Details for: MANF

Gene ID: 7873

Symbol: MANF

Ensembl ID: ENSG00000145050

Description: mesencephalic astrocyte derived neurotrophic factor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 318.1711
    Cell Significance Index: -49.4900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 176.7442
    Cell Significance Index: -44.8300
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 127.7832
    Cell Significance Index: -52.6400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 116.4740
    Cell Significance Index: -54.9900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 101.4609
    Cell Significance Index: -52.1900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 82.1433
    Cell Significance Index: -55.1200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 41.5627
    Cell Significance Index: -51.2500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.6999
    Cell Significance Index: -36.7000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.1853
    Cell Significance Index: -52.0300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.6790
    Cell Significance Index: -32.8000
  • Cell Name: peg cell (CL4033014)
    Fold Change: 6.0699
    Cell Significance Index: 140.2400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.5829
    Cell Significance Index: -10.0300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.3487
    Cell Significance Index: 63.9300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.2287
    Cell Significance Index: 166.1000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.8437
    Cell Significance Index: 38.5900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.8084
    Cell Significance Index: 987.5900
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 1.8061
    Cell Significance Index: 19.1900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.6097
    Cell Significance Index: 75.0500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.4303
    Cell Significance Index: 11.4200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.3565
    Cell Significance Index: 244.5300
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 1.2852
    Cell Significance Index: 9.2300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.2618
    Cell Significance Index: 163.0200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.2445
    Cell Significance Index: 43.2500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.2396
    Cell Significance Index: 11.4200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.1922
    Cell Significance Index: 146.5900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.1881
    Cell Significance Index: 61.7200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.0956
    Cell Significance Index: 51.4900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.9819
    Cell Significance Index: 134.8400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7946
    Cell Significance Index: 54.9500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.7925
    Cell Significance Index: 20.8400
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.7626
    Cell Significance Index: 8.2900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.7300
    Cell Significance Index: 9.9600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.7284
    Cell Significance Index: 20.8800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5909
    Cell Significance Index: 75.7500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5639
    Cell Significance Index: 249.3200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5270
    Cell Significance Index: 104.5800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4942
    Cell Significance Index: 22.4000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.4752
    Cell Significance Index: 81.1500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.4745
    Cell Significance Index: 5.3900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4392
    Cell Significance Index: 31.0600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3740
    Cell Significance Index: 10.7800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3292
    Cell Significance Index: 38.8300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2631
    Cell Significance Index: 50.0600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2514
    Cell Significance Index: 226.9700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.2129
    Cell Significance Index: 161.1700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1635
    Cell Significance Index: 16.1700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0730
    Cell Significance Index: 11.8800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0681
    Cell Significance Index: 1.1400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0395
    Cell Significance Index: 7.9200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0375
    Cell Significance Index: 1.0000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0364
    Cell Significance Index: 2.3500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0134
    Cell Significance Index: 9.7900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0034
    Cell Significance Index: -2.5500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0062
    Cell Significance Index: -3.8800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0110
    Cell Significance Index: -20.6800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0287
    Cell Significance Index: -19.8500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0316
    Cell Significance Index: -58.3400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0336
    Cell Significance Index: -0.9400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0394
    Cell Significance Index: -60.7100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0423
    Cell Significance Index: -15.1600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0476
    Cell Significance Index: -4.8600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0507
    Cell Significance Index: -69.0000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0623
    Cell Significance Index: -39.5500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0632
    Cell Significance Index: -35.6700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0770
    Cell Significance Index: -8.7900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0903
    Cell Significance Index: -19.0300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1010
    Cell Significance Index: -45.8500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1141
    Cell Significance Index: -2.4300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1185
    Cell Significance Index: -4.1700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1307
    Cell Significance Index: -6.8600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1852
    Cell Significance Index: -21.2200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1873
    Cell Significance Index: -53.8900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2470
    Cell Significance Index: -6.3100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2675
    Cell Significance Index: -38.8900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2941
    Cell Significance Index: -34.2700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3058
    Cell Significance Index: -19.2800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3235
    Cell Significance Index: -10.3600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4202
    Cell Significance Index: -10.5100
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.4513
    Cell Significance Index: -6.3300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5007
    Cell Significance Index: -52.1300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.5186
    Cell Significance Index: -15.2300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5678
    Cell Significance Index: -44.9700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.5704
    Cell Significance Index: -5.9100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.5797
    Cell Significance Index: -32.5300
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.5890
    Cell Significance Index: -3.6600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.5996
    Cell Significance Index: -17.6600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.6041
    Cell Significance Index: -3.6500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.6072
    Cell Significance Index: -46.6000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.6592
    Cell Significance Index: -40.5200
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.6614
    Cell Significance Index: -8.4700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.6895
    Cell Significance Index: -46.3600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.7408
    Cell Significance Index: -19.8200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.7551
    Cell Significance Index: -16.3600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7650
    Cell Significance Index: -46.9000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.9724
    Cell Significance Index: -14.5700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -1.0789
    Cell Significance Index: -19.0700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.0831
    Cell Significance Index: -47.9100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.1526
    Cell Significance Index: -42.3100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.1554
    Cell Significance Index: -29.7000
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -1.2518
    Cell Significance Index: -11.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MANF is a small, arginine-rich protein that belongs to the neurotrophic factor family. Its expression is regulated by various cellular stressors, including endoplasmic reticulum (ER) stress, calcium overload, and unfolded protein. MANF exhibits a unique ability to bind to various cellular components, including proteins, lipids, and nucleic acids, which contributes to its diverse physiological functions. Notably, MANF's expression is significantly upregulated in response to ER stress, a condition characterized by the accumulation of misfolded proteins in the ER lumen. This suggests that MANF may play a protective role against ER stress-induced cell death. **Pathways and Functions:** MANF's involvement in various cellular processes can be attributed to its interactions with multiple signaling pathways. Some of the key pathways and functions associated with MANF include: 1. **Neuron Development and Differentiation:** MANF plays a crucial role in the development and maturation of dopaminergic neurons, a type of neuron involved in motor control and reward processing. 2. **Endoplasmic Reticulum Stress Response:** MANF's expression is upregulated in response to ER stress, suggesting its role as a protective factor against ER stress-induced cell death. 3. **Growth Factor Activity:** MANF exhibits growth factor activity, promoting cell proliferation, differentiation, and survival in various cell types. 4. **Platelet Activation and Aggregation:** MANF is involved in platelet activation and aggregation, a process critical for hemostasis and blood clot formation. 5. **Vasoconstriction and Ischemic Response:** MANF's expression is also observed in vascular smooth muscle cells, where it may play a role in vasoconstriction and the ischemic response to lowering systemic arterial blood pressure. **Clinical Significance:** The multifaceted nature of MANF highlights its potential as a therapeutic target for various diseases, including: 1. **Neurodegenerative Disorders:** MANF's role in neuron development and differentiation makes it an attractive target for the treatment of neurodegenerative disorders, such as Parkinson's disease and Huntington's disease. 2. **Cardiovascular Conditions:** MANF's involvement in platelet activation and aggregation suggests its potential as a therapeutic target for cardiovascular conditions, such as myocardial infarction and stroke. 3. **Cancer:** MANF's expression in various cancer cell types, including extravillous trophoblast and IgA plasma cell, highlights its potential as a biomarker for cancer diagnosis and treatment. In conclusion, MANF is a complex gene with a wide range of cellular and physiological functions. Its multifaceted nature highlights its potential as a therapeutic target for various diseases, including neurodegenerative disorders, cardiovascular conditions, and cancer. Further research is needed to fully elucidate the mechanisms underlying MANF's functions and its potential as a therapeutic agent.

