Details for: MLLT10

Gene ID: 8028

Symbol: MLLT10

Ensembl ID: ENSG00000078403

Description: MLLT10 histone lysine methyltransferase DOT1L cofactor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 456.2660
    Cell Significance Index: -70.9700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 268.9997
    Cell Significance Index: -68.2300
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 160.2145
    Cell Significance Index: -66.0000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 158.0733
    Cell Significance Index: -74.6300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 143.8252
    Cell Significance Index: -58.4300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 133.4020
    Cell Significance Index: -68.6200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 61.2364
    Cell Significance Index: -58.4700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 59.8967
    Cell Significance Index: -73.8500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 25.2365
    Cell Significance Index: -67.6100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 20.7622
    Cell Significance Index: -45.4400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 18.8771
    Cell Significance Index: -74.4900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 4.5824
    Cell Significance Index: 257.1400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 3.9317
    Cell Significance Index: 84.0400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 3.4624
    Cell Significance Index: 89.0000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 3.1549
    Cell Significance Index: 242.1100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.0741
    Cell Significance Index: 85.9100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.7019
    Cell Significance Index: 541.9900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.5720
    Cell Significance Index: 510.4300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.3699
    Cell Significance Index: 850.0300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.3106
    Cell Significance Index: 1598.1000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.9768
    Cell Significance Index: 87.4400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.8871
    Cell Significance Index: 71.4600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.8486
    Cell Significance Index: 36.0800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.3933
    Cell Significance Index: 85.6400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.2790
    Cell Significance Index: 86.0000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.1633
    Cell Significance Index: 27.9000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.0775
    Cell Significance Index: 28.7700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.7723
    Cell Significance Index: 22.0400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.7370
    Cell Significance Index: 85.8900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6682
    Cell Significance Index: 120.4500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.6130
    Cell Significance Index: 943.7000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.6092
    Cell Significance Index: 1147.0700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6052
    Cell Significance Index: 98.4300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.5461
    Cell Significance Index: 1007.0800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5159
    Cell Significance Index: 56.1200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.4665
    Cell Significance Index: 6.7100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.4548
    Cell Significance Index: 206.4400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4314
    Cell Significance Index: 53.0500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.4299
    Cell Significance Index: 584.5600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.4238
    Cell Significance Index: 269.1500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3847
    Cell Significance Index: 24.8200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.3227
    Cell Significance Index: 5.5300
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.3002
    Cell Significance Index: 2.6600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2864
    Cell Significance Index: 126.6100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.1903
    Cell Significance Index: 2.3600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1805
    Cell Significance Index: 24.7900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1649
    Cell Significance Index: 90.0800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0740
    Cell Significance Index: 66.7800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0561
    Cell Significance Index: 1.9700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0439
    Cell Significance Index: 0.9500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0249
    Cell Significance Index: 1.1300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0093
    Cell Significance Index: -0.6500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0226
    Cell Significance Index: -2.2400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0346
    Cell Significance Index: -1.8000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0533
    Cell Significance Index: -39.4700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0615
    Cell Significance Index: -45.1000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0627
    Cell Significance Index: -1.6800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0680
    Cell Significance Index: -42.4700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0811
    Cell Significance Index: -61.4000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1039
    Cell Significance Index: -58.5900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1233
    Cell Significance Index: -21.0600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1273
    Cell Significance Index: -1.8800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.1486
    Cell Significance Index: -28.2800
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.1532
    Cell Significance Index: -2.2000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1568
    Cell Significance Index: -16.3300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1709
    Cell Significance Index: -8.8800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1782
    Cell Significance Index: -22.8400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2171
    Cell Significance Index: -62.4600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2193
    Cell Significance Index: -31.8800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.2303
    Cell Significance Index: -6.6400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2318
    Cell Significance Index: -27.3400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2437
    Cell Significance Index: -51.3300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2981
    Cell Significance Index: -30.4500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3392
    Cell Significance Index: -15.9400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3710
    Cell Significance Index: -23.3800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.3777
    Cell Significance Index: -48.8000
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.3938
    Cell Significance Index: -4.9100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4010
    Cell Significance Index: -4.7800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4034
    Cell Significance Index: -18.8100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.4267
    Cell Significance Index: -30.1800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5167
    Cell Significance Index: -59.2000
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.5467
    Cell Significance Index: -13.3400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.6190
    Cell Significance Index: -70.6600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.6632
    Cell Significance Index: -49.4300
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.6709
    Cell Significance Index: -8.9500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.6848
    Cell Significance Index: -14.2100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.6958
    Cell Significance Index: -11.7200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.7578
    Cell Significance Index: -39.7900
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.7717
    Cell Significance Index: -9.7400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.7719
    Cell Significance Index: -19.3000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.7758
    Cell Significance Index: -26.9600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7793
    Cell Significance Index: -61.7200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.8083
    Cell Significance Index: -25.8900
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.8723
    Cell Significance Index: -13.2700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.9687
    Cell Significance Index: -20.5600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.0379
    Cell Significance Index: -63.6300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.0518
    Cell Significance Index: -33.5000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.0631
    Cell Significance Index: -22.6400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.0715
    Cell Significance Index: -35.0800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -1.0779
    Cell Significance Index: -15.9100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MLLT10 is a conserved protein that shares structural similarity with other histone methyltransferases. It is predominantly expressed in cells of the nervous system, epithelial tissues, and cardiac myocytes, suggesting its involvement in the regulation of gene expression in these cell types. MLLT10 has been shown to interact with DOT1L, a H3K4I/3 methyltransferase, to facilitate the methylation of histone H3 lysine 4 and 3. This interaction is crucial for the activation of genes involved in cell growth, proliferation, and survival. **Pathways and Functions:** MLLT10 is involved in several key pathways that regulate gene expression and cellular differentiation. These include: 1. **Chromatin Binding and Nucleosome Remodeling**: MLLT10 facilitates the binding of DOT1L to chromatin, leading to the remodeling of nucleosomes and the activation of gene expression. 2. **Positive Regulation of Transcription by RNA Polymerase II**: MLLT10 promotes the recruitment of RNA polymerase II to gene promoters, resulting in the transcription of genes involved in cell growth and proliferation. 3. **Regulation of Transcription by RNA Polymerase II**: MLLT10 modulates the activity of RNA polymerase II, allowing for the fine-tuning of gene expression in response to various cellular signals. 4. **Protein Binding and Complex Formation**: MLLT10 interacts with various proteins, including DOT1L, to form protein-containing complexes that regulate gene expression and cellular differentiation. **Clinical Significance:** Dysregulation of MLLT10 has been implicated in several human diseases, including: 1. **Cancer**: MLLT10 is often overexpressed in cancer cells, where it promotes the activation of oncogenes and the suppression of tumor suppressor genes. 2. **Neurological Disorders**: Mutations in MLLT10 have been linked to neurological disorders, such as autism spectrum disorder and schizophrenia. 3. **Cardiovascular Disease**: MLLT10 is involved in the regulation of cardiac development and function, and its dysregulation has been implicated in cardiovascular disease. In conclusion, MLLT10 is a critical regulator of gene expression and cellular differentiation, and its dysregulation has significant implications for human disease. Further research is needed to fully elucidate the molecular mechanisms underlying MLLT10's role in human disease and to explore potential therapeutic strategies for the treatment of these disorders.

