Details for: SEL1L

Gene ID: 6400

Symbol: SEL1L

Ensembl ID: ENSG00000071537

Description: SEL1L adaptor subunit of SYVN1 ubiquitin ligase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 270.9180
    Cell Significance Index: -42.1400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 162.7482
    Cell Significance Index: -41.2800
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 102.5130
    Cell Significance Index: -42.2300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 97.4747
    Cell Significance Index: -46.0200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 94.0537
    Cell Significance Index: -38.2100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 85.4807
    Cell Significance Index: -43.9700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 40.1469
    Cell Significance Index: -38.3300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 34.7377
    Cell Significance Index: -42.8300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 16.5220
    Cell Significance Index: -44.2600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.4669
    Cell Significance Index: -35.2200
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 11.4649
    Cell Significance Index: 188.9300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.9451
    Cell Significance Index: -43.1900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.7042
    Cell Significance Index: -19.0500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 3.1271
    Cell Significance Index: 216.2600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.5390
    Cell Significance Index: 167.4000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3465
    Cell Significance Index: 267.2200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.2772
    Cell Significance Index: 256.2000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.0974
    Cell Significance Index: 18.4900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.0383
    Cell Significance Index: 177.3000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8813
    Cell Significance Index: 158.8700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7487
    Cell Significance Index: 676.0200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7274
    Cell Significance Index: 89.4400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6102
    Cell Significance Index: 218.8700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.5966
    Cell Significance Index: 8.1400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5771
    Cell Significance Index: 79.2500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.5532
    Cell Significance Index: 14.7700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.5357
    Cell Significance Index: 14.3600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4788
    Cell Significance Index: 331.1300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4708
    Cell Significance Index: 10.2000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4510
    Cell Significance Index: 21.0300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4373
    Cell Significance Index: 12.6000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3780
    Cell Significance Index: 206.4100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3713
    Cell Significance Index: 16.8300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3626
    Cell Significance Index: 35.8700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2889
    Cell Significance Index: 22.1700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2870
    Cell Significance Index: 126.8700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.2860
    Cell Significance Index: 19.2300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1969
    Cell Significance Index: 25.2400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1863
    Cell Significance Index: 9.6800
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.1411
    Cell Significance Index: 3.2600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.1404
    Cell Significance Index: 6.2100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1386
    Cell Significance Index: 26.3800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.1337
    Cell Significance Index: 2.6100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.1102
    Cell Significance Index: 3.1600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0923
    Cell Significance Index: 3.5000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0757
    Cell Significance Index: 4.2500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0612
    Cell Significance Index: 115.2200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0551
    Cell Significance Index: 6.2900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0390
    Cell Significance Index: 6.3500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0373
    Cell Significance Index: 1.3100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0172
    Cell Significance Index: 10.9100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0162
    Cell Significance Index: 29.8400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0048
    Cell Significance Index: 7.4400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0029
    Cell Significance Index: 0.0800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0027
    Cell Significance Index: 1.9900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0083
    Cell Significance Index: -11.3300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0115
    Cell Significance Index: -5.2000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0214
    Cell Significance Index: -15.8400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0334
    Cell Significance Index: -20.8600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0372
    Cell Significance Index: -28.1500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0513
    Cell Significance Index: -28.9100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0529
    Cell Significance Index: -7.6900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0604
