77A10
- Sequence:
MAPARLFALL LFFVGGVAES IRETEVIDPQ DLLEGRYFSG ALPDDEDVVG PGQESDDFEL SGSGDLDDLE DSMIGPEVVH PLVPLDNHIP ERAGSGSQVP TEPKKLEENE VIPKRISPVE ESEDVSNKVS MSSTVQGSNI FERTEVLAAL IVGGIVGILF AVFLILLLMY RMKKKDEGSY DLGKKPIYKK APTNEFYA
Genular Protein ID: 540529032
Symbol: B4E1S6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
Sequence Information:
- Length: 126
- Mass: 13910
- Checksum: FFFFA5D3D4B914A4
- Sequence:
MIGPEVVHPL VPLDNHIPER AGSGSQVPTE PKKLEENEVI PKRISPVEES EDVSNKVSMS STVQGSNIFE RTEVLAALIV GGIVGILFAV FLILLLMYRM KKKDEGSYDL GKKPIYKKAP TNEFYA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.