Genular Protein ID: 2544595272

Symbol: AF10_HUMAN

Name: ALL1-fused gene from chromosome 10 protein

UniProtKB Accession Codes:

P55197 B1ANA8 Q5JT37 Q5VX90 Q66K63

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 3 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 9 Ensembl 8 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PIR 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 6 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7888665

Title: A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia.

PubMed ID: 7888665

PubMed ID: 15851025

Title: hDOT1L links histone methylation to leukemogenesis.

PubMed ID: 15851025

DOI: 10.1016/j.cell.2005.02.020

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10860745

Title: Biochemical analyses of the AF10 protein: the extended LAP/PHD-finger mediates oligomerisation.

PubMed ID: 10860745

DOI: 10.1006/jmbi.2000.3766

PubMed ID: 11423977

Title: The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10.

PubMed ID: 11423977

DOI: 10.1038/sj.onc.1204419

PubMed ID: 11756182

Title: The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex.

PubMed ID: 11756182

DOI: 10.1182/blood.v99.1.275

PubMed ID: 11986236

Title: The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10.

PubMed ID: 11986236

DOI: 10.1182/blood.v99.10.3780

PubMed ID: 17868029

Title: AF10-dependent transcription is enhanced by its interaction with FLRG.

PubMed ID: 17868029

DOI: 10.1042/bc20060131

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 26439302

Title: The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.

PubMed ID: 26439302

DOI: 10.1016/j.molcel.2015.08.019

Sequence Information:

