Details for: PRRC2A
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 236.9086
Cell Significance Index: -36.8500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 141.1430
Cell Significance Index: -35.8000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 90.7391
Cell Significance Index: -42.8400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 86.8416
Cell Significance Index: -35.2800 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 80.1928
Cell Significance Index: -41.2500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 37.2037
Cell Significance Index: -35.5200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 32.0368
Cell Significance Index: -39.5000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 15.0325
Cell Significance Index: -40.2700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 10.1608
Cell Significance Index: -40.1000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 8.2502
Cell Significance Index: -25.3400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 5.8165
Cell Significance Index: -12.7300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 3.4560
Cell Significance Index: 402.7600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.8811
Cell Significance Index: 25.6700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.5718
Cell Significance Index: 170.9600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.1558
Cell Significance Index: 69.3900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.0532
Cell Significance Index: 54.8600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.0015
Cell Significance Index: 27.2600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.8524
Cell Significance Index: 171.0000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.8059
Cell Significance Index: 55.7400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.7929
Cell Significance Index: 157.3500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.7100
Cell Significance Index: 127.9900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.7084
Cell Significance Index: 87.1000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6988
Cell Significance Index: 113.6500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.6984
Cell Significance Index: 15.1300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.6625
Cell Significance Index: 30.0300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.6166
Cell Significance Index: 72.7200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.6058
Cell Significance Index: 83.2000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.5940
Cell Significance Index: 16.6000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.5608
Cell Significance Index: 306.2600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.4522
Cell Significance Index: 29.1800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.4445
Cell Significance Index: 196.5100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4408
Cell Significance Index: 12.7000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.4341
Cell Significance Index: 22.5500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4250
Cell Significance Index: 152.4500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.3448
Cell Significance Index: 8.6200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2561
Cell Significance Index: 32.8300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.2423
Cell Significance Index: 18.0600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2406
Cell Significance Index: 45.7800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.2374
Cell Significance Index: 16.7900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2347
Cell Significance Index: 23.2200 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.2267
Cell Significance Index: 5.9600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.2118
Cell Significance Index: 9.9600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.1741
Cell Significance Index: 4.9900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1548
Cell Significance Index: 107.0800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.1543
Cell Significance Index: 3.2300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1422
Cell Significance Index: 6.6300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1407
Cell Significance Index: 7.9000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1229
Cell Significance Index: 4.3200 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0893
Cell Significance Index: 11.5400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.0560
Cell Significance Index: 2.8300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.0545
Cell Significance Index: 49.1700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0464
Cell Significance Index: 7.9300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0399
Cell Significance Index: 3.0600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0188
Cell Significance Index: 35.4500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0127
Cell Significance Index: 0.2700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0054
Cell Significance Index: -8.3300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0059
Cell Significance Index: -10.8500 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.0127
Cell Significance Index: -0.1800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0148
Cell Significance Index: -9.4200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0171
Cell Significance Index: -12.5400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0185
Cell Significance Index: -25.1600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0224
Cell Significance Index: -16.9800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0327
Cell Significance Index: -14.8500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0386
Cell Significance Index: -1.0300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0401
Cell Significance Index: -29.6700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0484
Cell Significance Index: -4.9400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0635
Cell Significance Index: -35.8000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0738
Cell Significance Index: -4.6500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0772
Cell Significance Index: -48.1800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0920
Cell Significance Index: -1.5400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1047
Cell Significance Index: -12.0000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1437
Cell Significance Index: -41.3600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1523
Cell Significance Index: -22.1400 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.1527
Cell Significance Index: -1.9600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2106
Cell Significance Index: -44.3500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2240
Cell Significance Index: -11.7600 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.2308
Cell Significance Index: -4.2700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.2745
Cell Significance Index: -9.5400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2966
Cell Significance Index: -9.5000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3468
Cell Significance Index: -36.1100 - Cell Name: peg cell (CL4033014)
Fold Change: -0.3523
Cell Significance Index: -8.1400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.4248
Cell Significance Index: -10.9200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.4263
Cell Significance Index: -12.5200 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.4279
Cell Significance Index: -3.9400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.4287
Cell Significance Index: -4.8700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4352
Cell Significance Index: -34.4700 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.4439
Cell Significance Index: -11.3400 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.4535
Cell Significance Index: -4.9300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.4772
Cell Significance Index: -21.1100 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.5039
Cell Significance Index: -20.6500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5263
Cell Significance Index: -32.2700 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.5361
Cell Significance Index: -7.5200 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.5486
Cell Significance Index: -8.2200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.5860
Cell Significance Index: -8.8300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.6032
Cell Significance Index: -22.8400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.6687
Cell Significance Index: -11.4600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.7636
Cell Significance Index: -26.7500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.7900
Cell Significance Index: -25.1600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.8064
Cell Significance Index: -26.4000 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.8311
Cell Significance Index: -17.6400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1171154349
Symbol: PRC2A_HUMAN
Name: Protein PRRC2A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2156268
Title: A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain.
PubMed ID: 2156268
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 14656967
Title: Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.
PubMed ID: 14656967
DOI: 10.1101/gr.1736803
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8499947
Title: Dense Alu clustering and a potential new member of the NF kappa B family within a 90 kilobase HLA class III segment.
PubMed ID: 8499947
DOI: 10.1038/ng0293-137
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 14667819
Title: Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.
