Details for: WIPF1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 239.3195
Cell Significance Index: -37.2300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 123.7959
Cell Significance Index: -31.4000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 102.0536
Cell Significance Index: -41.4600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 90.5485
Cell Significance Index: -42.7500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 88.7273
Cell Significance Index: -45.6400 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 44.5774
Cell Significance Index: -42.5600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 30.2160
Cell Significance Index: -37.2600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 15.5443
Cell Significance Index: -34.0200 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 13.3292
Cell Significance Index: -40.9400 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 11.0363
Cell Significance Index: 29.5700 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 10.3066
Cell Significance Index: -27.6100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.6958
Cell Significance Index: -38.2600 - Cell Name: centroblast (CL0009112)
Fold Change: 3.7376
Cell Significance Index: 8.7200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 2.8380
Cell Significance Index: 83.3500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.5379
Cell Significance Index: 299.3000 - Cell Name: preadipocyte (CL0002334)
Fold Change: 2.0946
Cell Significance Index: 40.8800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 2.0414
Cell Significance Index: 37.7300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 1.1591
Cell Significance Index: 58.5800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.8376
Cell Significance Index: 54.0400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5970
Cell Significance Index: 17.2000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.5521
Cell Significance Index: 109.5600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4118
Cell Significance Index: 44.8000 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.3379
Cell Significance Index: 4.8600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2620
Cell Significance Index: 33.5900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2487
Cell Significance Index: 89.2000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.2467
Cell Significance Index: 13.8500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.2334
Cell Significance Index: 12.1600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2059
Cell Significance Index: 39.1900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1728
Cell Significance Index: 17.0900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1632
Cell Significance Index: 112.8700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1618
Cell Significance Index: 146.1000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0939
Cell Significance Index: 176.7100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.0914
Cell Significance Index: 2.4500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0848
Cell Significance Index: 2.1200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0697
Cell Significance Index: 9.5700 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.0592
Cell Significance Index: 0.8500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0580
Cell Significance Index: 4.4500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0402
Cell Significance Index: 18.2600 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.0402
Cell Significance Index: 0.8600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0356
Cell Significance Index: 22.6200 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.0251
Cell Significance Index: 0.1700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0154
Cell Significance Index: 23.7300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0042
Cell Significance Index: -7.6700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0144
Cell Significance Index: -19.5800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0279
Cell Significance Index: -0.9800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0306
Cell Significance Index: -22.6500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0307
Cell Significance Index: -3.1400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0314
Cell Significance Index: -3.6600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0318
Cell Significance Index: -19.8400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0355
Cell Significance Index: -6.4000 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0368
Cell Significance Index: -20.1100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0402
Cell Significance Index: -22.6700 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.0439
Cell Significance Index: -0.2700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0488
Cell Significance Index: -36.9300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0530
Cell Significance Index: -7.7100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0577
Cell Significance Index: -42.3200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0698
Cell Significance Index: -14.0100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0947
Cell Significance Index: -41.8700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1064
Cell Significance Index: -18.1700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1172
Cell Significance Index: -33.7300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.1183
Cell Significance Index: -7.1000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1227
Cell Significance Index: -25.8500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1297
Cell Significance Index: -5.8800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1686
Cell Significance Index: -11.6600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1878
Cell Significance Index: -4.0000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.2045
Cell Significance Index: -4.4300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.2199
Cell Significance Index: -27.0400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3038
Cell Significance Index: -31.6300 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3107
Cell Significance Index: -35.4700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3122
Cell Significance Index: -10.0000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.3151
Cell Significance Index: -40.7100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3332
Cell Significance Index: -38.1700 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.3559
Cell Significance Index: -5.7100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.4315
Cell Significance Index: -20.2800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4546
Cell Significance Index: -27.9400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.4596
Cell Significance Index: -13.1800 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.5047
Cell Significance Index: -8.7000 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.5304
Cell Significance Index: -13.5500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.5440
Cell Significance Index: -36.5800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5617
Cell Significance Index: -44.4900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.5641
Cell Significance Index: -42.0400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.6106
Cell Significance Index: -31.7200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.6136
Cell Significance Index: -37.6200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.6374
Cell Significance Index: -45.0800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.6430
Cell Significance Index: -29.9800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.6461
Cell Significance Index: -28.5800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.6549
Cell Significance Index: -10.9600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.6837
Cell Significance Index: -43.0900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7281
Cell Significance Index: -38.2300 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.7543
Cell Significance Index: -12.4300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.7790
Cell Significance Index: -29.5000 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -0.8088
Cell Significance Index: -4.4100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.8744
Cell Significance Index: -27.8500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.9085
Cell Significance Index: -29.7500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.9480
Cell Significance Index: -33.2100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.9773
Cell Significance Index: -27.8900 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -1.0611
Cell Significance Index: -46.1400 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -1.0771
Cell Significance Index: -39.5400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -1.0989
Cell Significance Index: -30.7100 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: -1.1407
Cell Significance Index: -12.2300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3788913804
Symbol: WIPF1_HUMAN
Name: WAS/WASL-interacting protein family member 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9405671
Title: WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells.
