Details for: VEGFA

Gene ID: 7422

Symbol: VEGFA

Ensembl ID: ENSG00000112715

Description: vascular endothelial growth factor A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 328.4254
    Cell Significance Index: -51.0900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 206.6287
    Cell Significance Index: -52.4100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 122.6127
    Cell Significance Index: -50.5100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 111.8989
    Cell Significance Index: -52.8300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 106.5089
    Cell Significance Index: -43.2700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 78.8648
    Cell Significance Index: -52.9200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 45.4468
    Cell Significance Index: -43.3900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 42.2765
    Cell Significance Index: -52.1300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 19.7584
    Cell Significance Index: -52.9300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.2335
    Cell Significance Index: -52.2200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 7.6578
    Cell Significance Index: 104.4800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.8712
    Cell Significance Index: 110.9700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.9943
    Cell Significance Index: 135.7200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.7378
    Cell Significance Index: 142.2200
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 2.5597
    Cell Significance Index: 19.7300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.3768
    Cell Significance Index: 68.4800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.7090
    Cell Significance Index: 131.1500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 1.6525
    Cell Significance Index: 40.3200
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 1.4564
    Cell Significance Index: 6.3400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.3890
    Cell Significance Index: 250.4000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.3840
    Cell Significance Index: 37.0900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.3299
    Cell Significance Index: 36.2000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.2962
    Cell Significance Index: 21.8400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1045
    Cell Significance Index: 997.2600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.0941
    Cell Significance Index: 134.5400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.0569
    Cell Significance Index: 114.9600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9011
    Cell Significance Index: 492.1100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8897
    Cell Significance Index: 53.4100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8332
    Cell Significance Index: 165.3600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4463
    Cell Significance Index: 20.9800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3564
    Cell Significance Index: 35.2600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3476
    Cell Significance Index: 16.2100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.3356
    Cell Significance Index: 38.3100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2864
    Cell Significance Index: 440.8300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.2831
    Cell Significance Index: 4.1800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2520
    Cell Significance Index: 6.3000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2278
    Cell Significance Index: 5.9900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2177
    Cell Significance Index: 37.1700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.2067
    Cell Significance Index: 10.8500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1915
    Cell Significance Index: 260.3700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1778
    Cell Significance Index: 334.7900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.1575
    Cell Significance Index: 1.4500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1488
    Cell Significance Index: 102.9400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1469
    Cell Significance Index: 270.9100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1279
    Cell Significance Index: 16.3900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0995
    Cell Significance Index: 13.6600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0955
    Cell Significance Index: 19.1500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0748
    Cell Significance Index: 33.0800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0491
    Cell Significance Index: 22.2800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0066
    Cell Significance Index: 4.2000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0002
    Cell Significance Index: 0.1800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0136
    Cell Significance Index: -0.2000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0147
    Cell Significance Index: -11.1500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.0161
    Cell Significance Index: -3.0600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0190
    Cell Significance Index: -14.0700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0192
    Cell Significance Index: -0.9700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0213
    Cell Significance Index: -0.5900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0225
    Cell Significance Index: -0.4800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0262
    Cell Significance Index: -2.6800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0299
    Cell Significance Index: -18.6800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0376
    Cell Significance Index: -1.9600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0395
    Cell Significance Index: -14.1600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0628
