Details for: CAPNS1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 334.5651
Cell Significance Index: -52.0400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 190.3066
Cell Significance Index: -48.2700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 137.4447
Cell Significance Index: -56.6200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 122.4840
Cell Significance Index: -49.7600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 118.2320
Cell Significance Index: -55.8200 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 105.2907
Cell Significance Index: -54.1600 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 83.4101
Cell Significance Index: -55.9700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 44.4055
Cell Significance Index: -54.7500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 17.5858
Cell Significance Index: -47.1100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 14.1230
Cell Significance Index: -55.7300 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 12.1343
Cell Significance Index: -37.2700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 9.4353
Cell Significance Index: -20.6500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 2.3923
Cell Significance Index: 22.0300 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 2.3582
Cell Significance Index: 26.7900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.1324
Cell Significance Index: 1164.5800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.9513
Cell Significance Index: 125.8900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.8799
Cell Significance Index: 258.1600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.7565
Cell Significance Index: 316.6400 - Cell Name: peg cell (CL4033014)
Fold Change: 1.7443
Cell Significance Index: 40.3000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.6698
Cell Significance Index: 205.3200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.3238
Cell Significance Index: 61.7200 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.3072
Cell Significance Index: 24.1600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.2947
Cell Significance Index: 35.2400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.2690
Cell Significance Index: 365.1300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.2306
Cell Significance Index: 26.6600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 1.1558
Cell Significance Index: 54.3200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.1015
Cell Significance Index: 57.2200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.0846
Cell Significance Index: 979.2900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.8429
Cell Significance Index: 24.2900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.7759
Cell Significance Index: 126.1900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.6950
Cell Significance Index: 51.8000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.6662
Cell Significance Index: 126.7800 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.6255
Cell Significance Index: 80.8200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6028
Cell Significance Index: 59.6300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.5614
Cell Significance Index: 71.9700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5253
Cell Significance Index: 23.8100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.5054
Cell Significance Index: 101.3900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.4964
Cell Significance Index: 219.4600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.3342
Cell Significance Index: 66.3300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.3091
Cell Significance Index: 21.8600 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.2508
Cell Significance Index: 5.2500 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.2040
Cell Significance Index: 3.6100 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.1522
Cell Significance Index: 4.4700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1277
Cell Significance Index: 21.8100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0819
Cell Significance Index: 2.2900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0707
Cell Significance Index: 25.3500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0457
Cell Significance Index: 34.6000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0312
Cell Significance Index: 0.8400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0219
Cell Significance Index: 16.0700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0063
Cell Significance Index: -11.9400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0190
Cell Significance Index: -35.0000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0213
Cell Significance Index: -32.8400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0217
Cell Significance Index: -0.5800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0236
Cell Significance Index: -17.5100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0321
Cell Significance Index: -43.6300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0333
Cell Significance Index: -20.8100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0421
Cell Significance Index: -4.9600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0440
Cell Significance Index: -4.4900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0530
Cell Significance Index: -33.6500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0587
Cell Significance Index: -33.1300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: -0.0595
Cell Significance Index: -41.1800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0973
Cell Significance Index: -44.1700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1316
Cell Significance Index: -6.9100 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1320
Cell Significance Index: -3.4700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1392
Cell Significance Index: -15.9500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1449
Cell Significance Index: -30.5100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1733
Cell Significance Index: -2.9000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2111
Cell Significance Index: -2.8800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2699
Cell Significance Index: -39.2400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2778
Cell Significance Index: -32.3800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3044
Cell Significance Index: -9.7500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3108
Cell Significance Index: -8.9100 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.3230
Cell Significance Index: -4.8400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.3274
Cell Significance Index: -25.1300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3684
Cell Significance Index: -23.2200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.3920
Cell Significance Index: -27.1100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4347
Cell Significance Index: -49.6200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4418
Cell Significance Index: -34.9900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.4450
Cell Significance Index: -29.9300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4753
Cell Significance Index: -16.5200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.4960
Cell Significance Index: -12.6700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.5263
Cell Significance Index: -54.8000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.5722
Cell Significance Index: -35.1700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.5790
Cell Significance Index: -12.3300 - Cell Name: late promyelocyte (CL0002151)
Fold Change: -0.6060
Cell Significance Index: -4.0200 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.7718
Cell Significance Index: -4.7500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.7846
Cell Significance Index: -44.0300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7929
Cell Significance Index: -48.6100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.8402
Cell Significance Index: -29.5300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.8660
Cell Significance Index: -45.1100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.8812
Cell Significance Index: -9.5800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.8866
Cell Significance Index: -44.8100 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.9149
Cell Significance Index: -37.4900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.9441
Cell Significance Index: -23.6000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -1.0173
Cell Significance Index: -29.0300 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -1.0679
Cell Significance Index: -8.9700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.0778
Cell Significance Index: -47.6800 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -1.0787
Cell Significance Index: -15.1300 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -1.0814
Cell Significance Index: -11.2000 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -1.1152
Cell Significance Index: -15.8800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1866749175
Symbol: CPNS1_HUMAN
Name: Calpain small subunit 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3016651
Title: Nucleotide sequence of a cDNA coding for the small subunit of human calcium-dependent protease.
PubMed ID: 3016651
PubMed ID: 3024120
Title: Gene organization of the small subunit of human calcium-activated neutral protease.
PubMed ID: 3024120
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 10639123
Title: The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.
PubMed ID: 10639123
PubMed ID: 38230350
Title: Biallelic variants in the calpain regulatory subunit CAPNS1 cause pulmonary arterial hypertension.
PubMed ID: 38230350
Sequence Information:
- Length: 268
- Mass: 28316
- Checksum: 17B87A8E47A90632
- Sequence:
MFLVNSFLKG GGGGGGGGGG LGGGLGNVLG GLISGAGGGG GGGGGGGGGG GGGGGGTAMR ILGGVISAIS EAAAQYNPEP PPPRTHYSNI EANESEEVRQ FRRLFAQLAG DDMEVSATEL MNILNKVVTR HPDLKTDGFG IDTCRSMVAV MDSDTTGKLG FEEFKYLWNN IKRWQAIYKQ FDTDRSGTIC SSELPGAFEA AGFHLNEHLY NMIIRRYSDE SGNMDFDNFI SCLVRLDAMF RAFKSLDKDG TGQIQVNIQE WLQLTMYS
Genular Protein ID: 3622624744
Symbol: A0A0C4DGQ5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 322
- Mass: 33786
- Checksum: 52002C65AB6E1123
- Sequence:
MFLVNSFLKG GGGGGGGGGG LGGGLGNVLG GLISGAGGGG GGGGGGGGGG GGGGGGTAMR ILGGVISAIS EAAAQYNPEP PPPRTHYSNI EANESEEVRQ FRRLFAQLAG DDMEVSATEL MNILNKVVTR HPDLKTDGFG IDTCRSMVAV MDSDTTGKLG FEEFKYLWNN IKRWQAIYKQ FDTDRSGTIC SSELPGAFEA AGFHLNEHLY NMIIRRYSDE SGNMDFDNFI SCLVRLDAMF RAFKSLDKDG TGQIQVNIQE VRTPILGYGC LGGPHPSALH TSSELQSPSS YFASRPWVRA KGLVLLGFPV LTLHPPLPSG CS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.