Details for: SLMAP
Gene ID: 7871
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: SLMAP
Ensembl ID: ENSG00000163681
Description: sarcolemma associated protein
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 52.42rCSI 74.81%PRS 39.21
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CSI 46.79rCSI 67.14%PRS 29.3
-
CSI 38.86rCSI 59.35%PRS 36.87
-
CSI 38.2rCSI 64.12%PRS 23.47
-
CSI 37.67rCSI 60.58%PRS 25.35
-
CSI 27.31rCSI 33.97%PRS 22.15
-
CSI 26.47rCSI 64.33%PRS 22.76
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CSI 25.7rCSI 73.5%PRS 54.5
-
CSI 21.87rCSI 38.62%PRS 22.59
-
CSI 21.44rCSI 77.15%PRS 22.5
-
CSI 20.69rCSI 64.65%PRS 24.44
-
CSI 19.8rCSI 15.25%PRS 34.9
-
CSI 19.79rCSI 63.71%PRS 36.7
-
CSI 18.38rCSI 25.53%PRS 36.54
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CSI 18.16rCSI 44.95%PRS 34.7
-
CSI 18.03rCSI 21.53%PRS 23.41
-
CSI 17.3rCSI 21.52%PRS 39
-
CSI 15.73rCSI 59.45%PRS 24.3
-
CSI 15.43rCSI 48.27%PRS 26.45
-
CSI 15.37rCSI 23.48%PRS 44.95
-
CSI 15.02rCSI 38.84%PRS 33.5
-
CSI 14.67rCSI 23.4%PRS 31.45
-
CSI 14.45rCSI 22.82%PRS 37.28
-
CSI 14.33rCSI 41.48%PRS 39.34
-
CSI 13.56rCSI 9.73%PRS 48.22
-
CSI 13.12rCSI 34.82%PRS 50
-
CSI 12.74rCSI 14.71%PRS 31.95
-
CSI 12.17rCSI 15.68%PRS 24.24
-
CSI 11.74rCSI 14.62%PRS 47.51
-
CSI 11.52rCSI 10.09%PRS 45.82
-
CSI 11.45rCSI 67.42%PRS 24.62
-
CSI 10.69rCSI 18.85%PRS 35.51
-
CSI 10.44rCSI 13.39%PRS 34.85
-
CSI 10.1rCSI 25.62%PRS 28.71
-
CSI 9.88rCSI 23.76%PRS 47.36
-
CSI 9.48rCSI 25.24%PRS 30.75
-
CSI 9.22rCSI 20.37%PRS 26.94
-
CSI 9rCSI 7.27%PRS 48.09
-
CSI 8.94rCSI 23.23%PRS 42.65
-
CSI 8.89rCSI 20.53%PRS 30.2
-
CSI 8.83rCSI 10.34%PRS 50.21
-
CSI 8.75rCSI 12.12%PRS 42.87
-
CSI 8.64rCSI 11.56%PRS 44.17
-
CSI 8.59rCSI 20.97%PRS 33.91
-
CSI 8.42rCSI 11.47%PRS 31.4
-
CSI 8.3rCSI 6.75%PRS 37.41
-
CSI 7.65rCSI 56.23%PRS 26.2
-
CSI 7.5rCSI 13.48%PRS 30.98
-
CSI 7.34rCSI 17.49%PRS 56.96
-
CSI 7.3rCSI 11.61%PRS 30.97
-
CSI 7.24rCSI 11.07%PRS 52.92
-
CSI 7.19rCSI 24.62%PRS 30.61
-
CSI 7.18rCSI 9.77%PRS 49.28
-
CSI 7.16rCSI 16.37%PRS 36
-
CSI 7.16rCSI 8.71%PRS 43.58
-
CSI 7.06rCSI 5.23%PRS 31.4
-
CSI 7.02rCSI 5.57%PRS 57.68
-
CSI 6.92rCSI 22.43%PRS 40.12
-
CSI 6.71rCSI 18.81%PRS 51.43
-
