Details for: ZNF217

Gene ID: 7764

Symbol: ZNF217

Ensembl ID: ENSG00000171940

Description: zinc finger protein 217

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 134.3661
    Cell Significance Index: -20.9000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 49.5130
    Cell Significance Index: -20.1200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 48.9438
    Cell Significance Index: -23.1100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 44.4025
    Cell Significance Index: -22.8400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 21.3461
    Cell Significance Index: -20.3800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 17.0485
    Cell Significance Index: -21.0200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.1677
    Cell Significance Index: -21.8800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.8539
    Cell Significance Index: -17.9800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.4143
    Cell Significance Index: -21.3700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.6233
    Cell Significance Index: -7.9300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.0380
    Cell Significance Index: 105.8700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.8944
    Cell Significance Index: 308.1000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.5192
    Cell Significance Index: 40.5700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3126
    Cell Significance Index: 260.5000
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 1.2812
    Cell Significance Index: 7.8900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.2308
    Cell Significance Index: 33.5000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2087
    Cell Significance Index: 131.4700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.1462
    Cell Significance Index: 26.4800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.0982
    Cell Significance Index: 197.9800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.0901
    Cell Significance Index: 49.4100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.0545
    Cell Significance Index: 129.6700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.8280
    Cell Significance Index: 7.6300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.8117
    Cell Significance Index: 443.2800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.8055
    Cell Significance Index: 17.4500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5462
    Cell Significance Index: 493.2000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.5416
    Cell Significance Index: 25.4600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.5030
    Cell Significance Index: 23.4500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.4770
    Cell Significance Index: 6.7900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4513
    Cell Significance Index: 199.5300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4096
    Cell Significance Index: 40.5200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.3907
    Cell Significance Index: 5.8600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.3586
    Cell Significance Index: 10.2800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3490
    Cell Significance Index: 24.6800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3394
    Cell Significance Index: 21.9000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3313
    Cell Significance Index: 45.5000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.2686
    Cell Significance Index: 4.9700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2149
    Cell Significance Index: 40.8900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.1889
    Cell Significance Index: 1.5400
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.1836
    Cell Significance Index: 1.9000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.1786
    Cell Significance Index: 3.4900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1772
    Cell Significance Index: 9.2300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1613
    Cell Significance Index: 8.1500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.1406
    Cell Significance Index: 3.7600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1228
    Cell Significance Index: 9.1500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1220
    Cell Significance Index: 3.4100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0962
    Cell Significance Index: 11.3400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0948
    Cell Significance Index: 3.3300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0856
    Cell Significance Index: 2.2500
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.0756
    Cell Significance Index: 0.4700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0717
    Cell Significance Index: 12.2400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0657
    Cell Significance Index: 1.9300
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 0.0656
    Cell Significance Index: 0.2000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0508
    Cell Significance Index: 6.5700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0343
    Cell Significance Index: 0.7300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0067
    Cell Significance Index: 0.8600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0006
    Cell Significance Index: -1.1500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0017
    Cell Significance Index: -1.1800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0041
    Cell Significance Index: -2.9700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0087
    Cell Significance Index: -5.4100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0095
    Cell Significance Index: -1.0900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0114
    Cell Significance Index: -8.4100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0116
    Cell Significance Index: -7.3600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0120
    Cell Significance Index: -22.1900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0148
    Cell Significance Index: -22.8300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0165
    Cell Significance Index: -1.6900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0193
    Cell Significance Index: -26.2100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0212
    Cell Significance Index: -3.0800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0239
    Cell Significance Index: -13.4600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0270
    Cell Significance Index: -12.2500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0289
    Cell Significance Index: -21.8500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0485
    Cell Significance Index: -17.4000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0553
    Cell Significance Index: -11.0900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0557
    Cell Significance Index: -0.7600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0584
    Cell Significance Index: -12.3000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0605
    Cell Significance Index: -17.4100
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.0637
    Cell Significance Index: -0.4200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0711
    Cell Significance Index: -8.2900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0718
    Cell Significance Index: -1.4900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0732
    Cell Significance Index: -8.3900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0955
    Cell Significance Index: -7.3300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1294
    Cell Significance Index: -2.1800
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.1305
    Cell Significance Index: -0.9800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1522
    Cell Significance Index: -4.3900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1558
    Cell Significance Index: -8.7400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1670
    Cell Significance Index: -2.8000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1930
    Cell Significance Index: -11.8600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2032
    Cell Significance Index: -21.1600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2084
    Cell Significance Index: -5.2100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2253
    Cell Significance Index: -17.8400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2813
    Cell Significance Index: -9.0100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2872
    Cell Significance Index: -17.6100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.3112
    Cell Significance Index: -1.8800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3187
    Cell Significance Index: -21.4300
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.3333
    Cell Significance Index: -4.9200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3479
    Cell Significance Index: -15.3900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3664
    Cell Significance Index: -23.0900
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.3864
    Cell Significance Index: -6.2000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4096
    Cell Significance Index: -15.0400
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.4127
    Cell Significance Index: -5.3200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4420
    Cell Significance Index: -15.3600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Transcription Factor Function**: ZNF217 acts as a transcriptional repressor, negatively regulating the expression of genes involved in cellular differentiation, proliferation, and survival. 2. **DNA Binding Specificity**: ZNF217 exhibits specific binding affinity for RNA polymerase II-cis-regulatory region sequences, indicating its role in regulating transcriptional initiation. 3. **Cellular Expression**: ZNF217 is expressed in epithelial cells, immune cells, and stem cells, highlighting its involvement in tissue development and homeostasis. 4. **Interactions with Other Proteins**: ZNF217 interacts with various transcriptional regulators, including estrogen receptors and histone deacetylase complexes, to modulate gene expression. **Pathways and Functions:** 1. **DNA-Binding Transcription Factor Activity**: ZNF217 regulates transcriptional initiation by binding to specific DNA sequences and recruiting RNA polymerase II. 2. **Negative Regulation of DNA- Templated Transcription**: ZNF217 acts as a transcriptional repressor, inhibiting the expression of genes involved in cellular differentiation and proliferation. 3. **Estrogen-Dependent Gene Expression**: ZNF217 interacts with estrogen receptors to modulate the expression of estrogen-responsive genes. 4. **Histone Deacetylase Complex**: ZNF217 interacts with histone deacetylases to regulate chromatin structure and gene expression. 5. **Signal Transduction**: ZNF217 is involved in signal transduction pathways, including those mediated by estrogen receptors and nuclear receptors. **Clinical Significance:** 1. **Cancer Association**: ZNF217 has been implicated in the regulation of genes involved in cancer progression, highlighting its potential as a therapeutic target. 2. **Inflammatory Diseases**: ZNF217's involvement in immune cell function and inflammation suggests its potential role in the pathogenesis of inflammatory diseases. 3. **Reproductive Health**: ZNF217's interaction with estrogen receptors and its expression in reproductive tissues suggest its potential role in reproductive health and disorders. 4. **Neurological Disorders**: ZNF217's involvement in signal transduction pathways may contribute to its potential role in neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, ZNF217 is a multifunctional transcription factor that regulates gene expression in various cell types, influencing cellular differentiation, proliferation, and survival. Its clinical significance is underscored by its involvement in cancer, inflammatory diseases, reproductive health, and neurological disorders. Further research is necessary to elucidate the full scope of ZNF217's regulatory functions and its potential as a therapeutic target.