    Cell Significance Index: -35.4300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0640
    Cell Significance Index: -2.2500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0715
    Cell Significance Index: -5.0600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1053
    Cell Significance Index: -22.1800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1284
    Cell Significance Index: -14.7100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1319
    Cell Significance Index: -19.1700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1399
    Cell Significance Index: -40.2600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1838
    Cell Significance Index: -13.7000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1840
    Cell Significance Index: -23.7700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2041
    Cell Significance Index: -5.4500
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.2113
    Cell Significance Index: -3.4100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2309
    Cell Significance Index: -4.9400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3026
    Cell Significance Index: -35.2700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3140
    Cell Significance Index: -32.7000
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.3476
    Cell Significance Index: -1.6100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3535
    Cell Significance Index: -22.2800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3764
    Cell Significance Index: -21.1200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3785
    Cell Significance Index: -6.3400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.4182
    Cell Significance Index: -9.0600
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.4315
    Cell Significance Index: -4.4700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.4445
    Cell Significance Index: -52.4200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4686
    Cell Significance Index: -28.8000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5064
    Cell Significance Index: -16.2200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5607
    Cell Significance Index: -44.4100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.5851
    Cell Significance Index: -8.4200
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.5857
    Cell Significance Index: -8.9100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.5979
    Cell Significance Index: -11.6700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6314
    Cell Significance Index: -38.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.6683
    Cell Significance Index: -43.1200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.7347
    Cell Significance Index: -49.4000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.7990
    Cell Significance Index: -29.3300
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.8223
    Cell Significance Index: -6.7100
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.8888
    Cell Significance Index: -5.4700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.8897
    Cell Significance Index: -39.3600
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.9843
    Cell Significance Index: -16.9100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.9924
    Cell Significance Index: -25.5100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.0334
    Cell Significance Index: -19.1000
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.0481
    Cell Significance Index: -13.0700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** * VEGFA is a dimeric protein composed of two identical subunits * It binds to two receptors: VEGF receptor 1 (VEGFR1) and VEGF receptor 2 (VEGFR2) * The VEGFA-VEGFR2 pathway is a critical regulator of angiogenesis * VEGFA is involved in various signaling pathways, including the PI3K/Akt and MAPK/ERK pathways * It has been shown to regulate cell migration, proliferation, and differentiation in various cell types * VEGFA is highly expressed in response to hypoxia, a condition characterized by low oxygen levels **Pathways and Functions** VEGFA plays a central role in the regulation of angiogenesis through the VEGFA-VEGFR2 pathway. This pathway involves the binding of VEGFA to VEGFR2, leading to receptor dimerization and the activation of downstream signaling cascades. These cascades ultimately regulate cell migration, proliferation, and differentiation, contributing to the formation of new blood vessels. VEGFA is also involved in other signaling pathways, including the PI3K/Akt and MAPK/ERK pathways, which regulate cell survival, metabolism, and differentiation. In addition to its role in angiogenesis, VEGFA has been shown to regulate various cellular processes, including: * Cell migration and invasion * Cell proliferation and differentiation * Gene expression and transcription * Metabolism and energy production * Apoptosis and cell death **Clinical Significance** VEGFA has been implicated in various diseases and disorders, including: * Cancer: VEGFA is overexpressed in many types of cancer, including breast, lung, and colon cancer, and is associated with tumor growth, metastasis, and poor prognosis. * Cardiovascular disease: VEGFA is involved in the development of atherosclerosis and other cardiovascular diseases, and has been shown to regulate blood vessel formation and remodeling. * Neurological disorders: VEGFA has been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's and Parkinson's disease. * Wound healing: VEGFA plays a key role in the regulation of wound healing, and its dysregulation has been associated with delayed wound healing and impaired tissue regeneration. In summary, VEGFA is a critical regulator of angiogenesis and various cellular processes, and its dysregulation has been implicated in various diseases and disorders. Further research on the role of VEGFA in human disease is necessary to fully understand its clinical significance and to develop effective therapeutic strategies.