CSI 6.39rCSI 39.91%PRS 30.21
-
CSI 6.26rCSI 8.56%PRS 40.73
-
CSI 6.24rCSI 8.01%PRS 33.85
-
CSI 6.15rCSI 11.53%PRS 27.96
-
CSI 6.05rCSI 12.01%PRS 36.65
-
CSI 6.03rCSI 51.94%PRS 25.22
-
CSI 5.83rCSI 6.08%PRS 37.15
-
CSI 5.82rCSI 24.15%PRS 48.38
-
CSI 5.79rCSI 7.27%PRS 45.41
-
CSI 5.76rCSI 13.14%PRS 31.47
-
CSI 5.74rCSI 8.31%PRS 51.85
-
CSI 5.67rCSI 16.83%PRS 47.48
-
CSI 5.49rCSI 11.38%PRS 35.34
-
CSI 5.43rCSI 9.68%PRS 52.63
-
CSI 5.4rCSI 4.2%PRS 51.66
-
CSI 5.29rCSI 14.25%PRS 45.31
-
CSI 5.28rCSI 29.85%PRS 24.97
-
CSI 5.26rCSI 4%PRS 46.46
-
CSI 5.23rCSI 8.47%PRS 35.68
-
CSI 5.2rCSI 11.45%PRS 50.91
-
CSI 5.19rCSI 13.12%PRS 43.93
-
CSI 5.09rCSI 4.48%PRS 27.36
-
CSI 5.09rCSI 8.92%PRS 29.79
-
CSI 5rCSI 19.55%PRS 16.4
-
CSI 4.93rCSI 7.95%PRS 46.76
-
CSI 4.93rCSI 3.9%PRS 26.08
-
CSI 4.81rCSI 3.73%PRS 36.34
-
CSI 4.72rCSI 12.42%PRS 59.84
-
CSI 4.64rCSI 8.3%PRS 34.89
-
CSI 4.59rCSI 6.5%PRS 34.18
-
CSI 4.57rCSI 4.32%PRS 37.74
-
CSI 4.56rCSI 17.63%PRS 56.55
-
CSI 4.51rCSI 7.38%PRS 28.72
-
CSI 4.41rCSI 4.96%PRS 52.16
-
CSI 4.36rCSI 5.12%PRS 40.23
-
CSI 4.22rCSI 9.23%PRS 46.29
-
CSI 4.17rCSI 4.02%PRS 37.24
-
CSI 4.17rCSI 8.38%PRS 27.93
-
CSI 4.16rCSI 8.44%PRS 22.06
-
CSI 4.14rCSI 9.12%PRS 40.43
-
CSI 4.12rCSI 3.8%PRS 37.62
-
CSI 0.2rCSI 2.6%PRS 57.7%
-
CSI 0.3rCSI 4.1%PRS 65.1%
-
CSI 0.3rCSI 1.5%PRS 56.7%
-
CSI 0.4rCSI 3.0%PRS 57.3%
-
CSI 0.5rCSI 1.7%PRS 47.7%
-
CSI 0.5rCSI 0.5%PRS 44.8%
-
CSI 0.5rCSI 4.2%PRS 36.1%
-
CSI 0.6rCSI 3.9%PRS 32.9%
-
CSI 0.6rCSI 2.9%PRS 52.6%
-
CSI 0.6rCSI 2.6%PRS 25.7%
-
CSI 0.6rCSI 4.9%PRS 35.0%
-
CSI 0.6rCSI 3.1%PRS 46.8%
-
CSI 0.6rCSI 4.5%PRS 34.4%
-
CSI 0.6rCSI 3.5%PRS 68.0%
-
CSI 0.6rCSI 5.4%PRS 27.1%
-
CSI 0.6rCSI 4.5%PRS 34.3%
-
CSI 0.6rCSI 2.5%PRS 40.6%
-
CSI 0.6rCSI 1.7%PRS 52.4%
-
CSI 0.6rCSI 0.9%PRS 40.4%
-
CSI 0.7rCSI 7.4%PRS 33.5%
-
CSI 0.7rCSI 4.0%PRS 62.7%
-
CSI 0.7rCSI 1.7%PRS 34.0%
-
CSI 0.7rCSI 4.5%PRS 36.4%
-
CSI 0.7rCSI 2.8%PRS 48.4%
-
CSI 0.7rCSI 3.1%PRS 35.2%
-
CSI 0.7rCSI 2.5%PRS 54.7%
-
CSI 0.7rCSI 2.1%PRS 29.5%
-
CSI 0.8rCSI 3.4%PRS 62.8%
-
CSI 0.8rCSI 2.1%PRS 40.7%
-
CSI 0.8rCSI 1.7%PRS 51.5%
-
CSI 0.8rCSI 2.9%PRS 52.7%
-
CSI 0.8rCSI 1.3%PRS 34.7%
-
CSI 0.8rCSI 3.9%PRS 57.3%
-
CSI 0.8rCSI 2.4%PRS 39.1%
-
CSI 0.9rCSI 3.7%PRS 34.5%
