Details for: STAM
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 175.3188
Cell Significance Index: -27.2700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 121.9823
Cell Significance Index: -30.9400 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 84.0641
Cell Significance Index: -34.6300 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 75.0229
Cell Significance Index: -35.4200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 69.5619
Cell Significance Index: -28.2600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 29.7724
Cell Significance Index: -28.4300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 24.8914
Cell Significance Index: -30.6900 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 12.2851
Cell Significance Index: -32.9100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 8.5823
Cell Significance Index: -26.3600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.2633
Cell Significance Index: -32.6100 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 5.5195
Cell Significance Index: -12.0800 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 5.5132
Cell Significance Index: 90.8500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 2.5294
Cell Significance Index: 250.2200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.3273
Cell Significance Index: 266.2500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.2638
Cell Significance Index: 205.5500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.0789
Cell Significance Index: 974.1200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.8705
Cell Significance Index: 66.8000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.7986
Cell Significance Index: 86.8600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.7447
Cell Significance Index: 44.7100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.6818
Cell Significance Index: 38.2600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.6597
Cell Significance Index: 236.6400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.6467
Cell Significance Index: 39.7500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.5855
Cell Significance Index: 15.0500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.5707
Cell Significance Index: 113.2600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.5224
Cell Significance Index: 361.3300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.4839
Cell Significance Index: 13.8700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.4579
Cell Significance Index: 30.7900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4510
Cell Significance Index: 13.0000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.4185
Cell Significance Index: 75.4400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3482
Cell Significance Index: 24.0800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3473
Cell Significance Index: 42.7100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3310
Cell Significance Index: 9.2500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.3000
Cell Significance Index: 564.9000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.2831
Cell Significance Index: 6.7900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2499
Cell Significance Index: 15.7500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2491
Cell Significance Index: 12.9400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2423
Cell Significance Index: 33.2800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.2350
Cell Significance Index: 128.3400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.2265
Cell Significance Index: 3.0900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2132
Cell Significance Index: 4.6200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.1589
Cell Significance Index: 18.2100 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.1419
Cell Significance Index: 2.7700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1366
Cell Significance Index: 60.4000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0980
Cell Significance Index: 1.6800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0801
Cell Significance Index: 13.6700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0723
Cell Significance Index: 3.3700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0563
Cell Significance Index: 35.7800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0529
Cell Significance Index: 2.4000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0524
Cell Significance Index: 96.6200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0348
Cell Significance Index: 53.6100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0302
Cell Significance Index: 41.0900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.0237
Cell Significance Index: 1.0500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0133
Cell Significance Index: 6.0300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.0074
Cell Significance Index: 0.2800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0022
Cell Significance Index: -0.0600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0109
Cell Significance Index: -8.0500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0113
Cell Significance Index: -7.0800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.0132
Cell Significance Index: -2.5200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0170
Cell Significance Index: -2.4700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0194
Cell Significance Index: -14.7200 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.0205
Cell Significance Index: -0.5000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0247
Cell Significance Index: -18.1100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0398
Cell Significance Index: -22.4600 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0458
Cell Significance Index: -5.8700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0517
Cell Significance Index: -6.1000 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.0539
Cell Significance Index: -0.8600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0657
Cell Significance Index: -3.0900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0933
Cell Significance Index: -19.6600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1051
Cell Significance Index: -10.7400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1154
Cell Significance Index: -33.2100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1350
Cell Significance Index: -15.7300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1511
Cell Significance Index: -19.5200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1654
Cell Significance Index: -11.7000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.1754
Cell Significance Index: -2.5900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1806
Cell Significance Index: -9.4800 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1952
Cell Significance Index: -4.0500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1996
Cell Significance Index: -7.0200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2153
Cell Significance Index: -22.4200 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.2177
Cell Significance Index: -2.0100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2297
Cell Significance Index: -26.2200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2459
Cell Significance Index: -12.8100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2474
Cell Significance Index: -7.0600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2607
Cell Significance Index: -19.4300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2711
Cell Significance Index: -17.4900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.2863
Cell Significance Index: -6.2700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.2928
Cell Significance Index: -7.3200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3423
Cell Significance Index: -27.1100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.3557
Cell Significance Index: -7.5800 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.3579
Cell Significance Index: -7.6500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3860
Cell Significance Index: -8.1900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.4018
Cell Significance Index: -11.8000 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.4041
Cell Significance Index: -6.0900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.4293
Cell Significance Index: -13.7500 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.4450
Cell Significance Index: -5.5200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.4479
Cell Significance Index: -22.6400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.4550
Cell Significance Index: -7.6200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.5036
Cell Significance Index: -13.4700 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.5108
Cell Significance Index: -10.1000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.5269
Cell Significance Index: -16.7800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.5396
Cell Significance Index: -18.7500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 88492392
Symbol: STAM1_HUMAN
Name: Signal transducing adapter molecule 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8780729
Title: Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAM.
