Details for: VARS1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 86.9843
Cell Significance Index: -13.5300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 56.8416
Cell Significance Index: -14.4200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 39.9378
Cell Significance Index: -16.2300 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 30.1108
Cell Significance Index: -20.2100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 17.2402
Cell Significance Index: -16.4600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 13.3014
Cell Significance Index: -16.4000 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 9.9308
Cell Significance Index: 247.6500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.3170
Cell Significance Index: -17.0400 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 2.9563
Cell Significance Index: -9.0800 - Cell Name: decidual cell (CL2000002)
Fold Change: 2.3486
Cell Significance Index: 37.6800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.2252
Cell Significance Index: -4.8700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.9516
Cell Significance Index: 134.9600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.2209
Cell Significance Index: 132.8000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.0681
Cell Significance Index: 173.7200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.9396
Cell Significance Index: 12.8200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.7354
Cell Significance Index: 38.2000 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.5593
Cell Significance Index: 7.8500 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.5225
Cell Significance Index: 5.6800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5014
Cell Significance Index: 14.4500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4782
Cell Significance Index: 10.3600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.4057
Cell Significance Index: 26.1800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.3816
Cell Significance Index: 75.7300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3594
Cell Significance Index: 16.2900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3221
Cell Significance Index: 175.9100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.3165
Cell Significance Index: 63.4900 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.3126
Cell Significance Index: 4.7100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3011
Cell Significance Index: 57.3100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.2902
Cell Significance Index: 8.1100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2360
Cell Significance Index: 42.5400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2251
Cell Significance Index: 22.2700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.2209
Cell Significance Index: 15.6200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2116
Cell Significance Index: 93.5800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.2056
Cell Significance Index: 35.1000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2003
Cell Significance Index: 138.5500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.1937
Cell Significance Index: 4.0600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1857
Cell Significance Index: 8.6600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1599
Cell Significance Index: 10.0800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1461
Cell Significance Index: 20.0700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1402
Cell Significance Index: 6.5900 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.1401
Cell Significance Index: 18.1000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1359
Cell Significance Index: 48.7600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1329
Cell Significance Index: 16.3400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.1324
Cell Significance Index: 4.2400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.1110
Cell Significance Index: 5.7800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.0683
Cell Significance Index: 61.6300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0585
Cell Significance Index: 2.0600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0446
Cell Significance Index: 0.9500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0437
Cell Significance Index: 3.2600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0435
Cell Significance Index: 5.5800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0381
Cell Significance Index: 4.4900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0342
Cell Significance Index: 3.9200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.0123
Cell Significance Index: 0.3300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0024
Cell Significance Index: 4.6100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0013
Cell Significance Index: 0.0400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0010
Cell Significance Index: -0.7900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0014
Cell Significance Index: -0.0700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0048
Cell Significance Index: -8.7700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0049
Cell Significance Index: -0.1300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0095
Cell Significance Index: -14.6600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0105
Cell Significance Index: -6.6400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0123
Cell Significance Index: -16.7500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0131
Cell Significance Index: -9.5700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0181
Cell Significance Index: -13.4300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0265
Cell Significance Index: -0.9200 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.0268
Cell Significance Index: -0.1800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0295
Cell Significance Index: -16.6300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0312
Cell Significance Index: -14.1800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0319
Cell Significance Index: -4.6300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0375
Cell Significance Index: -23.4200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0390
Cell Significance Index: -3.9800 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: -0.0508
Cell Significance Index: -0.5300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0568
Cell Significance Index: -1.4500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0623
Cell Significance Index: -17.9200 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.0687
Cell Significance Index: -0.7800 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.0776
Cell Significance Index: -0.7200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0822
Cell Significance Index: -1.3800 - Cell Name: peg cell (CL4033014)
Fold Change: -0.0961
Cell Significance Index: -2.2200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1024
Cell Significance Index: -21.5600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1050
Cell Significance Index: -2.7600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1085
Cell Significance Index: -3.1100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1139
Cell Significance Index: -6.3900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1157
Cell Significance Index: -8.8800 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1313
Cell Significance Index: -3.8600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1532
Cell Significance Index: -15.9600 - Cell Name: epidermal cell (CL0000362)
Fold Change: -0.1641
Cell Significance Index: -0.3700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1653
Cell Significance Index: -4.2500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1770
Cell Significance Index: -10.8500 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1804
Cell Significance Index: -7.3900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1977
Cell Significance Index: -10.3800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.2040
Cell Significance Index: -5.1000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2080
Cell Significance Index: -16.4700 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.2321
Cell Significance Index: -1.9500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2581
Cell Significance Index: -11.4200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2914
Cell Significance Index: -10.2100 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.2937
Cell Significance Index: -4.6600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3001
Cell Significance Index: -8.8400 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.3028
Cell Significance Index: -3.6100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.3053
Cell Significance Index: -11.5600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3185
Cell Significance Index: -10.1400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3386
Cell Significance Index: -11.0900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1156530065
Symbol: SYVC_HUMAN
Name: Protein G7a
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1898367
Title: Evidence that gene G7a in the human major histocompatibility complex encodes valyl-tRNA synthetase.