Genular Protein ID: 1996416816

Symbol: MANF_HUMAN

Name: Arginine-rich protein

UniProtKB Accession Codes:

P55145 Q14CX4 Q86U67 Q96IS4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CPTAC 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 15 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8649854

Title: A gene from human chromosomal band 3p21.1 encodes a highly conserved arginine-rich protein and is mutated in renal cell carcinomas.

PubMed ID: 8649854

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 12794311

Title: MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons.

PubMed ID: 12794311

DOI: 10.1385/jmn:20:2:173

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 18561914

Title: Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death.

PubMed ID: 18561914

DOI: 10.1016/j.yexcr.2008.05.001

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22637475

Title: Mesencephalic astrocyte-derived neurotrophic factor protects the heart from ischemic damage and is selectively secreted upon sarco/endoplasmic reticulum calcium depletion.

PubMed ID: 22637475

DOI: 10.1074/jbc.m112.356345

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29497057

Title: Conserved roles of C. elegans and human MANFs in sulfatide binding and cytoprotection.

PubMed ID: 29497057

DOI: 10.1038/s41467-018-03355-0

PubMed ID: 19258449

Title: The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional.

PubMed ID: 19258449

DOI: 10.1093/protein/gzn080

PubMed ID: 8971156

Title: Mutations in the arginine-rich protein gene, in lung, breast, and prostate cancers, and in squamous cell carcinoma of the head and neck.

PubMed ID: 8971156

PubMed ID: 9174057

Title: Mutations in the arginine-rich protein gene (ARP) in pancreatic cancer.

PubMed ID: 9174057

DOI: 10.1038/sj.onc.1201054

PubMed ID: 26077850

Title: High diagnostic yield of clinical exome sequencing in Middle Eastern patients with Mendelian disorders.

PubMed ID: 26077850

DOI: 10.1007/s00439-015-1575-0

PubMed ID: 33500254

Title: Loss of MANF causes childhood-onset syndromic diabetes due to increased endoplasmic reticulum stress.

PubMed ID: 33500254

DOI: 10.2337/db20-1174

Sequence Information:

  • Length: 182
  • Mass: 20700
  • Checksum: EE25A5D1A58D1AD7
  • Sequence:
    • MRRMWATQGL AVALALSVLP GSRALRPGDC EVCISYLGRF YQDLKDRDVT FSPATIENEL 
IKFCREARGK ENRLCYYIGA TDDAATKIIN EVSKPLAHHI PVEKICEKLK KKDSQICELK 
YDKQIDLSTV DLKKLRVKEL KKILDDWGET CKGCAEKSDY IRKINELMPK YAPKAASART 
DL

Genular Protein ID: 2254152303

Symbol: A8K878_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K878

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 HOGENOM 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 4 RefSeq 1 SAM 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 185
  • Mass: 21144
  • Checksum: 31AADC334C6274F0
  • Sequence:
    • MRRMRRMWAT QGLAVALALS VLPGSRALRP GDCEVCISYL GRFYQDLKDR DVTFSPATIE 
NELIKFCREA RGKENRLCYY IGATDDAATK IINEVSKPLA HHIPVEKICE KLKKKDSQIC 
ELKYDKQIDL STVDLKKLRV KELKKILDDW GETCKGCAEK SDYIRKINEL MPKYAPKAAS 
ARTDL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.