    Cell Significance Index: -6.1700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0718
    Cell Significance Index: -8.4700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0767
    Cell Significance Index: -5.7200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0918
    Cell Significance Index: -4.3200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1154
    Cell Significance Index: -24.3000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1279
    Cell Significance Index: -36.7900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1362
    Cell Significance Index: -15.8700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1440
    Cell Significance Index: -16.5000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1491
    Cell Significance Index: -9.6200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1606
    Cell Significance Index: -20.7500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1676
    Cell Significance Index: -11.8500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1768
    Cell Significance Index: -9.2100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2114
    Cell Significance Index: -4.6300
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2140
    Cell Significance Index: -1.7500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2377
    Cell Significance Index: -6.1100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2831
    Cell Significance Index: -8.0800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.3320
    Cell Significance Index: -4.9000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3499
    Cell Significance Index: -22.0500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3546
    Cell Significance Index: -9.9100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3743
    Cell Significance Index: -38.9700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3775
    Cell Significance Index: -19.8200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4792
    Cell Significance Index: -2.9000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.4810
    Cell Significance Index: -8.8900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.4876
    Cell Significance Index: -8.1600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4961
    Cell Significance Index: -39.2900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.5286
    Cell Significance Index: -11.3000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.5446
    Cell Significance Index: -5.0200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5636
    Cell Significance Index: -18.0500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.5729
    Cell Significance Index: -14.3200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.6115
    Cell Significance Index: -10.4800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6234
    Cell Significance Index: -38.2200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.6327
    Cell Significance Index: -38.8900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.7426
    Cell Significance Index: -21.8100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.7459
    Cell Significance Index: -25.9200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.7553
    Cell Significance Index: -19.8600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.8745
    Cell Significance Index: -28.6300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.8883
    Cell Significance Index: -28.2900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.8950
    Cell Significance Index: -19.0600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** SEL1L is a crucial component of the SYVN1 ubiquitin ligase, which plays a key role in the ER-associated degradation (ERAD) pathway. This pathway is responsible for the recognition and degradation of misfolded or aberrant proteins within the ER. SEL1L's adaptor function allows it to interact with other components of the SYVN1 complex, facilitating the recognition and ubiquitination of target proteins. The SEL1L gene is also involved in the regulation of lipid metabolism, particularly in the context of triglyceride synthesis and secretion. **Pathways and Functions** SEL1L is involved in several key pathways, including: 1. **ER-associated degradation (ERAD) pathway**: SEL1L's adaptor function allows it to interact with the SYVN1 ubiquitin ligase, facilitating the recognition and degradation of misfolded or aberrant proteins within the ER. 2. **Calnexin/calreticulin cycle**: SEL1L is involved in the regulation of N-glycan trimming and quality control within the ER, ensuring proper protein folding and secretion. 3. **Retrograde protein transport**: SEL1L's interaction with the SYVN1 complex enables the transport of proteins from the ER to the cytosol, facilitating protein secretion and signaling. 4. **Hedgehog ligand biogenesis**: SEL1L's involvement in the regulation of protein quality control and trafficking is also critical for the biogenesis of hedgehog ligands, which play a key role in signaling pathways. **Clinical Significance** Dysregulation of SEL1L has been implicated in several diseases, including: 1. **Cystic fibrosis**: Defective CFTR transport can lead to aberrant ER protein trafficking, resulting in the accumulation of misfolded proteins and contributing to disease pathology. 2. **Pancreatic exocrine disorders**: Alterations in SEL1L expression have been linked to pancreatic exocrine disorders, including pancreatitis and pancreatic cancer. 3. **Neurodegenerative diseases**: SEL1L's involvement in protein quality control and trafficking suggests that dysregulation of this gene may contribute to neurodegenerative diseases, such as Alzheimer's and Parkinson's. In summary, SEL1L plays a critical role in regulating protein quality control and trafficking within the ER, and its dysregulation has been implicated in several diseases. Further research is needed to fully elucidate the mechanisms by which SEL1L contributes to disease pathology and to explore potential therapeutic targets for the treatment of these disorders.