-
CSI 0.9rCSI 1.3%PRS 53.1%
-
CSI 0.9rCSI 0.8%PRS 42.9%
-
CSI 0.9rCSI 1.8%PRS 58.2%
-
CSI 0.9rCSI 4.6%PRS 36.4%
-
CSI 0.9rCSI 5.2%PRS 35.6%
-
CSI 0.9rCSI 7.2%PRS 59.3%
-
CSI 1.0rCSI 1.9%PRS 57.4%
-
CSI 1.0rCSI 4.6%PRS 60.0%
-
CSI 1.0rCSI 2.2%PRS 56.9%
-
CSI 1.0rCSI 4.8%PRS 35.6%
-
CSI 1.1rCSI 2.2%PRS 59.2%
-
CSI 1.1rCSI 2.1%PRS 54.1%
-
CSI 1.1rCSI 2.1%PRS 38.0%
-
CSI 1.1rCSI 1.3%PRS 43.2%
-
CSI 1.1rCSI 0.8%PRS 45.3%
-
CSI 1.2rCSI 3.4%PRS 52.5%
-
CSI 1.3rCSI 1.7%PRS 59.0%
-
CSI 1.3rCSI 2.8%PRS 33.9%
-
CSI 1.3rCSI 11.3%PRS 40.4%
-
CSI 1.4rCSI 1.4%PRS 38.7%
-
CSI 1.4rCSI 1.8%PRS 41.0%
-
CSI 1.4rCSI 4.0%PRS 34.3%
-
CSI 1.5rCSI 34.5%PRS 59.7%
-
CSI 1.5rCSI 5.7%PRS 32.3%
-
CSI 1.5rCSI 2.3%PRS 33.9%
-
CSI 1.6rCSI 3.2%PRS 33.2%
-
CSI 1.6rCSI 3.0%PRS 45.5%
-
CSI 1.6rCSI 5.3%PRS 27.3%
-
CSI 1.6rCSI 2.9%PRS 31.8%
-
CSI 1.6rCSI 1.1%PRS 38.3%
-
CSI 1.7rCSI 2.3%PRS 34.5%
-
CSI 1.7rCSI 3.8%PRS 35.8%
-
CSI 1.7rCSI 2.5%PRS 33.7%
-
CSI 1.7rCSI 4.4%PRS 46.6%
-
CSI 1.7rCSI 2.0%PRS 28.0%
-
CSI 1.8rCSI 1.3%PRS 39.2%
-
CSI 1.8rCSI 2.6%PRS 39.0%
-
CSI 1.8rCSI 2.6%PRS 37.4%
-
CSI 1.8rCSI 2.3%PRS 32.9%
-
CSI 1.8rCSI 19.5%PRS 39.8%
-
CSI 1.9rCSI 4.2%PRS 24.0%
-
CSI 1.9rCSI 2.8%PRS 46.7%
-
CSI 1.9rCSI 9.4%PRS 47.1%
-
CSI 1.9rCSI 3.6%PRS 60.9%
-
CSI 1.9rCSI 4.0%PRS 44.9%
-
CSI 1.9rCSI 9.7%PRS 76.2%
-
CSI 1.9rCSI 5.0%PRS 36.7%
-
CSI 1.9rCSI 4.2%PRS 28.5%
-
CSI 1.9rCSI 2.3%PRS 55.8%
-
CSI 2.0rCSI 9.5%PRS 39.3%
-
CSI 2.0rCSI 2.1%PRS 36.7%
-
CSI 2.0rCSI 13.5%PRS 35.4%
-
CSI 2.0rCSI 10.0%PRS 46.4%
-
CSI 2.0rCSI 1.8%PRS 36.0%
-
CSI 2.0rCSI 8.6%PRS 36.0%
-
CSI 2.0rCSI 3.6%PRS 44.9%
-
CSI 2.0rCSI 2.7%PRS 49.1%
-
CSI 2.0rCSI 4.9%PRS 47.9%
-
CSI 2.1rCSI 3.1%PRS 40.9%
-
CSI 2.1rCSI 2.5%PRS 55.3%
-
CSI 2.1rCSI 2.2%PRS 42.0%
-
CSI 2.1rCSI 6.3%PRS 35.4%
-
CSI 2.2rCSI 5.2%PRS 53.8%
-
CSI 2.2rCSI 8.5%PRS 55.9%
-
CSI 2.2rCSI 13.7%PRS 24.8%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 1738165906
Symbol: SLMAP_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10986292
Title: Alternative splicing, expression, and genomic structure of the 3' region of the gene encoding the sarcolemmal-associated proteins (SLAPs) defines a novel class of coiled-coil tail-anchored membrane proteins.