PubMed ID: 9405671
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10202051
Title: Mutations that cause the Wiskott-Aldrich syndrome impair the interaction of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein.
PubMed ID: 10202051
PubMed ID: 10878810
Title: A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization.
PubMed ID: 10878810
DOI: 10.1038/35017080
PubMed ID: 19367720
Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.
PubMed ID: 19367720
DOI: 10.1021/pr800500r
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19798448
Title: Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis.
PubMed ID: 19798448
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19910490
Title: Actin-binding protein-1 interacts with WASp-interacting protein to regulate growth factor-induced dorsal ruffle formation.
PubMed ID: 19910490
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22231303
Title: A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP.
PubMed ID: 22231303
DOI: 10.1084/jem.20110896
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 16275905
Title: Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly.
PubMed ID: 16275905
Sequence Information:
- Length: 503
- Mass: 51258
- Checksum: 09B7A95E6808A46D
- Sequence:
MPVPPPPAPP PPPTFALANT EKPTLNKTEQ AGRNALLSDI SKGKKLKKTV TNDRSAPILD KPKGAGAGGG GGGFGGGGGF GGGGGGGGGG SFGGGGPPGL GGLFQAGMPK LRSTANRDND SGGSRPPLLP PGGRSTSAKP FSPPSGPGRF PVPSPGHRSG PPEPQRNRMP PPRPDVGSKP DSIPPPVPST PRPIQSSPHN RGSPPVPGGP RQPSPGPTPP PFPGNRGTAL GGGSIRQSPL SSSSPFSNRP PLPPTPSRAL DDKPPPPPPP VGNRPSIHRE AVPPPPPQNN KPPVPSTPRP SASSQAPPPP PPPSRPGPPP LPPSSSGNDE TPRLPQRNLS LSSSTPPLPS PGRSGPLPPP PSERPPPPVR DPPGRSGPLP PPPPVSRNGS TSRALPATPQ LPSRSGVDSP RSGPRPPLPP DRPSAGAPPP PPPSTSIRNG FQDSPCEDEW ESRFYFHPIS DLPPPEPYVQ TTKSYPSKLA RNESRSGSNR RERGAPPLPP IPR
Genular Protein ID: 4207210592
Symbol: Q2YDC4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 403
- Mass: 40479
- Checksum: 97A90B3546A46143
- Sequence:
MPVPPPPAPP PPPTFALANT EKPTLNKTEQ AGRNALLSDI SKGKKLKKTV TNDRSAPILD KPKGAGAGGG GGGFGGGGGF GGGGGGGGGG SFGGGGPPGL GGLFQAGMPK LRSTANRDND SGGSRPPLLP PGGRSTSAKP FSPPSGPGRF PVPSPGHRSG PPEPQRNRMP PPRPDVGSKP DSIPPPVPST PRPIQSSLHN RGSPPVPGGP RQPSPGPTPP PFPGNRGTAL GGGSIRQSPL SSSSPFSNRP PLPPTPSRAL DDKPPPPPPP VGNRPSIHRE AVPPPPPQNN KPPVPSTPRP SASSQAPPPP PPPSRPGPPP LPPSSSGNDE TPRLPQRNLS LSSSTPPLPS PGRSGPLPPP PSERPPPPVR DPPGRSGMTR RGVSCFQNPA CPNVPIILSV KIV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.