Genular Protein ID: 2529866018

Symbol: VEGFA_HUMAN

Name: Vascular endothelial growth factor A, long form

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2479986

Title: Vascular endothelial growth factor is a secreted angiogenic mitogen.

PubMed ID: 2479986

DOI: 10.1126/science.2479986

PubMed ID: 2479987

Title: Vascular permeability factor, an endothelial cell mitogen related to PDGF.

PubMed ID: 2479987

DOI: 10.1126/science.2479987

PubMed ID: 1711045

Title: The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing.

PubMed ID: 1711045

DOI: 10.1016/s0021-9258(18)99049-6

PubMed ID: 1791831

Title: The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA.

PubMed ID: 1791831

DOI: 10.1210/mend-5-12-1806

PubMed ID: 1567395

Title: AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor.

PubMed ID: 1567395

DOI: 10.1016/s0006-291x(05)80313-4

PubMed ID: 9054410

Title: VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix.

PubMed ID: 9054410

DOI: 10.1074/jbc.272.11.7151

PubMed ID: 9878851

Title: Identification and characterization of a new splicing variant of vascular endothelial growth factor: VEGF183.

PubMed ID: 9878851

DOI: 10.1016/s0167-4781(98)00240-1

PubMed ID: 9450968

Title: Identification of a human VPF/VEGF 3' untranslated region mediating hypoxia-induced mRNA stability.

PubMed ID: 9450968

DOI: 10.1091/mbc.9.2.469

PubMed ID: 10464055

Title: Heterogeneous vascular endothelial growth factor (VEGF) isoform mRNA and receptor mRNA expression in human glomeruli, and the identification of VEGF148 mRNA, a novel truncated splice variant.

PubMed ID: 10464055

DOI: 10.1042/cs0970303

PubMed ID: 12124351

Title: VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma.

PubMed ID: 12124351

PubMed ID: 19054851

Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.

PubMed ID: 19054851

DOI: 10.1038/nmeth.1273

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7678805

Title: Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells.

PubMed ID: 7678805

DOI: 10.1111/j.1432-1033.1993.tb19865.x

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 2584205

Title: Human vascular permeability factor. Isolation from U937 cells.

PubMed ID: 2584205

DOI: 10.1016/s0021-9258(19)47212-8

PubMed ID: 10067980

Title: Human Muller cells express VEGF183, a novel spliced variant of vascular endothelial growth factor.

PubMed ID: 10067980

PubMed ID: 11563986

Title: A precursor form of vascular endothelial growth factor arises by initiation from an upstream in-frame CUG codon.

PubMed ID: 11563986

DOI: 10.1042/0264-6021:3590219

PubMed ID: 11427521

Title: Vascular endothelial growth factor induces cyclooxygenase-dependent proliferation of endothelial cells via the VEGF-2 receptor.

PubMed ID: 11427521

DOI: 10.1096/fj.00-0757fje

PubMed ID: 11731620

Title: New vascular endothelial growth factor isoform generated by internal ribosome entry site-driven CUG translation initiation.

PubMed ID: 11731620

DOI: 10.1210/mend.15.12.0738

PubMed ID: 11978667

Title: A common polymorphism in the 5'-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes.

PubMed ID: 11978667

DOI: 10.2337/diabetes.51.5.1635

PubMed ID: 15520188

Title: VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression.

PubMed ID: 15520188

DOI: 10.1158/0008-5472.can-04-0934

PubMed ID: 14764596

Title: Control of the vascular endothelial growth factor internal ribosome entry site (IRES) activity and translation initiation by alternatively spliced coding sequences.

PubMed ID: 14764596

DOI: 10.1074/jbc.m308410200

PubMed ID: 15896327

Title: Nuclear localization of long-VEGF is associated with hypoxia and tumor angiogenesis.

PubMed ID: 15896327

DOI: 10.1016/j.bbrc.2005.04.123

PubMed ID: 16489009

Title: Minimal active domain and mechanism of action of the angiogenesis inhibitor histidine-rich glycoprotein.

PubMed ID: 16489009

DOI: 10.1158/0008-5472.can-05-2217

PubMed ID: 17446437

Title: Association of ATP1A1 and dear single-nucleotide polymorphism haplotypes with essential hypertension: sex-specific and haplotype-specific effects.

PubMed ID: 17446437

DOI: 10.1161/01.res.0000267716.96196.60

PubMed ID: 22009797

Title: RSUME is implicated in HIF-1-induced VEGF-A production in pituitary tumour cells.

PubMed ID: 22009797

DOI: 10.1530/erc-11-0211

PubMed ID: 26503042

Title: CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.

PubMed ID: 26503042

DOI: 10.1038/nature15510

PubMed ID: 26789244

Title: Corrigendum: CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.