PubMed ID: 1898367
DOI: 10.1042/bj2780809
PubMed ID: 14656967
Title: Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.
PubMed ID: 14656967
DOI: 10.1101/gr.1736803
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8428657
Title: Cloning, sequencing and expression of a cDNA encoding mammalian valyl-tRNA synthetase.
PubMed ID: 8428657
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 26539891
Title: Genes that affect brain structure and function identified by rare variant analyses of mendelian neurologic disease.
PubMed ID: 26539891
Sequence Information:
- Length: 1264
- Mass: 140476
- Checksum: 95CCDDBB3AB148AD
- Sequence:
MSTLYVSPHP DAFPSLRALI AARYGEAGEG PGWGGAHPRI CLQPPPTSRT PFPPPRLPAL EQGPGGLWVW GATAVAQLLW PAGLGGPGGS RAAVLVQQWV SYADTELIPA ACGATLPALG LRSSAQDPQA VLGALGRALS PLEEWLRLHT YLAGEAPTLA DLAAVTALLL PFRYVLDPPA RRIWNNVTRW FVTCVRQPEF RAVLGEVVLY SGARPLSHQP GPEAPALPKT AAQLKKEAKK REKLEKFQQK QKIQQQQPPP GEKKPKPEKR EKRDPGVITY DLPTPPGEKK DVSGPMPDSY SPRYVEAAWY PWWEQQGFFK PEYGRPNVSA ANPRGVFMMC IPPPNVTGSL HLGHALTNAI QDSLTRWHRM RGETTLWNPG CDHAGIATQV VVEKKLWREQ GLSRHQLGRE AFLQEVWKWK EEKGDRIYHQ LKKLGSSLDW DRACFTMDPK LSAAVTEAFV RLHEEGIIYR STRLVNWSCT LNSAISDIEV DKKELTGRTL LSVPGYKEKV EFGVLVSFAY KVQGSDSDEE VVVATTRIET MLGDVAVAVH PKDTRYQHLK GKNVIHPFLS RSLPIVFDEF VDMDFGTGAV KITPAHDQND YEVGQRHGLE AISIMDSRGA LINVPPPFLG LPRFEARKAV LVALKERGLF RGIEDNPMVV PLCNRSKDVV EPLLRPQWYV RCGEMAQAAS AAVTRGDLRI LPEAHQRTWH AWMDNIREWC ISRQLWWGHR IPAYFVTVSD PAVPPGEDPD GRYWVSGRNE AEAREKAAKE FGVSPDKISL QQDEDVLDTW FSSGLFPLSI LGWPNQSEDL SVFYPGTLLE TGHDILFFWV ARMVMLGLKL TGRLPFREVY LHAIVRDAHG RKMSKSLGNV IDPLDVIYGI SLQGLHNQLL NSNLDPSEVE KAKEGQKADF PAGIPECGTD ALRFGLCAYM SQGRDINLDV NRILGYRHFC NKLWNATKFA LRGLGKGFVP SPTSQPGGHE SLVDRWIRSR LTEAVRLSNQ GFQAYDFPAV TTAQYSFWLY ELCDVYLECL KPVLNGVDQV AAECARQTLY TCLDVGLRLL SPFMPFVTEE LFQRLPRRMP QAPPSLCVTP YPEPSECSWK DPEAEAALEL ALSITRAVRS LRADYNLTRI RPDCFLEVAD EATGALASAV SGYVQALASA GVVAVLALGA PAPQGCAVAL ASDRCSIHLQ LQGLVDPARE LGKLQAKRVE AQRQAQRLRE RRAASGYPVK VPLEVQEADE AKLQQTEAEL RKVDEAIALF QKML
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.