PubMed ID: 14667819
PubMed ID: 15752841
Title: Antibodies generated by a novel DNA vaccination identify the MHC class III encoded BAT2 polypeptide.
PubMed ID: 15752841
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 2157
- Mass: 228863
- Checksum: 7353342E72F0D393
- Sequence:
MSDRSGPTAK GKDGKKYSSL NLFDTYKGKS LEIQKPAVAP RHGLQSLGKV AIARRMPPPA NLPSLKAENK GNDPNVSLVP KDGTGWASKQ EQSDPKSSDA STAQPPESQP LPASQTPASN QPKRPPAAPE NTPLVPSGVK SWAQASVTHG AHGDGGRASS LLSRFSREEF PTLQAAGDQD KAAKERESAE QSSGPGPSLR PQNSTTWRDG GGRGPDELEG PDSKLHHGHD PRGGLQPSGP PQFPPYRGMM PPFMYPPYLP FPPPYGPQGP YRYPTPDGPS RFPRVAGPRG SGPPMRLVEP VGRPSILKED NLKEFDQLDQ ENDDGWAGAH EEVDYTEKLK FSDEEDGRDS DEEGAEGHRD SQSASGEERP PEADGKKGNS PNSEPPTPKT AWAETSRPPE TEPGPPAPKP PLPPPHRGPA GNWGPPGDYP DRGGPPCKPP APEDEDEAWR QRRKQSSSEI SLAVERARRR REEEERRMQE ERRAACAEKL KRLDEKFGAP DKRLKAEPAA PPAAPSTPAP PPAVPKELPA PPAPPPASAP TPETEPEEPA QAPPAQSTPT PGVAAAPTLV SGGGSTSSTS SGSFEASPVE PQLPSKEGPE PPEEVPPPTT PPVPKVEPKG DGIGPTRQPP SQGLGYPKYQ KSLPPRFQRQ QQEQLLKQQQ QHQWQQHQQG SAPPTPVPPS PPQPVTLGAV PAPQAPPPPP KALYPGALGR PPPMPPMNFD PRWMMIPPYV DPRLLQGRPP LDFYPPGVHP SGLVPRERSD SGGSSSEPFD RHAPAMLRER GTPPVDPKLA WVGDVFTATP AEPRPLTSPL RQAADEDDKG MRSETPPVPP PPPYLASYPG FPENGAPGPP ISRFPLEEPG PRPLPWPPGS DEVAKIQTPP PKKEPPKEET AQLTGPEAGR KPARGVGSGG QGPPPPRRES RTETRWGPRP GSSRRGIPPE EPGAPPRRAG PIKKPPPPTK VEELPPKPLE QGDETPKPPK PDPLKITKGK LGGPKETPPN GNLSPAPRLR RDYSYERVGP TSCRGRGRGE YFARGRGFRG TYGGRGRGAR SREFRSYREF RGDDGRGGGT GGPNHPPAPR GRTASETRSE GSEYEEIPKR RRQRGSETGS ETHESDLAPS DKEAPTPKEG TLTQVPLAPP PPGAPPSPAP ARFTARGGRV FTPRGVPSRR GRGGGRPPPQ VCPGWSPPAK SLAPKKPPTG PLPPSKEPLK EKLIPGPLSP VARGGSNGGS NVGMEDGERP RRRRHGRAQQ QDKPPRFRRL KQERENAARG SEGKPSLTLP ASAPGPEEAL TTVTVAPAPR RAAAKSPDLS NQNSDQANEE WETASESSDF TSERRGDKEA PPPVLLTPKA VGTPGGGGGG AVPGISAMSR GDLSQRAKDL SKRSFSSQRP GMERQNRRPG PGGKAGSSGS SSGGGGGGPG GRTGPGRGDK RSWPSPKNRS RPPEERPPGL PLPPPPPSSS AVFRLDQVIH SNPAGIQQAL AQLSSRQGSV TAPGGHPRHK PGLPQAPQGP SPRPPTRYEP QRVNSGLSSD PHFEEPGPMV RGVGGTPRDS AGVSPFPPKR RERPPRKPEL LQEESLPPPH SSGFLGSKPE GPGPQAESRD TGTEALTPHI WNRLHTATSR KSYRPSSMEP WMEPLSPFED VAGTEMSQSD SGVDLSGDSQ VSSGPCSQRS SPDGGLKGAA EGPPKRPGGS SPLNAVPCEG PPGSEPPRRP PPAPHDGDRK ELPREQPLPP GPIGTERSQR TDRGTEPGPI RPSHRPGPPV QFGTSDKDSD LRLVVGDSLK AEKELTASVT EAIPVSRDWE LLPSAAASAE PQSKNLDSGH CVPEPSSSGQ RLYPEVFYGS AGPSSSQISG GAMDSQLHPN SGGFRPGTPS LHPYRSQPLY LPPGPAPPSA LLSGLALKGQ FLDFSTMQAT ELGKLPAGGV LYPPPSFLYS PAFCPSPLPD TSLLQVRQDL PSPSDFYSTP LQPGGQSGFL PSGAPAQQML LPMVDSQLPV VNFGSLPPAP PPAPPPLSLL PVGPALQPPS LAVRPPPAPA TRVLPSPARP FPASLGRAEL HPVELKPFQD YQKLSSNLGG PGSSRTPPTG RSFSGLNSRL KATPSTYSGV FRTQRVDLYQ QASPPDALRW IPKPWERTGP PPREGPSRRA EEPGSRGDKE PGLPPPR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.