PubMed ID: 26789244

DOI: 10.1038/nature16499

PubMed ID: 25825981

Title: EMMPRIN/CD147 is a novel coreceptor of VEGFR-2 mediating its activation by VEGF.

PubMed ID: 25825981

DOI: 10.18632/oncotarget.2870

PubMed ID: 34530889

Title: KAI1(CD82) is a key molecule to control angiogenesis and switch angiogenic milieu to quiescent state.

PubMed ID: 34530889

DOI: 10.1186/s13045-021-01147-6

PubMed ID: 35455969

Title: N-VEGF, the Autoregulatory Arm of VEGF-A.

PubMed ID: 35455969

DOI: 10.3390/cells11081289

PubMed ID: 9207067

Title: Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site.

PubMed ID: 9207067

DOI: 10.1073/pnas.94.14.7192

PubMed ID: 9336848

Title: 1H, 13C, and 15N backbone assignment and secondary structure of the receptor-binding domain of vascular endothelial growth factor.

PubMed ID: 9336848

DOI: 10.1002/pro.5560061020

PubMed ID: 9351807

Title: The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93-A resolution: multiple copy flexibility and receptor binding.

PubMed ID: 9351807

DOI: 10.1016/s0969-2126(97)00284-0

PubMed ID: 9922142

Title: Crystal structure of the complex between VEGF and a receptor-blocking peptide.

PubMed ID: 9922142

DOI: 10.1021/bi9819327

PubMed ID: 9634701

Title: Solution structure of the heparin-binding domain of vascular endothelial growth factor.

PubMed ID: 9634701

DOI: 10.1016/s0969-2126(98)00065-3

Sequence Information:

  • Length: 395
  • Mass: 43597
  • Checksum: 8ADF6524B1835A2D
  • Sequence:
  • MTDRQTDTAP SPSYHLLPGR RRTVDAAASR GQGPEPAPGG GVEGVGARGV ALKLFVQLLG 
    CSRFGGAVVR AGEAEPSGAA RSASSGREEP QPEEGEEEEE KEEERGPQWR LGARKPGSWT 
    GEAAVCADSA PAARAPQALA RASGRGGRVA RRGAEESGPP HSPSRRGSAS RAGPGRASET 
    MNFLLSWVHW SLALLLYLHH AKWSQAAPMA EGGGQNHHEV VKFMDVYQRS YCHPIETLVD 
    IFQEYPDEIE YIFKPSCVPL MRCGGCCNDE GLECVPTEES NITMQIMRIK PHQGQHIGEM 
    SFLQHNKCEC RPKKDRARQE KKSVRGKGKG QKRKRKKSRY KSWSVPCGPC SERRKHLFVQ 
    DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR

Genular Protein ID: 1147774985

Symbol: A0A0Y0IMM4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 191
  • Mass: 22314
  • Checksum: CCE57097DD3779BD
  • Sequence:
  • MNFLLSWVHW SLALLLYLHH AKWSQAAPMA EGGGQNHHEV VKFMDVYQRS YCHPIETLVD 
    IFQEYPDEIE YIFKPSCVPL MRCGGCCNDE GLECVPTEES NITMQIMRIK PHQGQHIGEM 
    SFLQHNKCEC RPKKDRARQE NPCGPCSERR KHLFVQDPQT CKCSCKNTDS RCKARQLELN 
    ERTCRCDKPR R

Genular Protein ID: 2594596350

Symbol: A2A2V4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 163
  • Mass: 18998
  • Checksum: EBEE0C8E00457A2E
  • Sequence:
  • MAEGGGQNHH EVVKFMDVYQ RSYCHPIETL VDIFQEYPDE IEYIFKPSCV PLMRCGGCCN 
    DEGLECVPTE ESNITMQIMR IKPHQGQHIG EMSFLQHNKC ECRPKKDRAR QENPCGPCSE 
    RRKHLFVQDP QTCKCSCKNT DSRCKARQLE LNERTCRCDK PRR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.