Details for: VEGFA
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 328.4254
Cell Significance Index: -51.0900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 206.6287
Cell Significance Index: -52.4100 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 122.6127
Cell Significance Index: -50.5100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 111.8989
Cell Significance Index: -52.8300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 106.5089
Cell Significance Index: -43.2700 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 78.8648
Cell Significance Index: -52.9200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 45.4468
Cell Significance Index: -43.3900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 42.2765
Cell Significance Index: -52.1300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 19.7584
Cell Significance Index: -52.9300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 13.2335
Cell Significance Index: -52.2200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 7.6578
Cell Significance Index: 104.4800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 3.8712
Cell Significance Index: 110.9700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 2.9943
Cell Significance Index: 135.7200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.7378
Cell Significance Index: 142.2200 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 2.5597
Cell Significance Index: 19.7300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 2.3768
Cell Significance Index: 68.4800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.7090
Cell Significance Index: 131.1500 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 1.6525
Cell Significance Index: 40.3200 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: 1.4564
Cell Significance Index: 6.3400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.3890
Cell Significance Index: 250.4000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.3840
Cell Significance Index: 37.0900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.3299
Cell Significance Index: 36.2000 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.2962
Cell Significance Index: 21.8400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.1045
Cell Significance Index: 997.2600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.0941
Cell Significance Index: 134.5400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.0569
Cell Significance Index: 114.9600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.9011
Cell Significance Index: 492.1100 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.8897
Cell Significance Index: 53.4100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.8332
Cell Significance Index: 165.3600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4463
Cell Significance Index: 20.9800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3564
Cell Significance Index: 35.2600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.3476
Cell Significance Index: 16.2100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.3356
Cell Significance Index: 38.3100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2864
Cell Significance Index: 440.8300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.2831
Cell Significance Index: 4.1800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2520
Cell Significance Index: 6.3000 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.2278
Cell Significance Index: 5.9900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.2177
Cell Significance Index: 37.1700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.2067
Cell Significance Index: 10.8500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1915
Cell Significance Index: 260.3700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1778
Cell Significance Index: 334.7900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.1575
Cell Significance Index: 1.4500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1488
Cell Significance Index: 102.9400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1469
Cell Significance Index: 270.9100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1279
Cell Significance Index: 16.3900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0995
Cell Significance Index: 13.6600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0955
Cell Significance Index: 19.1500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0748
Cell Significance Index: 33.0800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0491
Cell Significance Index: 22.2800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0066
Cell Significance Index: 4.2000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0002
Cell Significance Index: 0.1800 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.0136
Cell Significance Index: -0.2000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0147
Cell Significance Index: -11.1500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.0161
Cell Significance Index: -3.0600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0190
Cell Significance Index: -14.0700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0192
Cell Significance Index: -0.9700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0213
Cell Significance Index: -0.5900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0225
Cell Significance Index: -0.4800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0262
Cell Significance Index: -2.6800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0299
Cell Significance Index: -18.6800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0376
Cell Significance Index: -1.9600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0395
Cell Significance Index: -14.1600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0628
Cell Significance Index: -35.4300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0640
Cell Significance Index: -2.2500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0715
Cell Significance Index: -5.0600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1053
Cell Significance Index: -22.1800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1284
Cell Significance Index: -14.7100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1319
Cell Significance Index: -19.1700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1399
Cell Significance Index: -40.2600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1838
Cell Significance Index: -13.7000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1840
Cell Significance Index: -23.7700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2041
Cell Significance Index: -5.4500 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.2113
Cell Significance Index: -3.4100 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.2309
Cell Significance Index: -4.9400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3026
Cell Significance Index: -35.2700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3140
Cell Significance Index: -32.7000 - Cell Name: perivascular cell (CL4033054)
Fold Change: -0.3476
Cell Significance Index: -1.6100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3535
Cell Significance Index: -22.2800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3764
Cell Significance Index: -21.1200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3785
Cell Significance Index: -6.3400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.4182
Cell Significance Index: -9.0600 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.4315
Cell Significance Index: -4.4700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.4445
Cell Significance Index: -52.4200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4686
Cell Significance Index: -28.8000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5064
Cell Significance Index: -16.2200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5607
Cell Significance Index: -44.4100 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.5851
Cell Significance Index: -8.4200 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.5857
Cell Significance Index: -8.9100 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.5979
Cell Significance Index: -11.6700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.6314
Cell Significance Index: -38.7100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.6683
Cell Significance Index: -43.1200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.7347
Cell Significance Index: -49.4000 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.7990
Cell Significance Index: -29.3300 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.8223
Cell Significance Index: -6.7100 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.8888
Cell Significance Index: -5.4700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.8897
Cell Significance Index: -39.3600 - Cell Name: monocyte-derived dendritic cell (CL0011031)
Fold Change: -0.9843
Cell Significance Index: -16.9100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.9924
Cell Significance Index: -25.5100 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -1.0334
Cell Significance Index: -19.1000 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -1.0481
Cell Significance Index: -13.0700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2529866018
Symbol: VEGFA_HUMAN
Name: Vascular endothelial growth factor A, long form
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2479986
Title: Vascular endothelial growth factor is a secreted angiogenic mitogen.
