Details for: TLE4

Gene ID: 7091

Symbol: TLE4

Ensembl ID: ENSG00000106829

Description: TLE family member 4, transcriptional corepressor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 452.7944
    Cell Significance Index: -70.4300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 261.1935
    Cell Significance Index: -66.2500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 154.9386
    Cell Significance Index: -73.1500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 150.7420
    Cell Significance Index: -61.2400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 135.2294
    Cell Significance Index: -69.5600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 109.2363
    Cell Significance Index: -73.3000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 64.6247
    Cell Significance Index: -61.7000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 58.0556
    Cell Significance Index: -71.5800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 25.2719
    Cell Significance Index: -67.7000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 20.0752
    Cell Significance Index: -61.6600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 18.3196
    Cell Significance Index: -72.2900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 14.0661
    Cell Significance Index: -30.7900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 4.8818
    Cell Significance Index: 273.9400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 4.2898
    Cell Significance Index: 223.4500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 4.0124
    Cell Significance Index: 47.8300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.7927
    Cell Significance Index: 167.7600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.4127
    Cell Significance Index: 129.2300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.9171
    Cell Significance Index: 474.4400
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 2.6707
    Cell Significance Index: 27.8200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.1969
    Cell Significance Index: 99.5800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.0289
    Cell Significance Index: 130.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.9841
    Cell Significance Index: 357.6700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.8992
    Cell Significance Index: 260.8100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.6804
    Cell Significance Index: 48.1700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.6514
    Cell Significance Index: 203.0500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.5197
    Cell Significance Index: 52.8100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.3513
    Cell Significance Index: 146.9800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.3286
    Cell Significance Index: 587.3900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.2099
    Cell Significance Index: 31.1000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.1551
    Cell Significance Index: 32.2800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0616
    Cell Significance Index: 212.9500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.9975
    Cell Significance Index: 127.8800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.9503
    Cell Significance Index: 27.3800
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.9111
    Cell Significance Index: 22.2300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.8064
    Cell Significance Index: 17.4700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7695
    Cell Significance Index: 152.7100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.6226
    Cell Significance Index: 29.2600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.5865
    Cell Significance Index: 1104.2900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5852
    Cell Significance Index: 30.4000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.5457
    Cell Significance Index: 28.6500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5083
    Cell Significance Index: 277.6000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4471
    Cell Significance Index: 309.2200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.4351
    Cell Significance Index: 6.5200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.3691
    Cell Significance Index: 12.9700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3407
    Cell Significance Index: 33.7000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.2970
    Cell Significance Index: 19.9700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2944
    Cell Significance Index: 18.5600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2524
    Cell Significance Index: 6.3100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1532
    Cell Significance Index: 282.5800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1292
    Cell Significance Index: 46.3500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1132
    Cell Significance Index: 174.2400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1015
    Cell Significance Index: 19.3200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0804
    Cell Significance Index: 10.3900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0677
    Cell Significance Index: 1.1600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0372
    Cell Significance Index: 4.3900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0294
    Cell Significance Index: 39.9100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0220
    Cell Significance Index: 9.9700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0142
    Cell Significance Index: 0.3800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0111
    Cell Significance Index: -0.8600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0261
    Cell Significance Index: -16.6000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0378
    Cell Significance Index: -2.6700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0471
    Cell Significance Index: -6.8500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0692
    Cell Significance Index: -52.4000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0716
    Cell Significance Index: -52.5200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0968
    Cell Significance Index: -71.6700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1144
    Cell Significance Index: -3.0700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1291
    Cell Significance Index: -80.6000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1301
    Cell Significance Index: -73.3600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1514
    Cell Significance Index: -3.9800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1600
    Cell Significance Index: -7.4600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1981
    Cell Significance Index: -33.8200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2150
    Cell Significance Index: -61.8500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3298
    Cell Significance Index: -4.5000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3531
    Cell Significance Index: -5.9100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3786
    Cell Significance Index: -79.7400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.3833
    Cell Significance Index: -3.5300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3843
    Cell Significance Index: -10.4600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4113
    Cell Significance Index: -2.4900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.4117
    Cell Significance Index: -47.9800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4408
    Cell Significance Index: -45.9000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.4465
    Cell Significance Index: -45.6100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.5240
    Cell Significance Index: -32.2100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5709
    Cell Significance Index: -65.4100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7462
    Cell Significance Index: -24.4300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.7494
    Cell Significance Index: -13.8500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7846
    Cell Significance Index: -25.1300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7914
    Cell Significance Index: -25.2100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.8248
    Cell Significance Index: -61.4800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8249
    Cell Significance Index: -65.3300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.8358
    Cell Significance Index: -17.8000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.8757
    Cell Significance Index: -6.7500
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.9972
    Cell Significance Index: -14.3200
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -1.1209
    Cell Significance Index: -11.3100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1512
    Cell Significance Index: -70.5800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.1830
    Cell Significance Index: -33.7600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -1.2247
    Cell Significance Index: -25.6400
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.2299
    Cell Significance Index: -30.6800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.3361
    Cell Significance Index: -35.7400
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.4967
    Cell Significance Index: -18.8900
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -1.5125
    Cell Significance Index: -23.0100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Transcriptional Corepressor Activity:** TLE4 acts as a transcriptional corepressor, inhibiting the transcription of target genes by interacting with transcriptional activators and co-repressors. 2. **Wnt Signaling Pathway Regulation:** TLE4 is a negative regulator of the Wnt signaling pathway, which is involved in cell proliferation, differentiation, and survival. 3. **Cellular Expression:** TLE4 is expressed in various cell types, including skeletal muscle satellite stem cells, lung endothelial cells, and oligodendrocytes. 4. **Chromatin Binding:** TLE4 binds to chromatin, facilitating the recruitment of co-repressors and transcriptional inhibitors. **Pathways and Functions:** 1. **Beta-catenin-Tcf Complex:** TLE4 interacts with the beta-catenin-Tcf complex, a key regulator of Wnt signaling pathway. 2. **Deactivation of Beta-catenin Transactivating Complex:** TLE4 deactivates the beta-catenin transactivating complex, inhibiting Wnt signaling pathway activation. 3. **Degradation of Beta-catenin by the Destruction Complex:** TLE4 is involved in the degradation of beta-catenin by the destruction complex, further inhibiting Wnt signaling pathway activation. 4. **Negative Regulation of Canonical Wnt Signaling Pathway:** TLE4 negatively regulates the canonical Wnt signaling pathway, which is involved in cell proliferation, differentiation, and survival. 5. **Repression of Wnt Target Genes:** TLE4 represses the expression of Wnt target genes, which are involved in various cellular processes, including cell proliferation and differentiation. **Clinical Significance:** 1. **Cancer:** TLE4 has been implicated in various types of cancer, including breast, lung, and colon cancer, where it is involved in the regulation of Wnt signaling pathway. 2. **Neurological Disorders:** TLE4 has been associated with neurological disorders, including Alzheimer's disease and Parkinson's disease, where it is involved in the regulation of Wnt signaling pathway. 3. **Wnt Signaling Pathway Dysregulation:** TLE4's role in regulating Wnt signaling pathway dysregulation has been implicated in various diseases, including cancer and neurological disorders. 4. **Therapeutic Targeting:** TLE4's involvement in the Wnt signaling pathway makes it a potential therapeutic target for the treatment of various diseases, including cancer and neurological disorders. In conclusion, TLE4 is a transcriptional corepressor that plays a crucial role in regulating the Wnt signaling pathway. Its involvement in various cellular processes, including cell proliferation, differentiation, and survival, makes it an important gene in understanding the regulation of cellular processes. Further research on TLE4's role in various diseases will provide insights into the development of novel therapeutic strategies.

