Details for: STXBP2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 138.3520
Cell Significance Index: -21.5200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 87.5639
Cell Significance Index: -22.2100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 61.6605
Cell Significance Index: -25.0500 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 58.9465
Cell Significance Index: -27.8300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 53.4230
Cell Significance Index: -27.4800 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 41.4889
Cell Significance Index: -27.8400 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 26.7192
Cell Significance Index: -25.5100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 19.9034
Cell Significance Index: -24.5400 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 7.1756
Cell Significance Index: 132.6300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 7.0501
Cell Significance Index: -27.8200 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 5.9320
Cell Significance Index: -18.2200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 5.2112
Cell Significance Index: -13.9600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 3.8909
Cell Significance Index: 453.4400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 3.2453
Cell Significance Index: 224.4300 - Cell Name: precursor cell (CL0011115)
Fold Change: 2.8617
Cell Significance Index: 21.7000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 2.1316
Cell Significance Index: 57.0200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.5636
Cell Significance Index: 93.8700 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 1.4701
Cell Significance Index: 43.1800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.3861
Cell Significance Index: 64.6300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.3058
Cell Significance Index: 129.1700 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.2086
Cell Significance Index: 11.1300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.9137
Cell Significance Index: 24.8700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.8455
Cell Significance Index: 54.5500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.7074
Cell Significance Index: 52.7200 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.6828
Cell Significance Index: 4.5300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.6748
Cell Significance Index: 121.6400 - Cell Name: epidermal cell (CL0000362)
Fold Change: 0.6742
Cell Significance Index: 1.5200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.6683
Cell Significance Index: 31.4100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.6518
Cell Significance Index: 33.8600 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.6066
Cell Significance Index: 9.0900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5720
Cell Significance Index: 70.3400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.5687
Cell Significance Index: 310.5800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.4344
Cell Significance Index: 51.2300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.4051
Cell Significance Index: 11.3200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3825
Cell Significance Index: 345.4100 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.3566
Cell Significance Index: 46.0800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3498
Cell Significance Index: 56.8900 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.3275
Cell Significance Index: 2.6200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3205
Cell Significance Index: 9.2400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.3101
Cell Significance Index: 8.2800 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.3091
Cell Significance Index: 3.2000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2664
Cell Significance Index: 6.6600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2292
Cell Significance Index: 101.3500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2169
Cell Significance Index: 4.7000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.2133
Cell Significance Index: 5.7200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1793
Cell Significance Index: 34.1200 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 0.1625
Cell Significance Index: 1.0000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0966
Cell Significance Index: 6.8300 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.0579
Cell Significance Index: 0.3600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0563
Cell Significance Index: 1.9800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0452
Cell Significance Index: 34.2200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0269
Cell Significance Index: 4.5900 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.0011
Cell Significance Index: 0.1100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0002
Cell Significance Index: -0.0300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0088
Cell Significance Index: -0.4000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0123
Cell Significance Index: -23.1900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0160
Cell Significance Index: -11.7000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0253
Cell Significance Index: -46.6000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0313
Cell Significance Index: -23.1600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0313
Cell Significance Index: -48.1100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0336
Cell Significance Index: -21.3400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0361
Cell Significance Index: -49.0400 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0405
Cell Significance Index: -1.0700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0458
Cell Significance Index: -25.8500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0492
Cell Significance Index: -30.7000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0545
Cell Significance Index: -15.6700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0547
Cell Significance Index: -19.6100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0686
Cell Significance Index: -31.1300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0712
Cell Significance Index: -14.2900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0751
Cell Significance Index: -3.8000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1083
Cell Significance Index: -12.4100 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1127
Cell Significance Index: -2.8800 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1200
Cell Significance Index: -4.9200 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1536
Cell Significance Index: -19.6900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1561
Cell Significance Index: -32.8800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1582
Cell Significance Index: -23.0000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1615
Cell Significance Index: -22.1800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.2047
Cell Significance Index: -4.3600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2622
Cell Significance Index: -27.3100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2622
Cell Significance Index: -6.7400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2719
Cell Significance Index: -8.7100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2938
Cell Significance Index: -23.2700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.3174
Cell Significance Index: -4.3300 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.3477
Cell Significance Index: -4.9400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.3622
Cell Significance Index: -18.8700 - Cell Name: peg cell (CL4033014)
Fold Change: -0.3688
Cell Significance Index: -8.5200 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3713
Cell Significance Index: -10.9400 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.3872
Cell Significance Index: -7.5700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.3872
Cell Significance Index: -29.7200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3938
Cell Significance Index: -24.8200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.4179
Cell Significance Index: -28.1000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4294
Cell Significance Index: -14.9200 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.4432
Cell Significance Index: -7.6400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4513
Cell Significance Index: -27.6700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4573
Cell Significance Index: -28.1100 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.4600
Cell Significance Index: -4.7600 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.5035
Cell Significance Index: -5.7200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.5268
Cell Significance Index: -29.5600 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.5604
Cell Significance Index: -4.5700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.5790
Cell Significance Index: -25.6100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2460131438
Symbol: STXB2_HUMAN
Name: Syntaxin-binding protein 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8921365
Title: Molecular characterization of a nonneuronal human UNC18 homolog.