PubMed ID: 2479986
PubMed ID: 2479987
Title: Vascular permeability factor, an endothelial cell mitogen related to PDGF.
PubMed ID: 2479987
PubMed ID: 1711045
Title: The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing.
PubMed ID: 1711045
PubMed ID: 1791831
Title: The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA.
PubMed ID: 1791831
PubMed ID: 1567395
Title: AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor.
PubMed ID: 1567395
PubMed ID: 9054410
Title: VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix.
PubMed ID: 9054410
PubMed ID: 9878851
Title: Identification and characterization of a new splicing variant of vascular endothelial growth factor: VEGF183.
PubMed ID: 9878851
PubMed ID: 9450968
Title: Identification of a human VPF/VEGF 3' untranslated region mediating hypoxia-induced mRNA stability.
PubMed ID: 9450968
DOI: 10.1091/mbc.9.2.469
PubMed ID: 10464055
Title: Heterogeneous vascular endothelial growth factor (VEGF) isoform mRNA and receptor mRNA expression in human glomeruli, and the identification of VEGF148 mRNA, a novel truncated splice variant.
PubMed ID: 10464055
DOI: 10.1042/cs0970303
PubMed ID: 12124351
Title: VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma.
PubMed ID: 12124351
PubMed ID: 19054851
Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.
PubMed ID: 19054851
DOI: 10.1038/nmeth.1273
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7678805
Title: Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells.
PubMed ID: 7678805
PubMed ID: 15340161
Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.
PubMed ID: 15340161
DOI: 10.1110/ps.04682504
PubMed ID: 2584205
Title: Human vascular permeability factor. Isolation from U937 cells.
PubMed ID: 2584205
PubMed ID: 10067980
Title: Human Muller cells express VEGF183, a novel spliced variant of vascular endothelial growth factor.
PubMed ID: 10067980
PubMed ID: 11563986
Title: A precursor form of vascular endothelial growth factor arises by initiation from an upstream in-frame CUG codon.
PubMed ID: 11563986
PubMed ID: 11427521
Title: Vascular endothelial growth factor induces cyclooxygenase-dependent proliferation of endothelial cells via the VEGF-2 receptor.
PubMed ID: 11427521
PubMed ID: 11731620
Title: New vascular endothelial growth factor isoform generated by internal ribosome entry site-driven CUG translation initiation.
PubMed ID: 11731620
PubMed ID: 11978667
Title: A common polymorphism in the 5'-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes.
PubMed ID: 11978667
PubMed ID: 15520188
Title: VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression.
PubMed ID: 15520188
PubMed ID: 14764596
Title: Control of the vascular endothelial growth factor internal ribosome entry site (IRES) activity and translation initiation by alternatively spliced coding sequences.
PubMed ID: 14764596
PubMed ID: 15896327
Title: Nuclear localization of long-VEGF is associated with hypoxia and tumor angiogenesis.
