Details for: SH3GL1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 177.5689
Cell Significance Index: -27.6200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 119.8139
Cell Significance Index: -30.3900 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 84.6952
Cell Significance Index: -34.8900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 28.6046
Cell Significance Index: -27.3100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 24.9563
Cell Significance Index: -30.7700 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 10.7994
Cell Significance Index: -28.9300 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 8.4260
Cell Significance Index: -25.8800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 7.9700
Cell Significance Index: -31.4500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 7.9458
Cell Significance Index: -17.3900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.8680
Cell Significance Index: 129.1800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.6874
Cell Significance Index: 45.2200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.4277
Cell Significance Index: 141.2400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.2320
Cell Significance Index: 247.1300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.0137
Cell Significance Index: 52.6600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.9627
Cell Significance Index: 191.0500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.9202
Cell Significance Index: 100.0900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.7850
Cell Significance Index: 127.6800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.6315
Cell Significance Index: 17.1900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.6030
Cell Significance Index: 82.8100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.5954
Cell Significance Index: 15.9000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.4790
Cell Significance Index: 331.2600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4640
Cell Significance Index: 13.3700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4237
Cell Significance Index: 231.4200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.4114
Cell Significance Index: 50.5800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.4030
Cell Significance Index: 72.6400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.4001
Cell Significance Index: 11.4700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.3894
Cell Significance Index: 139.6700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3746
Cell Significance Index: 10.4700 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.3700
Cell Significance Index: 47.8100 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.3483
Cell Significance Index: 2.8400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.3234
Cell Significance Index: 15.2000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.3220
Cell Significance Index: 21.6500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.3133
Cell Significance Index: 2.8900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3000
Cell Significance Index: 132.6400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2857
Cell Significance Index: 6.1900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2513
Cell Significance Index: 226.8900 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.1911
Cell Significance Index: 4.0000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1746
Cell Significance Index: 8.1400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1705
Cell Significance Index: 32.4400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1449
Cell Significance Index: 6.5700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.1395
Cell Significance Index: 10.4000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1388
Cell Significance Index: 3.4700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.1118
Cell Significance Index: 3.8900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0824
Cell Significance Index: 6.3300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0591
Cell Significance Index: 111.3600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0502
Cell Significance Index: 8.5800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0502
Cell Significance Index: 77.2400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0477
Cell Significance Index: 30.3200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0469
Cell Significance Index: 3.3200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0373
Cell Significance Index: 4.7800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0351
Cell Significance Index: 64.6900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0025
Cell Significance Index: 3.3400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0207
Cell Significance Index: -9.4100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0238
Cell Significance Index: -17.9800 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.0312
Cell Significance Index: -0.4000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0326
Cell Significance Index: -23.9200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0347
Cell Significance Index: -25.6800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0537
Cell Significance Index: -30.3000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0543
Cell Significance Index: -7.8900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0586
Cell Significance Index: -36.5700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0593
Cell Significance Index: -6.9900 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0843
Cell Significance Index: -1.4100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0888
Cell Significance Index: -9.0700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0949
Cell Significance Index: -27.3000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0995
Cell Significance Index: -2.8400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1086
Cell Significance Index: -12.6600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1290
Cell Significance Index: -8.3200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1540
Cell Significance Index: -3.2800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1708
Cell Significance Index: -35.9800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1724
Cell Significance Index: -19.7500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1858
Cell Significance Index: -11.4200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1948
Cell Significance Index: -6.2400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.1950
Cell Significance Index: -2.6600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1952
Cell Significance Index: -6.8600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2088
Cell Significance Index: -13.1600 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: -0.2109
Cell Significance Index: -1.3100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2195
Cell Significance Index: -9.7100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.2450
Cell Significance Index: -1.4800 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2480
Cell Significance Index: -6.5200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2629
Cell Significance Index: -14.7500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2635
Cell Significance Index: -27.4400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.2759
Cell Significance Index: -7.3800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2910
Cell Significance Index: -11.0200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3074
Cell Significance Index: -16.1400 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.3369
Cell Significance Index: -4.8500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3533
Cell Significance Index: -27.9800 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.3879
Cell Significance Index: -7.5700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.4149
Cell Significance Index: -7.1100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4401
Cell Significance Index: -26.9800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.4493
Cell Significance Index: -11.5500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.5020
Cell Significance Index: -26.1500 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.5232
Cell Significance Index: -8.8000 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.5266
Cell Significance Index: -9.3100 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.5959
Cell Significance Index: -17.5000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.5991
Cell Significance Index: -12.8100 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.6193
Cell Significance Index: -13.5600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6462
Cell Significance Index: -20.5800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.6486
Cell Significance Index: -21.2400 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.6531
Cell Significance Index: -7.1000 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.6531
Cell Significance Index: -33.0100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1805448839
Symbol: SH3G1_HUMAN
Name: Endophilin-A2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9169142
Title: A novel SH3-containing human gene family preferentially expressed in the central nervous system.
PubMed ID: 9169142
PubMed ID: 9122235
Title: EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia.
PubMed ID: 9122235
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10542231
Title: The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity.
PubMed ID: 10542231
PubMed ID: 17350572
Title: Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding.
PubMed ID: 17350572
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23285027
Title: Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis.
PubMed ID: 23285027
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 368
- Mass: 41490
- Checksum: 6E5BE978BC955077
- Sequence:
MSVAGLKKQF YKASQLVSEK VGGAEGTKLD DDFKEMEKKV DVTSKAVTEV LARTIEYLQP NPASRAKLTM LNTVSKIRGQ VKNPGYPQSE GLLGECMIRH GKELGGESNF GDALLDAGES MKRLAEVKDS LDIEVKQNFI DPLQNLCEKD LKEIQHHLKK LEGRRLDFDY KKKRQGKIPD EELRQALEKF EESKEVAETS MHNLLETDIE QVSQLSALVD AQLDYHRQAV QILDELAEKL KRRMREASSR PKREYKPKPR EPFDLGEPEQ SNGGFPCTTA PKIAASSSFR SSDKPIRTPS RSMPPLDQPS CKALYDFEPE NDGELGFHEG DVITLTNQID ENWYEGMLDG QSGFFPLSYV EVLVPLPQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.