PubMed ID: 8780729
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11687594
Title: Tyrosine phosphorylation mapping of the epidermal growth factor receptor signaling pathway.
PubMed ID: 11687594
PubMed ID: 9407053
Title: Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth.
PubMed ID: 9407053
PubMed ID: 10383417
Title: Possible involvement of a novel STAM-associated molecule 'AMSH' in intracellular signal transduction mediated by cytokines.
PubMed ID: 10383417
PubMed ID: 12551915
Title: STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes.
PubMed ID: 12551915
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 20494825
Title: Mutation of tyrosine residue 857 in the PDGF beta-receptor affects cell proliferation but not migration.
PubMed ID: 20494825
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23166352
Title: Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking.
PubMed ID: 23166352
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24790097
Title: The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4.
PubMed ID: 24790097
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 29742433
Title: TIM-1 Ubiquitination Mediates Dengue Virus Entry.
PubMed ID: 29742433
PubMed ID: 19278655
Title: Hybrid structural model of the complete human ESCRT-0 complex.
PubMed ID: 19278655
PubMed ID: 20150893
Title: VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo.
PubMed ID: 20150893
DOI: 10.1038/emboj.2010.6
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 540
- Mass: 59180
- Checksum: 8D6F07FAE538F36F
- Sequence:
MPLFATNPFD QDVEKATSEM NTAEDWGLIL DICDKVGQSR TGPKDCLRSI MRRVNHKDPH VAMQALTLLG ACVSNCGKIF HLEVCSRDFA SEVSNVLNKG HPKVCEKLKA LMVEWTDEFK NDPQLSLISA MIKNLKEQGV TFPAIGSQAA EQAKASPALV AKDPGTVANK KEEEDLAKAI ELSLKEQRQQ STTLSTLYPS TSSLLTNHQH EGRKVRAIYD FEAAEDNELT FKAGEIITVL DDSDPNWWKG ETHQGIGLFP SNFVTADLTA EPEMIKTEKK TVQFSDDVQV ETIEPEPEPA FIDEDKMDQL LQMLQSTDPS DDQPDLPELL HLEAMCHQMG PLIDEKLEDI DRKHSELSEL NVKVMEALSL YTKLMNEDPM YSMYAKLQNQ PYYMQSSGVS GSQVYAGPPP SGAYLVAGNA QMSHLQSYSL PPEQLSSLSQ AVVPPSANPA LPSQQTQAAY PNTMVSSVQG NTYPSQAPVY SPPPAATAAA ATADVTLYQN AGPNMPQVPN YNLTSSTLPQ PGGSQQPPQP QQPYSQKALL
Genular Protein ID: 4175465425
Symbol: B4DZT2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 429
- Mass: 46912
- Checksum: 8CB84C76D6D0A625
- Sequence:
MVEWTDEFKN DPQLSLISAM IKNLKEQGVT FPAIGSQAAE QAKASPALVA KDPGTVANKK EEEDLAKAIE LSLKEQRQQS TTLSTLYPST SSLLTNHQHE GRKVRAIYDF EAAEDNELTF KAGEIITVLD DSDPNWWKGE THQGIGLFPS NFVTADLTAE PEMIKTEKKT VQFSDDVQVE TIEPEPEPAF IDEDKMDQLL QMLQSTDPSD DQPDLPELLH LEAMCHQMGP LIDEKLEDID RKHSELSELN VKVMEALSLY TKLMNEDPMY SMYAKLQNQP YYMQSSGVSG SQVYAGPPPS GAYLVAGNAQ MSHLQSYSLP PEQLSSLSQA VVPPSANPAL PSQQTQAAYP NTMVSSVQGN TYPSQAPVYS PPPAATAAAA TADVTLYQNA GPNMPQVPNY NLTSSTLPQP GGSQQPPQPQ QPYSQKALL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.