PubMed ID: 10986292
PubMed ID: 11042152
Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.
PubMed ID: 11042152
DOI: 10.1101/gr.140200
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10997877
Title: Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10997877
PubMed ID: 19538755
Title: Hydrophobic profiles of the tail anchors in SLMAP dictate subcellular targeting.
PubMed ID: 19538755
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 29063833
Title: SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
PubMed ID: 29063833
DOI: 10.7554/elife.30278
PubMed ID: 30622739
Title: Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
PubMed ID: 30622739
Sequence Information:
- Length: 828
- Mass: 95198
- Checksum: 20F5FA38174CA383
- Sequence:
MPSALAIFTC RPNSHPFQER HVYLDEPIKI GRSVARCRPA QNNATFDCKV LSRNHALVWF DHKTGKFYLQ DTKSSNGTFI NSQRLSRGSE ESPPCEILSG DIIQFGVDVT ENTRKVTHGC IVSTIKLFLP DGMEARLRSD VIHAPLPSPV DKVAANTPSM YSQELFQLSQ YLQEALHREQ MLEQKLATLQ RLLAITQEAS DTSWQALIDE DRLLSRLEVM GNQLQACSKN QTEDSLRKEL IALQEDKHNY ETTAKESLRR VLQEKIEVVR KLSEVERSLS NTEDECTHLK EMNERTQEEL RELANKYNGA VNEIKDLSDK LKVAEGKQEE IQQKGQAEKK ELQHKIDEME EKEQELQAKI EALQADNDFT NERLTALQVR LEHLQEKTLK ECSSLEHLLS KSGGDCTFIH QFIECQKKLI VEGHLTKAVE ETKLSKENQT RAKESDFSDT LSPSKEKSSD DTTDAQMDEQ DLNEPLAKVS LLKDDLQGAQ SEIEAKQEIQ HLRKELIEAQ ELARTSKQKC FELQALLEEE RKAYRNQVEE STKQIQVLQA QLQRLHIDTE NLREEKDSEI TSTRDELLSA RDEILLLHQA AAKVASERDT DIASLQEELK KVRAELERWR KAASEYEKEI TSLQNSFQLR CQQCEDQQRE EATRLQGELE KLRKEWNALE TECHSLKREN VLLSSELQRQ EKELHNSQKQ SLELTSDLSI LQMSRKELEN QVGSLKEQHL RDSADLKTLL SKAENQAKDV QKEYEKTQTV LSELKLKFEM TEQEKQSITD ELKQCKNNLK LLREKGNNKP WPWMPMLAAL VAVTAIVLYV PGLARASP
Genular Protein ID: 1135693452
Symbol: B7Z6C7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 296
- Mass: 34214
- Checksum: 388D4F3B2421F5AC
- Sequence:
MDEQDLNEPL AKVSLLKAQL QRLHIDTENL REEKDSGITS TRDELLSARD EILLLHQAAA KVASERDTDI ASLQEELKKV RAELERWRKA ASEYEKEITS LQNSFQLRCQ QCEDQQREEA TRLQGELEKL RKEWNALETE CHSLKRENVL LSSELQRQEK ELHNSQKQSL ELTSDLSILQ MSRKELENQV GSLKEQHLRD SADLKTLLSK AENQAKDVQK EYEKTQTVLS ELKLKFEMTE QEKQSITDEL KQCKNNLKLL REKGNNKPWP WMPMLAALVA VTAIVLYVPG LARASP
Genular Protein ID: 348158641
Symbol: B7Z964_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 362
- Mass: 42037
- Checksum: 1BA54778FD979738
- Sequence:
MDEQDLNEPL AKVSLLKDDL QGAQSEIEAK QEIQHLRKEL IEAQELARTS KQKCFELQAL LEEERKAYRN QVEESTKQIQ VLQAQLQRLH IDTENLREEK DSEITSTRDE LLSARDEILL LHQAAAKVAS ERDTDIASLQ EELKKVRAEL ERWRKAASEY EKEITSLQNS FQLRCQQCED QQREEATRLQ GELEKLRKEW NALETECHSL KRENVLLSSE LQRQEKELHN SQKQSLELTS DLSILQMSRK ELENQVGSLK EQHLRDSADL KTLLSKAENQ AKDVQKEYEK TQTVLSELKL KFEMTEQEKQ SITDELKQCK NNLKLLREKG NNKPWPWMPM LAALVAVTAI VLYVPGLARA SP