Details for: TIE1

Gene ID: 7075

Symbol: TIE1

Ensembl ID: ENSG00000066056

Description: tyrosine kinase with immunoglobulin like and EGF like domains 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 61.0755
    Cell Significance Index: -9.5000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 34.2213
    Cell Significance Index: -8.6800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 21.6119
    Cell Significance Index: -8.7800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 9.5052
    Cell Significance Index: -9.0800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 7.6970
    Cell Significance Index: -9.4900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.1227
    Cell Significance Index: -13.4000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 5.2486
    Cell Significance Index: 273.3900
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 5.1752
    Cell Significance Index: 30.5600
  • Cell Name: glomerular capillary endothelial cell (CL1001005)
    Fold Change: 2.6268
    Cell Significance Index: 9.7900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.4430
    Cell Significance Index: -9.6400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 2.2166
    Cell Significance Index: 31.8800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.8100
    Cell Significance Index: 31.9900
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 1.7778
    Cell Significance Index: 6.1900
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 1.6110
    Cell Significance Index: 11.5700
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.2234
    Cell Significance Index: 7.6600
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 1.0511
    Cell Significance Index: 4.5200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.9744
    Cell Significance Index: 11.0700
  • Cell Name: endothelial stalk cell (CL0002671)
    Fold Change: 0.6595
    Cell Significance Index: 7.3900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.5379
    Cell Significance Index: 3.2500
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.4858
    Cell Significance Index: 3.8400
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.4603
    Cell Significance Index: 6.4600
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 0.4208
    Cell Significance Index: 3.0900
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.3887
    Cell Significance Index: 3.7000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3618
    Cell Significance Index: 35.7900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.2896
    Cell Significance Index: 4.4800
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.1385
    Cell Significance Index: 1.4400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0044
    Cell Significance Index: 3.0600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0032
    Cell Significance Index: -1.9900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0036
    Cell Significance Index: -2.6300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0042
    Cell Significance Index: -7.8800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0054
    Cell Significance Index: -1.0800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0056
    Cell Significance Index: -3.1600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0067
    Cell Significance Index: -12.4400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0081
    Cell Significance Index: -12.4400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0093
    Cell Significance Index: -12.6600
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: -0.0112
    Cell Significance Index: -0.0900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0119
    Cell Significance Index: -2.3800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0136
    Cell Significance Index: -9.9600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0142
    Cell Significance Index: -10.7400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0150
    Cell Significance Index: -9.5000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0158
    Cell Significance Index: -3.3200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0194
    Cell Significance Index: -10.5700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0225
    Cell Significance Index: -3.8400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0231
    Cell Significance Index: -10.4900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0255
    Cell Significance Index: -4.5900
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.0256
    Cell Significance Index: -0.3500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0262
    Cell Significance Index: -9.3800
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0277
    Cell Significance Index: -0.3400
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0291
    Cell Significance Index: -0.4000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0292
    Cell Significance Index: -8.4100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0436
    Cell Significance Index: -5.0800
  • Cell Name: gut endothelial cell (CL0000131)
    Fold Change: -0.0451
    Cell Significance Index: -0.3100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0505
    Cell Significance Index: -6.2200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0508
    Cell Significance Index: -2.2100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0541
    Cell Significance Index: -6.9300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0626
    Cell Significance Index: -7.1500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0627
    Cell Significance Index: -9.1200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0628
    Cell Significance Index: -1.6800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0683
    Cell Significance Index: -9.3800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0739
    Cell Significance Index: -9.5500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0817
    Cell Significance Index: -6.2700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0846
    Cell Significance Index: -8.6400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0917
    Cell Significance Index: -10.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0947
    Cell Significance Index: -9.8600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0973
    Cell Significance Index: -6.2800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0976
    Cell Significance Index: -11.1800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1258
    Cell Significance Index: -9.9600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1322
    Cell Significance Index: -8.3300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1354
    Cell Significance Index: -10.0900
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: -0.1459
    Cell Significance Index: -1.5900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1529
    Cell Significance Index: -10.2800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1611
    Cell Significance Index: -9.9000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1745
    Cell Significance Index: -10.7000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1875
    Cell Significance Index: -9.4700
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.1879
    Cell Significance Index: -1.9800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1950
    Cell Significance Index: -10.9400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1989
    Cell Significance Index: -9.3500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2011
    Cell Significance Index: -10.5600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2126
    Cell Significance Index: -5.4300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2157
    Cell Significance Index: -5.7800
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.2236
    Cell Significance Index: -4.5500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2312
    Cell Significance Index: -10.4800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2316
    Cell Significance Index: -12.0300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2344
    Cell Significance Index: -10.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2364
    Cell Significance Index: -11.0200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2463
    Cell Significance Index: -8.6300
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.2711
    Cell Significance Index: -3.0800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2733
    Cell Significance Index: -10.3500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2797
    Cell Significance Index: -9.7200
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.2848
    Cell Significance Index: -3.6800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2857
    Cell Significance Index: -9.3600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2873
    Cell Significance Index: -9.1500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.2894
    Cell Significance Index: -7.0100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2926
    Cell Significance Index: -10.7400
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.2938
    Cell Significance Index: -3.1900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3119
    Cell Significance Index: -8.9400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3202
    Cell Significance Index: -9.4300
  • Cell Name: vein endothelial cell of respiratory system (CL4033008)
    Fold Change: -0.3416
    Cell Significance Index: -2.2000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3419
    Cell Significance Index: -9.1300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.3475
    Cell Significance Index: -12.2100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** TIE1 is a type I transmembrane receptor tyrosine kinase, characterized by the presence of immunoglobulin-like and EGF-like domains. Its unique structure allows it to interact with various ligands, including vascular endothelial growth factor (VEGF), which is a key player in angiogenesis. TIE1 is expressed in a wide range of cell types, including endothelial cells, mesenchymal cells, and immune cells, highlighting its broad functional scope. **Pathways and Functions:** TIE1 is integral to several signaling pathways that regulate endothelial cell behavior, including: 1. **Angiogenesis:** TIE1, in conjunction with its ligand VEGF, promotes angiogenesis by regulating endothelial cell migration, proliferation, and tube formation. 2. **Endothelial Cell Differentiation:** TIE1 is essential for the differentiation of endothelial progenitor cells into mature endothelial cells, a process critical for vascular development and maintenance. 3. **Tissue Remodeling:** TIE1 is involved in the regulation of extracellular matrix assembly and degradation, allowing for tissue remodeling in response to injury or disease. 4. **Immune Response:** TIE1 has been implicated in the regulation of immune cell function, including the activation of T cells and the production of cytokines. **Clinical Significance:** Dysregulation of TIE1 has been linked to various diseases, including: 1. **Cancer:** TIE1 overexpression has been observed in several types of cancer, including breast, lung, and colon cancer, where it promotes angiogenesis and tumor growth. 2. **Cardiovascular Disease:** TIE1 is involved in the regulation of vascular remodeling and atherosclerosis, highlighting its potential as a therapeutic target for cardiovascular disease. 3. **Autoimmune Disorders:** TIE1 has been implicated in the regulation of immune cell function, making it a potential target for the treatment of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In conclusion, TIE1 is a complex gene that plays a multifaceted role in the regulation of angiogenesis, endothelial cell differentiation, and tissue remodeling. Its dysregulation has significant implications for human disease, highlighting the need for further research into the molecular mechanisms underlying TIE1 function and its role in disease.