PubMed ID: 15896327
PubMed ID: 16489009
Title: Minimal active domain and mechanism of action of the angiogenesis inhibitor histidine-rich glycoprotein.
PubMed ID: 16489009
PubMed ID: 17446437
Title: Association of ATP1A1 and dear single-nucleotide polymorphism haplotypes with essential hypertension: sex-specific and haplotype-specific effects.
PubMed ID: 17446437
PubMed ID: 22009797
Title: RSUME is implicated in HIF-1-induced VEGF-A production in pituitary tumour cells.
PubMed ID: 22009797
DOI: 10.1530/erc-11-0211
PubMed ID: 26503042
Title: CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.
PubMed ID: 26503042
DOI: 10.1038/nature15510
PubMed ID: 26789244
Title: Corrigendum: CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.
PubMed ID: 26789244
DOI: 10.1038/nature16499
PubMed ID: 25825981
Title: EMMPRIN/CD147 is a novel coreceptor of VEGFR-2 mediating its activation by VEGF.
PubMed ID: 25825981
PubMed ID: 34530889
Title: KAI1(CD82) is a key molecule to control angiogenesis and switch angiogenic milieu to quiescent state.
PubMed ID: 34530889
PubMed ID: 35455969
PubMed ID: 9207067
Title: Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site.
PubMed ID: 9207067
PubMed ID: 9336848
Title: 1H, 13C, and 15N backbone assignment and secondary structure of the receptor-binding domain of vascular endothelial growth factor.
PubMed ID: 9336848
PubMed ID: 9351807
Title: The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93-A resolution: multiple copy flexibility and receptor binding.
PubMed ID: 9351807
PubMed ID: 9922142
Title: Crystal structure of the complex between VEGF and a receptor-blocking peptide.
PubMed ID: 9922142
DOI: 10.1021/bi9819327
PubMed ID: 9634701
Title: Solution structure of the heparin-binding domain of vascular endothelial growth factor.
PubMed ID: 9634701
Sequence Information:
- Length: 395
- Mass: 43597
- Checksum: 8ADF6524B1835A2D
- Sequence:
MTDRQTDTAP SPSYHLLPGR RRTVDAAASR GQGPEPAPGG GVEGVGARGV ALKLFVQLLG CSRFGGAVVR AGEAEPSGAA RSASSGREEP QPEEGEEEEE KEEERGPQWR LGARKPGSWT GEAAVCADSA PAARAPQALA RASGRGGRVA RRGAEESGPP HSPSRRGSAS RAGPGRASET MNFLLSWVHW SLALLLYLHH AKWSQAAPMA EGGGQNHHEV VKFMDVYQRS YCHPIETLVD IFQEYPDEIE YIFKPSCVPL MRCGGCCNDE GLECVPTEES NITMQIMRIK PHQGQHIGEM SFLQHNKCEC RPKKDRARQE KKSVRGKGKG QKRKRKKSRY KSWSVPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Genular Protein ID: 1147774985
Symbol: A0A0Y0IMM4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 191
- Mass: 22314
- Checksum: CCE57097DD3779BD
- Sequence:
MNFLLSWVHW SLALLLYLHH AKWSQAAPMA EGGGQNHHEV VKFMDVYQRS YCHPIETLVD IFQEYPDEIE YIFKPSCVPL MRCGGCCNDE GLECVPTEES NITMQIMRIK PHQGQHIGEM SFLQHNKCEC RPKKDRARQE NPCGPCSERR KHLFVQDPQT CKCSCKNTDS RCKARQLELN ERTCRCDKPR R
Genular Protein ID: 2594596350
Symbol: A2A2V4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 163
- Mass: 18998
- Checksum: EBEE0C8E00457A2E
- Sequence:
MAEGGGQNHH EVVKFMDVYQ RSYCHPIETL VDIFQEYPDE IEYIFKPSCV PLMRCGGCCN DEGLECVPTE ESNITMQIMR IKPHQGQHIG EMSFLQHNKC ECRPKKDRAR QENPCGPCSE RRKHLFVQDP QTCKCSCKNT DSRCKARQLE LNERTCRCDK PRR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.