PubMed ID: 8921365
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19804848
Title: Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11.
PubMed ID: 19804848
PubMed ID: 19884660
Title: Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells.
PubMed ID: 19884660
DOI: 10.1172/jci40732
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 593
- Mass: 66453
- Checksum: 98E27B55309168A9
- Sequence:
MAPSGLKAVV GEKILSGVIR SVKKDGEWKV LIMDHPSMRI LSSCCKMSDI LAEGITIVED INKRREPIPS LEAIYLLSPT EKSVQALIKD FQGTPTFTYK AAHIFFTDTC PEPLFSELGR SRLAKVVKTL KEIHLAFLPY EAQVFSLDAP HSTYNLYCPF RAEERTRQLE VLAQQIATLC ATLQEYPAIR YRKGPEDTAQ LAHAVLAKLN AFKADTPSLG EGPEKTRSQL LIMDRAADPV SPLLHELTFQ AMAYDLLDIE QDTYRYETTG LSEAREKAVL LDEDDDLWVE LRHMHIADVS KKVTELLRTF CESKRLTTDK ANIKDLSQIL KKMPQYQKEL NKYSTHLHLA DDCMKHFKGS VEKLCSVEQD LAMGSDAEGE KIKDSMKLIV PVLLDAAVPA YDKIRVLLLY ILLRNGVSEE NLAKLIQHAN VQAHSSLIRN LEQLGGTVTN PGGSGTSSRL EPRERMEPTY QLSRWTPVIK DVMEDAVEDR LDRNLWPFVS DPAPTASSQA AVSARFGHWH KNKAGIEARA GPRLIVYVMG GVAMSEMRAA YEVTRATEGK WEVLIGSSHI LTPTRFLDDL KALDKKLEDI ALP
Genular Protein ID: 1170956516
Symbol: Q53GF4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8125298
Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
PubMed ID: 8125298
PubMed ID: 9373149
Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
PubMed ID: 9373149
Sequence Information:
- Length: 593
- Mass: 66366
- Checksum: 5BE27B47B2021A2B
- Sequence:
MAPSGLKAVV GEKILSGVIR SVKKDGEWKV LIMDHPSMRI LSSCCKMSDI LAEGITIVED INKRREPIPS LEAIYLLSPT EKSVQALIKD FQGTPTFTYK AAHIFFTDTC PEPLFSELGR SRLAKVVKTL KEIHLAFLPY EAQVFSLDAP HSTYNLYCPF RAEERTRQLE VLAQQIATLC ATLQEYPAIR YRKGPEDTAQ LAHAVLAKLN AFKADTPSLG EGPEKTRSQL LIMDRAADPV SPLLHELTFQ AMAYDLLDIE QDTYRYETTG LSEAREKAVL LDEDDDLWVE LRHMHIADVS KKVTELLRTF CESKRLTTDK ANIKDLSQIL KKMPQYQKEL NKYSTHLHLA DDCMKHFKGS VEKLCSVEQD LAMGSDAEGE KIKDSMKLIV PVLLDAAVPA YDKIRVLLLY ILLRNGVSEE NLAKLIQHAN VQAHSSLIRN LEQLGGTVTN PGGSGTSSRL EPRERMEPTY QLSRWTPVIK DVMEDAVEDR LDRNLWPFVS DPAPTASSQA AVSARFGHWH KNKAGVEARA GPRLIVYVMG GVAMSEMRAA YEVTRATEGK WEVLIGSSHI LTPTRFLDDL KALDKKLGDI ALP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.