Genular Protein ID: 754637412

Symbol: TIE1_HUMAN

Name: Tyrosine-protein kinase receptor Tie-1

UniProtKB Accession Codes:

P35590 B5A949 B5A950

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 ChEBI 7 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 2 EMBL 6 Ensembl 1 GO 20 Gene3D 3 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 14 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRINTS 1 PRO 1 PROSITE 7 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 RefSeq 1 Rhea 3 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 1312667

Title: A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains.

PubMed ID: 1312667

DOI: 10.1128/mcb.12.4.1698-1707.1992

PubMed ID: 18593464

Title: Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.

PubMed ID: 18593464

DOI: 10.1186/ar2447

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 15851516

Title: Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2.

PubMed ID: 15851516

DOI: 10.1083/jcb.200411105

PubMed ID: 20227369

Title: Tie1-Tie2 interactions mediate functional differences between angiopoietin ligands.

PubMed ID: 20227369

DOI: 10.1016/j.molcel.2010.02.007

PubMed ID: 37097004

Title: Svep1 is a binding ligand of Tie1 and affects specific aspects of facial lymphatic development in a Vegfc-independent manner.

PubMed ID: 37097004

DOI: 10.7554/elife.82969

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

PubMed ID: 32947856

Title: TIE1 as a Candidate Gene for Lymphatic Malformations with or without Lymphedema.

PubMed ID: 32947856

DOI: 10.3390/ijms21186780

Sequence Information:

  • Length: 1138
  • Mass: 125090
  • Checksum: 3B42BE33678C58A1
  • Sequence:
    • MVWRVPPFLL PILFLASHVG AAVDLTLLAN LRLTDPQRFF LTCVSGEAGA GRGSDAWGPP 
LLLEKDDRIV RTPPGPPLRL ARNGSHQVTL RGFSKPSDLV GVFSCVGGAG ARRTRVIYVH 
NSPGAHLLPD KVTHTVNKGD TAVLSARVHK EKQTDVIWKS NGSYFYTLDW HEAQDGRFLL 
QLPNVQPPSS GIYSATYLEA SPLGSAFFRL IVRGCGAGRW GPGCTKECPG CLHGGVCHDH 
DGECVCPPGF TGTRCEQACR EGRFGQSCQE QCPGISGCRG LTFCLPDPYG CSCGSGWRGS 
QCQEACAPGH FGADCRLQCQ CQNGGTCDRF SGCVCPSGWH GVHCEKSDRI PQILNMASEL 
EFNLETMPRI NCAAAGNPFP VRGSIELRKP DGTVLLSTKA IVEPEKTTAE FEVPRLVLAD 
SGFWECRVST SGGQDSRRFK VNVKVPPVPL AAPRLLTKQS RQLVVSPLVS FSGDGPISTV 
RLHYRPQDST MDWSTIVVDP SENVTLMNLR PKTGYSVRVQ LSRPGEGGEG AWGPPTLMTT 
DCPEPLLQPW LEGWHVEGTD RLRVSWSLPL VPGPLVGDGF LLRLWDGTRG QERRENVSSP 
QARTALLTGL TPGTHYQLDV QLYHCTLLGP ASPPAHVLLP PSGPPAPRHL HAQALSDSEI 
QLTWKHPEAL PGPISKYVVE VQVAGGAGDP LWIDVDRPEE TSTIIRGLNA STRYLFRMRA 
SIQGLGDWSN TVEESTLGNG LQAEGPVQES RAAEEGLDQQ LILAVVGSVS ATCLTILAAL 
LTLVCIRRSC LHRRRTFTYQ SGSGEETILQ FSSGTLTLTR RPKLQPEPLS YPVLEWEDIT 
FEDLIGEGNF GQVIRAMIKK DGLKMNAAIK MLKEYASEND HRDFAGELEV LCKLGHHPNI 
INLLGACKNR GYLYIAIEYA PYGNLLDFLR KSRVLETDPA FAREHGTAST LSSRQLLRFA 
SDAANGMQYL SEKQFIHRDL AARNVLVGEN LASKIADFGL SRGEEVYVKK TMGRLPVRWM 
AIESLNYSVY TTKSDVWSFG VLLWEIVSLG GTPYCGMTCA ELYEKLPQGY RMEQPRNCDD 
EVYELMRQCW RDRPYERPPF AQIALQLGRM LEARKAYVNM SLFENFTYAG IDATAEEA

Genular Protein ID: 724238906

Symbol: B4DTW8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DTW8

Database IDs:

ARBA 14 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 6 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 6 Gene3D 3 InterPro 14 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 10 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 3 RefSeq 1 Rhea 3 SAM 1 SMART 4 SMR 1 SUPFAM 3

Sequence Information:

  • Length: 1093
  • Mass: 120186
  • Checksum: 73614F6A97FD3E2B
  • Sequence:
    • MWAGAGRGSD AWGPPLLLEK DDRIVRTPPG PPLRLARNGS HQVTLRGFSK PSDLVGVFSC 
VGGAGARRTR VIYVHNSPGA HLLPDKVTHT VNKGDTAVLS ARVHKEKQTD VIWKSNGSYF 
YTLDWHEAQD GRFLLQLPNV QPPSSGIYSA TYLEASPLGS AFFRLIVRGC GAGRWGPGCT 
KECPGCLHGG VCHDHDGECV CPPGFTGTRC EQACREGRFG QSCQEQCPGI SGCRGLTFCL 
PDPYGCSCGS GWRGSQCQEA CAPGHFGADC RLQCQCQNGG TCDRFSGCVC PSGWHGVHCE 
KSDRIPQILN MASELEFNLE TMPRINCAAA GNPFPVRGSI ELRKPDGTVL LSTKAIVEPE 
KTTAEFEVPR LVLADSGFWE CRVSTSGGQD SRRFKVNVKV PPVPLAAPRL LTKQSRQLVV 
SPLVSFSGDG PISTVRLHYR PQDSTMDWST IVVDPSENVT LMNLRPKTGY SVRVQLSRPG 
EGGEGAWGPP TLMTTDCPEP LLQPWLEGWH VEGTDRLRVS WSLPLVPGPL VGDGFLLRLW 
DGTRGQERRE NVSSPQARTA LLTGLTPGTH YQLDVQLYHC TLLGPASPPA HVLLPPSGPP 
APRHLHAQAL SDSEIQLTWK HPEALPGPIS KYVVEVQVAG GAGDPLWIDV DRPEETSTII 
RGLNASTRYL FRMRASIQGL GDWSNTVEES TLGNGLQAEG PVQESRAAEE GLDQQLILAV 
VGSVSATCLT ILAALLTLVC IRRSCLHRRR TFTYQSGSGE ETILQFSSGT LTLTRRPKLQ 
PEPLSYPVLE WEDITFEDLI GEGNFGQVIR AMIKKDGLKM NAAIKMLKEY ASENDHRDFA 
GELEVLCKLG HHPNIINLLG ACKNRGYLYI AIEYAPYGNL LDFLRKSRVL ETDPAFAREH 
GTASTLSSRQ LLRFASDAAN GMQYLSEKQF IHRDLAARNV LVGENLASKI ADFGLSRGEE 
VYVKKTMGRL PVRWMAIESL NYSVYTTKSD VWSFGVLLWE IVSLGGTPYC GMTCAELYEK 
LPQGYRMEQP RNCDDEVYEL MRQCWRDRPY ERPPFAQIAL QLGRMLEARK AYVNMSLFEN 
FTYAGIDATA EEA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.