  • Length: 1068
  • Mass: 113320
  • Checksum: 0C4D9B77F61BFEEE
  • Sequence:
    • MVSSDRPVSL EDEVSHSMKE MIGGCCVCSD ERGWAENPLV YCDGHGCSVA VHQACYGIVQ 
VPTGPWFCRK CESQERAARV RCELCPHKDG ALKRTDNGGW AHVVCALYIP EVQFANVSTM 
EPIVLQSVPH DRYNKTCYIC DEQGRESKAA TGACMTCNKH GCRQAFHVTC AQFAGLLCEE 
EGNGADNVQY CGYCKYHFSK LKKSKRGSNR SYDQSLSDSS SHSQDKHHEK EKKKYKEKDK 
HKQKHKKQPE PSPALVPSLT VTTEKTYTST SNNSISGSLK RLEDTTARFT NANFQEVSAH 
TSSGKDVSET RGSEGKGKKS SAHSSGQRGR KPGGGRNPGT TVSAASPFPQ GSFSGTPGSV 
KSSSGSSVQS PQDFLSFTDS DLRNDSYSHS QQSSATKDVH KGESGSQEGG VNSFSTLIGL 
PSTSAVTSQP KSFENSPGDL GNSSLPTAGY KRAQTSGIEE ETVKEKKRKG NKQSKHGPGR 
PKGNKNQENV SHLSVSSASP TSSVASAAGS ITSSSLQKSP TLLRNGSLQS LSVGSSPVGS 
EISMQYRHDG ACPTTTFSEL LNAIHNGIYN SNDVAVSFPN VVSGSGSSTP VSSSHLPQQS 
SGHLQQVGAL SPSAVSSAAP AVATTQANTL SGSSLSQAPS HMYGNRSNSS MAALIAQSEN 
NQTDQDLGDN SRNLVGRGSS PRGSLSPRSP VSSLQIRYDQ PGNSSLENLP PVAASIEQLL 
ERQWSEGQQF LLEQGTPSDI LGMLKSLHQL QVENRRLEEQ IKNLTAKKER LQLLNAQLSV 
PFPTITANPS PSHQIHTFSA QTAPTTDSLN SSKSPHIGNS FLPDNSLPVL NQDLTSSGQS 
TSSSSALSTP PPAGQSPAQQ GSGVSGVQQV NGVTVGALAS GMQPVTSTIP AVSAVGGIIG 
ALPGNQLAIN GIVGALNGVM QTPVTMSQNP TPLTHTTVPP NATHPMPATL TNSASGLGLL 
SDQQRQILIH QQQFQQLLNS QQLTPEQHQA FLYQLMQHHH QQHHQPELQQ LQIPGPTQIP 
INNLLAGTQA PPLHTATTNP FLTIHGDNAS QKVARLSDKT GPVAQEKS

Genular Protein ID: 2120186085

Symbol: Q59EQ6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59EQ6

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 2 SAM 1 SMART 1 SMR 1

Sequence Information:

  • Length: 508
  • Mass: 54362
  • Checksum: 5716B33E100FCC19
  • Sequence:
    • LESGRCELCP HKDGALKRTD NGGWAHVVCA LYIPEVQFAN VSTMEPIVLQ SVPHDRYNKT 
CYICDEQGRE SKAATGACMT CNKHGCRQAF HVTCAQFAGL LCEEEGNGAD NVQYCGYCKY 
HFSKLKKSKR GSNRSYDQSL SDSSSHSQDK HHEKEKKKYK EKDKHKQKHK KQPEPSPALV 
PSLTVTTEKT YTSTSNNSIS GSLKRLEDTT ARFTNANFQE VSAHTSSGKD VSETRGSEGK 
GKKSSAHSSG QRGRKPGGGR NPGTTVSAAS PFPQGSFSGT PGSVKSSSGS SVQSPQDFLS 
FTDSDLRNDS YSHSQQSSAT KDVHKGESGS QEGGVNSFST LIGLPSTSAV TSQPKSFENS 
PGDLGNSSLP TAGYKRAQTS GIEEETVKEK KRKGNKQSKH GPGRPKGNKN QENVSHLSVS 
SASPTSSVAS AAGSITSSSL QKSPTLLRNG SLQSLSVGSS PVGSEISMQY RHDGACPTTT 
FSELLNAIHN DRGDSSTLTK QELKFIVN

Genular Protein ID: 2286197101

Symbol: Q6N002_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6N002

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 RefSeq 2 SAM 2

Sequence Information:

  • Length: 532
  • Mass: 55390
  • Checksum: 8B7B6F719730C4C1
  • Sequence:
    • IEEETVKEKK RKGNKQSKHG PGRPKGNKNQ ENVSHLSVSS ASPTSSVASA AGSITSSSLQ 
KSPTLLRNGS LQSLSVGSSP VGSEISMQYR HDGACPTTSI YNSNDVAVSF PNVVSGSGSS 
TPVSSSHLPQ QSSGHLQQVG ALSPSAVSSA APAVATTQAN TLSGSSLSQA PSHMYGNRSN 
SSMAALIAQS ENNQTDQDLG DNSRNLVGRG SSPRGSLSPR SPVSSLQIRY DQPGNSSLEN 
LPPVAASIEQ LLERQWSEGQ QFLLEQGTPS DILGMLKSLH QLQVENRRLE EQIKNLTAKK 
ERLQLLNAQL SVPFPTITAN PSPSHQIHTF SAQTAPTTDS LNSSKSPHIG NSFLPDNSLP 
VLNQDLTSSG QSTSSSSALS TPPPAGQSPA QQGSGVSGVQ QVNGVTVGAL ASGMQPVTST 
IPAVSAVGGI IGALPGNQLA INGIVGALNG VMQTPVTMSQ NPTPLTHTTV PPNATHPMPA 
TLTNSASGLG LLSDQQRQIL IHQQQFQQLL NSQQLTPNMV KEFSAQIIAW RP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.