Genular Protein ID: 2127860278

Symbol: SE1L1_HUMAN

Name: Protein sel-1 homolog 1

UniProtKB Accession Codes:

Q9UBV2 Q6UWT6 Q9P1T9 Q9UHK7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 22 Ensembl 2 ExpressionAtlas 1 GO 11 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 6 RefSeq 2 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10496078

Title: Complete cDNA sequence and genomic organization of a human pancreas-specific gene homologous to Caenorhabditis elegans sel-1.

PubMed ID: 10496078

DOI: 10.1007/s100380050171

PubMed ID: 10746565

Title: SEL1L, the human homolog of C. elegans sel-1: refined physical mapping, gene structure and identification of polymorphic markers.

PubMed ID: 10746565

DOI: 10.1007/s004390051032

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 16186509

Title: Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane.

PubMed ID: 16186509

DOI: 10.1073/pnas.0505014102

PubMed ID: 18502753

Title: Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP.

PubMed ID: 18502753

DOI: 10.1074/jbc.m709336200

PubMed ID: 18264092

Title: OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.

PubMed ID: 18264092

DOI: 10.1038/ncb1689

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19524542

Title: EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex.

PubMed ID: 19524542

DOI: 10.1016/j.molcel.2009.05.018

PubMed ID: 19706418

Title: A luminal flavoprotein in endoplasmic reticulum-associated degradation.

PubMed ID: 19706418

DOI: 10.1073/pnas.0900742106

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25066055

Title: The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism.

PubMed ID: 25066055

DOI: 10.1016/j.cmet.2014.06.015

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26471130

Title: Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L.

PubMed ID: 26471130

DOI: 10.1111/febs.13564

PubMed ID: 28827405

Title: Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD).

PubMed ID: 28827405

DOI: 10.1242/jcs.206847

PubMed ID: 29997207

Title: Human Cytomegalovirus Tropism Modulator UL148 Interacts with SEL1L, a Cellular Factor That Governs Endoplasmic Reticulum-Associated Degradation of the Viral Envelope Glycoprotein gO.

PubMed ID: 29997207

DOI: 10.1128/jvi.00688-18

Sequence Information:

  • Length: 794
  • Mass: 88755
  • Checksum: 323EB03DC7485459
  • Sequence:
    • MRVRIGLTLL LCAVLLSLAS ASSDEEGSQD ESLDSKTTLT SDESVKDHTT AGRVVAGQIF 
LDSEESELES SIQEEEDSLK SQEGESVTED ISFLESPNPE NKDYEEPKKV RKPALTAIEG 
TAHGEPCHFP FLFLDKEYDE CTSDGREDGR LWCATTYDYK ADEKWGFCET EEEAAKRRQM 
QEAEMMYQTG MKILNGSNKK SQKREAYRYL QKAASMNHTK ALERVSYALL FGDYLPQNIQ 
AAREMFEKLT EEGSPKGQTA LGFLYASGLG VNSSQAKALV YYTFGALGGN LIAHMVLGYR 
YWAGIGVLQS CESALTHYRL VANHVASDIS LTGGSVVQRI RLPDEVENPG MNSGMLEEDL 
IQYYQFLAEK GDVQAQVGLG QLHLHGGRGV EQNHQRAFDY FNLAANAGNS HAMAFLGKMY 
SEGSDIVPQS NETALHYFKK AADMGNPVGQ SGLGMAYLYG RGVQVNYDLA LKYFQKAAEQ 
GWVDGQLQLG SMYYNGIGVK RDYKQALKYF NLASQGGHIL AFYNLAQMHA SGTGVMRSCH 
TAVELFKNVC ERGRWSERLM TAYNSYKDGD YNAAVIQYLL LAEQGYEVAQ SNAAFILDQR 
EASIVGENET YPRALLHWNR AASQGYTVAR IKLGDYHFYG FGTDVDYETA FIHYRLASEQ 
QHSAQAMFNL GYMHEKGLGI KQDIHLAKRF YDMAAEASPD AQVPVFLALC KLGVVYFLQY 
IRETNIRDMF TQLDMDQLLG PEWDLYLMTI IALLLGTVIA YRQRQHQDMP APRPPGPRPA 
PPQQEGPPEQ QPPQ

Genular Protein ID: 735409917

Symbol: Q3ZCU6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q3ZCU6

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 195
  • Mass: 22239
  • Checksum: 5E61FC72BAEA5471
  • Sequence:
    • SEASIVGENE TYPRALLHWN RAASQGYTVA RIKLGDYHFY GFGTDVDYET AFIHYRLASE 
QQHSAQAMFN LGYMHEKGLG IKQDIHLAKR FYDMAAEASP DAQVPVFLAL CKLGVVYFLQ 
YIRETNIRDM FTQLDMDQLL GPEWDLYLMT IIALLLGTVI AYRQRQHQDM PAPRPPGPRP 
APPQQEGPPE QQPPQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.