Genular Protein ID: 1925430053

Symbol: ZN217_HUMAN

Name: Zinc finger protein 217

UniProtKB Accession Codes:

O75362 E1P5Y6 Q14DB8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9671742

Title: Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma.

PubMed ID: 9671742

DOI: 10.1073/pnas.95.15.8703

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12493763

Title: A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.

PubMed ID: 12493763

DOI: 10.1074/jbc.m208992200

PubMed ID: 16203743

Title: ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction.

PubMed ID: 16203743

DOI: 10.1093/hmg/ddi352

PubMed ID: 17259635

Title: Identification of genes directly regulated by the oncogene ZNF217 using chromatin immunoprecipitation (ChIP)-chip assays.

PubMed ID: 17259635

DOI: 10.1074/jbc.m611752200

PubMed ID: 18625718

Title: Genome analysis identifies the p15ink4b tumor suppressor as a direct target of the ZNF217/CoREST complex.

PubMed ID: 18625718

DOI: 10.1128/mcb.00246-08

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 16940172

Title: Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins.

PubMed ID: 16940172

DOI: 10.1128/mcb.00680-06

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 1048
  • Mass: 115272
  • Checksum: 797FC620817D1E1F
  • Sequence:
    • MQSKVTGNMP TQSLLMYMDG PEVIGSSLGS PMEMEDALSM KGTAVVPFRA TQEKNVIQIE 
GYMPLDCMFC SQTFTHSEDL NKHVLMQHRP TLCEPAVLRV EAEYLSPLDK SQVRTEPPKE 
KNCKENEFSC EVCGQTFRVA FDVEIHMRTH KDSFTYGCNM CGRRFKEPWF LKNHMRTHNG 
KSGARSKLQQ GLESSPATIN EVVQVHAAES ISSPYKICMV CGFLFPNKES LIEHRKVHTK 
KTAFGTSSAQ TDSPQGGMPS SREDFLQLFN LRPKSHPETG KKPVRCIPQL DPFTTFQAWQ 
LATKGKVAIC QEVKESGQEG STDNDDSSSE KELGETNKGS CAGLSQEKEK CKHSHGEAPS 
VDADPKLPSS KEKPTHCSEC GKAFRTYHQL VLHSRVHKKD RRAGAESPTM SVDGRQPGTC 
SPDLAAPLDE NGAVDRGEGG SEDGSEDGLP EGIHLDKNDD GGKIKHLTSS RECSYCGKFF 
RSNYYLNIHL RTHTGEKPYK CEFCEYAAAQ KTSLRYHLER HHKEKQTDVA AEVKNDGKNQ 
DTEDALLTAD SAQTKNLKRF FDGAKDVTGS PPAKQLKEMP SVFQNVLGSA VLSPAHKDTQ 
DFHKNAADDS ADKVNKNPTP AYLDLLKKRS AVETQANNLI CRTKADVTPP PDGSTTHNLE 
VSPKEKQTET AADCRYRPSV DCHEKPLNLS VGALHNCPAI SLSKSLIPSI TCPFCTFKTF 
YPEVLMMHQR LEHKYNPDVH KNCRNKSLLR SRRTGCPPAL LGKDVPPLSS FCKPKPKSAF 
PAQSKSLPSA KGKQSPPGPG KAPLTSGIDS STLAPSNLKS HRPQQNVGVQ GAATRQQQSE 
MFPKTSVSPA PDKTKRPETK LKPLPVAPSQ PTLGSSNING SIDYPAKNDS PWAPPGRDYF 
CNRSASNTAA EFGEPLPKRL KSSVVALDVD QPGANYRRGY DLPKYHMVRG ITSLLPQDCV 
YPSQALPPKP RFLSSSEVDS PNVLTVQKPY GGSGPLYTCV PAGSPASSST LEGKRPVSYQ 
HLSNSMAQKR NYENFIGNAH YRPNDKKT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.