Genular Protein ID: 2702481656

Symbol: TLE4_HUMAN

Name: Transducin-like enhancer protein 4

UniProtKB Accession Codes:

Q04727 F8W6T6 Q3ZCS1 Q5T1Y2 Q6PCB3 Q9BZ07 Q9BZ08 Q9BZ09 Q9NSL3 Q9ULF9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 4 ExpressionAtlas 1 GO 11 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 4 RefSeq 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10574462

Title: Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10574462

DOI: 10.1093/dnares/6.5.337

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 1303260

Title: Human homologs of a Drosophila enhancer of split gene product define a novel family of nuclear proteins.

PubMed ID: 1303260

DOI: 10.1038/ng1092-119

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18254933

Title: The Groucho/TLE/Grg family of transcriptional co-repressors.

PubMed ID: 18254933

DOI: 10.1186/gb-2008-9-1-205

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21429299

Title: EphrinB1 interacts with the transcriptional co-repressor Groucho/xTLE4.

PubMed ID: 21429299

DOI: 10.5483/bmbrep.2011.44.3.199

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22304967

Title: XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling.

PubMed ID: 22304967

DOI: 10.1016/j.molcel.2011.12.032

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24676634

Title: Mutations in PAX2 associate with adult-onset FSGS.

PubMed ID: 24676634

DOI: 10.1681/asn.2013070686

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 773
  • Mass: 83755
  • Checksum: DA138F1DA29E81B6
  • Sequence:
    • MIRDLSKMYP QTRHPAPHQP AQPFKFTISE SCDRIKEEFQ FLQAQYHSLK LECEKLASEK 
TEMQRHYVMY YEMSYGLNIE MHKQAEIVKR LNAICAQVIP FLSQEHQQQV VQAVERAKQV 
TMAELNAIIG QQLQAQHLSH GHGLPVPLTP HPSGLQPPAI PPIGSSAGLL ALSSALGGQS 
HLPIKDEKKH HDNDHQRDRD SIKSSSVSPS ASFRGAEKHR NSADYSSESK KQKTEEKEIA 
ARYDSDGEKS DDNLVVDVSN EDPSSPRGSP AHSPRENGLD KTRLLKKDAP ISPASIASSS 
STPSSKSKEL SLNEKSTTPV SKSNTPTPRT DAPTPGSNST PGLRPVPGKP PGVDPLASSL 
RTPMAVPCPY PTPFGIVPHA GMNGELTSPG AAYAGLHNIS PQMSAAAAAA AAAAAYGRSP 
VVGFDPHHHM RVPAIPPNLT GIPGGKPAYS FHVSADGQMQ PVPFPPDALI GPGIPRHARQ 
INTLNHGEVV CAVTISNPTR HVYTGGKGCV KVWDISHPGN KSPVSQLDCL NRDNYIRSCR 
LLPDGRTLIV GGEASTLSIW DLAAPTPRIK AELTSSAPAC YALAISPDSK VCFSCCSDGN 
IAVWDLHNQT LVRQFQGHTD GASCIDISND GTKLWTGGLD NTVRSWDLRE GRQLQQHDFT 
SQIFSLGYCP TGEWLAVGME NSNVEVLHVT KPDKYQLHLH ESCVLSLKFA HCGKWFVSTG 
KDNLLNAWRT PYGASIFQSK ESSSVLSCDI SVDDKYIVTG SGDKKATVYE VIY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.